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钼与钼合金的应用及其加工方法 被引量:29
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作者 钟培全 《中国钼业》 2000年第5期15-16,共2页
介绍了钼与钼合金的应用及其加工方法。
关键词 钼合金 加工方法 热加工模具 熔融金属加工
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Microstructure and Properties of Hot Working Die Steel H13MOD 被引量:28
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作者 ZHOU Jian MA Dang-shen +2 位作者 CHI Hong-xiao CHEN Zai-zhi LI Xiang-yang 《Journal of Iron and Steel Research International》 SCIE EI CAS CSCD 2013年第9期117-125,共9页
Compared with H13 steel, the influences of different heat treatment process on the microstructure and properties of the new type of hot working die steel H13MOD were studied. The results show that the complete aus ten... Compared with H13 steel, the influences of different heat treatment process on the microstructure and properties of the new type of hot working die steel H13MOD were studied. The results show that the complete aus tenitizing temperature of H13MOD is around 1030 ℃ and the quenching hardness achieves the maximum value at this temperature. While for H13, the complete austenitizing temperature is above 1100 ℃ and the quenching hardness rise constantly with the quenching temperature increasing. In quenching process, the undissolved MC carbides can prevent the coarsening of grain in both steels. With the rise of quenching temperature, when MC carbides dissolve completely, the grain grows quickly. The hardness and strength of H13MOD at higher tempering temperature (above 570 ℃) are nearly the same as those of H13, but its toughness is higher than that of H13. Mo2C carbide is the main strengthening phase in H13MOD, which is attributed to the higher content of Mo. The quantity of VC eutectic car- bides is reduced because of lower content of V in H13MOD, which plays an important role in enhancing the impact toughness of H13MOD. Under a certain strength condition, H13MOD steel can be used in the environment that higher toughness is required and the service life of die casting mold can be improved. 展开更多
关键词 hot working die steel HARDNESS heat treatment impact ductility tensile strength
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论音乐治疗的基本方法及其操作 被引量:29
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作者 侯艳 《黄钟(武汉音乐学院学报)》 CSSCI 北大核心 2013年第2期167-172,共6页
心理健康日益引起人们的重视,音乐治疗以其疗效独特,当当今也越来越多受到人们的关注。常用的音乐治疗方法有"接受式音乐治疗"、"再创造式音乐治疗"以及"即兴演奏式音乐治疗",这些方法各具特点,根据治疗... 心理健康日益引起人们的重视,音乐治疗以其疗效独特,当当今也越来越多受到人们的关注。常用的音乐治疗方法有"接受式音乐治疗"、"再创造式音乐治疗"以及"即兴演奏式音乐治疗",这些方法各具特点,根据治疗对象以及具体情况的不同,可采用不同的方法进行操作。 展开更多
关键词 音乐治疗 基本方法 操作
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心血管专业临床药师工作模式探讨 被引量:28
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作者 杨勇 唐兵 +2 位作者 王友群 景莉 曾仁杰 《中国药房》 CAS CSCD 北大核心 2008年第4期309-311,共3页
目的:探索一种适合心血管专业临床药师在临床工作中切实可行的模式。方法:通过亲身实践,结合心血管疾病的临床特点和开展临床药学工作的体会进行分析总结。结果与结论:通过"4R"药学查房法,为护士和进修、实习医师提供药学服务... 目的:探索一种适合心血管专业临床药师在临床工作中切实可行的模式。方法:通过亲身实践,结合心血管疾病的临床特点和开展临床药学工作的体会进行分析总结。结果与结论:通过"4R"药学查房法,为护士和进修、实习医师提供药学服务,参与制定复杂患者用药方案等工作,有利于心血管专业临床药师尽快适应临床工作,尽早成为临床治疗团队中的一员。 展开更多
关键词 心血管 临床药师 工作 模式
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Study on real working performance and overload safety factor of high arch dam 被引量:26
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作者 ZHANG GuoXin,LIU Yi & ZHOU QiuJing Department of Structures and Materials,China Institute of Water Resources and Hydropower Research,Beijing 100038,China 《Science China(Technological Sciences)》 SCIE EI CAS 2008年第S2期48-59,共12页
