Arrayed waveguide grating is a versatile and scalable integrated light dispersion device,which has been widely adopted in various applications,including,optical communications and optical sensing.Recently,thin-film li...Arrayed waveguide grating is a versatile and scalable integrated light dispersion device,which has been widely adopted in various applications,including,optical communications and optical sensing.Recently,thin-film lithium niobate emerges as a promising photonic integration platform,due to its ability of shrinking largely the size of typical lithium niobate based optical devices.This would also enable multifunctional photonic integrated chips on a single lithium niobate substrate.However,due to the intrinsic anisotropy of the material,to build an arrayed waveguide grating on X-cut thin-film lithium niobate has never been successful.Here,a universal strategy to design anisotropyfree dispersive components on a uniaxial in-plane anisotropic photonic integration platform is introduced for the first time.This leads to the first implementation of arrayed waveguide gratings on X-cut thin-film lithium niobate with various configurations and high-performances.The best insertion loss of 2.4 dB and crosstalk of−24.1 dB is obtained for the fabricated arrayed waveguide grating devices.Applications of such arrayed waveguide gratings as a wavelength router and in a wavelength-division multiplexed optical transmission system are also demonstrated.展开更多
The silicon-based arrayed waveguide grating(AWG)is widely used due to its compact footprint and its compatibility with the mature CMOS process.However,except for AWGs with ridged waveguides of a few micrometers of cro...The silicon-based arrayed waveguide grating(AWG)is widely used due to its compact footprint and its compatibility with the mature CMOS process.However,except for AWGs with ridged waveguides of a few micrometers of cross section,any small process error will cause a large phase deviation in other AWGs,resulting in an increasing cross talk.In this paper,an ultralow cross talk AWG via a tunable microring resonator(MRR)filter is demonstrated on the SOI platform.The measured insertion loss and minimum adjacent cross talk of the designed AWG are approximately 3.2 and-45.1 d B,respectively.Compared with conventional AWG,its cross talk is greatly reduced.展开更多
Miniaturized fiber-Bragg-grating(FBG)interrogators are of interest for applications in the areas where weight and size controlling is important,e.g.,airplanes and aerospace or in-situ monitoring.An ultra-compact high-...Miniaturized fiber-Bragg-grating(FBG)interrogators are of interest for applications in the areas where weight and size controlling is important,e.g.,airplanes and aerospace or in-situ monitoring.An ultra-compact high-precision on-chip interrogator is proposed based on a tailored arrayed waveguide grating(AWG)on a silicon-on-insulator(SOI)platform.The on-chip interrogator enables continuous wavelength interrogation from 1544 nm to 1568 nm with the wavelength accuracy of less than 1 pm[the root-mean-square error(RMSE)is 0.73 pm]over the whole wavelength range.The chip loss is less than 5 dB.The 1×16 AWG is optimized to achieve a large bandwidth and a low noise level at each channel,and the FBG reflection peaks can be detected by multiple output channels of the AWG.The fabricated AWG is utilized to interrogate FBG sensors through the center of gravity(CoG)algorithm.The validation of an on-chip FBG interrogator that works with sub-picometer wavelength accuracy in a broad wavelength range shows large potential for applications in miniaturized fiber optic sensing systems.展开更多
In this work,we present a significant step toward in vivo ophthalmic optical coherence tomography and angiography on a photonic integrated chip.The diffraction gratings used in spectral-domain optical coherence tomogr...In this work,we present a significant step toward in vivo ophthalmic optical coherence tomography and angiography on a photonic integrated chip.The diffraction gratings used in spectral-domain optical coherence tomography can be replaced by photonic integrated circuits comprising an arrayed waveguide grating.Two arrayed waveguide grating designs with 256 channels were tested,which enabled the first chip-based optical coherence tomography and angiography in vivo three-dimensional human retinal measurements.Design 1 supports a bandwidth of 22nm,with which a sensitivity of up to 91 dB(830μW) and an axial resolution of 10.7 pm was measured.Design 2 supports a bandwidth of 48 nm,with which a sensitivity of 90 dB(480μW) and an axial resolution of 6.5μm was measured.The silicon nitride-based integrated optical waveguides were fabricated with a fully CMOS-compatible process,which allows their monolithic co-integration on top of an optoelectronic silicon chip.As a benchmark for chip-based optical coherence tomography,tomograms generated by a commercially available clinical spectral-domain optical coherence tomography system were compared to those acquired with on-chip gratings.The similarities in the tomograms demonstrate the significant clinical potential for further integration of optical coherence tomography on a chip system.展开更多
