Objective:To evaluate the effect and safety of foot baths with Tangbi Waixi Decoction(TW)in treating patients with diabetic peripheral neuropathy(DPN).Methods:It is a multicenter double-blinded randomized controlled t...Objective:To evaluate the effect and safety of foot baths with Tangbi Waixi Decoction(TW)in treating patients with diabetic peripheral neuropathy(DPN).Methods:It is a multicenter double-blinded randomized controlled trial.Participants with DPN were recruited between November 18,2016 and May 30,2018 from 8 hospitals in China.All patients received basic treatments for glycemic management.Patients received foot baths with TW herbal granules either 66.9 g(intervention group)or 6.69 g(control group)for 30 min once a day for 2 weeks and followed by a 2-week rest,as a therapeutic course.If the Toronto Clinical Scoring System total score(TCSS-TS)6 points,the patients received a total of 3 therapeutic courses(for 12 weeks)and were followed up for 12 weeks.The primary outcome was change in TCSS-TS score at 12 and 24 weeks.Secondary outcomes included changes in bilateral motor nerve conduction velocity(MNCV)and sensory nerve conduction velocity(SNCV)of the median and common peroneal nerve.Safety was also assessed.Results:Totally 632 patients were enrolled,and 317 and 315 were randomized to the intervention and control groups,respectively.After the 12-week intervention,patients in both groups showed significant declines in TCSSTS scores,and significant increases in MNCV and SNCV of the median and common peroneal nerves compared with pre-treatment(P<0.05).The reduction of TCSS-TS score at 12 weeks and the increase of SNCV of median nerve at 24 weeks in the control group were greater than those in the intervention group(P<0.05).The number of adverse events did not differ significantly between groups(P>0.05),and no serious adverse event was related with treatment.Conclusion:Treatment of TW foot baths was safe and significantly benefitted patients with DPN.A low dose of TW appeared to be more effective than a high dose.(Registry No.Chi CTR-IOR-16009331)展开更多
目的探讨每日氯己定擦浴预防ICU患者院内感染的效果。方法通过检索Pubmed、EMBASE、Cochrane Library、Web of Science database、中国知网、万方数据库获得相关文献,由两名研究者独立提取数据,并根据Cochrane风险评估工具进行质量评价...目的探讨每日氯己定擦浴预防ICU患者院内感染的效果。方法通过检索Pubmed、EMBASE、Cochrane Library、Web of Science database、中国知网、万方数据库获得相关文献,由两名研究者独立提取数据,并根据Cochrane风险评估工具进行质量评价,运用Review Manager5.3软件进行相关数据分析。结果最终纳入13个研究,包括12篇英文和1篇中文,5个为随机对照试验,8个为类实验研究。与对照组相比,氯己定擦浴组中心静脉导管相关性血流感染率降低37%(RR=0.64,95%CI:0.55~0.74,P<0.001),皮肤表面耐甲氧西林金黄色葡萄球菌感染率下降45%(RR=0.51,95%CI:0.40~0.64,P<0.001),导管相关性尿路感染率氯己定擦浴组(每千导管日2.41例感染)低于对照组(每千导管日2.43例感染),呼吸机相关性肺炎感染率氯己定擦浴组(每千导管日2.03例感染)低于对照组(每千导管日2.35例感染),但差异均无统计学意义。结论每日氯己定擦浴对ICU患者院内感染有一定程度的预防作用,可能与皮肤表面革兰阳性菌的减少有关。展开更多
We study genuine entanglement among three qubits undergoing a noisy process that includes dissipation, squeezing,and decoherence. We obtain a general solution and analyze the asymptotic quantum states. We find that mo...We study genuine entanglement among three qubits undergoing a noisy process that includes dissipation, squeezing,and decoherence. We obtain a general solution and analyze the asymptotic quantum states. We find that most of these asymptotic states can be genuinely entangled depending upon the parameters of the channel, memory parameter, and the parameters of the initial states. We study Greenberger–Horne–Zeilinger(GHZ) states and W states, mixed with white noise,and determine the conditions for them to be genuinely entangled at infinity. We find that for these mixtures, it is possible to start with a bi-separable state(with a specific mixture of white noise) and end with genuine entangled states. However, the memory parameter μ must be very high. We find that in contrast to the two-qubit case, none of the three-qubit asymptotic states for n → ∞ are genuinely entangled.展开更多
We study the steady-state entanglement and heat current of two coupled qubits, in which two qubits are connected with two independent heat baths(IHBs) or two common heat baths(CHBs). We construct the master equation i...We study the steady-state entanglement and heat current of two coupled qubits, in which two qubits are connected with two independent heat baths(IHBs) or two common heat baths(CHBs). We construct the master equation in the eigenstate representation of two coupled qubits to describe the dynamics of the total system and derive the solutions in the steadystate with stronger coupling regime between two qubits than qubit–baths. We do not make the rotating wave approximation(RWA) for the qubit–qubit interaction, and so we are able to investigate the behaviors of the system in both the strong coupling regime and the weak coupling regime, respectively. In an equilibrium bath, we find that the entanglement decreases with the bath temperature and energy detuning increasing under the strong coupling regime. In the weak coupling regime,the entanglement increases with coupling strength increasing and decreases with the bath temperature and energy detuning increasing. In a nonequilibrium bath, the entanglement without RWA is useful for entanglement at lower temperatures.We also study the heat currents of the two coupled qubits and their variations with the energy detuning, coupling strength and low temperature. In the strong(weak) coupling regime, the heat current increases(decreases) with coupling strength increasing when the temperature of one bath is lower(higher) than the other, and the energy detuning leads to a positive(negative) effect when the temperature is low(high). In the weak coupling regime, the variation trend of heat current is opposite to that of coupling strength for the IHB case and the CHB case.展开更多