Considering the fact that high arch dams have problems such as complicated stress,high cost,and hazards after being damaged,this paper intends to study the effects of load,material strength,and safety analysis method ... Considering the fact that high arch dams have problems such as complicated stress,high cost,and hazards after being damaged,this paper intends to study the effects of load,material strength,and safety analysis method on dam safety and working performance of arch dams.In this article,the effects of temperature,self weight exaction way and water loading on structure response are first discussed,and a more reasonable way of considering is then put forward.By taking into consideration the mechanical property of materials and comparing the effects of different yield criteria on overloading safety of high arch dams,this paper concludes that brittle characteristics of concrete should be fully considered when conducting safety assessment for high arch dams to avoid overestimating the bearing capacity of the dams.By comparing several typical projects,this paper works out a safety assessment system of multiple safety and relevant engineering analogical analysis methods,which is closer to the actual situation,and thus is able to assess the response of high arch dam structure in a more comprehensive way,elicit the safety coefficients in different situations,and provide a new way of considering the safety assessment of high arch dams. 展开更多
关键词 high ARCH DAM REAL working performance SAFETY LOAD strength SAFETY assessment method
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A forecasting and forewarning model for methane hazard in working face of coal mine based on LS-SVM 被引量:27
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作者 CAO Shu-gang LIU Yan-bao WANG Yan-ping 《Journal of China University of Mining and Technology》 EI 2008年第2期172-176,共5页
To improve the precision and reliability in predicting methane hazard in working face of coal mine, we have proposed a forecasting and forewarning model for methane hazard based on the least square support vector (LS-... To improve the precision and reliability in predicting methane hazard in working face of coal mine, we have proposed a forecasting and forewarning model for methane hazard based on the least square support vector (LS-SVM) multi-classifier and regression machine. For the forecasting model, the methane concentration can be considered as a nonlinear time series and the time series analysis method is adopted to predict the change in methane concentration using LS-SVM regression. For the forewarning model, which is based on the forecasting results, by the multi-classification method of LS-SVM, the methane hazard was identified to four grades: normal, attention, warning and danger. According to the forewarning results, corresponding measures are taken. The model was used to forecast and forewarn the K9 working face. The results obtained by LS-SVM regression show that the forecast- ing have a high precision and forewarning results based on a LS-SVM multi-classifier are credible. Therefore, it is an effective model building method for continuous prediction of methane concentration and hazard forewarning in working face. 展开更多
关键词 working face methane concentration LS-SVM forecasting forewarning
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A New Kind of Pilot Controlled Proportional Direction Valve with Internal Flow Feedback 被引量:25
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作者 QUAN Long XU Xiaoqing YAN Zheng ZHANG Xiaojun 《Chinese Journal of Mechanical Engineering》 SCIE EI CAS CSCD 2010年第1期60-65,共6页
Proportional direction valve is one of the most fundamental elements in electronic-hydraulic control technique. Its function is to control the operating speed, direction, position, and strength of output force of the ... Proportional direction valve is one of the most fundamental elements in electronic-hydraulic control technique. Its function is to control the operating speed, direction, position, and strength of output force of the hydraulic actuator continuously. Considering the different application and the cost, the existing technique mainly includes the internal feedback valve used in open loop system, and the electronic closed loop controlled valve used in closed loop system. Because of their different mechanical structure and the gre at different in performance, it brings inconvenience for customer to select, also inconvenience for enterprise to produce. Aiming at this problem, the idea of combining the above two kinds of valves into one body is proposed first, and then the new valve's structure to realize this target is designed. The idea intends to