Technology-assisted ball training systems have become a research hotspot due to their ability to provide quantitative data for guiding athletes to address their areas of improvement.However,traditional tennis training...Technology-assisted ball training systems have become a research hotspot due to their ability to provide quantitative data for guiding athletes to address their areas of improvement.However,traditional tennis training systems still have some limitations;for instance,they are subjective,expensive,heavy,and time-consuming.In this research,an assistant training tennis racket,which consists of arrayed flexible sensors and an inertial measurement unit,has been proposed to comprehensively analyze the representative actions’force and acceleration.Consisting of MXene as the sensitive material and melamine sponge as the substrate(named MMSS),the flexible sensor exhibited an excellent sensitivity of 5.35 kPa^(-1)(1.1-22.2 kPa)due to the formation of a 3D conductive network.Moreover,the sensor retained a high sensitivity of 0.6 k Pa-1in an ultrawide measurement range(22.2-266 kPa).In addition to recognizing the type of hitting action,an artificial intelligence algorithm was introduced to accurately differentiate the five typical motion behaviors with an accuracy rate of 98.2%.This study not only proposes a comprehensive assistant training tennis racket for improving the techniques of tennis enthusiasts but also a new information processing scheme for intelligent sensing and distinction of different movements,which can offer significant application potential in sports big data collection and the Internet of things.展开更多
Deciphering gene function is fundamental to engineering of microbiology.The clustered regularly interspaced short palindromic repeats(CRISPR)system has been adapted for gene repression across a range of hosts,creating...Deciphering gene function is fundamental to engineering of microbiology.The clustered regularly interspaced short palindromic repeats(CRISPR)system has been adapted for gene repression across a range of hosts,creating a versatile tool called CRISPR interference(CRISPRi)that enables genome-scale analysis of gene function.This approach has yielded significant advances in the design of genome-scale CRISPRi libraries,as well as in applica-tions of CRISPRi screening in medical and industrial microbiology.This review provides an overview of the recent progress made in pooled and arrayed CRISPRi screening in microorganisms and highlights representative studies that have employed this method.Additionally,the challenges associated with CRISPRi screening are discussed,and potential solutions for optimizing this strategy are proposed.展开更多
Integrated diffractive optical neural networks(DONNs)have significant potential for complex machine learning tasks with high speed and ultralow energy consumption.However,the on-chip implementation of a high-performan...Integrated diffractive optical neural networks(DONNs)have significant potential for complex machine learning tasks with high speed and ultralow energy consumption.However,the on-chip implementation of a high-performance optical neural network is limited by input dimensions.In contrast to existing photonic neural networks,a space-time interleaving technology based on arrayed waveguides is designed to realize an on-chip DONN with high-speed,high-dimensional,and all-optical input signal modulation.To demonstrate the performance of the on-chip DONN with high-speed space-time interleaving modulation,an on-chip DONN with a designed footprint of 0.0945 mm~2is proposed to resolve the vowel recognition task,reaching a computation speed of about 1.4×10^(13)operations per second and yielding an accuracy of 98.3%in numerical calculation.In addition,the function of the specially designed arrayed waveguides for realizing parallel signal inputs using space-time conversion has been verified experimentally.This method can realize the on-chip DONN with higher input dimension and lower energy consumption.展开更多
The present study reports an improved PCR-based technique that allows quick and effective screening of cDNA libraries. First, the cDNA library was arrayed as follow: about 3 X 10’ cDNA clones were multiplied as indiv...The present study reports an improved PCR-based technique that allows quick and effective screening of cDNA libraries. First, the cDNA library was arrayed as follow: about 3 X 10’ cDNA clones were multiplied as individual plaques on solid medium in 24-well culture dishes at 1 200 plaque forming units per well. The phage suspension of each well was transferred to an individual microcentrifuge tube in 72-tube box. Then, box pool, row pools and column pools were set up that respectively represent a 72-tube box, rows and columns within the box. To screen a specific target cDNA,primers specific for novel ESTs ob- tained in our laboratory were employed to conduct PCR in a hierarchy mode. PCR began with the box pools, resulting in the identification of some Positive box pools. Then PCR went down to the row and col- umn pools of the positive box. The intersection of the positive row (s) and column (s) revealed the candi- date positive tubes. The specificity of PCR products were meanwhile checked by restriction enzyme diges- tion. Finally, hybridization was carried out to get single specific cDNA clomes from the positive tubes. This PCR-based technique features high specificity, high efficiency and less-cost in large-scale cDNA library screening. Our initial implementation of the technique resulted in the isolation of three longer different cD- NA clones from a human fetal brain cDNA library. Thus this improved technique can serve as an alterna-tive to the time-consuming and laborious conventional hybridization-based method for screening cDNA li-brary.展开更多
