This paper presents a low-power CMOS analog front-end (AFE) IC designed with a selectable on-chip dual AC/DC- coupled paths for bio-sensor applications. The DC-coupled path can be selected to sense a biosignal with us...This paper presents a low-power CMOS analog front-end (AFE) IC designed with a selectable on-chip dual AC/DC- coupled paths for bio-sensor applications. The DC-coupled path can be selected to sense a biosignal with useful DC information, and the AC-coupled path can be selected for sensing the AC content of the biosignal by attenuating the unwanted DC component. The AFE IC includes a DC-coupled instrumentation amplifier (INA), two variable-gain 1st-order low pass filters (LPF) with tunable cut-off frequencies, a fixed gain 2nd-order Sallen-Key high-pass filter (HPF) with tunable cut-off frequencies, a buffer and an 8-bit differential successive approximation register (SAR) ADC. The entire AFE channel is designed and fabricated in a proprietary 0.35-μm CMOS technology. Excluding an external buffer needed to properly drive the ADC, the measured AFE IC consumes only 2.37 μA/channel with an input referred noise of ~40 μVrms in [1 Hz, 1 kHz], and successfully displays proper ECG (electrocardiogram) and electrogram (EGM) waveforms for QRS peaks detection. We expect that the low-power dual-path design of this AFE IC can enable it to periodically record both the AC and the DC signals for proper sensing and calibration for various bio-sensing applications.展开更多
Bio-sensor arrays for multi-channel recording have been developed recently and signal processing platforms for those signals have been studied actively.But it’s thereal situation which these technologies are generall...Bio-sensor arrays for multi-channel recording have been developed recently and signal processing platforms for those signals have been studied actively.But it’s thereal situation which these technologies are generally developed and studied respectively.So the interface design between recording array and signal processing platform is also an important issue to make bio-sensor signal processing system.In this paper,we proposed interface which has unique protocols to control sensor array and operate platform.There are two types of protocols in the interface.One is between sensor array and MCU in platform and the other is between MCU and board for wireless communication.Basically,each protocol has two kinds of modes(single,frame)and it can be extended if needed.展开更多
Mandibular single denture opposed by maxillary natural dentition showed a great problem. However, mandibular implant overdenture treatment has gained considerable recognition. Ten male patients with complete mandibula...Mandibular single denture opposed by maxillary natural dentition showed a great problem. However, mandibular implant overdenture treatment has gained considerable recognition. Ten male patients with complete mandibular edentulous arch and opposing arch have full natural dentition. Patients were divided into two groups. All patients received two endosseous titanium implants. In Group I, patients were rehabilitated with conventional implant retained overdentures. While in Group II, Patients were rehabilitated with occlusal reactive implant overdentures. A Novel proposed biosensor was used to measure the amount of biting force on the implant retained overdenture. Quantitative electromyographic (EMG) signals of the masseter and anterior fibers of temporalis muscles were recorded, filtered and directly interfaced with a computer to represent the data graphically. The mean amplitude (μV), turn, and activity were recorded at the baseline and after three months. The results revealed an increase in the muscle activity in group II after three months as compared to group I. Significant difference in bilateral biting force at the premolar-molar area was found between group I and group II after three months. This study concluded that a resilient implant overdenture denture could be a desirable treatment in mandibular overdenture supported by two implants with resilient attachment and opposing natural dentition due to its easy fabrication and durability in use and increased muscle activity.展开更多
The accuracy of detecting the chlorophyll content in the canopy and leaves of citrus plants based on sensors with different scales and prediction models was investigated for the establishment of an easy and highly-eff...The accuracy of detecting the chlorophyll content in the canopy and leaves of citrus plants based on sensors with different scales and prediction models was investigated for the establishment of an easy and highly-efficient real-time nutrition diagnosis technology in citrus orchards.The fluorescent values of leaves and canopy based on the Multiplex 3.6 sensor,canopy hyperspectral reflectance data based on the FieldSpec4 radiometer and spectral reflectance based on low-altitude multispectral remote sensing were collected from leaves of Shatang mandarin and then analyzed.Additionally,the associations of the leaf SPAD(soil and plant analyzer development)value with the ratio vegetation index(RVI)and normalized differential vegetation index(NDVI)were analyzed.The leaf SPAD value predictive model was established by means of univariate and multiple linear regressions and the partial least squares method.Variable distribution maps of the relative canopy chlorophyll content based on spectral reflectance in the orchard were automatically created.The results showed that the correlations of the SPAD values obtained from the Multiplex 3.6 sensor,FieldSpec4 radiometer and low-altitude multispectral remote sensing were highly significant.The measures of goodness of fit of the predictive models were R^(2)=0.7063,RMSECV=3.7892,RE=5.96%,and RMSEP=3.7760 based on RVI_((570/800)) and R^(2)=0.7343,RMSECV=3.6535,RE=5.49%,and RMSEP=3.3578 based on NDVI[(570,800)(570,950)(700,840)].The technique to create spatial distribution maps of the relative canopy chlorophyll content in the orchard was established based on sensor information that directly reflected the chlorophyll content of the plants in different parts of the orchard,which in turn provides evidence for implementation of orchard productivity evaluation and precision in fertilization management.展开更多
文摘This paper presents a low-power CMOS analog front-end (AFE) IC designed with a selectable on-chip dual AC/DC- coupled paths for bio-sensor applications. The DC-coupled path can be selected to sense a biosignal with useful DC information, and the AC-coupled path can be selected for sensing the AC content of the biosignal by attenuating the unwanted DC component. The AFE IC includes a DC-coupled instrumentation amplifier (INA), two variable-gain 1st-order low pass filters (LPF) with tunable cut-off frequencies, a fixed gain 2nd-order Sallen-Key high-pass filter (HPF) with tunable cut-off frequencies, a buffer and an 8-bit differential successive approximation register (SAR) ADC. The entire AFE channel is designed and fabricated in a proprietary 0.35-μm CMOS technology. Excluding an external buffer needed to properly drive the ADC, the measured AFE IC consumes only 2.37 μA/channel with an input referred noise of ~40 μVrms in [1 Hz, 1 kHz], and successfully displays proper ECG (electrocardiogram) and electrogram (EGM) waveforms for QRS peaks detection. We expect that the low-power dual-path design of this AFE IC can enable it to periodically record both the AC and the DC signals for proper sensing and calibration for various bio-sensing applications.