apply the displacement pilot flow feedback control principle in present 2-position 2-way valve system to the proportional direction valve of 3-position 4-way system. Newly designed feed forward controller can decouple the interference between the internal feedback and the electronic closed loop. Redundant conversion is designed to electronic switch mode. Experiment on dynamic and static characteristic of new proportional direction valve in internal feedback control mode and electronic closed loop control mode is discussed to prove the new theory is correct. Although the new valve is of excellent dynamic response characteristic, its steady control characteristic in open loop control mode needs to be improved further. The research results prepare one new fundamental element for electronic-hydraulic control technology. 展开更多
关键词 pilot flow feedback proportional direction valve working principle characteristic research
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让基层治理有效地运行起来:基于社区的治理 被引量:21
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作者 郎友兴 葛俊良 《浙江社会科学》 CSSCI 北大核心 2014年第7期63-69,157,共7页
社区是基层治理结构变革的基石,某种意义上说,社区治理就是基层治理,基层社会治理需要回到社区的层面。文章讨论了社区治理逻辑问题,提出了社区自主性及社区民主是社区治理的逻辑起点,而社区价值、社区能力和社区社会资本则是社区治理... 社区是基层治理结构变革的基石,某种意义上说,社区治理就是基层治理,基层社会治理需要回到社区的层面。文章讨论了社区治理逻辑问题,提出了社区自主性及社区民主是社区治理的逻辑起点,而社区价值、社区能力和社区社会资本则是社区治理运行的基本要素,在此基础上,作者分析了由居民、社会组织和政府(或其代理者)三者所组成的基层治理体系。文章最后分析了回到社区层面的基层治理,需要对不同类型的社区采取分类治理,选择服务进社区、管理下移、组织重塑的治理路径,在政策面、管理层、法制面进行。 展开更多
关键词 社区 基层治理 社区治理 运行
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THE M/M/1 QUEUE WITH WORKING VACATIONS AND VACATION INTERRUPTIONS 被引量:18
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作者 Jihong LI Naishuo TIAN 《Journal of Systems Science and Systems Engineering》 SCIE EI CSCD 2007年第1期121-127,共7页
In this paper, we study the M/M/1 queue with working vacations and vacation interruptions. The working vacation is introduced recently, during which the server can still provide service on the original ongoing work at... In this paper, we study the M/M/1 queue with working vacations and vacation interruptions. The working vacation is introduced recently, during which the server can still provide service on the original ongoing work at a lower rate. Meanwhile, we introduce a new policy:, the server can come back from the vacation to the normal working level once some indices of the system, such as the number of customers, achieve a certain value in the vacation period. The server may come back from the vacation without completing the vacation. Such policy is called vacation interruption. We connect the above mentioned two policies and assume that if there are customers in the system after a service completion during the vacation period, the server will come back to the normal working level. In terms of the quasi birth and death process and matrix-geometric solution method, we obtain the distributions and the stochastic decomposition structures for the number of customers and the waiting time and provide some indices of systems. 展开更多
关键词 working vacation vacation interruption matrix-geometric solution stochastic decomposition
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Simulation of influence of multi-defects on long-term working performance of high arch dam 被引量:17
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作者 ZHANG GuoXin ,LIU Yi,ZHENG CuiYing & FENG Fan State Key Laboratory of Simulation and Regulation of Water Cycle in River Basin,Beijing 100038,China China Institute of Water Resources and Hydropower Research,Beijing 100038,China 《Science China(Technological Sciences)》 SCIE EI CAS 2011年第S1期1-8,共8页