In this paper, based on the principle of Arrayed Waveguide Grating (AWG)theory, some important parameters are optimized for polymer AWG around the central wavelength of1.55μm with the wavelength spacing of 1.6 nm. Th...In this paper, based on the principle of Arrayed Waveguide Grating (AWG)theory, some important parameters are optimized for polymer AWG around the central wavelength of1.55μm with the wavelength spacing of 1.6 nm. Then, a 9 X 9 polymer AWG is designed and thefabricating process are described . The cladding material is poly-methyl-methacrylate-co-glyciclylmethacrylate (PMMA-GMA) and the core material is the mixture of PMMA-GMA and bis-phonel-A epoxy. Inorder to obtain a better shape of the waveguide after the Reactive Ion Etching (RIE) using oxygen,an aluminum mask is used on polymer instead of conventional photoresist as mask in the fabricationprocess. The measuring results indicate that the fabricated optical waveguide achieves single-modetransmission.展开更多
A 16 channel arrayed waveguide grating demultiplexer with 200 GHz channel spacing based on Si nanowire waveguides is designed. The transmission spectra response simulated by transmission function method shows that the...A 16 channel arrayed waveguide grating demultiplexer with 200 GHz channel spacing based on Si nanowire waveguides is designed. The transmission spectra response simulated by transmission function method shows that the device has channel spacing of 1.6 nm and crosstalk of 31 dB. The device is fabricated by 193 nm deep UV lithography in silicon-on-substrate. The demultiplexing characteristics are observed with crosstalk of 5-8 dB, central channel＇s insertion loss of 2.2 dB, flee spectral range of 24.7 nm and average channel spacing of 1.475 nm. The cause of the spectral distortion is analyzed specifically.展开更多
We have provided optical simulations of the evanescently coupled waveguide photodiodes integrated with a 13- channels AWGs. The photodiode could exhibit high internal efficiency by appropriate choice of layers geometr...We have provided optical simulations of the evanescently coupled waveguide photodiodes integrated with a 13- channels AWGs. The photodiode could exhibit high internal efficiency by appropriate choice of layers geometry and refrac- tive index. Aseamless joint structure has been designed and fabricated for integrating the output waveguides of AWGs with the evanescently coupled waveguide photodiode array. The highest simulation quantum efficiency could achieve 92% when the matching layer thickfiess of the PD is 120 nm and the insertion length is 2 μm. The fabricated PD with 320-nm-thick match.ing layer and 2-μm-length insertion matching layer present a responsivity of 0.87 A/W.展开更多
Based on transmission theory, a 17 x 17 polymer arrayed waveguide grating （AWG） multiplexer para meter optimization is performed, and the influence of the fabrication results on the transmission characteristics are ...Based on transmission theory, a 17 x 17 polymer arrayed waveguide grating （AWG） multiplexer para meter optimization is performed, and the influence of the fabrication results on the transmission characteristics are analyzed. In this paper, we mainly discuss three of the main errors in the fabrication of polymer AWG devices. One is 3n 1, which is caused by the tuning of the core refractive index n 1, the second is 8b, which results from the rotating-coating of the core thickness b, and the other is the non-ideal core cross-section, which is caused by steam redissolution. The effects of the above fabrication errors on the transmission characteristics of the AWG device are investigated, and compensation techniques are proposed. By comparing the theoretical simulation and experimental results, the shift in the transmission spectrum is reduced by 0.028 nm, the 3 dB bandwidth is increased by about 0.036 nm, the insertion loss is reduced by about 3 dB for the central channel and 4.5 dB for the edge channels, and the crosstalk is reduced by 1.5 dB.展开更多
Integrated spectrometers with both wide optical bandwidths and high spectral resolutions are required in applications such as spectral domain optical coherence tomography(SD-OCT).Here we propose a compact integrated s...Integrated spectrometers with both wide optical bandwidths and high spectral resolutions are required in applications such as spectral domain optical coherence tomography(SD-OCT).Here we propose a compact integrated scanning spectrometer by using a tunable micro-ring resonator(MRR)integrated with a single arrayed waveguide grating for operation in the 1265-1335-nm range.The spectral resolution of the spectrometer is determined by the quality factor of the MRR,and the optical bandwidth is defined by the free spectral range of the arrayed waveguide grating.The spectrometer is integrated with on-chip germanium photodetectors,which enable direct electrical readout.A 70-nm optical bandwidth and a 0.2-nm channel spacing enabled by scanning the MRR across one free spectral range are demonstrated,which offer a total of350 wavelength channels with 31-kHz wavelength scanning speed.The integrated spectrometer is applied to measure different spectra and the interference signals from an SD-OCT system,which shows its great potential for future applications in sensing and imaging systems.展开更多
A 16-channel dual tuning wavelength division multiplexer/demultiplexer based on silicon on insulator platform is demonstrated, which is both peak wavelength tunable and output optical power tunable. The wavelength div...A 16-channel dual tuning wavelength division multiplexer/demultiplexer based on silicon on insulator platform is demonstrated, which is both peak wavelength tunable and output optical power tunable. The wavelength division multiplexer/demultiplexer consists of an arrayed waveguide grating for wavelength division multiplexing/demultiplexing, a heater for peak wavelength tuning and a variable optical attenuator based on p–i–n carrier-injection structure for optical power tuning. The experimental results show that the insertion loss on chip of the device is 3.7 dB–5.7 dB and the crosstalk is 7.5 dB–9 dB. For the tunability of the peak wavelength, 1.058-nm wavelength tunability is achieved with 271.2-mW power consumption, and the average modulation efficiency is 3.9244 nm/W; for the tunability of the optical power, the optical power equalization is achieved in all 16 channels, 20-dB attenuation is achieved with 144.07-mW power consumption,and the raise/fall time of VOA is 35 ns/42 ns.展开更多
