A 54-year-old man presented with rectal pain and bleeding secondary to ulcerated,necrotic rectal and cecal masses that resembled colorectal carcinoma upon colonoscopy.These masses were later determined to be benign am...A 54-year-old man presented with rectal pain and bleeding secondary to ulcerated,necrotic rectal and cecal masses that resembled colorectal carcinoma upon colonoscopy.These masses were later determined to be benign amebomas caused by invasive Entamoeba histolytica,which regressed completely with medical therapy.In Western countries,the occurrence of invasive protozoan infection with formation of amebomas is very rare and can mistakenly masquerade as a neoplasm.Not surprisingly,there have been very few cases reported of this clinical entity within the United States.Moreover,we report a patient that had an extremely rare occurrence of two synchronous lesions,one involving the rectum and the other situated in the cecum.We review the current literature on the pathogenesis of invasive E.histolytica infection and ameboma formation,as well as management of this rare disease entity at a western medical center.展开更多
AIM. To assess the causes of ileocecal mass in patients with amebic liver abscess. METHODS： Patients with amebic liver abscess and ileocecal mass were carefully examined and investigated by contrast-enhanced CT scan ...AIM. To assess the causes of ileocecal mass in patients with amebic liver abscess. METHODS： Patients with amebic liver abscess and ileocecal mass were carefully examined and investigated by contrast-enhanced CT scan followed by colonoscopy and histological examination of biopsy materials from lesions during colonoscopy. RESULTS： Ileocecal masses were found in seventeen patients with amebic liver abscess. The cause of the mass was ameboma in 14 patients, cecal tuberculosis in 2 patients and adenocarcinoma of the cecum in 1 patient. Colonic ulcers were noted in five of the six （83%） patients with active diarrhea at presentation. The ileocecal mass in all these patients was ameboma. Ulcers were seen in only one of the 11 （9%） patients without diarrhea. The difference was statistically significant from the group with diarrhea （P〈 0.005）. CONCLUSION： Ileocecal mass is not an uncommon finding in patients with amebic liver abscess. Although, the ileocecal mass is due to ameboma formation in most cases, it should not be assumed that this is the case in all patients. Colonoscopy and histological examination of the target biopsies are mandatory to avoid missing a more sinister lesion.展开更多
文摘A 54-year-old man presented with rectal pain and bleeding secondary to ulcerated,necrotic rectal and cecal masses that resembled colorectal carcinoma upon colonoscopy.These masses were later determined to be benign amebomas caused by invasive Entamoeba histolytica,which regressed completely with medical therapy.In Western countries,the occurrence of invasive protozoan infection with formation of amebomas is very rare and can mistakenly masquerade as a neoplasm.Not surprisingly,there have been very few cases reported of this clinical entity within the United States.Moreover,we report a patient that had an extremely rare occurrence of two synchronous lesions,one involving the rectum and the other situated in the cecum.We review the current literature on the pathogenesis of invasive E.histolytica infection and ameboma formation,as well as management of this rare disease entity at a western medical center.
文摘AIM. To assess the causes of ileocecal mass in patients with amebic liver abscess. METHODS： Patients with amebic liver abscess and ileocecal mass were carefully examined and investigated by contrast-enhanced CT scan followed by colonoscopy and histological examination of biopsy materials from lesions during colonoscopy. RESULTS： Ileocecal masses were found in seventeen patients with amebic liver abscess. The cause of the mass was ameboma in 14 patients, cecal tuberculosis in 2 patients and adenocarcinoma of the cecum in 1 patient. Colonic ulcers were noted in five of the six （83%） patients with active diarrhea at presentation. The ileocecal mass in all these patients was ameboma. Ulcers were seen in only one of the 11 （9%） patients without diarrhea. The difference was statistically significant from the group with diarrhea （P〈 0.005）. CONCLUSION： Ileocecal mass is not an uncommon finding in patients with amebic liver abscess. Although, the ileocecal mass is due to ameboma formation in most cases, it should not be assumed that this is the case in all patients. Colonoscopy and histological examination of the target biopsies are mandatory to avoid missing a more sinister lesion.