As an integrated structure,an arch dam is assumed to bear loads in its design consideration.However,multi-defects,such as cracks and the opening of transverse joints,are unavoidable during construction and operation.M... As an integrated structure,an arch dam is assumed to bear loads in its design consideration.However,multi-defects,such as cracks and the opening of transverse joints,are unavoidable during construction and operation.Multi-defects will reduce the structural integrity and stiffness of the dam and affect its working performance and degree of safety.In the current paper,a numerical model of defects and a simulation method of a high arch dam are introduced.The Chencun arch dam is analyzed as a case study.An entire course simulation analysis of the Chencun arch dam from construction to operation is carried out,through which the opening of the transverse and longitudinal joints,formation of cracks,and their influence on deformation and stress of the dam are studied.According to the results of the analysis,appropriate measures should be adopted to prevent the development of cracks,and observation should be strengthened for a more timely discovery of risks. 展开更多
关键词 high ARCH DAM CRACK multi-defects working performance
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Numerical simulation of the factors influencing dust in drilling tunnels:Its application 被引量:17
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作者 Niu Wei Jiang Zhongan Tian Dongmei 《Mining Science and Technology》 EI CAS 2011年第1期11-15,共5页
Gas-solid two-phase flow theory was used to predict dust distribution and movement at the working face of a mine.The software package FLUENT was used to numerically simulate dust motion and the results were compared t... Gas-solid two-phase flow theory was used to predict dust distribution and movement at the working face of a mine.The software package FLUENT was used to numerically simulate dust motion and the results were compared to observed data.The simulation agrees with the data taken from an actual working face,which confirms the choice of mathematical model and numerical simulation method. Using the model we predict a set of conditions optimum for reducing dust concentrations at the mine working face. 展开更多
关键词 Drivage working faceDust concentrationThe gas-solid two-phase flowVentilation method
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阴升阳降是达到阴平阳秘的必然运行形式 被引量:16
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作者 张永康 曹方 乔荣跃 《中华中医药杂志》 CAS CSCD 北大核心 2016年第12期4902-4904,共3页
"阴阳者,天地之道也,万物之纲纪,变化之父母,生杀之本始,神明之府也"。阴阳乃万物之根本,阳升阴降,阴升阳降方可达到阴阳平衡。文章分别从天地阴阳、人体气血、易经卦象、脏腑经络等方面阐述"阴升阳降"理论,从济卦... "阴阳者,天地之道也,万物之纲纪,变化之父母,生杀之本始,神明之府也"。阴阳乃万物之根本,阳升阴降,阴升阳降方可达到阴阳平衡。文章分别从天地阴阳、人体气血、易经卦象、脏腑经络等方面阐述"阴升阳降"理论,从济卦、脾胃升降、肝肾互用、心肾相交、任督二脉等方面具体阐述"阴升阳降"发生机理,并且通过例举阴升阳降的常用方和名老中医临证应用阴升阳降理论治疗疾病的经验,说明阴升阳降是达到阴平阳秘的必然运行形式。 展开更多
关键词 阴升阳降 阴平阳秘 心肾 肝肾 脾胃 运行
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Carbon-coating-increased working voltage and energy density towards an advanced Na3V2(PO4)2F3@C cathode in sodium-ion batteries 被引量:16
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作者 Zhen-Yi Gu Jin-Zhi Guo +6 位作者 Zhong-Hui Sun Xin-Xin Zhao Wen-Hao Li Xu Yang Hao-Jie Liang Chen-De Zhao Xing-Long Wu 《Science Bulletin》 SCIE EI CAS CSCD 2020年第9期702-710,M0003,共10页
One main challenge for phosphate cathodes in sodium-ion batteries(SIBs)is to increase the working voltage and energy density to promote its practicability.Herein,an advanced Na3V2(PO4)2F3@C cathode is prepared success... One main challenge for phosphate cathodes in sodium-ion batteries(SIBs)is to increase the working voltage and energy density to promote its practicability.Herein,an advanced Na3V2(PO4)2F3@C cathode is prepared successfully for sodium-ion full cells.It is revealed that,carbon coating can not only enhance the electronic conductivity and electrode kinetics of Na3V2(PO4)2F3@C and inhibit the growth of particles(i.e.,shorten the Na^+-migration path),but also unexpectedly for the first time adjust the dis-/charging plateaux at different voltage ranges to increase the mean voltage(from 3.59 to 3.71 V)and energy density from 336.0 to 428.5 Wh kg^-1 of phosphate cathode material.As a result,when used as cathode for SIBs,the prepared Na3V2(PO4)2F3@C delivers much improved electrochemical properties in terms of larger specifc capacity(115.9 vs.93.5 mAh g^-1),more outstanding high-rate capability(e.g.,87.3 vs.60.5 mAh g^-1 at 10 C),higher energy density,and better cycling performance,compared to pristine Na3V2(PO4)2F3.Reasons for the enhanced electrochemical properties include ionicity enhancement of lattice induced by carbon coating,improved electrode kinetics and electronic conductivity,and high stability of lattice,which is elucidated clearly through the contrastive characterization and electrochemical studies.Moreover,excellent energy-storage performance in sodium-ion full cells further demonstrate the extremely high possibility of Na3V2(PO4)2F3@C cathode for practical applications. 展开更多