One fiber radio scheme using shifted prime codes for interference elimination is proposed for optical code-division multiple-access (OCDMA) network. By taking advantage of the cyclic property of the shifted prime code...One fiber radio scheme using shifted prime codes for interference elimination is proposed for optical code-division multiple-access (OCDMA) network. By taking advantage of the cyclic property of the shifted prime codes in the same code groups, the proposed compact decoder is low cost and suitable to be used in the task manager node in the applications of wireless sensor networks. The performance comparison for sev-eral OCDMA-based fiber radio networks is also given to clarify the advantage of the proposed one.展开更多
We proposed an arrayed waveguide granting （AWG） based 10 Gbps full duplex wavelength division multiplexing passive optical network （WDM-PON） utiliz- ing a return-to-zero differential phase shift keying （RZ- DPSK...We proposed an arrayed waveguide granting （AWG） based 10 Gbps full duplex wavelength division multiplexing passive optical network （WDM-PON） utiliz- ing a return-to-zero differential phase shift keying （RZ- DPSK） modulation technique for down-link direction and then re-modulation of the downlink （DL） signal for the uplink （UL） direction using intensity modulation technique （OOK） with a data rate of 10 Gbps per channel. A successful cost effective colorless WDM-PON full duplex transmission operation for a data rate of 10Gbps per channel, with a channel spacing of 60 GHz over a distance of 25 km without any optical amplification and dispersion compensation is achieved within low power penalty.展开更多
The design and fabrication of a compact and low-cost 4×25-Gb/s transmitter optical sub-assembly(TOSA) and receiver optical sub-assembly(ROSA) using a hybrid integrated technique are reported. TOSA and ROSA are de...The design and fabrication of a compact and low-cost 4×25-Gb/s transmitter optical sub-assembly(TOSA) and receiver optical sub-assembly(ROSA) using a hybrid integrated technique are reported. TOSA and ROSA are developed without thermoelectric cooler for coarse wavelength division multiplexing applications. Physical dimension of the packaged optical subassembly is limited to 11.5 mm×5.4 mm×5.4 mm. The design of TOSA and ROSA is employed using a silica-based arrayed waveguide grating chip to select the specific channel wavelength at O-band. In TOSA, the wavelength of four 1.3-μm discrete directly modulated laser chips is well controlled based on the reconstruction equivalent chirp technique. In the back-to-back transmission test, bit error rates for all lanes of cascade of the TOSA and ROSA are small. A clear opening eye diagram is obtained.展开更多
A 13-channel, InP-based arrayed waveguide grating （AWG） is designed and fabricated in which the on-chip loss of the central channel is about -5 dB and the crosstalk is less than -23 dB in the center of the spectrum ...A 13-channel, InP-based arrayed waveguide grating （AWG） is designed and fabricated in which the on-chip loss of the central channel is about -5 dB and the crosstalk is less than -23 dB in the center of the spectrum response. However, the central wavelength and channel spacing are deviated from the design values. To improve their accuracy, an optimized design is adopted to compensate the process error. As a result, the central wavelength 1549.9 nm and channel spacing 1.59 nm are obtained in the experiment, while their design values are 1549.32 nm and 1.6 nm, respectively. The route capability and thermo-optic characteristic of the AWG are also discussed in detail.展开更多
An optical network is a type of data communication network built with optical fibre technology. It utilizes optical fibre cables as the primary communication medium for converting data and passing data as light pulses...An optical network is a type of data communication network built with optical fibre technology. It utilizes optical fibre cables as the primary communication medium for converting data and passing data as light pulses between sender and receiver nodes. The major issue in optical networking is disjoints that occur in the network. A polynomial time algorithm Wavelength Division Multiplexing-Passive Optical Networking (WDM-PON) computes disjoints of an optical network and reduces the count of disjoints that occur in the network by separating Optical Network Units (ONU) into several virtual point-to-point connections. The Arrayed Waveguide Grating (AWG) filter is included in WDM-PON to avoid the traffic in the network thereby increasing the bandwidth capacity. In case of a failure or disjoint Ant Colony Optimization (ACO) algorithm is used to find the optimized shortest path for re-routing. For enhanced security, modified Rivert Shamir Adleman (RSA) algorithm encrypts the message during communication between the nodes. The efficiency is found to be improved in terms of delay in packet delivery, longer optical reach, optimized shortest path, packet error rate.展开更多
基金National Natural Science Foundation of China(NSFC)(62135012,92150302,U23B2047,62321166651)Leading Innovative and Entrepreneur Team Introduction Program of Zhejiang(2021R01001)“Pioneer”and“Leading Goose”R&D Program of Zhejiang(2023C01139).
