目的比较不同人工晶状体植入对年龄相关性白内障患者客观视觉质量及视觉相关生活质量的影响及相互关系。方法采用前瞻性非随机对照研究设计,收集2018年1月至8月在西南医科大学附属医院眼科行白内障超声乳化吸出联合人工晶状体植入术的...目的比较不同人工晶状体植入对年龄相关性白内障患者客观视觉质量及视觉相关生活质量的影响及相互关系。方法采用前瞻性非随机对照研究设计,收集2018年1月至8月在西南医科大学附属医院眼科行白内障超声乳化吸出联合人工晶状体植入术的年龄相关性白内障患者66例(90眼),其中植入单焦点人工晶状体34例(52眼)患者为单焦点组,植入衍射型多焦点人工晶状体32例(38眼)患者为多焦点组。测量2组患者术前及术后3个月术眼裸眼远近视力(uncorrected distance visual acuity,UCDVA;uncorrected near visual acuity,UCNVA),最佳矫正远、近视力(best-corrected distance visual acuity,BCDVA;best-corrected near visual acuity,BCNVA),采用中文版25项美国国家眼科研究所视觉功能问卷调查(25-item national eye institute visual function questionnaire,NEI-VFQ-25)评估患者手术前后的视觉相关生活质量,结合双通道视觉质量分析仪OQAS II对患者术眼手术前后客观散射指数(objective scatter index,OSI)、调制传递函数截止频率(modulation transfer function cut off,MTF cut off)、斯特列尔比(strehl ratio,SR)、对比度为100%、20%及9%的OQAS值(OV100、OV20、OV9)以及伪调节力进行测量。结果两组患者术后UCDVA及BCDVA均较术前明显提高(t=-27.763、-16.772、-13.429、-12.936,均为P<0.01),多焦点组患者术后UCNVA及BCNVA均较术前明显提高(均为P<0.05),多焦点组术后UCNVA较单焦点组高(t=-6.364,P<0.01),2组间术后UCDVA、BCDVA、BCNVA差异均无统计学意义(均为P>0.05)。多焦点组术后总体视觉、近距离工作评分均较单焦点组好(均为P<0.05),单焦点组术后色彩视觉评分较多焦点组好(P<0.05),2组患者术后的独立性及精神健康均较术前改善(均为P<0.05),2组间术后差异均无统计学意义(均为P>0.05)。多焦点组术后OSI、调节幅度较单焦点组均高(均为P<0.05),MTF cut off、OV20、OV9较单焦点组均低(均为P<0.05)。结论植入�展开更多
<strong>Background:</strong> The aim of this study was to evaluate vision related quality of life (VRQoL) in patients with retinitis pigmentosa (RP) after suprachoroidal umbilical cord derived mesenchymal ...<strong>Background:</strong> The aim of this study was to evaluate vision related quality of life (VRQoL) in patients with retinitis pigmentosa (RP) after suprachoroidal umbilical cord derived mesenchymal stem cell (UC-MSC) treatment. <strong>Methods:</strong> The patients were evaluated regarding to the VRQoL before the treatment and at the end of the first year. The study was performed in an affiliated hospital of a university between 2018 and 2020. The patients were operated by a single surgeon and evaluated at baseline and at first, sixth and twelfth month after stem cell implantation. To assess patients’ subjective visual situation, we used Impact of Vision Impairment (IVI) Profile 28-item questionnaire. It basically evaluated vision-related activities in three subscales: “reading and accessing information”, “mobility and independence” and “emotional well-being”. This test is established to assess VRQoL in low vision patients. <strong>Results:</strong> A total of 123 people, ranging in age from 18 to 48 years, participated in the study and 43.9% (n = 54) were women. The study patients were followed up for one year and the questionnaire was filled