关键词 Sodium-ion batteries CATHODE working voltage Na3V2(PO4)2F3 In-situ XRD
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Distribution pattern of front abutment pressure of fully-mechanized working face of soft coal isolated island 被引量:16
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作者 Xu Wenquan Wang Enyua +2 位作者 Shen Rongxi Song Dazhao Zhang Jingmin 《International Journal of Mining Science and Technology》 2012年第2期279-284,共6页
The front abutment pressure of a fully-mechanized workface of 11061 soft coal isolated island of Liangbei Coal Mine was measured and studied using a self-developed mining-induced stress monitoring system associated wi... The front abutment pressure of a fully-mechanized workface of 11061 soft coal isolated island of Liangbei Coal Mine was measured and studied using a self-developed mining-induced stress monitoring system associated with electromagnetic radiation technology, and the effects of abutment pressure distribution on strata behavior we discussed. The results indicate that the miningdnduced influencing distance advanced at the fully-mechanized working face of soft coal isolated island is larger than that at the gen- eral working face at the isolated island, besides the fracture zone in front of working face was widened to some extent, and the influencing range caused by relaxations on both roadways became bigger with the advancing working face. Moreover, it can be indicated that mining has significant effect on strata behav- ior of fully-mechanized working face of soft coal isolated island, which is mostly distributed in the area of stress concentration. The research results have an important reference value for revealing the distribution pattern of the front abutment pressure of a fully-mechanized working face of soft coal isolated island, and controlling the coal-rock dynamic disaster occurrence under similar mining conditions. 展开更多
关键词 Soft coalIsolated islandFully-mechanized working faceAbutment pressureCoal-rock dynamic disaster
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Mechanism of rock burst caused by fracture of key strata during irregular working face mining and its prevention methods 被引量:14
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作者 Zengqiang Yang Chang Liu +3 位作者 Hengzhong Zhu Fuxing Xie Linming Dou Jianhang Chen 《International Journal of Mining Science and Technology》 SCIE EI CSCD 2019年第6期889-897,共9页
To study the occurrence mechanism of rock burst during mining the irregular working face,the study took irregular panel 7447 near fault tectonic as an engineering background.The spatial fracture characteristic of over... To study the occurrence mechanism of rock burst during mining the irregular working face,the study took irregular panel 7447 near fault tectonic as an engineering background.The spatial fracture characteristic of overlying strata was analyzed by Winkler elastic foundation beam theory.Furthermore,the influence law of panel width to suspended width and limit breaking span of key strata were also analyzed by thin plate theory.Through micro-seismic monitoring,theoretical analysis,numerical simulation and working resistance of support of field measurement,this study investigated the fracture characteristic of overlying strata and mechanism of rock burst in irregular working face.The results show that the fracture characteristic of overlying strata shows a spatial trapezoid structure,with the main roof being as an undersurface.The fracture form changes from vertical‘‘O-X"type to transverse‘‘O-X"type with the increase of trapezoidal height.From the narrow mining face to the wide mining face,the suspended width of key strata is greater than its limit breaking width,and a strong dynamic load is produced by the fracture of key strata.The numerical simulation and micro-seismic monitoring results show that the initial fracture position of key strata is close to tailgate 7447.Also there is a high static load caused by fault tectonic.The dynamic and static combined load induce rock burst.Accordingly,a cooperative control technology was proposed,which can weaken dynamic load by hard roof directional hydraulic fracture and enhance surrounding rock by supporting system. 展开更多