A method using electrodialysis to seperate phosphite from spent electroless nickel (EN) plating solution was studied. The major working parameters for the electrodialyzer with our selected membranes such as voltage, c...A method using electrodialysis to seperate phosphite from spent electroless nickel (EN) plating solution was studied. The major working parameters for the electrodialyzer with our selected membranes such as voltage, current and the flow rate of spent EN bath and condensed solution were optimized. Under the optimum operating conditions, spent EN bath could be effectively purified. And then the purified solution was replenished and reused for EN plating. The life of the EN bath was prolonged for more than 17 metal turnovers (M.T.Os). It showed that the electrodialysis method was one of the most effective means for purification and regeneration of spent EN plating baths and for saving resources and reducing waste.展开更多
Palazzo Valentini, a historical site of Rome＇s Provincial Administration, is located at the heart of the city. The building was purchased in 1827 by Vincenzo Valentini, a banker and consul general of the Prussian Cro...Palazzo Valentini, a historical site of Rome＇s Provincial Administration, is located at the heart of the city. The building was purchased in 1827 by Vincenzo Valentini, a banker and consul general of the Prussian Crown. In 1939, with the outbreak of World War II, a fully self-contained, air-raid shelter was built under the courtyard, with an exit tunnel heading onto the Trajan＇s Forum. Archaeological investigations started in 2005 in view of a simple rehabilitation work of the underground level. As work progressed, the sample-plots brought to light new archaeological findings： relics of a huge temple and what remained of two residential houses with thermal baths. We therefore designed an exhibition space with glass surfaces to allow visitors to appreciate the findings while following a path through historical ages： from the 16th-century courtyard to the underground Roman domus （the sumptuous houses of senators and dignitaries of the Roman Empire）, with private baths, to the remains of a Roman temple, and all the way to the Trajan＇s Column pedesta（ by way of the air-raid shelter. Virtual reconstructions, graphic effects, and movies are the means used to revive the hypothetical origina（ appearance of the environments and the daily life of that epoch in order to help us build a prototype of an on-site museum of the third millennium.展开更多
Pointed condyloma in the anus is caused by a virus of human papilloma, marked by the presence of rapidly growing cutaneous verrucae with itching, mild pain and offensive secretion. Diagnosis can be made based on biops...Pointed condyloma in the anus is caused by a virus of human papilloma, marked by the presence of rapidly growing cutaneous verrucae with itching, mild pain and offensive secretion. Diagnosis can be made based on biopsy. The disease is of high recurrence and very difficult to be cured radically. The author combined surgery with external washing with Chinese herbal medicine and achieved quite good results. The following is report of the treatment.展开更多
We present the experimental results of nitrogen-vacancy （NV） electron spin decoherence, which are linked to the coexistence of electron spin bath of nitrogen impurity （PI center） and 13C nuclear spin bath. In prev...We present the experimental results of nitrogen-vacancy （NV） electron spin decoherence, which are linked to the coexistence of electron spin bath of nitrogen impurity （PI center） and 13C nuclear spin bath. In previous works, only one dominant decoherence source is studied： P1 electron spin bath for type-Ⅰb diamond; or 13C nuclear spin bath for type-Ⅱa diamond. In general, the thermal fluctuation from both spin baths can be eliminated by the Hahn echo sequence, resulting in a long coherence time （T2 ） of about 400#8. However, in a high-purity type-Ⅱa diamond where 1℃ nuclear spin bath is the dominant decoherence source, dramatic decreases of NV electron spin T2 time caused by P1 electron spin bath are observed under certain magnetic field. We further apply the engineered Hahn echo sequence to confirm the decoherenee mechanism of multiple spin baths and quantitatively estimate the contribution of P1 electron spin bath. Our results are helpful to understand the NV decoherence mechanisms, which will benefit quantum computing and quantum metrology.展开更多
