Background:Aging is almost assocaited with inner ear disorders(InEarDs)by means of age-related hearing impairment(ARHI)or vertigo-anddizziness as well as the carotid artery disease requiring revascularization(CAD-R).O...Background:Aging is almost assocaited with inner ear disorders(InEarDs)by means of age-related hearing impairment(ARHI)or vertigo-anddizziness as well as the carotid artery disease requiring revascularization(CAD-R).Objective:The present study aimed to study the prevalence and characteristics of InEarDs in older adults diagnosed with CAD-R.The other aim was to determine if InEarDs in CAD-R patients is age-related or might be explained by a concomitant CAD-R.Method:A retrospective,case-control study was conducted at the Mayo Clinic,Florida.The study cohort includes 919 patients who had CAD-R.The control group consisted of 244 age-and gender-matched patients presenting with cardiac or peripheral artery disease.The InEarDs were assessed based on the diagnosis upon presentation to the Audiology Clinic and follow-up.Results:Of the 919,348 had ARHI that includes significant peripheral signs and central symptoms(24.9%),vertigo-and-dizziness events that are recurrent and persistent with normal objective vestibular testing(12.9%),or a combination of both(11.0%).These percentages were significantly higher in the study group relative to the control group.After adjustment for the vascular risk factors,the study group had significantly higher odds of ARHI(OR=1.94;95%CI:1.09-3.44;P<0.05).Conclusion:CAD-R patients had significantly higher InEarDs than the control group.CAD-R is more likely to be associated with ARHI rather than the vertigo-and-dizziness even after adjusting for the vascular risk factors.展开更多
文摘Background:Aging is almost assocaited with inner ear disorders(InEarDs)by means of age-related hearing impairment(ARHI)or vertigo-anddizziness as well as the carotid artery disease requiring revascularization(CAD-R).Objective:The present study aimed to study the prevalence and characteristics of InEarDs in older adults diagnosed with CAD-R.The other aim was to determine if InEarDs in CAD-R patients is age-related or might be explained by a concomitant CAD-R.Method:A retrospective,case-control study was conducted at the Mayo Clinic,Florida.The study cohort includes 919 patients who had CAD-R.The control group consisted of 244 age-and gender-matched patients presenting with cardiac or peripheral artery disease.The InEarDs were assessed based on the diagnosis upon presentation to the Audiology Clinic and follow-up.Results:Of the 919,348 had ARHI that includes significant peripheral signs and central symptoms(24.9%),vertigo-and-dizziness events that are recurrent and persistent with normal objective vestibular testing(12.9%),or a combination of both(11.0%).These percentages were significantly higher in the study group relative to the control group.After adjustment for the vascular risk factors,the study group had significantly higher odds of ARHI(OR=1.94;95%CI:1.09-3.44;P<0.05).Conclusion:CAD-R patients had significantly higher InEarDs than the control group.CAD-R is more likely to be associated with ARHI rather than the vertigo-and-dizziness even after adjusting for the vascular risk factors.
