This asticle mainly talks about the role of game in English teaching in middle schools and colleges and also about the importance of teaching games in schools at different levels.
A key feature that distinguishes cancer cells from all other cells is their capability to spread throughout the body.Although how cancer cells collectively migrate by following molecular rules which influence the stat...A key feature that distinguishes cancer cells from all other cells is their capability to spread throughout the body.Although how cancer cells collectively migrate by following molecular rules which influence the state of cell-cell adhesion contacts has been comprehensively formulated,the impact of physical interactions on cell spreading remains less understood.Cumulative effects of physical interactions exist as the interplay between various physical parameters such as(1)tissue surface tension,(2)viscoelasticity caused by collective cell migration,and(3)solid stress accumulated in the cell aggregate core region.This review aims to point out the role of these physical parameters in cancer cell spreading by considering and comparing the rearrangement of various mono-cultured cancer and epithelial model systems such as the fusion of two cell aggregates.While epithelial cells undergo volumetric cell rearrangement driven by the tissue surface tension,which directs cell movement from the surface to the core region of two-aggregate systems,cancer cells rather perform surface cell rearrangement.Cancer cells migrate toward the surface of the two-aggregate system driven by the solid stress while the surface tension is significantly reduced.The solid stress,accumulated in the core region of the two-aggregate system,is capable of suppressing the movement of epithelial cells that can undergo the jamming state transition;however,this stress enhances the movement of cancer cells.We have focused here on the multi-scale rheological modeling approaches that aimed at reproducing and understanding these biological systems.展开更多
Purpose:This study aims to reveal the recent characteristics of school-based teacher development(STD)in China since it is perceived as a key measure to achieve success in raising educational quality in the country.Des...Purpose:This study aims to reveal the recent characteristics of school-based teacher development(STD)in China since it is perceived as a key measure to achieve success in raising educational quality in the country.Design/Approach/Methods:A qualitative research approach with in-depth interviews of 18 teachers at two primary schools in Beijing was used.Findings:Through the lens of cultural-historical activity theory(CHAT),it was observed that the objectives adaptation of teacher communities was made under the control of the District Education Bureau.STD provides the venue for ordinary teachers to learn,understand,and implement the teaching initiatives promoted by the district.Teacher communities at school level therefore implement continuous professional development initiatives promoted by Education Bureau teaching research officers.Originality/Value:This article argues that the administrative style of local government affected teacher community’s object,rules,and division of labor.It also contributes an indigenous interpretation of the CHAT theory.展开更多
文摘This asticle mainly talks about the role of game in English teaching in middle schools and colleges and also about the importance of teaching games in schools at different levels.
基金This work was supported by the Ministry of Education,Science and Technological Development of The Republic of Serbia(Contract No.451-03-68/2022-14/200135).
文摘A key feature that distinguishes cancer cells from all other cells is their capability to spread throughout the body.Although how cancer cells collectively migrate by following molecular rules which influence the state of cell-cell adhesion contacts has been comprehensively formulated,the impact of physical interactions on cell spreading remains less understood.Cumulative effects of physical interactions exist as the interplay between various physical parameters such as(1)tissue surface tension,(2)viscoelasticity caused by collective cell migration,and(3)solid stress accumulated in the cell aggregate core region.This review aims to point out the role of these physical parameters in cancer cell spreading by considering and comparing the rearrangement of various mono-cultured cancer and epithelial model systems such as the fusion of two cell aggregates.While epithelial cells undergo volumetric cell rearrangement driven by the tissue surface tension,which directs cell movement from the surface to the core region of two-aggregate systems,cancer cells rather perform surface cell rearrangement.Cancer cells migrate toward the surface of the two-aggregate system driven by the solid stress while the surface tension is significantly reduced.The solid stress,accumulated in the core region of the two-aggregate system,is capable of suppressing the movement of epithelial cells that can undergo the jamming state transition;however,this stress enhances the movement of cancer cells.We have focused here on the multi-scale rheological modeling approaches that aimed at reproducing and understanding these biological systems.
文摘Purpose:This study aims to reveal the recent characteristics of school-based teacher development(STD)in China since it is perceived as a key measure to achieve success in raising educational quality in the country.Design/Approach/Methods:A qualitative research approach with in-depth interviews of 18 teachers at two primary schools in Beijing was used.Findings:Through the lens of cultural-historical activity theory(CHAT),it was observed that the objectives adaptation of teacher communities was made under the control of the District Education Bureau.STD provides the venue for ordinary teachers to learn,understand,and implement the teaching initiatives promoted by the district.Teacher communities at school level therefore implement continuous professional development initiatives promoted by Education Bureau teaching research officers.Originality/Value:This article argues that the administrative style of local government affected teacher community’s object,rules,and division of labor.It also contributes an indigenous interpretation of the CHAT theory.
