针对现有的管道防腐蚀技术涂层材料质量差、预测腐蚀速率精度低等问题,提出了一种外加电流阴极保护(Impressed Current Cathodic Protection,ICCP)系统结构。通过阴极保护(Cathodic Protection,CP)仪表监测管道表面电位,选用超疏水涂层...针对现有的管道防腐蚀技术涂层材料质量差、预测腐蚀速率精度低等问题,提出了一种外加电流阴极保护(Impressed Current Cathodic Protection,ICCP)系统结构。通过阴极保护(Cathodic Protection,CP)仪表监测管道表面电位,选用超疏水涂层作为管道的缓蚀剂。研究基于CenterNet构建深度学习预测模型,通过将正常电位和腐蚀电位视为袋子并将管道表面电位视为袋子中的样本,利用分类中性能指标特征曲线下面积(Area Under Curve,AUC)来预测管道腐蚀情况。结果表明:该预测模型精准度更高,在预测2021年管道的腐蚀速率误差为0%。展开更多
Background： Cirrhosis is a common complication of chronic hepatitis B. It remains unclear if viral and biochemical parameters at baseline affect virological response to entecavir and therefore warrant investigation. ...Background： Cirrhosis is a common complication of chronic hepatitis B. It remains unclear if viral and biochemical parameters at baseline affect virological response to entecavir and therefore warrant investigation. In the present study, we aimed to eval uate the efficacy of entecavir therapy by monitoring virological response at the end of the 3^rd month of treatment and try to figure out whether baseline factors could help predict it in a cohort of hepatitis B virus （HBV） compensated cirrhosis patients and to determine the cut-off value of a predicting parameter.Methods： A total of 91 nucleos（t）ide-naive patients with HBV induced cirrhosis （compensatory stage） were enrolled in a prospective cohort. HBV DNA and alanine aminotransferase （ALT） were tested at baseline and monitored every 3-6 months after starting therapy. Results： Of all 91 patients, the median follow-up time was 12 （9-24） months. Overall, 64 patients （70.3%） achieved virological response in the 3^rd month. Univariate analysis showed that the 3^rd month virological response can be predicted by baseline HBV DNA levels （P 〈 0.001, odds ratio [OR]： 2.13, 95% confidence interval [CI]： 1.44-3.15）, ALT value （P = 0.023, OR： 1.01, 95% CI： 1.00 1.01 ） and hepatitis B e antigen （HBeAg） negativity （P = 0.016, OR： 0.30, 95% CI： 0.11-0.80）. Multiple regression analysis showed baseline H BV DNA level was the only parameter related to full virological response. Higher baseline HBV DNA strata indicated a higher probability that HBV DNA remains detectable at the 3^rd month （P = 0.001）. Area under receiver operating characteristic curve for determining the 3^rd month virological response by baseline HBV DNA was 77.6% （95% CI： 66.7-85.2%）, with a best cut-offvalue of 5.8 log10. Conclusions： Baseline HBV DNA, HBeAg negativity, and ALT were independent factors contributing to virological response at the 3^rt month. Further, multiple regression showed that HBV DNA level was the only parameter predi展开更多
文摘针对现有的管道防腐蚀技术涂层材料质量差、预测腐蚀速率精度低等问题,提出了一种外加电流阴极保护(Impressed Current Cathodic Protection,ICCP)系统结构。通过阴极保护(Cathodic Protection,CP)仪表监测管道表面电位,选用超疏水涂层作为管道的缓蚀剂。研究基于CenterNet构建深度学习预测模型,通过将正常电位和腐蚀电位视为袋子并将管道表面电位视为袋子中的样本,利用分类中性能指标特征曲线下面积(Area Under Curve,AUC)来预测管道腐蚀情况。结果表明:该预测模型精准度更高,在预测2021年管道的腐蚀速率误差为0%。
文摘Background： Cirrhosis is a common complication of chronic hepatitis B. It remains unclear if viral and biochemical parameters at baseline affect virological response to entecavir and therefore warrant investigation. In the present study, we aimed to eval uate the efficacy of entecavir therapy by monitoring virological response at the end of the 3^rd month of treatment and try to figure out whether baseline factors could help predict it in a cohort of hepatitis B virus （HBV） compensated cirrhosis patients and to determine the cut-off value of a predicting parameter.Methods： A total of 91 nucleos（t）ide-naive patients with HBV induced cirrhosis （compensatory stage） were enrolled in a prospective cohort. HBV DNA and alanine aminotransferase （ALT） were tested at baseline and monitored every 3-6 months after starting therapy. Results： Of all 91 patients, the median follow-up time was 12 （9-24） months. Overall, 64 patients （70.3%） achieved virological response in the 3^rd month. Univariate analysis showed that the 3^rd month virological response can be predicted by baseline HBV DNA levels （P 〈 0.001, odds ratio [OR]： 2.13, 95% confidence interval [CI]： 1.44-3.15）, ALT value （P = 0.023, OR： 1.01, 95% CI： 1.00 1.01 ） and hepatitis B e antigen （HBeAg） negativity （P = 0.016, OR： 0.30, 95% CI： 0.11-0.80）. Multiple regression analysis showed baseline H BV DNA level was the only parameter related to full virological response. Higher baseline HBV DNA strata indicated a higher probability that HBV DNA remains detectable at the 3^rd month （P = 0.001）. Area under receiver operating characteristic curve for determining the 3^rd month virological response by baseline HBV DNA was 77.6% （95% CI： 66.7-85.2%）, with a best cut-offvalue of 5.8 log10. Conclusions： Baseline HBV DNA, HBeAg negativity, and ALT were independent factors contributing to virological response at the 3^rt month. Further, multiple regression showed that HBV DNA level was the only parameter predi
