The trifluoromethylthio group （SCF3） is a fluorine chemotype that has experienced a strong acceleration of in- terest in the recent years. It is particularly true of the construction of new fluorinated architectures...The trifluoromethylthio group （SCF3） is a fluorine chemotype that has experienced a strong acceleration of in- terest in the recent years. It is particularly true of the construction of new fluorinated architectures by electrophilic trifluoromethylthiolation. The spread of knowledge was already very active in this research domain in the sixties; however, gaseous and highly toxic trifluoromethanesulfenyl chloride （CF3SC1） was the only reagent available at that time. Nowadays, one really can speak of a revival in the field thanks to the rapid development of a wide pano- ply of reagents that are stable and easy to handle. This review provides a historical perspective of the development of shelf-stable electrophilic trifluoromethylthiolation reagents.展开更多
With the rapid advancement of Internet technology,cyberspace has emerged as an indispensable component of modern society,profoundly altering the lifestyles,work patterns,and social interactions of Chinese college stud...With the rapid advancement of Internet technology,cyberspace has emerged as an indispensable component of modern society,profoundly altering the lifestyles,work patterns,and social interactions of Chinese college students.However,according to scholarly investigations,there exists an issue of excessive dependency on cyberspace and cyber addition among this group.This study investigated the intensity of cyber addition and associated psychological concerns among Chinese college students,employing a mixed-methods research design that integrated both questionnaire surveys and interviews.The findings revealed that Chinese college students exhibited a moderate level of cyber addition,particularly in terms of psychological dimensions where the intensity was higher.Conversely,the intensity of cyber addition was relatively lower in terms of socialization.Interviews further substantiated the survey results,shedding light on the students’complex attitudes and concerns regarding cyber addition.This study serves to enhance awareness among both students and educators regarding the problem of cyber addition and provides a scientific basis for formulating effective intervention strategies.展开更多
The intramolecular cyclization of 2-alkynylanilines mediated by DMSO/SOCI_(2) was found to afford biologically interesting 3-methylthioindoles,which are rarely obtained by the exiting methods.DMSO could also be replac...The intramolecular cyclization of 2-alkynylanilines mediated by DMSO/SOCI_(2) was found to afford biologically interesting 3-methylthioindoles,which are rarely obtained by the exiting methods.DMSO could also be replaced with its deuterated counterpart,enabling the method applicable to the construction of indole skeleton bearing a SCD_(3) moiety at its 3-position.展开更多
Effects of antibiotic residues on methane production in anaerobic digestion are commonly studied using the following two antibiotic addition methods：（1） adding manure from animals that consume a diet containing ant...Effects of antibiotic residues on methane production in anaerobic digestion are commonly studied using the following two antibiotic addition methods：（1） adding manure from animals that consume a diet containing antibiotics, and（2） adding antibiotic-free animal manure spiked with antibiotics. This study used chlortetracycline（CTC） as a model antibiotic to examine the effects of the antibiotic addition method on methane production in anaerobic digestion under two different swine wastewater concentrations（0.55 and 0.22 mg CTC/g dry manure）. The results showed that CTC degradation rate in which manure was directly added at 0.55 mg CTC/g（HSPIKE treatment） was lower than the control values and the rest of the treatment groups. Methane production from the HSPIKEtreatment was reduced（p 〈 0.05） by 12% during the whole experimental period and 15% during the first 7 days. The treatments had no significant effect on the pH and chemical oxygen demand value of the digesters, and the total nitrogen of the0.55 mg CTC/kg manure collected from mediated swine was significantly higher than the other values. Therefore, different methane production under different antibiotic addition methods might be explained by the microbial activity and the concentrations of antibiotic intermediate products and metabolites. Because the primary entry route of veterinary antibiotics into an anaerobic digester is by contaminated animal manure, the most appropriate method for studying antibiotic residue effects on methane production may be using manure from animals that are given a particular antibiotic, rather than adding the antibiotic directly to the anaerobic digester.展开更多
文摘The trifluoromethylthio group （SCF3） is a fluorine chemotype that has experienced a strong acceleration of in- terest in the recent years. It is particularly true of the construction of new fluorinated architectures by electrophilic trifluoromethylthiolation. The spread of knowledge was already very active in this research domain in the sixties; however, gaseous and highly toxic trifluoromethanesulfenyl chloride （CF3SC1） was the only reagent available at that time. Nowadays, one really can speak of a revival in the field thanks to the rapid development of a wide pano- ply of reagents that are stable and easy to handle. This review provides a historical perspective of the development of shelf-stable electrophilic trifluoromethylthiolation reagents.
基金This research was supported by the Guangdong Province 2021th Educational Science planning program“Morality Education Special”(Project number:2021JKDY071).
文摘With the rapid advancement of Internet technology,cyberspace has emerged as an indispensable component of modern society,profoundly altering the lifestyles,work patterns,and social interactions of Chinese college students.However,according to scholarly investigations,there exists an issue of excessive dependency on cyberspace and cyber addition among this group.This study investigated the intensity of cyber addition and associated psychological concerns among Chinese college students,employing a mixed-methods research design that integrated both questionnaire surveys and interviews.The findings revealed that Chinese college students exhibited a moderate level of cyber addition,particularly in terms of psychological dimensions where the intensity was higher.Conversely,the intensity of cyber addition was relatively lower in terms of socialization.Interviews further substantiated the survey results,shedding light on the students’complex attitudes and concerns regarding cyber addition.This study serves to enhance awareness among both students and educators regarding the problem of cyber addition and provides a scientific basis for formulating effective intervention strategies.
基金the National Natural Science Foundation of China(No.22071175)K.Zhao acknowledges the National Key R&D Program of China(No.2019YFA0905104)for financial supports.
文摘The intramolecular cyclization of 2-alkynylanilines mediated by DMSO/SOCI_(2) was found to afford biologically interesting 3-methylthioindoles,which are rarely obtained by the exiting methods.DMSO could also be replaced with its deuterated counterpart,enabling the method applicable to the construction of indole skeleton bearing a SCD_(3) moiety at its 3-position.
基金supported by the National Natural Science Foundation of China (Nos. 30700586, 31072067, 31272481)the National Spark Program Project (No. 2012GA780001)the China Scholarship Council (NO. 201308440210)
文摘Effects of antibiotic residues on methane production in anaerobic digestion are commonly studied using the following two antibiotic addition methods：（1） adding manure from animals that consume a diet containing antibiotics, and（2） adding antibiotic-free animal manure spiked with antibiotics. This study used chlortetracycline（CTC） as a model antibiotic to examine the effects of the antibiotic addition method on methane production in anaerobic digestion under two different swine wastewater concentrations（0.55 and 0.22 mg CTC/g dry manure）. The results showed that CTC degradation rate in which manure was directly added at 0.55 mg CTC/g（HSPIKE treatment） was lower than the control values and the rest of the treatment groups. Methane production from the HSPIKEtreatment was reduced（p 〈 0.05） by 12% during the whole experimental period and 15% during the first 7 days. The treatments had no significant effect on the pH and chemical oxygen demand value of the digesters, and the total nitrogen of the0.55 mg CTC/kg manure collected from mediated swine was significantly higher than the other values. Therefore, different methane production under different antibiotic addition methods might be explained by the microbial activity and the concentrations of antibiotic intermediate products and metabolites. Because the primary entry route of veterinary antibiotics into an anaerobic digester is by contaminated animal manure, the most appropriate method for studying antibiotic residue effects on methane production may be using manure from animals that are given a particular antibiotic, rather than adding the antibiotic directly to the anaerobic digester.
