Hepatocellular carcinoma (HCC) is a cancer with increasing incidence in the USA and high mortality rate. HCC is often difficult to treat due to underlying comorbidities such as cirrhosis. However, the application of l...Hepatocellular carcinoma (HCC) is a cancer with increasing incidence in the USA and high mortality rate. HCC is often difficult to treat due to underlying comorbidities such as cirrhosis. However, the application of loco-regional thermal ablation using radio frequency (RF) and trans-arterial embolization with chemotherapy (TACE) or without (TAE) has shown promising results in the treatment of patients not amenable to surgical resection or liver transplantation. Conventionally, RF and TAE are performed in two separated sessions or two steps and often RF ablation is performed percutaneously. However, no consensus has been reached regarding the ideal interval between the two treatments. In this article, we discuss the feasibility and benefits of a single-step TAE in combination with laparoscopic RF ablation in one operative session. We also present a case where this procedure has been successfully performed demonstrating its feasibility. We suggest that the use of laparoscopic RF ablation in the same surgical session as TAE is feasible and potentially offers several advantages over the two-step process that is usually performed with embolization followed by percutaneous RF with a long time interval. In this article we discuss such advantages.展开更多
Scientific research involving nanotechnology has grown exponentially and has led to the development of engineered nanoparticles（NPs）.Silica NPs have been used in numerous scientific and technological applications ov...Scientific research involving nanotechnology has grown exponentially and has led to the development of engineered nanoparticles（NPs）.Silica NPs have been used in numerous scientific and technological applications over the past decade,necessitating the development of efficient methods for their synthesis.Recent studies have explored the potential of laser ablation as a convenient way to prepare metal and oxide NPs.Due to its high silica content,low cost,and widespread availability,sugarbeet bagasse is highly suitable as a raw material for producing silica NPs via laser ablation.In this study,two different NP production methods were investigated：laser ablation and NaOH treatment.We developed a novel,one-step method to produce silica NPs from sugarbeet bagasse using laser ablation,and we characterized the silica NPs using environmental scanning electron microscopy（ESEM）,energy dispersive spectrometry（EDS）,dynamic light scattering（DLS）,transmission electron microscopy（TEM）,attenuated total reflectanceFourier transform infrared spectroscopy（ATR-FT1R）,X-ray photoelectron spectroscopy（XPS） and Raman spectroscopy.EDS analysis and XPS confirmed the presence of silica NPs.The NPs produced by laser ablation were smaller（38-190 nm） than those produced by NaOH treatment（531-825 nm）.Finally,we demonstrated positive effects of silica NPs produced from laser ablation on the growth of microalgae,and thus,our novel method may be beneficial as an environmentally friendly procedure to produce NPs.展开更多
This work reports a one-pot procedure of laser ablation on a graphite target in a liquid medium, based on the variation of different parameters such as target type, laser wavelength, and ablation medium,to obtain high...This work reports a one-pot procedure of laser ablation on a graphite target in a liquid medium, based on the variation of different parameters such as target type, laser wavelength, and ablation medium,to obtain high-quality graphene nanosheets. The morphology of derived products was characterized by the field emission scanning electron microscopy(FE-SEM). Then, the morphology and structure of the optimized sample were characterized by transmission electron microscopy(TEM), X-ray diffraction(XRD), ultraviolet-visible-near infrared(UV–vis-NIR) spectroscopy, Raman spectroscopy, and X-ray photoelectron spectroscopy(XPS). By controlling the laser ablation parameters, we were able to prepare micrometer-sized few-layer graphene nanosheets with mainly less than ten layers. Such synthesized graphene nanosheets were grown at the surface of a flexible graphite target, indicating many potential applications in fundamental research, electrochemical and as hydrophobic surfaces.展开更多
文摘Hepatocellular carcinoma (HCC) is a cancer with increasing incidence in the USA and high mortality rate. HCC is often difficult to treat due to underlying comorbidities such as cirrhosis. However, the application of loco-regional thermal ablation using radio frequency (RF) and trans-arterial embolization with chemotherapy (TACE) or without (TAE) has shown promising results in the treatment of patients not amenable to surgical resection or liver transplantation. Conventionally, RF and TAE are performed in two separated sessions or two steps and often RF ablation is performed percutaneously. However, no consensus has been reached regarding the ideal interval between the two treatments. In this article, we discuss the feasibility and benefits of a single-step TAE in combination with laparoscopic RF ablation in one operative session. We also present a case where this procedure has been successfully performed demonstrating its feasibility. We suggest that the use of laparoscopic RF ablation in the same surgical session as TAE is feasible and potentially offers several advantages over the two-step process that is usually performed with embolization followed by percutaneous RF with a long time interval. In this article we discuss such advantages.
文摘Scientific research involving nanotechnology has grown exponentially and has led to the development of engineered nanoparticles（NPs）.Silica NPs have been used in numerous scientific and technological applications over the past decade,necessitating the development of efficient methods for their synthesis.Recent studies have explored the potential of laser ablation as a convenient way to prepare metal and oxide NPs.Due to its high silica content,low cost,and widespread availability,sugarbeet bagasse is highly suitable as a raw material for producing silica NPs via laser ablation.In this study,two different NP production methods were investigated：laser ablation and NaOH treatment.We developed a novel,one-step method to produce silica NPs from sugarbeet bagasse using laser ablation,and we characterized the silica NPs using environmental scanning electron microscopy（ESEM）,energy dispersive spectrometry（EDS）,dynamic light scattering（DLS）,transmission electron microscopy（TEM）,attenuated total reflectanceFourier transform infrared spectroscopy（ATR-FT1R）,X-ray photoelectron spectroscopy（XPS） and Raman spectroscopy.EDS analysis and XPS confirmed the presence of silica NPs.The NPs produced by laser ablation were smaller（38-190 nm） than those produced by NaOH treatment（531-825 nm）.Finally,we demonstrated positive effects of silica NPs produced from laser ablation on the growth of microalgae,and thus,our novel method may be beneficial as an environmentally friendly procedure to produce NPs.
基金supported financially by the Iran Nanotechnology Initiative Council (INIC) for experimental setup
文摘This work reports a one-pot procedure of laser ablation on a graphite target in a liquid medium, based on the variation of different parameters such as target type, laser wavelength, and ablation medium,to obtain high-quality graphene nanosheets. The morphology of derived products was characterized by the field emission scanning electron microscopy(FE-SEM). Then, the morphology and structure of the optimized sample were characterized by transmission electron microscopy(TEM), X-ray diffraction(XRD), ultraviolet-visible-near infrared(UV–vis-NIR) spectroscopy, Raman spectroscopy, and X-ray photoelectron spectroscopy(XPS). By controlling the laser ablation parameters, we were able to prepare micrometer-sized few-layer graphene nanosheets with mainly less than ten layers. Such synthesized graphene nanosheets were grown at the surface of a flexible graphite target, indicating many potential applications in fundamental research, electrochemical and as hydrophobic surfaces.
