目的:以传统的分层心脏电影成像(segmented cine imaging)为金标准,评估基于压缩感知(compressed sensing,CS)心脏实时电影在评价左心房功能中的价值。方法:纳入健康的志愿者40例和心超提示左心室舒张功能下降的心脏疾病患者31例,基于...目的:以传统的分层心脏电影成像(segmented cine imaging)为金标准,评估基于压缩感知(compressed sensing,CS)心脏实时电影在评价左心房功能中的价值。方法:纳入健康的志愿者40例和心超提示左心室舒张功能下降的心脏疾病患者31例,基于稳态平衡自由进动序列完成分层电影和CS实时电影的左心房数据采集,2名放射科医师独立对图像质量进行定性分析,并用CVI42图像后处理软件获得左心房径线、容积和射血分数(ejection fraction,EF),并同步进行定量分析。结果:CS电影和传统电影的图像质量无明显差异。两种电影获得左心房径线参数有较好的相关性(ICC>0.90)。除了主动射血分数外,两种电影获得的容积及射血分数均有较好的相关性(ICC>0.80)。两种电影获得的左心房二腔心和四腔心横径无明显差异。与金标准相比,CS电影高估了左心房最小容积,但是差距较小[(4.45±11.18)mL,P=0.003]。两种方法获得的左心房最大容积、收缩前容积和被动射血分数差异无统计学意义。CS电影能较好地区分正常人和左心房功能异常的患者。结论:CS电影可用来准确分析左心房径线和容积,尤其是左心房被动射血分数。展开更多
This paper presents a nonlinear profile order scheme for three-dimensional（3D） hybrid radial acquisition applied to self-gated, free-breathing cardiac cine magnetic resonance imaging（MRI）. In self-gated, free-brea...This paper presents a nonlinear profile order scheme for three-dimensional（3D） hybrid radial acquisition applied to self-gated, free-breathing cardiac cine magnetic resonance imaging（MRI）. In self-gated, free-breathing cardiac cine MRI,respiratory and cardiac motions are unpredictable during acquisition, especially for retrospective reconstruction. Therefore,the non-uniformity of the k-space distribution is an issue of great concern during retrospective self-gated reconstruction. A nonlinear profile order with varying azimuthal increments was provided and compared with the existing golden ratio-based profile order. Optimal parameter values for the nonlinear formula were chosen based on simulations. The two profile orders were compared in terms of the k-space distribution and phantom and human image results. An approximately uniform distribution was obtained based on the nonlinear profile order for persons with various heart rates and breathing patterns.The nonlinear profile order provides more stable profile distributions and fewer streaking artifacts in phantom images. In a comparison of human cardiac cine images, the nonlinear profile order provided results comparable to those provided by the golden ratio-based profile order, and the images were suitable for diagnosis. In conclusion, the nonlinear profile order scheme was demonstrated to be insensitive to various motion patterns and more useful for retrospective reconstruction.展开更多
文摘目的:以传统的分层心脏电影成像(segmented cine imaging)为金标准,评估基于压缩感知(compressed sensing,CS)心脏实时电影在评价左心房功能中的价值。方法:纳入健康的志愿者40例和心超提示左心室舒张功能下降的心脏疾病患者31例,基于稳态平衡自由进动序列完成分层电影和CS实时电影的左心房数据采集,2名放射科医师独立对图像质量进行定性分析,并用CVI42图像后处理软件获得左心房径线、容积和射血分数(ejection fraction,EF),并同步进行定量分析。结果:CS电影和传统电影的图像质量无明显差异。两种电影获得左心房径线参数有较好的相关性(ICC>0.90)。除了主动射血分数外,两种电影获得的容积及射血分数均有较好的相关性(ICC>0.80)。两种电影获得的左心房二腔心和四腔心横径无明显差异。与金标准相比,CS电影高估了左心房最小容积,但是差距较小[(4.45±11.18)mL,P=0.003]。两种方法获得的左心房最大容积、收缩前容积和被动射血分数差异无统计学意义。CS电影能较好地区分正常人和左心房功能异常的患者。结论:CS电影可用来准确分析左心房径线和容积,尤其是左心房被动射血分数。
基金supported by the National Natural Science Foundation of China(Grant Nos.81501463,61671026,81571669,and 81671853)the Natural Science Foundation of Guangdong Province,China(Grant No.2014A030310360)+3 种基金Guangdong Innovative Research Team Program of China(Grant No.2011S013)the Basic Research Project of Shenzhen City,China(Grant Nos.JCYJ20140417113430639 and JCYJ20160429172357751)the High-level Oversea Talent Program of Shenzhen City,China(Grant No.KQJSCX20160301144248)Beijing Center for Mathematics and Information Interdisciplinary Sciences of China
文摘This paper presents a nonlinear profile order scheme for three-dimensional（3D） hybrid radial acquisition applied to self-gated, free-breathing cardiac cine magnetic resonance imaging（MRI）. In self-gated, free-breathing cardiac cine MRI,respiratory and cardiac motions are unpredictable during acquisition, especially for retrospective reconstruction. Therefore,the non-uniformity of the k-space distribution is an issue of great concern during retrospective self-gated reconstruction. A nonlinear profile order with varying azimuthal increments was provided and compared with the existing golden ratio-based profile order. Optimal parameter values for the nonlinear formula were chosen based on simulations. The two profile orders were compared in terms of the k-space distribution and phantom and human image results. An approximately uniform distribution was obtained based on the nonlinear profile order for persons with various heart rates and breathing patterns.The nonlinear profile order provides more stable profile distributions and fewer streaking artifacts in phantom images. In a comparison of human cardiac cine images, the nonlinear profile order provided results comparable to those provided by the golden ratio-based profile order, and the images were suitable for diagnosis. In conclusion, the nonlinear profile order scheme was demonstrated to be insensitive to various motion patterns and more useful for retrospective reconstruction.