文摘Arrayed waveguide grating is a versatile and scalable integrated light dispersion device,which has been widely adopted in various applications,including,optical communications and optical sensing.Recently,thin-film lithium niobate emerges as a promising photonic integration platform,due to its ability of shrinking largely the size of typical lithium niobate based optical devices.This would also enable multifunctional photonic integrated chips on a single lithium niobate substrate.However,due to the intrinsic anisotropy of the material,to build an arrayed waveguide grating on X-cut thin-film lithium niobate has never been successful.Here,a universal strategy to design anisotropyfree dispersive components on a uniaxial in-plane anisotropic photonic integration platform is introduced for the first time.This leads to the first implementation of arrayed waveguide gratings on X-cut thin-film lithium niobate with various configurations and high-performances.The best insertion loss of 2.4 dB and crosstalk of−24.1 dB is obtained for the fabricated arrayed waveguide grating devices.Applications of such arrayed waveguide gratings as a wavelength router and in a wavelength-division multiplexed optical transmission system are also demonstrated.
基金supported by the National Key Research and Development Program of China(No.2018YFB2200500)the Yunnan Provincial Foundation Program(No.202201AT070202)the National Natural Science Foundation of China(No.62065010)。
文摘The silicon-based arrayed waveguide grating(AWG)is widely used due to its compact footprint and its compatibility with the mature CMOS process.However,except for AWGs with ridged waveguides of a few micrometers of cross section,any small process error will cause a large phase deviation in other AWGs,resulting in an increasing cross talk.In this paper,an ultralow cross talk AWG via a tunable microring resonator(MRR)filter is demonstrated on the SOI platform.The measured insertion loss and minimum adjacent cross talk of the designed AWG are approximately 3.2 and-45.1 d B,respectively.Compared with conventional AWG,its cross talk is greatly reduced.
基金supported by the National Natural Science Foundation of China (Grant Nos.12202310,12202309,1233201712202309,and 12332017)Chinesisch-Deutsche Zentrum für Wissenschaftsförderung (Grant No.GZ1575)China Postdoctoral Science Foundation (Grant No.2022M712357).
基金This work wasssupported by the National Natural Science Foundation of China(Grant Nos.62020106002 and 61735017)Innovation Project of Zhejiang Laboratory(Grant No.2021MG0AL01)+2 种基金the Youth Foundation of Zhejiang Laboratory(Grant No.2020MC0AA08)Major Scientific Research Project of Zhejiang Laboratory(Grant No.2019MC0AD02)National Key Basic Research Program of China(Grant No.2021YFC2401403).
文摘Miniaturized fiber-Bragg-grating(FBG)interrogators are of interest for applications in the areas where weight and size controlling is important,e.g.,airplanes and aerospace or in-situ monitoring.An ultra-compact high-precision on-chip interrogator is proposed based on a tailored arrayed waveguide grating(AWG)on a silicon-on-insulator(SOI)platform.The on-chip interrogator enables continuous wavelength interrogation from 1544 nm to 1568 nm with the wavelength accuracy of less than 1 pm[the root-mean-square error(RMSE)is 0.73 pm]over the whole wavelength range.The chip loss is less than 5 dB.The 1×16 AWG is optimized to achieve a large bandwidth and a low noise level at each channel,and the FBG reflection peaks can be detected by multiple output channels of the AWG.The fabricated AWG is utilized to interrogate FBG sensors through the center of gravity(CoG)algorithm.The validation of an on-chip FBG interrogator that works with sub-picometer wavelength accuracy in a broad wavelength range shows large potential for applications in miniaturized fiber optic sensing systems.
基金The authors thank Rene Werkmeister for data acquisition and permission to use the data from the commercial benchmark system and EXALOS AG for the booster amplifier.E.A.R.greatly acknowledges fruitful discussions with Fabian Placzek.This work was carried out in the framework of project COHESION,No.848588,funded by the Austrian Research Promotion Agency(FFG).This research has received funding from the European Union's Horizon 2020 research and innovation program under grant agreement No.688173(OCTCHIP).DJ.H.gratefully acknowledges financial support from the European Research Council(ERC)(No.640396 OPTIMALZ).
文摘In this work,we present a significant step toward in vivo ophthalmic optical coherence tomography and angiography on a photonic integrated chip.The diffraction gratings used in spectral-domain optical coherence tomography can be replaced by photonic integrated circuits comprising an arrayed waveguide grating.Two arrayed waveguide grating designs with 256 channels were tested,which enabled the first chip-based optical coherence tomography and angiography in vivo three-dimensional human retinal measurements.Design 1 supports a bandwidth of 22nm,with which a sensitivity of up to 91 dB(830μW) and an axial resolution of 10.7 pm was measured.Design 2 supports a bandwidth of 48 nm,with which a sensitivity of 90 dB(480μW) and an axial resolution of 6.5μm was measured.The silicon nitride-based integrated optical waveguides were fabricated with a fully CMOS-compatible process,which allows their monolithic co-integration on top of an optoelectronic silicon chip.As a benchmark for chip-based optical coherence tomography,tomograms generated by a commercially available clinical spectral-domain optical coherence tomography system were compared to those acquired with on-chip gratings.The similarities in the tomograms demonstrate the significant clinical potential for further integration of optical coherence tomography on a chip system.
