Three dipyrrin-containing metal complexes and a boron dipyrromethene（BODIPY）-containing complex were designed and synthesized. The photophysical properties, electrochemical behaviours and photovoltaic performance we...Three dipyrrin-containing metal complexes and a boron dipyrromethene（BODIPY）-containing complex were designed and synthesized. The photophysical properties, electrochemical behaviours and photovoltaic performance were extensively investigated. Density functional theory calculations were also performed on those complexes These complexes, together with electron-acceptor [6,6]-phenyl-C71-butyric acid methyl ester, were utilized for the fabrication of solution-processed bulk heterojunction solar cells as the electron-donor materials. The more efficient electron acceptor BODIPY segment renders a lower energy gap and a relatively better photovoltaic conversion efficiency of 0.58%. These results prove that BODIPY segment has a great potential for constructing efficient organic solar cell materials.展开更多
Development of cytosolic protein delivery platforms brings new possibilities for various incurable diseases.Strategies based on polymer/protein self-assembly have shown their potential in protein delivery.However,vers...Development of cytosolic protein delivery platforms brings new possibilities for various incurable diseases.Strategies based on polymer/protein self-assembly have shown their potential in protein delivery.However,versatile photocontrolled platforms based on self-assembly for protein delivery are seldom reported.Herein,we report a boron-dipyrromethene(BODIPY)-modified polyamidoamine(PAMAM)with excellent photo-controllability and efficiency for the cytosolic delivery of various proteins.High serum stability was achieved by coating hyaluronic acid and human serum albumin on the surface of BODIPY-modified PAMAM/protein nanoparticles.The nanoparticles under green light irradiation allowed efficient intracellular delivery of multiple cargo proteins with different charges and molecular weights and promoted endosome escape.The study provides valuable guidance for the development of BODIPY derivative-based protein delivery systems and advances the research in intracellular protein delivery.展开更多
Luminescent porous materials have shown various applications such as electronic devices, gas adsorption, energy materials and photocatalysis. Consequently, we designed and prepared a new type borondipyrromethene(BODIP...Luminescent porous materials have shown various applications such as electronic devices, gas adsorption, energy materials and photocatalysis. Consequently, we designed and prepared a new type borondipyrromethene(BODIPY) based porous organic polymer(POP) by using Sonogashira coupling reaction. This POP-1 exhibits high thermal stability with moderate surface area. In addition, POP-1 is highly emissive in a solid state. Due to enrichment of different kinds of heteroatoms in the skeleton of the porous polymer, POP-1 selectively captures carbon dioxide(CO_2) with relative high adsorption selectivity of CO_2/N_2.展开更多
A novel red-emission boron-dipyrromethene（BODIPY） dye with a pyrrole ring was synthesized simply via one-pot reaction. The spectral properties of it were investigated under the conditions of different solvents. The ...A novel red-emission boron-dipyrromethene（BODIPY） dye with a pyrrole ring was synthesized simply via one-pot reaction. The spectral properties of it were investigated under the conditions of different solvents. The results show that the as-prepared BODIPY dye is extremely sensitive to solvent polarity, and the fluorescent emission enhances with the decrease of solvent polarity. In aqueous buffer, the addition of bovine serum albumin leads to a ratiometric change in absorption spectra with an association constant of 1.16×10^6 L/mol. Meanwhile, the fluorescence emission increases greatly at 622 nm but changes slightly at 575 nm. The response time is very short（less than 3 min）, and the changes of color can be noticed by naked eyes. Bovine serum albumin can be detected by this ratiometric fluorescence probe, but other proteins or enzymes cannot be detected by this method, which indicates that this novel dye has high selectivity towards bovine serum albumin. The reason is that bovine serum albumin has suitable hydro- phobic cavities for binding with the dye. In addition, the dye molecule can penetrate cell membrane easily and make a fast fluorescent stain, which makes it a potential probe for living-cell fluorescence imaging.展开更多
基金Supported by the National Natural Science Foundation of China（Nos.21403085, 51402286） and the Science and Technology Development Project of Jilin Province, China（No.20130522009JH）.
