Marine-derived chitosan has been widely examined for its use in developing biomedical materials.Not only is it non-toxic,biocompatible,and degradable,it has also shown unique antimicrobial properties.The antimicrobial...Marine-derived chitosan has been widely examined for its use in developing biomedical materials.Not only is it non-toxic,biocompatible,and degradable,it has also shown unique antimicrobial properties.The antimicrobial properties of chitosan are restricted by neutral and physiological conditions because it is insoluble in water and its pKa values is 6.5.One solution to this problem is to graft chemically modified groups onto the backbone of chitosan.The aim of this paper is to review the mode of antimicrobial action of chitosan and chitosan derivatives.Using chitosan alone may not meet the demands of various applications.However,the introduction of additional polymers and antimicrobial agents is commonly used to enhance the antimicrobial potential of chitosan-based biomaterials.Chitosan-based composite biomaterials have been developed that allow diversified formulations to broaden applications,including nanoparticles,hydrogels,films,sponges,fibers,or even microspheres.These along with recent advances on chitosan-based composite biomaterials used for wound healing,food packaging,textile sector,3D printing and dental materials,were reviewed in detail.展开更多
Antimicrobial-treated textiles should exhibit efficacy against a broad spectrum of bacterial and fungal species,all while maintaining user safety with a non-toxic profile.Natural antimicrobial compounds play a vital r...Antimicrobial-treated textiles should exhibit efficacy against a broad spectrum of bacterial and fungal species,all while maintaining user safety with a non-toxic profile.Natural antimicrobial compounds play a vital role in textile finishing processes.The proliferation of synthetic antimicrobial agents introduces environmental and consumer safety concerns.Given these potential hazards associated with synthetic agents,the utilization of natural antimicrobial agents is gaining traction,as they tend to have fewer adverse effects on users and are more environmentally sustainable.Numerous natural antimicrobial compounds,sourced from plants such as neem,basil,turmeric,aloe vera,and clove oil,have been developed,showcasing inherent antimicrobial properties.This review article highlights the importance of incorporating bioactive components in the creation of antibacterial textile fabrics.展开更多
基金Acknowledgements This work was supported by the National Natural Science Foundation of China(Grant number 31500807)China Postdoctoral Science Foundation Special Funded Project(Grant number 2016T90651)Taishan Scholar Program,China.
文摘Marine-derived chitosan has been widely examined for its use in developing biomedical materials.Not only is it non-toxic,biocompatible,and degradable,it has also shown unique antimicrobial properties.The antimicrobial properties of chitosan are restricted by neutral and physiological conditions because it is insoluble in water and its pKa values is 6.5.One solution to this problem is to graft chemically modified groups onto the backbone of chitosan.The aim of this paper is to review the mode of antimicrobial action of chitosan and chitosan derivatives.Using chitosan alone may not meet the demands of various applications.However,the introduction of additional polymers and antimicrobial agents is commonly used to enhance the antimicrobial potential of chitosan-based biomaterials.Chitosan-based composite biomaterials have been developed that allow diversified formulations to broaden applications,including nanoparticles,hydrogels,films,sponges,fibers,or even microspheres.These along with recent advances on chitosan-based composite biomaterials used for wound healing,food packaging,textile sector,3D printing and dental materials,were reviewed in detail.
文摘Antimicrobial-treated textiles should exhibit efficacy against a broad spectrum of bacterial and fungal species,all while maintaining user safety with a non-toxic profile.Natural antimicrobial compounds play a vital role in textile finishing processes.The proliferation of synthetic antimicrobial agents introduces environmental and consumer safety concerns.Given these potential hazards associated with synthetic agents,the utilization of natural antimicrobial agents is gaining traction,as they tend to have fewer adverse effects on users and are more environmentally sustainable.Numerous natural antimicrobial compounds,sourced from plants such as neem,basil,turmeric,aloe vera,and clove oil,have been developed,showcasing inherent antimicrobial properties.This review article highlights the importance of incorporating bioactive components in the creation of antibacterial textile fabrics.