基金supported by the National Key R&D Program of China(Grant No.2019YFE0120300)the National Natural Science Foundation of China(Grant Nos.62171414,52175554,52205608,62001431)+1 种基金the Fundamental Research Program of Shanxi Province(Grant Nos.20210302123059,20210302124610)Program for the Innovative Talents of Higher Education Institutions of Shanxi。
文摘Technology-assisted ball training systems have become a research hotspot due to their ability to provide quantitative data for guiding athletes to address their areas of improvement.However,traditional tennis training systems still have some limitations;for instance,they are subjective,expensive,heavy,and time-consuming.In this research,an assistant training tennis racket,which consists of arrayed flexible sensors and an inertial measurement unit,has been proposed to comprehensively analyze the representative actions’force and acceleration.Consisting of MXene as the sensitive material and melamine sponge as the substrate(named MMSS),the flexible sensor exhibited an excellent sensitivity of 5.35 kPa^(-1)(1.1-22.2 kPa)due to the formation of a 3D conductive network.Moreover,the sensor retained a high sensitivity of 0.6 k Pa-1in an ultrawide measurement range(22.2-266 kPa).In addition to recognizing the type of hitting action,an artificial intelligence algorithm was introduced to accurately differentiate the five typical motion behaviors with an accuracy rate of 98.2%.This study not only proposes a comprehensive assistant training tennis racket for improving the techniques of tennis enthusiasts but also a new information processing scheme for intelligent sensing and distinction of different movements,which can offer significant application potential in sports big data collection and the Internet of things.
基金supported by the National Key R&D Program of China(2018YFA0901500)the National Natural Science Foundation of China(32222004 and 32270101)the Youth Innovation Promotion Association of Chinese Academy of Sciences(2021177).
文摘Deciphering gene function is fundamental to engineering of microbiology.The clustered regularly interspaced short palindromic repeats(CRISPR)system has been adapted for gene repression across a range of hosts,creating a versatile tool called CRISPR interference(CRISPRi)that enables genome-scale analysis of gene function.This approach has yielded significant advances in the design of genome-scale CRISPRi libraries,as well as in applica-tions of CRISPRi screening in medical and industrial microbiology.This review provides an overview of the recent progress made in pooled and arrayed CRISPRi screening in microorganisms and highlights representative studies that have employed this method.Additionally,the challenges associated with CRISPRi screening are discussed,and potential solutions for optimizing this strategy are proposed.
基金supported by the National Natural Science Foundation of China(NSFC)(No.62135009)the Beijing Municipal Science&Technology Commission,Administrative Commission of Zhongguancun Science Park(No.Z221100005322010)。
文摘Integrated diffractive optical neural networks(DONNs)have significant potential for complex machine learning tasks with high speed and ultralow energy consumption.However,the on-chip implementation of a high-performance optical neural network is limited by input dimensions.In contrast to existing photonic neural networks,a space-time interleaving technology based on arrayed waveguides is designed to realize an on-chip DONN with high-speed,high-dimensional,and all-optical input signal modulation.To demonstrate the performance of the on-chip DONN with high-speed space-time interleaving modulation,an on-chip DONN with a designed footprint of 0.0945 mm~2is proposed to resolve the vowel recognition task,reaching a computation speed of about 1.4×10^(13)operations per second and yielding an accuracy of 98.3%in numerical calculation.In addition,the function of the specially designed arrayed waveguides for realizing parallel signal inputs using space-time conversion has been verified experimentally.This method can realize the on-chip DONN with higher input dimension and lower energy consumption.
基金National Natural Science Fund!(39392900 ) 863 High-tech Project Fund of China!(102-10-03-02 )
文摘The present study reports an improved PCR-based technique that allows quick and effective screening of cDNA libraries. First, the cDNA library was arrayed as follow: about 3 X 10’ cDNA clones were multiplied as individual plaques on solid medium in 24-well culture dishes at 1 200 plaque forming units per well. The phage suspension of each well was transferred to an individual microcentrifuge tube in 72-tube box. Then, box pool, row pools and column pools were set up that respectively represent a 72-tube box, rows and columns within the box. To screen a specific target cDNA,primers specific for novel ESTs ob- tained in our laboratory were employed to conduct PCR in a hierarchy mode. PCR began with the box pools, resulting in the identification of some Positive box pools. Then PCR went down to the row and col- umn pools of the positive box. The intersection of the positive row (s) and column (s) revealed the candi- date positive tubes. The specificity of PCR products were meanwhile checked by restriction enzyme diges- tion. Finally, hybridization was carried out to get single specific cDNA clomes from the positive tubes. This PCR-based technique features high specificity, high efficiency and less-cost in large-scale cDNA library screening. Our initial implementation of the technique resulted in the isolation of three longer different cD- NA clones from a human fetal brain cDNA library. Thus this improved technique can serve as an alterna-tive to the time-consuming and laborious conventional hybridization-based method for screening cDNA li-brary.
