This review updates the current status of immunology research under the influence of genomics,both conceptually and technologically.It particularly highlights the advantages of employing the high-throughput and large-...This review updates the current status of immunology research under the influence of genomics,both conceptually and technologically.It particularly highlights the advantages of employing the high-throughput and large-scale technology,the large genomic database,and bioinformatic power in the immunology research.The fast development in the fields of basic immunology,clinical immunology(tumor and infectious immunology) and vaccine designing is illustrated with respect to the successful usage of genomic strategy.We also speculate the future research directions of immunology in the era of genomics and post-genomics.展开更多
基金Supported by the National High-Tech Research and Development Program of China (Grant No.2006AA02A252)National Natural Science Foundation of China (Grant No.30771965)Shanghai Pujiang Program (Grant No.07pj14066)
文摘This review updates the current status of immunology research under the influence of genomics,both conceptually and technologically.It particularly highlights the advantages of employing the high-throughput and large-scale technology,the large genomic database,and bioinformatic power in the immunology research.The fast development in the fields of basic immunology,clinical immunology(tumor and infectious immunology) and vaccine designing is illustrated with respect to the successful usage of genomic strategy.We also speculate the future research directions of immunology in the era of genomics and post-genomics.
基金supported by the Strategic Priority Research Program of the Chinese Academy of Sciences(XDB29030104)the National Natural Science Foundation of China (31870731, 31971129)+3 种基金the Fundamental Research Funds for the Central Universities (WK9100000001)USTC New Medicine Joint Fund Training Program(WK9110000136)China Postdoctoral Science Foundation(2020M670084ZX)Hefei Comprehensive National Science Center (BJ9100000005)。