by patients at baseline and one year after surgery. In all groups, no difficulty was observed in understanding the questionnaire. The results showed significant improvements in VRQoL after stem cell treatment (p < 0.05). The analysis of each subscale score including “reading and accessing information”, “mobility and independence” and “emotional well-being” before and after treatment showed significant improvements in all subscale scores (p < 0.05). <strong>Conclusions:</strong> IVI 28 item questionnaire seems to be an effective test for the assessment of VRQoL in low vision patients. The suprachoroidal implantation of UC-MSC for the treatment of RP can improve the quality of life of these patients.展开更多
目的:对比分析双眼三焦点IOL(AT LISA tri 839MP IOL)植入与一眼植入AT LISA tri 839MP IOL而另一眼植入非球面单焦点IOL患者术后视觉相关生活质量。方法:前瞻性临床研究。收集2018-05/2019-08在我院行白内障超声乳化联合三焦点AT LISA ...目的:对比分析双眼三焦点IOL(AT LISA tri 839MP IOL)植入与一眼植入AT LISA tri 839MP IOL而另一眼植入非球面单焦点IOL患者术后视觉相关生活质量。方法:前瞻性临床研究。收集2018-05/2019-08在我院行白内障超声乳化联合三焦点AT LISA tri 839MP IOL植入的患者45例,按是否双眼植入AT LISA tri 839MP IOL分为两组,双眼植入者24例纳入双眼三焦点组;一眼植入AT LISA tri 839MP IOL而另一眼植入非球面单焦点IOL者21例纳入单眼三焦点组。术后3mo,检测两组患者裸眼视力及等效球镜度,并通过中国版视功能指数量表(VF-14-CN)评价视觉相关生活质量,评估日常生活脱镜率及满意度。结果:术后3mo,双眼三焦点组和单眼三焦点组患者双眼裸眼远、中、近视力均无明显差异(P>0.05),两组患者VF-14-CN问卷得分(96.2±0.50、92.43±1.32分)、日常生活脱镜率(96%、90%)及患者主观满意度(96%、95%)均无差异(P>0.05)。结论:双眼植入AT LISA tri 839MP IOL和一眼植入AT LISA tri 839MP IOL而另一眼植入非球面单焦点IOL的患者术后均具有良好的双眼裸眼远、中、近视力,术后视觉相关生活质量、脱镜率、满意度无明显差异。对一眼不适合植入三焦点IOL或既往一眼已植入非球面单焦点IOL的患者,可考虑另一眼行三焦点IOL植入以满足患者双眼全程视力的要求。展开更多
文摘目的比较不同人工晶状体植入对年龄相关性白内障患者客观视觉质量及视觉相关生活质量的影响及相互关系。方法采用前瞻性非随机对照研究设计,收集2018年1月至8月在西南医科大学附属医院眼科行白内障超声乳化吸出联合人工晶状体植入术的年龄相关性白内障患者66例(90眼),其中植入单焦点人工晶状体34例(52眼)患者为单焦点组,植入衍射型多焦点人工晶状体32例(38眼)患者为多焦点组。测量2组患者术前及术后3个月术眼裸眼远近视力(uncorrected distance visual acuity,UCDVA;uncorrected near visual acuity,UCNVA),最佳矫正远、近视力(best-corrected distance visual acuity,BCDVA;best-corrected near visual acuity,BCNVA),采用中文版25项美国国家眼科研究所视觉功能问卷调查(25-item national eye institute visual function questionnaire,NEI-VFQ-25)评估患者手术前后的视觉相关生活质量,结合双通道视觉质量分析仪OQAS II对患者术眼手术前后客观散射指数(objective scatter index,OSI)、调制传递函数截止频率(modulation transfer function cut off,MTF cut off)、斯特列尔比(strehl ratio,SR)、对比度为100%、20%及9%的OQAS值(OV100、OV20、OV9)以及伪调节力进行测量。结果两组患者术后UCDVA及BCDVA均较术前明显提高(t=-27.763、-16.772、-13.429、-12.936,均为P<0.01),多焦点组患者术后UCNVA及BCNVA均较术前明显提高(均为P<0.05),多焦点组术后UCNVA较单焦点组高(t=-6.364,P<0.01),2组间术后UCDVA、BCDVA、BCNVA差异均无统计学意义(均为P>0.05)。多焦点组术后总体视觉、近距离工作评分均较单焦点组好(均为P<0.05),单焦点组术后色彩视觉评分较多焦点组好(P<0.05),2组患者术后的独立性及精神健康均较术前改善(均为P<0.05),2组间术后差异均无统计学意义(均为P>0.05)。多焦点组术后OSI、调节幅度较单焦点组均高(均为P<0.05),MTF cut off、OV20、OV9较单焦点组均低(均为P<0.05)。结论植入�
文摘<strong>Background:</strong> The aim of this study was to evaluate vision related quality of life (VRQoL) in patients with retinitis pigmentosa (RP) after suprachoroidal umbilical cord derived mesenchymal stem cell (UC-MSC) treatment. <strong>Methods:</strong> The patients were evaluated regarding to the VRQoL before the treatment and at the end of the first year. The study was performed in an affiliated hospital of a university between 2018 and 2020. The patients were operated by a single surgeon and evaluated at baseline and at first, sixth and twelfth month after stem cell implantation. To assess patients’ subjective visual situation, we used Impact of Vision Impairment (IVI) Profile 28-item questionnaire. It basically evaluated vision-related activities in three subscales: “reading and accessing information”, “mobility and independence” and “emotional well-being”. This test is established to assess VRQoL in low vision patients. <strong>Results:</strong> A total of 123 people, ranging in age from 18 to 48 years, participated in the study and 43.9% (n = 54) were women. The study patients were followed up for one year and the questionnaire was filled by patients at baseline and one year after surgery. In all groups, no difficulty was observed in understanding the questionnaire. The results showed significant improvements in VRQoL after stem cell treatment (p < 0.05). The analysis of each subscale score including “reading and accessing information”, “mobility and independence” and “emotional well-being” before and after treatment showed significant improvements in all subscale scores (p < 0.05). <strong>Conclusions:</strong> IVI 28 item questionnaire seems to be an effective test for the assessment of VRQoL in low vision patients. The suprachoroidal implantation of UC-MSC for the treatment of RP can improve the quality of life of these patients.
文摘目的:对比分析双眼三焦点IOL(AT LISA tri 839MP IOL)植入与一眼植入AT LISA tri 839MP IOL而另一眼植入非球面单焦点IOL患者术后视觉相关生活质量。方法:前瞻性临床研究。收集2018-05/2019-08在我院行白内障超声乳化联合三焦点AT LISA tri 839MP IOL植入的患者45例,按是否双眼植入AT LISA tri 839MP IOL分为两组,双眼植入者24例纳入双眼三焦点组;一眼植入AT LISA tri 839MP IOL而另一眼植入非球面单焦点IOL者21例纳入单眼三焦点组。术后3mo,检测两组患者裸眼视力及等效球镜度,并通过中国版视功能指数量表(VF-14-CN)评价视觉相关生活质量,评估日常生活脱镜率及满意度。结果:术后3mo,双眼三焦点组和单眼三焦点组患者双眼裸眼远、中、近视力均无明显差异(P>0.05),两组患者VF-14-CN问卷得分(96.2±0.50、92.43±1.32分)、日常生活脱镜率(96%、90%)及患者主观满意度(96%、95%)均无差异(P>0.05)。结论:双眼植入AT LISA tri 839MP IOL和一眼植入AT LISA tri 839MP IOL而另一眼植入非球面单焦点IOL的患者术后均具有良好的双眼裸眼远、中、近视力,术后视觉相关生活质量、脱镜率、满意度无明显差异。对一眼不适合植入三焦点IOL或既往一眼已植入非球面单焦点IOL的患者,可考虑另一眼行三焦点IOL植入以满足患者双眼全程视力的要求。