From 1992 to 1995, 311 cases of chronic osteomyelitis (including 145 cases of hematogenic osteomyelitis, 147 cases of traumatic osteomyelitis, 8 cases of secondary osteomyelitis after local infection, 4 cases due to o...From 1992 to 1995, 311 cases of chronic osteomyelitis (including 145 cases of hematogenic osteomyelitis, 147 cases of traumatic osteomyelitis, 8 cases of secondary osteomyelitis after local infection, 4 cases due to other causes, and 7 cases with cause unknown) were treated by soaking with Ganlingsan liquid. The average treatment course was 69.5 days. The results showed that 260 cases were cured, 26 cases markedly effective, 20 cases improved, and 5 cases ineffective. The evaluation of the function revealed that 150 cases were excellent, 129 cases good, 10 cases improved, and 22 cases poor. 111 patients recovered from abnormal erythrocyte sedimentation rate. External fixation was applied at the same time for the patients accompanied by nonunion of fracture, and the therapeutic effect was also satisfactory.展开更多
基金Supported by the National Science and Technology Support Program(No.2015BAI04B09)。
文摘Objective:To evaluate the effect and safety of foot baths with Tangbi Waixi Decoction(TW)in treating patients with diabetic peripheral neuropathy(DPN).Methods:It is a multicenter double-blinded randomized controlled trial.Participants with DPN were recruited between November 18,2016 and May 30,2018 from 8 hospitals in China.All patients received basic treatments for glycemic management.Patients received foot baths with TW herbal granules either 66.9 g(intervention group)or 6.69 g(control group)for 30 min once a day for 2 weeks and followed by a 2-week rest,as a therapeutic course.If the Toronto Clinical Scoring System total score(TCSS-TS)6 points,the patients received a total of 3 therapeutic courses(for 12 weeks)and were followed up for 12 weeks.The primary outcome was change in TCSS-TS score at 12 and 24 weeks.Secondary outcomes included changes in bilateral motor nerve conduction velocity(MNCV)and sensory nerve conduction velocity(SNCV)of the median and common peroneal nerve.Safety was also assessed.Results:Totally 632 patients were enrolled,and 317 and 315 were randomized to the intervention and control groups,respectively.After the 12-week intervention,patients in both groups showed significant declines in TCSSTS scores,and significant increases in MNCV and SNCV of the median and common peroneal nerves compared with pre-treatment(P<0.05).The reduction of TCSS-TS score at 12 weeks and the increase of SNCV of median nerve at 24 weeks in the control group were greater than those in the intervention group(P<0.05).The number of adverse events did not differ significantly between groups(P>0.05),and no serious adverse event was related with treatment.Conclusion:Treatment of TW foot baths was safe and significantly benefitted patients with DPN.A low dose of TW appeared to be more effective than a high dose.(Registry No.Chi CTR-IOR-16009331)
文摘We study genuine entanglement among three qubits undergoing a noisy process that includes dissipation, squeezing,and decoherence. We obtain a general solution and analyze the asymptotic quantum states. We find that most of these asymptotic states can be genuinely entangled depending upon the parameters of the channel, memory parameter, and the parameters of the initial states. We study Greenberger–Horne–Zeilinger(GHZ) states and W states, mixed with white noise,and determine the conditions for them to be genuinely entangled at infinity. We find that for these mixtures, it is possible to start with a bi-separable state(with a specific mixture of white noise) and end with genuine entangled states. However, the memory parameter μ must be very high. We find that in contrast to the two-qubit case, none of the three-qubit asymptotic states for n → ∞ are genuinely entangled.
基金Project supported by the National Natural Science Foundation of China(Grant Nos.61675115 and 11704221)
文摘We study the steady-state entanglement and heat current of two coupled qubits, in which two qubits are connected with two independent heat baths(IHBs) or two common heat baths(CHBs). We construct the master equation in the eigenstate representation of two coupled qubits to describe the dynamics of the total system and derive the solutions in the steadystate with stronger coupling regime between two qubits than qubit–baths. We do not make the rotating wave approximation(RWA) for the qubit–qubit interaction, and so we are able to investigate the behaviors of the system in both the strong coupling regime and the weak coupling regime, respectively. In an equilibrium bath, we find that the entanglement decreases with the bath temperature and energy detuning increasing under the strong coupling regime. In the weak coupling regime,the entanglement increases with coupling strength increasing and decreases with the bath temperature and energy detuning increasing. In a nonequilibrium bath, the entanglement without RWA is useful for entanglement at lower temperatures.We also study the heat currents of the two coupled qubits and their variations with the energy detuning, coupling strength and low temperature. In the strong(weak) coupling regime, the heat current increases(decreases) with coupling strength increasing when the temperature of one bath is lower(higher) than the other, and the energy detuning leads to a positive(negative) effect when the temperature is low(high). In the weak coupling regime, the variation trend of heat current is opposite to that of coupling strength for the IHB case and the CHB case.