关键词 ROCK BURST IRREGULAR working FACE Key STRATA Dynamic and static combined load Cooperative control
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Hot deformation behavior of Mg-7.22Gd-4.84Y-1.26Nd-0.58Zr magnesium alloy 被引量:13
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作者 ZHANG Kui MA Minglong +3 位作者 LI Xinggang LI Yongjun LIANG Lichao BING Mengfen 《Rare Metals》 SCIE EI CAS CSCD 2011年第1期87-93,共7页
The behavior evolvement of Mg-7.22Gd-4.84Y-1.26Nd-0.58Zr(GWN751K) magnesium alloy during the hot deformation process was discussed.The flow stress behavior of the magnesium alloy over the strain rate range of 0.002 ... The behavior evolvement of Mg-7.22Gd-4.84Y-1.26Nd-0.58Zr(GWN751K) magnesium alloy during the hot deformation process was discussed.The flow stress behavior of the magnesium alloy over the strain rate range of 0.002 to 2.000 s^-1 and in the temperature range of 623 to 773 K was studied on a Gleeble-1500D hot simulator under the maximum deformation degree of 60%.The experimental results showed that the relationship between stress and strain was obviously affected by strain rate and deformation temperature.The flow stress of GWN751K magnesium alloy during high temperature deformation could be represented by the Zener-Hollomon parameter in the hyperbolic Arrhenius-type equation.The stress exponent n and deformation activation energy Q were evaluated by linear regression analysis.The stress exponent n was fitted to be 3.16.The hot deformation activation energy of the alloy during hot deformation was 230.03 kJ/mol.The microstructures of hot deformation were also influenced by strain rate and compression temperature strongly.It was found that the alloy could be extruded at 723 K with the mechanical properties of σ0.2 = 260 MPa,σb = 320 MPa,and δ = 18%. 展开更多
关键词 magnesium alloys rare earth elements microstructure activation energy DEFORMATION hot working
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Characteristics of water inflow and chemical grouting treatment of a Liu Yuanzi Coal Mine shaft in the Ordos Basin 被引量:13
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作者 WANG Dangliang JIANG Zhenquan 《Mining Science and Technology》 EI CAS 2010年第4期607-610,共4页
During shaft constructing, a borehole water inflow of 30 m3/h was encountered in Liu Yuanzi Coal Mine in the southwestern Ordos Basin, whose aquifer is mainly cretaceous. On the basis of regional hydrogeological condi... During shaft constructing, a borehole water inflow of 30 m3/h was encountered in Liu Yuanzi Coal Mine in the southwestern Ordos Basin, whose aquifer is mainly cretaceous. On the basis of regional hydrogeological conditions, a mercury intrusion method and scanning electron microscope were used in this study. We conclude that the loose, porous and easily collapsible clay particles of the cretaceous aquifer rock mass were the major geological cause for water hazards during the construction of the shaft. We propose an approach of chemical grouting from the working surface and in the end succeeded in blocking the water. 展开更多
关键词 cretaceous aquifer chemical pre-grouting from the working face pore water water hazard
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Maximum power output of a class of irreversible non-regeneration heat engines with a non-uniform working fluid and linear phenomenological heat transfer law 被引量:13
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作者 XIA ShaoJun CHEN LinGen SUN FengRui 《Science China(Physics,Mechanics & Astronomy)》 SCIE EI CAS 2009年第12期1961-1970,共10页
