A synthetic method of dialkylideneacetones has been developed. Compared with known protocols, the method employed catalytic Ca(OH)_2 as the cheap, mild base catalyst and dilute aqueous EtOH(20%, v/v)as the green and s...A synthetic method of dialkylideneacetones has been developed. Compared with known protocols, the method employed catalytic Ca(OH)_2 as the cheap, mild base catalyst and dilute aqueous EtOH(20%, v/v)as the green and safe solvent. The procedure was easily operated: In most cases, the product could be isolated by a simple filtration, and purified by washing with water. This paper provided experimental details of the reactions, which could be applied in gram-scale synthesis and should be a very reliable and practical protocol to prepare these useful compounds in laboratory and at the industrial level.展开更多
基金the National Natural Science Foundation of China (Nos. 21202141, 21672163)Priority Academic Program Development of Jiangsu Higher Education Institutions (PAPD)+3 种基金Top-notch Academic Programs Project of Jiangsu Higher Education Institutions (TAPP)the high level talent support project of Yangzhou University (top-notch talent, L. Yu)Yangzhou Natural Science Foundation (No. YZ2014040)the Natural Science Foundation of Guangling College (No. ZKZD17005) for financial support
文摘A synthetic method of dialkylideneacetones has been developed. Compared with known protocols, the method employed catalytic Ca(OH)_2 as the cheap, mild base catalyst and dilute aqueous EtOH(20%, v/v)as the green and safe solvent. The procedure was easily operated: In most cases, the product could be isolated by a simple filtration, and purified by washing with water. This paper provided experimental details of the reactions, which could be applied in gram-scale synthesis and should be a very reliable and practical protocol to prepare these useful compounds in laboratory and at the industrial level.
