Naturally occurring cembrene-C (1) has been synthesized from geraniol. The key steps were coupling reaction of the sulphone (6) and chloride (8) and selective cyclization of dicarbonyl compound (12) catalyzed by low v...Naturally occurring cembrene-C (1) has been synthesized from geraniol. The key steps were coupling reaction of the sulphone (6) and chloride (8) and selective cyclization of dicarbonyl compound (12) catalyzed by low valent titanium.展开更多
A dicarbonyl precursor of 9-hydroxy-cembrene-C,8-tetrahydropyranoxy-3,7,11,15- tetramethyl-14-oxo-2E,6E,10E-hexdecatrienal,was prepared from farnesyl acetate via four steps.
基金Project supported by the National Natural Science Foundation of China and by the Special Research Grant for Doctoral Sites in Universities
文摘Naturally occurring cembrene-C (1) has been synthesized from geraniol. The key steps were coupling reaction of the sulphone (6) and chloride (8) and selective cyclization of dicarbonyl compound (12) catalyzed by low valent titanium.
文摘A dicarbonyl precursor of 9-hydroxy-cembrene-C,8-tetrahydropyranoxy-3,7,11,15- tetramethyl-14-oxo-2E,6E,10E-hexdecatrienal,was prepared from farnesyl acetate via four steps.