Maximum power output of a class of irreversible non-regeneration heat engines with non-uniform working fluid,in which heat transfers between the working fluid and the heat reservoirs obey the linear phenomenological h... Maximum power output of a class of irreversible non-regeneration heat engines with non-uniform working fluid,in which heat transfers between the working fluid and the heat reservoirs obey the linear phenomenological heat transfer law [q ∝Δ(T-1)],are studied in this paper. Optimal control theory is used to determine the upper bounds of power of the heat engine for the lumped-parameter model and the distributed-parameter model,respectively. The results show that the maximum power output of the heat engine in the distributed-parameter model is less than or equal to that in the lumped-parameter model,which could provide more realistic guidelines for real heat engines. Analytical solutions of the maximum power output are obtained for the irreversible heat engines working between constant temperature reservoirs. For the irreversible heat engine operating between variable temperature reservoirs,a numerical example for the lumped-parameter model is provided by numerical calculation. The effects of changes of reservoir's temperature on the maximum power of the heat engine are analyzed. The obtained results are,in addition,compared with those obtained with Newtonian heat transfer law [q ∝Δ(T)]. 展开更多
关键词 linear PHENOMENOLOGICAL heat transfer law MAXIMUM power NON-UNIFORM working fluid optimal control finite time THERMODYNAMICS
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Hydraulic calculation of gravity transportation pipeline system for backfill slurry 被引量:14
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作者 张钦礼 胡冠宇 王新民 《Journal of Central South University of Technology》 EI 2008年第5期645-649,共5页
Taking cemented coal gangue pipeline transportation system in Suncun Coal Mine, Xinwen Mining Group, Shandong Province, China, as an example, the hydraulic calculation approaches and process about gravity pipeline tra... Taking cemented coal gangue pipeline transportation system in Suncun Coal Mine, Xinwen Mining Group, Shandong Province, China, as an example, the hydraulic calculation approaches and process about gravity pipeline transportation of backfill slurry were investigated. The results show that the backfill capability of the backfill system should be higher than 74.4 m3/h according to the mining production and backfill times in the mine; the minimum velocity (critical velocity) and practical working velocity of the backfill slurry are 1.44 and 3.82 m/s, respectively. Various formulae give the maximum ratio of total length to vertical height of pipeline (L/H ratio) of the backfill system of 5.4, and then the reliability and capability of the system can be evaluated. 展开更多
关键词 hydraulic calculation critical velocity working velocity pipe length-backfill depth ratio backfill capability
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育龄期职业女性外阴阴道念珠菌病致病因素及IFN-γ、TNF-α、IL-2对其预后的预测价值 被引量:14
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作者 辛丽娇 邓成敏 +2 位作者 贾丹 邓朝蓉 李琴 《中国医师杂志》 CAS 2020年第4期564-568,共5页
目的分析育龄期职业女性外阴阴道念珠菌病(VVC)致病因素及IFN-γ、TNF-α、IL-2对其预后预测价值。方法选择本院2016年6月至2017年6月妇科门诊184例患者为研究对象。采用自制一般情况调查表对患者情况进行调查,并对患者阴道分泌物取样... 目的分析育龄期职业女性外阴阴道念珠菌病(VVC)致病因素及IFN-γ、TNF-α、IL-2对其预后预测价值。方法选择本院2016年6月至2017年6月妇科门诊184例患者为研究对象。采用自制一般情况调查表对患者情况进行调查,并对患者阴道分泌物取样进行镜检以诊断VVC。根据VVC患病及复发将患者分为复发组42例,未复发组55例,以非VVC患者为对照组87例。单因素分析及多因素logistic分析VVC致病的因素。结果184例患者中共97例被确诊为VVC,发病率为52.72%。单因素分析结果显示年龄、饮用含糖饮料、吃甜食、锻炼、久坐不动、情绪状况、非经期使用护垫、穿紧身裤频率、阴道炎病史、阴道冲洗频率、刮宫史、避孕方法、首次性交年龄、性伴侣数量、性生活前后冲洗外阴与育龄期职业女性外阴阴道念珠菌病的发病有关(P<0.05)。多因素分析结果显示久坐不动、饮用含糖饮料、吃甜食、穿紧身裤频率、阴道冲洗频率、首次性交年龄、避孕方法、性伴侣数量、刮宫史、阴道炎病史、性生活前后清洗外阴均为育龄期妇女VVC患病的独立影响因素(P<0.05)。三组患者TNF-α水平对比差异无统计学意义(P>0.05),IFN-γ及IL-2水平均为复发组最低,其次为未复发组,对照组最高,差异均有统计学意义(P<0.05)。结论育龄期职业女性VVC的发生与久坐不动、饮用含糖饮料、吃甜食、穿紧身裤频率、阴道冲洗频率、首次性交年龄、避孕方法、性伴侣数量、刮宫史、阴道炎病史、性生活前后清洗外阴有关,临床上可对相关因素进行干预以降低该病的发病率。IFN-γ、IL-2水平降低可能增加VVC患病及复发风险。 展开更多
关键词 妇女 就业 育龄期 念珠菌病 外阴阴道 干扰素Γ 肿瘤坏死因子α 白细胞介素2 因素分析 统计学
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