文摘A method using electrodialysis to seperate phosphite from spent electroless nickel (EN) plating solution was studied. The major working parameters for the electrodialyzer with our selected membranes such as voltage, current and the flow rate of spent EN bath and condensed solution were optimized. Under the optimum operating conditions, spent EN bath could be effectively purified. And then the purified solution was replenished and reused for EN plating. The life of the EN bath was prolonged for more than 17 metal turnovers (M.T.Os). It showed that the electrodialysis method was one of the most effective means for purification and regeneration of spent EN plating baths and for saving resources and reducing waste.
文摘Palazzo Valentini, a historical site of Rome＇s Provincial Administration, is located at the heart of the city. The building was purchased in 1827 by Vincenzo Valentini, a banker and consul general of the Prussian Crown. In 1939, with the outbreak of World War II, a fully self-contained, air-raid shelter was built under the courtyard, with an exit tunnel heading onto the Trajan＇s Forum. Archaeological investigations started in 2005 in view of a simple rehabilitation work of the underground level. As work progressed, the sample-plots brought to light new archaeological findings： relics of a huge temple and what remained of two residential houses with thermal baths. We therefore designed an exhibition space with glass surfaces to allow visitors to appreciate the findings while following a path through historical ages： from the 16th-century courtyard to the underground Roman domus （the sumptuous houses of senators and dignitaries of the Roman Empire）, with private baths, to the remains of a Roman temple, and all the way to the Trajan＇s Column pedesta（ by way of the air-raid shelter. Virtual reconstructions, graphic effects, and movies are the means used to revive the hypothetical origina（ appearance of the environments and the daily life of that epoch in order to help us build a prototype of an on-site museum of the third millennium.
文摘Pointed condyloma in the anus is caused by a virus of human papilloma, marked by the presence of rapidly growing cutaneous verrucae with itching, mild pain and offensive secretion. Diagnosis can be made based on biopsy. The disease is of high recurrence and very difficult to be cured radically. The author combined surgery with external washing with Chinese herbal medicine and achieved quite good results. The following is report of the treatment.
基金Supported by the National Basic Research Program of China under Grant Nos 2014CB921402 and 2015CB921103the Strategic Priority Research Program of the Chinese Academy of Sciences under Grant No XDB07010300the National Natural Science Foundation of China under Grant No 11574386
文摘We present the experimental results of nitrogen-vacancy （NV） electron spin decoherence, which are linked to the coexistence of electron spin bath of nitrogen impurity （PI center） and 13C nuclear spin bath. In previous works, only one dominant decoherence source is studied： P1 electron spin bath for type-Ⅰb diamond; or 13C nuclear spin bath for type-Ⅱa diamond. In general, the thermal fluctuation from both spin baths can be eliminated by the Hahn echo sequence, resulting in a long coherence time （T2 ） of about 400#8. However, in a high-purity type-Ⅱa diamond where 1℃ nuclear spin bath is the dominant decoherence source, dramatic decreases of NV electron spin T2 time caused by P1 electron spin bath are observed under certain magnetic field. We further apply the engineered Hahn echo sequence to confirm the decoherenee mechanism of multiple spin baths and quantitatively estimate the contribution of P1 electron spin bath. Our results are helpful to understand the NV decoherence mechanisms, which will benefit quantum computing and quantum metrology.
文摘From 1992 to 1995, 311 cases of chronic osteomyelitis (including 145 cases of hematogenic osteomyelitis, 147 cases of traumatic osteomyelitis, 8 cases of secondary osteomyelitis after local infection, 4 cases due to other causes, and 7 cases with cause unknown) were treated by soaking with Ganlingsan liquid. The average treatment course was 69.5 days. The results showed that 260 cases were cured, 26 cases markedly effective, 20 cases improved, and 5 cases ineffective. The evaluation of the function revealed that 150 cases were excellent, 129 cases good, 10 cases improved, and 22 cases poor. 111 patients recovered from abnormal erythrocyte sedimentation rate. External fixation was applied at the same time for the patients accompanied by nonunion of fracture, and the therapeutic effect was also satisfactory.