文摘Bio-sensor arrays for multi-channel recording have been developed recently and signal processing platforms for those signals have been studied actively.But it’s thereal situation which these technologies are generally developed and studied respectively.So the interface design between recording array and signal processing platform is also an important issue to make bio-sensor signal processing system.In this paper,we proposed interface which has unique protocols to control sensor array and operate platform.There are two types of protocols in the interface.One is between sensor array and MCU in platform and the other is between MCU and board for wireless communication.Basically,each protocol has two kinds of modes(single,frame)and it can be extended if needed.
文摘Mandibular single denture opposed by maxillary natural dentition showed a great problem. However, mandibular implant overdenture treatment has gained considerable recognition. Ten male patients with complete mandibular edentulous arch and opposing arch have full natural dentition. Patients were divided into two groups. All patients received two endosseous titanium implants. In Group I, patients were rehabilitated with conventional implant retained overdentures. While in Group II, Patients were rehabilitated with occlusal reactive implant overdentures. A Novel proposed biosensor was used to measure the amount of biting force on the implant retained overdenture. Quantitative electromyographic (EMG) signals of the masseter and anterior fibers of temporalis muscles were recorded, filtered and directly interfaced with a computer to represent the data graphically. The mean amplitude (μV), turn, and activity were recorded at the baseline and after three months. The results revealed an increase in the muscle activity in group II after three months as compared to group I. Significant difference in bilateral biting force at the premolar-molar area was found between group I and group II after three months. This study concluded that a resilient implant overdenture denture could be a desirable treatment in mandibular overdenture supported by two implants with resilient attachment and opposing natural dentition due to its easy fabrication and durability in use and increased muscle activity.
基金supported by the China National Key Research and Development Project(2016YFD0200703)the China National Science&Technology Support Program(2014BAD16B0103)+1 种基金the China Chongqing Science&Technology Support&Demonstration Project(CSTC2014fazktpt80015)the Jiangxi Province 2011 Collaborative Innovation Special Funds“Co-Innovation Center of the South China Mountain Orchard Intelligent Management Technology and Equipment”(Jiangxi Finance Refers to[2014]No.156).
文摘The accuracy of detecting the chlorophyll content in the canopy and leaves of citrus plants based on sensors with different scales and prediction models was investigated for the establishment of an easy and highly-efficient real-time nutrition diagnosis technology in citrus orchards.The fluorescent values of leaves and canopy based on the Multiplex 3.6 sensor,canopy hyperspectral reflectance data based on the FieldSpec4 radiometer and spectral reflectance based on low-altitude multispectral remote sensing were collected from leaves of Shatang mandarin and then analyzed.Additionally,the associations of the leaf SPAD(soil and plant analyzer development)value with the ratio vegetation index(RVI)and normalized differential vegetation index(NDVI)were analyzed.The leaf SPAD value predictive model was established by means of univariate and multiple linear regressions and the partial least squares method.Variable distribution maps of the relative canopy chlorophyll content based on spectral reflectance in the orchard were automatically created.The results showed that the correlations of the SPAD values obtained from the Multiplex 3.6 sensor,FieldSpec4 radiometer and low-altitude multispectral remote sensing were highly significant.The measures of goodness of fit of the predictive models were R^(2)=0.7063,RMSECV=3.7892,RE=5.96%,and RMSEP=3.7760 based on RVI_((570/800)) and R^(2)=0.7343,RMSECV=3.6535,RE=5.49%,and RMSEP=3.3578 based on NDVI[(570,800)(570,950)(700,840)].The technique to create spatial distribution maps of the relative canopy chlorophyll content in the orchard was established based on sensor information that directly reflected the chlorophyll content of the plants in different parts of the orchard,which in turn provides evidence for implementation of orchard productivity evaluation and precision in fertilization management.
