The global burden of breast cancer continues to increase largely because of the aging and growth of the world population. More than 1.38 million women worldwide were estimated to be diagnosed with breast cancer in 200...The global burden of breast cancer continues to increase largely because of the aging and growth of the world population. More than 1.38 million women worldwide were estimated to be diagnosed with breast cancer in 2008, accounting for 23% of all diagnosed cancers in women. Given that the 5-year survival rate for breast cancer is now 90%, experiencing breast cancer is ultimately about quality of life. Women treated for breast cancer are facing a life-time risk of developing lymphedema, a chronic condition that occurs in up to 40% of this population and negatively affects breast cancer survivors' quality of life. This review offers an insightful understanding of the condition by providing clinically relevant and evidence based knowledge regarding lymphedema symptoms, diagnosis, risk reduction, and management with the intent to inform health care professionals so that they might be better equipped to care for patients.展开更多
乳腺癌是全球最常见的、女性中致死人数最多的恶性肿瘤。美国国家综合癌症网络(National Comprehensive Cancer Network,NCCN)更新了2023年版的《NCCN乳腺癌风险降低指南》。该指南基于高级别循证医学证据和最新研究进展,针对没有浸润...乳腺癌是全球最常见的、女性中致死人数最多的恶性肿瘤。美国国家综合癌症网络(National Comprehensive Cancer Network,NCCN)更新了2023年版的《NCCN乳腺癌风险降低指南》。该指南基于高级别循证医学证据和最新研究进展,针对没有浸润性乳腺癌或导管原位癌病史的个体,提供了具有规范化指导意义的乳腺癌风险评估和风险降低策略,受到全球临床医生的广泛关注。乳腺癌也是我国女性最高发的恶性肿瘤,由于我国人口基数大,年新增乳腺癌病例数位居全球首位,乳腺癌防控已经成为我国重大的公共卫生难题。本文将结合亚洲女性乳腺结构特点以及我国乳腺癌的流行病学特点,对新版指南内容进行逐一解读,以期为我国的乳腺癌防控提供参考。展开更多
Breast-conservation surgery(BCS) is established as a safe surgical treatment for most patients with early breast cancer. Recently, advances in oncoplastic techniques are capable of preserving the breast form and quali...Breast-conservation surgery(BCS) is established as a safe surgical treatment for most patients with early breast cancer. Recently, advances in oncoplastic techniques are capable of preserving the breast form and quality of life. Although most BCS defects can be managed with primary closure, the aesthetic outcome may be unpredictable. Among technical options, therapeutic reduction mammaplasty(TRM) remains a useful procedure since the BCS defect can be repaired and the preoperative appearance can be improved, resulting in more proportional breasts. As a consequence of rich breast tissue vascularization, the greater part of reduction techniques have based their planning on preserving the pedicle of the nipple-areola complex after tumor removal. Reliable circulation and improvement of a conical shape to the breast are commonly described in TRM reconstructions. With an immediate approach, the surgical process is smooth since both procedures can be carried out in one operative setting. Additionally,it permits wider excision of the tumor, with a superior mean volume of the specimen and potentially reduces the incidence of margin involvement. Regardless of the fact that there is no consensus concerning the best TRM technique, the criteria is determined by the surgeon's experience, the extent/location of glandular tissue resection and the size of the defect in relation to the size of the remaining breast. The main advantages of the technique utilized should include reproducibility, low interference with the oncological treatment and long-term results. The success of the procedure depends on patient selection, coordinated planning and careful intra-operative management.展开更多
文摘The global burden of breast cancer continues to increase largely because of the aging and growth of the world population. More than 1.38 million women worldwide were estimated to be diagnosed with breast cancer in 2008, accounting for 23% of all diagnosed cancers in women. Given that the 5-year survival rate for breast cancer is now 90%, experiencing breast cancer is ultimately about quality of life. Women treated for breast cancer are facing a life-time risk of developing lymphedema, a chronic condition that occurs in up to 40% of this population and negatively affects breast cancer survivors' quality of life. This review offers an insightful understanding of the condition by providing clinically relevant and evidence based knowledge regarding lymphedema symptoms, diagnosis, risk reduction, and management with the intent to inform health care professionals so that they might be better equipped to care for patients.
文摘乳腺癌是全球最常见的、女性中致死人数最多的恶性肿瘤。美国国家综合癌症网络(National Comprehensive Cancer Network,NCCN)更新了2023年版的《NCCN乳腺癌风险降低指南》。该指南基于高级别循证医学证据和最新研究进展,针对没有浸润性乳腺癌或导管原位癌病史的个体,提供了具有规范化指导意义的乳腺癌风险评估和风险降低策略,受到全球临床医生的广泛关注。乳腺癌也是我国女性最高发的恶性肿瘤,由于我国人口基数大,年新增乳腺癌病例数位居全球首位,乳腺癌防控已经成为我国重大的公共卫生难题。本文将结合亚洲女性乳腺结构特点以及我国乳腺癌的流行病学特点,对新版指南内容进行逐一解读,以期为我国的乳腺癌防控提供参考。
文摘Breast-conservation surgery(BCS) is established as a safe surgical treatment for most patients with early breast cancer. Recently, advances in oncoplastic techniques are capable of preserving the breast form and quality of life. Although most BCS defects can be managed with primary closure, the aesthetic outcome may be unpredictable. Among technical options, therapeutic reduction mammaplasty(TRM) remains a useful procedure since the BCS defect can be repaired and the preoperative appearance can be improved, resulting in more proportional breasts. As a consequence of rich breast tissue vascularization, the greater part of reduction techniques have based their planning on preserving the pedicle of the nipple-areola complex after tumor removal. Reliable circulation and improvement of a conical shape to the breast are commonly described in TRM reconstructions. With an immediate approach, the surgical process is smooth since both procedures can be carried out in one operative setting. Additionally,it permits wider excision of the tumor, with a superior mean volume of the specimen and potentially reduces the incidence of margin involvement. Regardless of the fact that there is no consensus concerning the best TRM technique, the criteria is determined by the surgeon's experience, the extent/location of glandular tissue resection and the size of the defect in relation to the size of the remaining breast. The main advantages of the technique utilized should include reproducibility, low interference with the oncological treatment and long-term results. The success of the procedure depends on patient selection, coordinated planning and careful intra-operative management.