文摘Three dipyrrin-containing metal complexes and a boron dipyrromethene（BODIPY）-containing complex were designed and synthesized. The photophysical properties, electrochemical behaviours and photovoltaic performance were extensively investigated. Density functional theory calculations were also performed on those complexes These complexes, together with electron-acceptor [6,6]-phenyl-C71-butyric acid methyl ester, were utilized for the fabrication of solution-processed bulk heterojunction solar cells as the electron-donor materials. The more efficient electron acceptor BODIPY segment renders a lower energy gap and a relatively better photovoltaic conversion efficiency of 0.58%. These results prove that BODIPY segment has a great potential for constructing efficient organic solar cell materials.
基金This work was supported by the Research Grants Council of Hong Kong(Early Career Scheme,No.27115220)Ming Wai Lau Centre for Reparative Medicine Associate Member Program.
文摘Development of cytosolic protein delivery platforms brings new possibilities for various incurable diseases.Strategies based on polymer/protein self-assembly have shown their potential in protein delivery.However,versatile photocontrolled platforms based on self-assembly for protein delivery are seldom reported.Herein,we report a boron-dipyrromethene(BODIPY)-modified polyamidoamine(PAMAM)with excellent photo-controllability and efficiency for the cytosolic delivery of various proteins.High serum stability was achieved by coating hyaluronic acid and human serum albumin on the surface of BODIPY-modified PAMAM/protein nanoparticles.The nanoparticles under green light irradiation allowed efficient intracellular delivery of multiple cargo proteins with different charges and molecular weights and promoted endosome escape.The study provides valuable guidance for the development of BODIPY derivative-based protein delivery systems and advances the research in intracellular protein delivery.
基金Funded by the Natural Science Foundation of China(Nos.21674129 and 21376272)the Post-doctor Foundation of Central South University(No.140050292)
文摘Luminescent porous materials have shown various applications such as electronic devices, gas adsorption, energy materials and photocatalysis. Consequently, we designed and prepared a new type borondipyrromethene(BODIPY) based porous organic polymer(POP) by using Sonogashira coupling reaction. This POP-1 exhibits high thermal stability with moderate surface area. In addition, POP-1 is highly emissive in a solid state. Due to enrichment of different kinds of heteroatoms in the skeleton of the porous polymer, POP-1 selectively captures carbon dioxide(CO_2) with relative high adsorption selectivity of CO_2/N_2.
基金Supported by the National Natural Science Foundation of China（Nos.21222605, 21006009, 21136002, 21376039）, the Fun- damental Research Funds for the Central Universities of China, the Program for New Century Excellent Talents in University, China and the Scientific Research Foundation for the Returned Overseas Chinese Scholars Sponsored by the Ministry of Educa- tion of China（No.44）.
文摘A novel red-emission boron-dipyrromethene（BODIPY） dye with a pyrrole ring was synthesized simply via one-pot reaction. The spectral properties of it were investigated under the conditions of different solvents. The results show that the as-prepared BODIPY dye is extremely sensitive to solvent polarity, and the fluorescent emission enhances with the decrease of solvent polarity. In aqueous buffer, the addition of bovine serum albumin leads to a ratiometric change in absorption spectra with an association constant of 1.16×10^6 L/mol. Meanwhile, the fluorescence emission increases greatly at 622 nm but changes slightly at 575 nm. The response time is very short（less than 3 min）, and the changes of color can be noticed by naked eyes. Bovine serum albumin can be detected by this ratiometric fluorescence probe, but other proteins or enzymes cannot be detected by this method, which indicates that this novel dye has high selectivity towards bovine serum albumin. The reason is that bovine serum albumin has suitable hydro- phobic cavities for binding with the dye. In addition, the dye molecule can penetrate cell membrane easily and make a fast fluorescent stain, which makes it a potential probe for living-cell fluorescence imaging.
