Panel data combine cross-section data and time series data. If the cross-section is locations, there is a need to check the correlation among locations. ρ and λ are parameters in generalized spatial model to cover e...Panel data combine cross-section data and time series data. If the cross-section is locations, there is a need to check the correlation among locations. ρ and λ are parameters in generalized spatial model to cover effect of correlation between locations. Value of ρ or λ will influence the goodness of fit model, so it is important to make parameter estimation. The effect of another location is covered by making contiguity matrix until it gets spatial weighted matrix (W). There are some types of W—uniform W, binary W, kernel Gaussian W and some W from real case of economics condition or transportation condition from locations. This study is aimed to compare uniform W and kernel Gaussian W in spatial panel data model using RMSE value. The result of analysis showed that uniform weight had RMSE value less than kernel Gaussian model. Uniform W had stabil value for all the combinations.展开更多
Uniform molecular weight(Mw)chitosan(CS)is highly demanded in medical biomaterial industry.This present article described heterogeneous degradation of CS in aqueous HCl/ethanol solution,in which progress uniform Mw CS...Uniform molecular weight(Mw)chitosan(CS)is highly demanded in medical biomaterial industry.This present article described heterogeneous degradation of CS in aqueous HCl/ethanol solution,in which progress uniform Mw CS was successfully prepared.The Mw distribution of CS was measured by gel permeation chromatography(GPC)analysis.Moreover,the structure and properties of degraded CS were characterized by Fourier transform infrared spectroscopy(FT-IR),nuclear magnetic resonance spectroscopy(^1H NMR),X-ray diffraction(XRD)and thermogravimetric(TG)analysis.In addition,the biocompatibility of degraded CS was also assessed by hemolysis rate(HR)measurement.The Mw of CS dramatically decreased from 246 KDa to 76 k Da at the initial 30 min,and stabilized at 18 kDa after 24 h.GPC analysis results showed that the degraded CS molecular become homogenization.FT-IR and 1 H NMR analysis confirmed the basic structure of CS molecular backbone was not destroyed during this progress.Besides,the water solubility of CS was not significantly influenced by this reaction.Moreover,the XRD analysis revealed that crystallinity of degraded CS increased from 70.32% to 99.25%with time.The TG analysis showed improved thermal stability of degraded CS.HR measurement demonstrated the degraded CS possessed excellent biocompatibility.This simple and efficient heterogeneous degradation would open up a new route to produce uniform Mw CS.展开更多
文摘Panel data combine cross-section data and time series data. If the cross-section is locations, there is a need to check the correlation among locations. ρ and λ are parameters in generalized spatial model to cover effect of correlation between locations. Value of ρ or λ will influence the goodness of fit model, so it is important to make parameter estimation. The effect of another location is covered by making contiguity matrix until it gets spatial weighted matrix (W). There are some types of W—uniform W, binary W, kernel Gaussian W and some W from real case of economics condition or transportation condition from locations. This study is aimed to compare uniform W and kernel Gaussian W in spatial panel data model using RMSE value. The result of analysis showed that uniform weight had RMSE value less than kernel Gaussian model. Uniform W had stabil value for all the combinations.
基金supported by the National Natural Science Foundation of China(Nos.U1706212 and 81671828)
文摘Uniform molecular weight(Mw)chitosan(CS)is highly demanded in medical biomaterial industry.This present article described heterogeneous degradation of CS in aqueous HCl/ethanol solution,in which progress uniform Mw CS was successfully prepared.The Mw distribution of CS was measured by gel permeation chromatography(GPC)analysis.Moreover,the structure and properties of degraded CS were characterized by Fourier transform infrared spectroscopy(FT-IR),nuclear magnetic resonance spectroscopy(^1H NMR),X-ray diffraction(XRD)and thermogravimetric(TG)analysis.In addition,the biocompatibility of degraded CS was also assessed by hemolysis rate(HR)measurement.The Mw of CS dramatically decreased from 246 KDa to 76 k Da at the initial 30 min,and stabilized at 18 kDa after 24 h.GPC analysis results showed that the degraded CS molecular become homogenization.FT-IR and 1 H NMR analysis confirmed the basic structure of CS molecular backbone was not destroyed during this progress.Besides,the water solubility of CS was not significantly influenced by this reaction.Moreover,the XRD analysis revealed that crystallinity of degraded CS increased from 70.32% to 99.25%with time.The TG analysis showed improved thermal stability of degraded CS.HR measurement demonstrated the degraded CS possessed excellent biocompatibility.This simple and efficient heterogeneous degradation would open up a new route to produce uniform Mw CS.
