Objective To determine the effects and toxicity of interstitial brachytherapy using iridium 192 on brain malignant gliomas.Methods Between January 1992 and January 1995, 56 patients with anaplastic astrocytoma and ...Objective To determine the effects and toxicity of interstitial brachytherapy using iridium 192 on brain malignant gliomas.Methods Between January 1992 and January 1995, 56 patients with anaplastic astrocytoma and glioblastoma multiforme were treated with stereotactic brachytherapy using temporary high activity iridium 192 sources.Results The median survival for patients receiving brachytherapy was 28 months. The survival rates at 1, 2, 3 years were 92.8%, 83.9% and 71.4% respectively.Conclusions Brachytherapy may improve the control of local tumor and prolong the survival, when used in deep malignant brain gliomas, by temporary implanted high doses of iridium 192 sources.展开更多
文摘Objective To determine the effects and toxicity of interstitial brachytherapy using iridium 192 on brain malignant gliomas.Methods Between January 1992 and January 1995, 56 patients with anaplastic astrocytoma and glioblastoma multiforme were treated with stereotactic brachytherapy using temporary high activity iridium 192 sources.Results The median survival for patients receiving brachytherapy was 28 months. The survival rates at 1, 2, 3 years were 92.8%, 83.9% and 71.4% respectively.Conclusions Brachytherapy may improve the control of local tumor and prolong the survival, when used in deep malignant brain gliomas, by temporary implanted high doses of iridium 192 sources.
