AIM:To compare the fast-track rehabilitation program and conventional care for patients after resection of colorectal cancer.METHODS:One hundred and six consecutive patients who underwent fast-track rehabilitation pro...AIM:To compare the fast-track rehabilitation program and conventional care for patients after resection of colorectal cancer.METHODS:One hundred and six consecutive patients who underwent fast-track rehabilitation program were encouraged to have early oral feeding and movement for early discharge,while 104 consecutive patients underwent conventional care after resection of colorectal cancer.Their gastrointestinal functions,postoperative complications and hospital stay time were recorded.RESULTS:The restoration time of gastrointestinal functions in the patients was significantly faster after fasttrack rehabilitation program than after conventional care(2.1 d vs 3.2 d,P < 0.01).The percentage of patients who developed complications was significantly lower 30 d after fast-track rehabilitation program than after conventional care(13.2% vs 26.9%,P < 0.05).Also,the percentage of patients who had general complications was significantly lower 30 d after fast-track rehabilitation program than after conventional care(6.6% vs 15.4%,P < 0.05).The postoperative hospital stay time of the patients was shorter after fast-track rehabilitation program than after conventional care(5 d vs 7 d,P < 0.01).No significant difference was observed in the readmission rate 30 d after fast-track rehabilitation program and conventional care(3.8% vs 8.7%).CONCLUSION:The fast-track rehabilitation program can significantly decrease the complications and shorten the time of postoperative hospital stay of patients after resection colorectal cancer.展开更多
AIM:To compare the long-term outcome of percutaneous vs surgical radiofrequency ablation(RFA) for hepatocellular carcinoma(HCC) in dangerous locations.METHODS:One hundred and sixty-two patients with HCC in dangerous l...AIM:To compare the long-term outcome of percutaneous vs surgical radiofrequency ablation(RFA) for hepatocellular carcinoma(HCC) in dangerous locations.METHODS:One hundred and sixty-two patients with HCC in dangerous locations treated with percutaneous or surgical RFA were enrolled in this study.The patients were divided into percutaneous RFA group and surgical RFA group.After the patients were regularly followed up for a long time,their curative rate,hospital stay time,postoperative complications and 5-year local tumor progression were compared and analyzed.RESULTS:No significant difference was observed in curative rate between the two groups(91.3% vs 96.8%,P = 0.841).The hospital stay time was longer and more analgesics were required while the incidence of bile duct injury and RFA-related hemorrhage was lower in surgical RFA group than in percutaneous RFA group(P < 0.05).The local progression rate of HCC in dangerous locations was significantly lower in surgical RFA group than in percutaneous RFA group(P = 0.05).The relative risk of local tumor progression was 14.315 in percutaneous RFA group.CONCLUSION:The incidence of severe postoperative complications and local tumor progression is lower after surgical RFA than after percutaneous RFA.展开更多
基于严格设计随机对照试验（RCTs）的直接比较（direct comparison）或称为头对头比较（head to head comparison）的系统评价,已被公认为是评价干预措施疗效的最高级别证据,称之为传统系统评价.但是,如果想进行一个系统评价,目的是比...基于严格设计随机对照试验（RCTs）的直接比较（direct comparison）或称为头对头比较（head to head comparison）的系统评价,已被公认为是评价干预措施疗效的最高级别证据,称之为传统系统评价.但是,如果想进行一个系统评价,目的是比较两种干预措施A vs B的效果,但目前的RCTs没有两者的直接比较研究,却都有同干预措施C的比较（即A vs C和B vs C）,此时,可以将C作为公共比较组,借助间接比较方法得出A vs B的效果,或者虽然有直接比较研究证据,但这些研究数量较少或质量较低,此时也可以用间接比较证据进行补充.展开更多
Nutrient resorption is an important conservation mechanism for plants to overcome nutrient limitation in the less fertile area of desertifled land. In the semi-arid Horqin Sandy Land of Northern China, the shrub Artem...Nutrient resorption is an important conservation mechanism for plants to overcome nutrient limitation in the less fertile area of desertifled land. In the semi-arid Horqin Sandy Land of Northern China, the shrub Artemisia ha/odendron usually colonizes into the bare ground of severely desertified land as a pioneer species. It is, therefore, expected that A. ha/odendron will be less dependent on current nutrient uptake through efficient and proficient re- sorption of nutrients. In this study, we found that averaged nitrogen （N） and phosphorus （P） concentrations in se- nesced leaves significantly varied from 12.3 and 1.2 mg/g in the shifting sand dune to 15.9 and 1.9 mg/g in the fixed sand dune, respectively, suggesting that foliar N and P resorption of A. ha/odendron were more proficient in the shifting sand dune. In particular, positive relationships between nutrient concentrations in senesced leaves and soil nutrient availability indicate that A. ha/odendron in infertile habitats is more likely to manage with a low level of nu- trients in senesced leaves, giving this species an advantage in infertile soil. Moreover, foliar N- and P-resorption efficiencies and proficiencies showed limited inter-annual variability although annual precipitation varied greatly among 2007-2009. However, N and P resorption of A. ha/oc/endron were not more efficient and proficient than those previously reported for other shrubs, indicating that the pioneer shrub in sand dune environments does not rely more heavily than other plants on the process of resorption to conserve nutrients. Incomplete resorption of nutrients in A. halodendron suggests that senesced-leaf fall would return litter with high quality to the soil, and thereby would indirectly improve soil nutrient availability. The restoration of desertified land, therefore, may be ac- celerated after A. halodendron pioneers into shifting sand dunes.展开更多
