As a key biomarker for noninvasive diagnosis of diabetes,the selective detection of trace acetone in exhaled gas using a portable and low-cost device remains a great challenge.Semiconductor metal oxide(SMO)based gas s...As a key biomarker for noninvasive diagnosis of diabetes,the selective detection of trace acetone in exhaled gas using a portable and low-cost device remains a great challenge.Semiconductor metal oxide(SMO)based gas sensors have drawn signification attention due to their potential in miniaturization,user-friendliness,high cost-effectiveness and selective real-time detection for noninvasive clinical diagnosis.Herein,we propose a one-pot solvent evaporation induced tricomponent co-assembly strategy to design a novel ordered mesoporous SMO of silica-implanted WO_(3)(Si O_(2)/WO_(3))as sensing materials for trace acetone detection.The controlled co-assembly of silicon and tungsten precursors and amphiphilic diblock copolymer poly(ethylene oxide)-block-polystyrene(PEO-b-PS),and the subsequent thermal treatment enable the local lattice disorder of WO_(3)induced by the amorphous silica and the formation of ordered mesoporous Si O_(2)/WO_(3)hybrid walls with a unique metastableε-phase WO_(3)framework.The obtained mesoporous SiO_(2)/WO_(3)composites possess highly crystalline framework with large uniform pore size(12.0-13.3 nm),high surface area(99-113 m^(2)/g)and pore volume(0.17-0.23 cm^(3)/g).Typically,the asfabricated gas sensor based on mesoporous 2.5%Si O_(2)/WO_(3)exhibits rapid response/recovery rate(5/17 s),superior sensitivity(R_(air)/R_(gas)=105 for 50 ppm acetone),as well as high selectivity towards acetone.The limit of detection is as low as 0.25 ppm,which is considerably lower than the thresh value of acetone concentration(>1.1 ppm)in the exhaled breath of diabetic patients,demonstrating its great prospect in real-time monitoring in diabetes diagnosis.Moreover,the mesoporous 2.5%Si O_(2)/WO_(3)sensor is integrated into a wireless sensing module connected to a smart phone,providing a convenient real-time detection of acetone.展开更多
Solvothermal reaction of imidazolyl-based synthon with deprotonated adipic acid produced a new coordination complex {[Zn（BIDPE）(hdc)]·2 H;O}n（1）. The structure was characterized by single-crystal X-ray crysta...Solvothermal reaction of imidazolyl-based synthon with deprotonated adipic acid produced a new coordination complex {[Zn（BIDPE）(hdc)]·2 H;O}n（1）. The structure was characterized by single-crystal X-ray crystallography. It crystallizes in monoclinic, space group C2/m, at 293 K: a = 12.005（2）, b = 17.956（3）, c = 12.039（2） ?, β = 113.089（3）°, V = 2387.3（7） ?;, Z = 4, Dc = 1.524 g·cm-3, μ（Mo Ka） = 1.082 mm–1 and F（000） = 1136. 5942 reflections were measured and 2180 independent reflections（Rint = 0.0679） were used in further refinement. Complex 1 reveals 1D double-stranded chains containing [Zn;（BIDPE）;] and [Zn;（hdc）;] metallocyclic rings. The adjacent chains are linked by H-bonding and π···π interactions to form a 3D network. Thermal stability and luminescence property were studied. Interestingly, the luminescent emission of 1 can be quenched by the addition of trace amount of acetone, demonstrating its potential application for sensitive detecting acetone.展开更多
基金financially supported by National Natural Science Foundation of China(Nos.62104045,22125501,U22A20152)State Key Laboratory of Transducer Technology of China(No.SKT2207)+1 种基金Medical Engineering Jiont Fund of Fudan University(No.yg2023-10)Fundamental Research Funds for the Central Universities(No.20720220010)。
文摘As a key biomarker for noninvasive diagnosis of diabetes,the selective detection of trace acetone in exhaled gas using a portable and low-cost device remains a great challenge.Semiconductor metal oxide(SMO)based gas sensors have drawn signification attention due to their potential in miniaturization,user-friendliness,high cost-effectiveness and selective real-time detection for noninvasive clinical diagnosis.Herein,we propose a one-pot solvent evaporation induced tricomponent co-assembly strategy to design a novel ordered mesoporous SMO of silica-implanted WO_(3)(Si O_(2)/WO_(3))as sensing materials for trace acetone detection.The controlled co-assembly of silicon and tungsten precursors and amphiphilic diblock copolymer poly(ethylene oxide)-block-polystyrene(PEO-b-PS),and the subsequent thermal treatment enable the local lattice disorder of WO_(3)induced by the amorphous silica and the formation of ordered mesoporous Si O_(2)/WO_(3)hybrid walls with a unique metastableε-phase WO_(3)framework.The obtained mesoporous SiO_(2)/WO_(3)composites possess highly crystalline framework with large uniform pore size(12.0-13.3 nm),high surface area(99-113 m^(2)/g)and pore volume(0.17-0.23 cm^(3)/g).Typically,the asfabricated gas sensor based on mesoporous 2.5%Si O_(2)/WO_(3)exhibits rapid response/recovery rate(5/17 s),superior sensitivity(R_(air)/R_(gas)=105 for 50 ppm acetone),as well as high selectivity towards acetone.The limit of detection is as low as 0.25 ppm,which is considerably lower than the thresh value of acetone concentration(>1.1 ppm)in the exhaled breath of diabetic patients,demonstrating its great prospect in real-time monitoring in diabetes diagnosis.Moreover,the mesoporous 2.5%Si O_(2)/WO_(3)sensor is integrated into a wireless sensing module connected to a smart phone,providing a convenient real-time detection of acetone.
基金supported by the National Natural Science Foundation of China(No.21671004,51404006)
文摘Solvothermal reaction of imidazolyl-based synthon with deprotonated adipic acid produced a new coordination complex {[Zn（BIDPE）(hdc)]·2 H;O}n（1）. The structure was characterized by single-crystal X-ray crystallography. It crystallizes in monoclinic, space group C2/m, at 293 K: a = 12.005（2）, b = 17.956（3）, c = 12.039（2） ?, β = 113.089（3）°, V = 2387.3（7） ?;, Z = 4, Dc = 1.524 g·cm-3, μ（Mo Ka） = 1.082 mm–1 and F（000） = 1136. 5942 reflections were measured and 2180 independent reflections（Rint = 0.0679） were used in further refinement. Complex 1 reveals 1D double-stranded chains containing [Zn;（BIDPE）;] and [Zn;（hdc）;] metallocyclic rings. The adjacent chains are linked by H-bonding and π···π interactions to form a 3D network. Thermal stability and luminescence property were studied. Interestingly, the luminescent emission of 1 can be quenched by the addition of trace amount of acetone, demonstrating its potential application for sensitive detecting acetone.
