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“鸡尾酒”式混合抗生素对细菌耐药性的影响 被引量:5
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作者 韩宝苍 陈志彬 +2 位作者 张跃恒 林志芬 孙昊宇 《中国环境科学》 EI CAS CSCD 北大核心 2022年第1期434-443,共10页
选择四环素、磺胺、磺胺增效剂3类常用抗生素,以其对大肠杆菌(E.coli)的单一兴奋效应(hormesis)最大促进效应对应浓度(HC_(max))配制等HC_(max)比的二元及三元混合体系,探究混合体系对细菌生长和耐药性(突变、质粒接合转移)的联合效应.... 选择四环素、磺胺、磺胺增效剂3类常用抗生素,以其对大肠杆菌(E.coli)的单一兴奋效应(hormesis)最大促进效应对应浓度(HC_(max))配制等HC_(max)比的二元及三元混合体系,探究混合体系对细菌生长和耐药性(突变、质粒接合转移)的联合效应.结果表明,二元混合抗生素对E.coli生长和接合转移频率起到协同抑制,对E.coli的突变频率起协同刺激;三元混合抗菌剂对这三种效应均协同抑制.因此,推测二元混合体系会导致毒性和耐药性风险同时增加;三元混合体系会导致毒性风险增加、耐药性风险降低. 展开更多
关键词 混合抗生素 细菌耐药性 HORMESIS 突变 接合转移
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Long-term follow-ups of revascularized immature necrotic teeth:three case reports 被引量:14
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作者 Duck-Su Kim Hae-Jin Park +5 位作者 Je-Ha Yeom Ji-Sung Seo Gil-Joo Ryu Ki-Ho Park Seung-Il Shin Sun-Young Kim 《International Journal of Oral Science》 SCIE CAS CSCD 2012年第2期109-113,共5页
Revascularization of immature necrotic teeth is a reliable treatment alternative to conventional apexogenesis or apexification. In case 1, a 12-year-old boy had his necrotic, immature mandibular left second premolar t... Revascularization of immature necrotic teeth is a reliable treatment alternative to conventional apexogenesis or apexification. In case 1, a 12-year-old boy had his necrotic, immature mandibular left second premolar treated with a revascularization technique. At a 24-month follow-up, periapical radiolucency had disappeared and thickening of the root wall was observed. In cases 2 and 3, a lO-year-old boy had his necrotic, immature, bilateral mandibular second premolars treated with the same modality. At 48-month (in case 2) and 42-month (in case 3) follow-ups, loss of periapical radiolucencies and increases in the root wall thickness were also observed. 展开更多
关键词 REVASCULARIZATION pulp necrosis mineral trioxide aggregate antibiotic mixture immature tooth
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饲料用抗菌与抗寄生虫促生长预混剂的应用与评价(上)
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作者 谢麟 张碧莲 《四川畜牧兽医》 2001年第10期33-34,共2页
介绍供养殖用的抗菌与抗寄生虫药物的饲料预混剂及其选择应用并评价。
关键词 抗菌剂 抗寄生虫剂 饲料预混剂 饲料添加剂
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