基金Supported by Social Development Fund of Jiangsu Province,No. BS2007054
文摘AIM:To compare the fast-track rehabilitation program and conventional care for patients after resection of colorectal cancer.METHODS:One hundred and six consecutive patients who underwent fast-track rehabilitation program were encouraged to have early oral feeding and movement for early discharge,while 104 consecutive patients underwent conventional care after resection of colorectal cancer.Their gastrointestinal functions,postoperative complications and hospital stay time were recorded.RESULTS:The restoration time of gastrointestinal functions in the patients was significantly faster after fasttrack rehabilitation program than after conventional care(2.1 d vs 3.2 d,P < 0.01).The percentage of patients who developed complications was significantly lower 30 d after fast-track rehabilitation program than after conventional care(13.2% vs 26.9%,P < 0.05).Also,the percentage of patients who had general complications was significantly lower 30 d after fast-track rehabilitation program than after conventional care(6.6% vs 15.4%,P < 0.05).The postoperative hospital stay time of the patients was shorter after fast-track rehabilitation program than after conventional care(5 d vs 7 d,P < 0.01).No significant difference was observed in the readmission rate 30 d after fast-track rehabilitation program and conventional care(3.8% vs 8.7%).CONCLUSION:The fast-track rehabilitation program can significantly decrease the complications and shorten the time of postoperative hospital stay of patients after resection colorectal cancer.
文摘AIM:To compare the long-term outcome of percutaneous vs surgical radiofrequency ablation(RFA) for hepatocellular carcinoma(HCC) in dangerous locations.METHODS:One hundred and sixty-two patients with HCC in dangerous locations treated with percutaneous or surgical RFA were enrolled in this study.The patients were divided into percutaneous RFA group and surgical RFA group.After the patients were regularly followed up for a long time,their curative rate,hospital stay time,postoperative complications and 5-year local tumor progression were compared and analyzed.RESULTS:No significant difference was observed in curative rate between the two groups(91.3% vs 96.8%,P = 0.841).The hospital stay time was longer and more analgesics were required while the incidence of bile duct injury and RFA-related hemorrhage was lower in surgical RFA group than in percutaneous RFA group(P < 0.05).The local progression rate of HCC in dangerous locations was significantly lower in surgical RFA group than in percutaneous RFA group(P = 0.05).The relative risk of local tumor progression was 14.315 in percutaneous RFA group.CONCLUSION:The incidence of severe postoperative complications and local tumor progression is lower after surgical RFA than after percutaneous RFA.
文摘基于严格设计随机对照试验（RCTs）的直接比较（direct comparison）或称为头对头比较（head to head comparison）的系统评价,已被公认为是评价干预措施疗效的最高级别证据,称之为传统系统评价.但是,如果想进行一个系统评价,目的是比较两种干预措施A vs B的效果,但目前的RCTs没有两者的直接比较研究,却都有同干预措施C的比较（即A vs C和B vs C）,此时,可以将C作为公共比较组,借助间接比较方法得出A vs B的效果,或者虽然有直接比较研究证据,但这些研究数量较少或质量较低,此时也可以用间接比较证据进行补充.
基金National Key Technology R&D Program (Y113911001)Strategic Priority Research Program of the Chinese Academy of Sciences (XDA05050406)National Natural Science Foundation of China (31270501, 30970471)
文摘Nutrient resorption is an important conservation mechanism for plants to overcome nutrient limitation in the less fertile area of desertifled land. In the semi-arid Horqin Sandy Land of Northern China, the shrub Artemisia ha/odendron usually colonizes into the bare ground of severely desertified land as a pioneer species. It is, therefore, expected that A. ha/odendron will be less dependent on current nutrient uptake through efficient and proficient re- sorption of nutrients. In this study, we found that averaged nitrogen （N） and phosphorus （P） concentrations in se- nesced leaves significantly varied from 12.3 and 1.2 mg/g in the shifting sand dune to 15.9 and 1.9 mg/g in the fixed sand dune, respectively, suggesting that foliar N and P resorption of A. ha/odendron were more proficient in the shifting sand dune. In particular, positive relationships between nutrient concentrations in senesced leaves and soil nutrient availability indicate that A. ha/odendron in infertile habitats is more likely to manage with a low level of nu- trients in senesced leaves, giving this species an advantage in infertile soil. Moreover, foliar N- and P-resorption efficiencies and proficiencies showed limited inter-annual variability although annual precipitation varied greatly among 2007-2009. However, N and P resorption of A. ha/oc/endron were not more efficient and proficient than those previously reported for other shrubs, indicating that the pioneer shrub in sand dune environments does not rely more heavily than other plants on the process of resorption to conserve nutrients. Incomplete resorption of nutrients in A. halodendron suggests that senesced-leaf fall would return litter with high quality to the soil, and thereby would indirectly improve soil nutrient availability. The restoration of desertified land, therefore, may be ac- celerated after A. halodendron pioneers into shifting sand dunes.
