Objectives To evaluate peripheral auditory dysfunction in senile dementia of Alzheimer’s disease (AD) and its relationship with cognitive dysfunction. Methods Pure tone thresholds,word recognition scores (WRS), acous...Objectives To evaluate peripheral auditory dysfunction in senile dementia of Alzheimer’s disease (AD) and its relationship with cognitive dysfunction. Methods Pure tone thresholds,word recognition scores (WRS), acoustic immittance and auditory brain-stem responses (ABR) were tested to evaluate the auditory function in 43 AD patients and 50 normal subjects. The test reliability in these subjects was examined before the test results were evaluated for their correlation with the Mini Mental State Examination(MMSE) score. Results There were no statistically significant differences in peripheral auditory functions between the two ears in the tested subjects or between the two groups when the auditometric results of the right ear were compared(P > 0.05). Also, there were no statistically significant differences between the two groups when audiometric test reliability, acoustic impedance and ABR results were compared(P > 0.05). Conclutions The pure tone audiometric threshold and WRS in AD patients are similar to those in comparable non-AD senile subjects. Peripheral auditory dysfunction is not related to cognitive dysfunction.展开更多
目的设计开发基于智能手机的数字助听器自主验配系统并验证该系统验配助听器的可行性。方法对11例(22耳)中度到极重度听力损失患者分别采用自主验配系统和传统助听器验配方法进行双耳助听器验配,验配前后均行纯音听阈和言语识别率测试,...目的设计开发基于智能手机的数字助听器自主验配系统并验证该系统验配助听器的可行性。方法对11例(22耳)中度到极重度听力损失患者分别采用自主验配系统和传统助听器验配方法进行双耳助听器验配,验配前后均行纯音听阈和言语识别率测试,分析结果。结果 22耳裸耳、传统验配和自主验配助听器后的平均纯音听阈分别为64.94±10.84、32.89±5.32和32.67±5.19 dB HL,言语识别率分别为57.09%±9.73%、79.45%±8.13%和78.54%±6.82%,自主验配助听器前后的平均听阈和平均言语识别率差异均有统计学意义(P<0.05),且自主验配与传统验配助听器后的纯音平均听阈值和言语识别率差异均无统计学意义(均为P>0.05)。结论应用基于智能手机的数字助听器自主验配系统对听力损失患者进行助听器验配是可行的,可以尝试采用该系统对听障患者进行助听器验配。展开更多
基金Beijing Brain Aging Key Laboratory Foundation (951890600)
文摘Objectives To evaluate peripheral auditory dysfunction in senile dementia of Alzheimer’s disease (AD) and its relationship with cognitive dysfunction. Methods Pure tone thresholds,word recognition scores (WRS), acoustic immittance and auditory brain-stem responses (ABR) were tested to evaluate the auditory function in 43 AD patients and 50 normal subjects. The test reliability in these subjects was examined before the test results were evaluated for their correlation with the Mini Mental State Examination(MMSE) score. Results There were no statistically significant differences in peripheral auditory functions between the two ears in the tested subjects or between the two groups when the auditometric results of the right ear were compared(P > 0.05). Also, there were no statistically significant differences between the two groups when audiometric test reliability, acoustic impedance and ABR results were compared(P > 0.05). Conclutions The pure tone audiometric threshold and WRS in AD patients are similar to those in comparable non-AD senile subjects. Peripheral auditory dysfunction is not related to cognitive dysfunction.
文摘目的设计开发基于智能手机的数字助听器自主验配系统并验证该系统验配助听器的可行性。方法对11例(22耳)中度到极重度听力损失患者分别采用自主验配系统和传统助听器验配方法进行双耳助听器验配,验配前后均行纯音听阈和言语识别率测试,分析结果。结果 22耳裸耳、传统验配和自主验配助听器后的平均纯音听阈分别为64.94±10.84、32.89±5.32和32.67±5.19 dB HL,言语识别率分别为57.09%±9.73%、79.45%±8.13%和78.54%±6.82%,自主验配助听器前后的平均听阈和平均言语识别率差异均有统计学意义(P<0.05),且自主验配与传统验配助听器后的纯音平均听阈值和言语识别率差异均无统计学意义(均为P>0.05)。结论应用基于智能手机的数字助听器自主验配系统对听力损失患者进行助听器验配是可行的,可以尝试采用该系统对听障患者进行助听器验配。