文摘In this paper, based on the principle of Arrayed Waveguide Grating (AWG)theory, some important parameters are optimized for polymer AWG around the central wavelength of1.55μm with the wavelength spacing of 1.6 nm. Then, a 9 X 9 polymer AWG is designed and thefabricating process are described . The cladding material is poly-methyl-methacrylate-co-glyciclylmethacrylate (PMMA-GMA) and the core material is the mixture of PMMA-GMA and bis-phonel-A epoxy. Inorder to obtain a better shape of the waveguide after the Reactive Ion Etching (RIE) using oxygen,an aluminum mask is used on polymer instead of conventional photoresist as mask in the fabricationprocess. The measuring results indicate that the fabricated optical waveguide achieves single-modetransmission.
基金Project supported by the National High Technology Research and Development Program of China(No.2006AA03Z420)the National Natural Science Foundation of China(Nos.60776057,60837001,60776057)
文摘A 16 channel arrayed waveguide grating demultiplexer with 200 GHz channel spacing based on Si nanowire waveguides is designed. The transmission spectra response simulated by transmission function method shows that the device has channel spacing of 1.6 nm and crosstalk of 31 dB. The device is fabricated by 193 nm deep UV lithography in silicon-on-substrate. The demultiplexing characteristics are observed with crosstalk of 5-8 dB, central channel＇s insertion loss of 2.2 dB, flee spectral range of 24.7 nm and average channel spacing of 1.475 nm. The cause of the spectral distortion is analyzed specifically.
基金Project supported by the National High Technology Research and Development Program of China(Grant Nos.2013AA031401,2015AA016902,and 2015AA016904)the National Natural Science Foundation of China(Grant Nos.61176053,61274069,and 61435002)the National Basic Research Program of China(Grant Nos.2012CB933503 and 2013CB932904)
文摘We have provided optical simulations of the evanescently coupled waveguide photodiodes integrated with a 13- channels AWGs. The photodiode could exhibit high internal efficiency by appropriate choice of layers geometry and refrac- tive index. Aseamless joint structure has been designed and fabricated for integrating the output waveguides of AWGs with the evanescently coupled waveguide photodiode array. The highest simulation quantum efficiency could achieve 92% when the matching layer thickfiess of the PD is 120 nm and the insertion length is 2 μm. The fabricated PD with 320-nm-thick match.ing layer and 2-μm-length insertion matching layer present a responsivity of 0.87 A/W.
基金supported by the National Natural Science Foundation of China(No.11254001)the Science and Technology Development of Jilin Province of China(Nos.20110320,201201078)
文摘Based on transmission theory, a 17 x 17 polymer arrayed waveguide grating （AWG） multiplexer para meter optimization is performed, and the influence of the fabrication results on the transmission characteristics are analyzed. In this paper, we mainly discuss three of the main errors in the fabrication of polymer AWG devices. One is 3n 1, which is caused by the tuning of the core refractive index n 1, the second is 8b, which results from the rotating-coating of the core thickness b, and the other is the non-ideal core cross-section, which is caused by steam redissolution. The effects of the above fabrication errors on the transmission characteristics of the AWG device are investigated, and compensation techniques are proposed. By comparing the theoretical simulation and experimental results, the shift in the transmission spectrum is reduced by 0.028 nm, the 3 dB bandwidth is increased by about 0.036 nm, the insertion loss is reduced by about 3 dB for the central channel and 4.5 dB for the edge channels, and the crosstalk is reduced by 1.5 dB.
文摘Integrated spectrometers with both wide optical bandwidths and high spectral resolutions are required in applications such as spectral domain optical coherence tomography(SD-OCT).Here we propose a compact integrated scanning spectrometer by using a tunable micro-ring resonator(MRR)integrated with a single arrayed waveguide grating for operation in the 1265-1335-nm range.The spectral resolution of the spectrometer is determined by the quality factor of the MRR,and the optical bandwidth is defined by the free spectral range of the arrayed waveguide grating.The spectrometer is integrated with on-chip germanium photodetectors,which enable direct electrical readout.A 70-nm optical bandwidth and a 0.2-nm channel spacing enabled by scanning the MRR across one free spectral range are demonstrated,which offer a total of350 wavelength channels with 31-kHz wavelength scanning speed.The integrated spectrometer is applied to measure different spectra and the interference signals from an SD-OCT system,which shows its great potential for future applications in sensing and imaging systems.
基金Project supported by the National Key Research and Development Program of China(Grant No.2016YFB0402504)the National Nature Science Foundation of China(Grant No.61435013)
文摘A 16-channel dual tuning wavelength division multiplexer/demultiplexer based on silicon on insulator platform is demonstrated, which is both peak wavelength tunable and output optical power tunable. The wavelength division multiplexer/demultiplexer consists of an arrayed waveguide grating for wavelength division multiplexing/demultiplexing, a heater for peak wavelength tuning and a variable optical attenuator based on p–i–n carrier-injection structure for optical power tuning. The experimental results show that the insertion loss on chip of the device is 3.7 dB–5.7 dB and the crosstalk is 7.5 dB–9 dB. For the tunability of the peak wavelength, 1.058-nm wavelength tunability is achieved with 271.2-mW power consumption, and the average modulation efficiency is 3.9244 nm/W; for the tunability of the optical power, the optical power equalization is achieved in all 16 channels, 20-dB attenuation is achieved with 144.07-mW power consumption,and the raise/fall time of VOA is 35 ns/42 ns.
文摘One fiber radio scheme using shifted prime codes for interference elimination is proposed for optical code-division multiple-access (OCDMA) network. By taking advantage of the cyclic property of the shifted prime codes in the same code groups, the proposed compact decoder is low cost and suitable to be used in the task manager node in the applications of wireless sensor networks. The performance comparison for sev-eral OCDMA-based fiber radio networks is also given to clarify the advantage of the proposed one.
文摘We proposed an arrayed waveguide granting （AWG） based 10 Gbps full duplex wavelength division multiplexing passive optical network （WDM-PON） utiliz- ing a return-to-zero differential phase shift keying （RZ- DPSK） modulation technique for down-link direction and then re-modulation of the downlink （DL） signal for the uplink （UL） direction using intensity modulation technique （OOK） with a data rate of 10 Gbps per channel. A successful cost effective colorless WDM-PON full duplex transmission operation for a data rate of 10Gbps per channel, with a channel spacing of 60 GHz over a distance of 25 km without any optical amplification and dispersion compensation is achieved within low power penalty.
基金Project supported by the National Natural Science Foundation of China(Nos.61635001 and 61575186)the National High-Tech R&D Program of China(863 Program)(No.2013AA014201)
文摘The design and fabrication of a compact and low-cost 4×25-Gb/s transmitter optical sub-assembly(TOSA) and receiver optical sub-assembly(ROSA) using a hybrid integrated technique are reported. TOSA and ROSA are developed without thermoelectric cooler for coarse wavelength division multiplexing applications. Physical dimension of the packaged optical subassembly is limited to 11.5 mm×5.4 mm×5.4 mm. The design of TOSA and ROSA is employed using a silica-based arrayed waveguide grating chip to select the specific channel wavelength at O-band. In TOSA, the wavelength of four 1.3-μm discrete directly modulated laser chips is well controlled based on the reconstruction equivalent chirp technique. In the back-to-back transmission test, bit error rates for all lanes of cascade of the TOSA and ROSA are small. A clear opening eye diagram is obtained.
基金Project supported by the National High Technology Research and Development Program of China(Grant Nos.2011AA010303 and 2013AA031401)the National Natural Science Foundation of China(Grant No.61090390)
文摘A 13-channel, InP-based arrayed waveguide grating （AWG） is designed and fabricated in which the on-chip loss of the central channel is about -5 dB and the crosstalk is less than -23 dB in the center of the spectrum response. However, the central wavelength and channel spacing are deviated from the design values. To improve their accuracy, an optimized design is adopted to compensate the process error. As a result, the central wavelength 1549.9 nm and channel spacing 1.59 nm are obtained in the experiment, while their design values are 1549.32 nm and 1.6 nm, respectively. The route capability and thermo-optic characteristic of the AWG are also discussed in detail.
文摘An optical network is a type of data communication network built with optical fibre technology. It utilizes optical fibre cables as the primary communication medium for converting data and passing data as light pulses between sender and receiver nodes. The major issue in optical networking is disjoints that occur in the network. A polynomial time algorithm Wavelength Division Multiplexing-Passive Optical Networking (WDM-PON) computes disjoints of an optical network and reduces the count of disjoints that occur in the network by separating Optical Network Units (ONU) into several virtual point-to-point connections. The Arrayed Waveguide Grating (AWG) filter is included in WDM-PON to avoid the traffic in the network thereby increasing the bandwidth capacity. In case of a failure or disjoint Ant Colony Optimization (ACO) algorithm is used to find the optimized shortest path for re-routing. For enhanced security, modified Rivert Shamir Adleman (RSA) algorithm encrypts the message during communication between the nodes. The efficiency is found to be improved in terms of delay in packet delivery, longer optical reach, optimized shortest path, packet error rate.
