Dysplasia epiphysealis hemimelica(DEH),or Trevor’s disease,is an osteocartilaginous epiphyseal overgrowth typically occurring in children.The literature reports6 adult cases and none describe recurrence requiring add...Dysplasia epiphysealis hemimelica(DEH),or Trevor’s disease,is an osteocartilaginous epiphyseal overgrowth typically occurring in children.The literature reports6 adult cases and none describe recurrence requiring additional procedures.We present a new-onset proximal tibial DEH in an adult recurring approximately 3 years after open excision.A 39-year-old female presented with a history of right knee pain,swelling,and instability.Physical examination revealed a firm proximal tibial mass.Computed tomography(CT)imaging showed an exophytic,lobulated,sclerotic mass involving the anterolateral margin of the lateral tibial plateau.Magnetic resonance imaging was suggestive of an osteochondroma.The patient underwent curettage of the lesion due to its periarticular location.Histology revealed benign and reactive bone and cartilage consistent with periosteal chondroma.Two and a half years later,the patient presented with a firm,palpable mass larger than the initial lesion.CT revealed a lateral tibial plateau sclerotic mass consistent with recurrent intraarticular DEH.A complete excision was performed and histology showed sclerotic bone with overlying cartilage consistent with exostosis.DEH is a rare epiphyseal osteocartilaginous outgrowth frequently occurring in the long bones of children less than 8 years old.DEH resembles an osteochondroma due to its pediatric presentation and similar histologic appearance.Adultonset cases comprise less than 1%of reported cases.Recurrence rate after surgical intervention is unknown.Only 1 such case,occurring in a child,has been described.Clinicians contemplating operative treatment for DEH should note the potential for recurrence and consider complete excision.A follow-up period of several years may be warranted to identify recurrent lesions.展开更多
本文追忆了STS重要学者特里弗·平齐教授,并以平齐教授为基点,展现了20世纪70、80年代英国独特的开放性学术文化,正是当时不设学科边界的跨学科对话促成了以科学和技术为研究对象的各领域学者——科学社会学家、科学史家和科学哲学...本文追忆了STS重要学者特里弗·平齐教授,并以平齐教授为基点,展现了20世纪70、80年代英国独特的开放性学术文化,正是当时不设学科边界的跨学科对话促成了以科学和技术为研究对象的各领域学者——科学社会学家、科学史家和科学哲学家的交流与合作,成就了科学与技术元勘(Science and Technology Studies,STS)的诞生和发展。而平齐教授正是这其中的核心人物,他的开放性、谦逊和广博的兴趣使他的职业生涯充满了与全球各地的学者所合作的五花八门的有趣研究,他的成就巨大,是科学和技术的社会研究领域中最伟大的人物之一。展开更多
7月11日,适逢Savant在上海举办'智享生活交流会',《家庭影院技术》杂志有幸采访到专程自美国赶来的Savant国际销售总监Trevor de Maat先生,请他就Savant的市场现状、中国战略以及智能家居行业的发展等谈了自己的看法。以下是经...7月11日,适逢Savant在上海举办'智享生活交流会',《家庭影院技术》杂志有幸采访到专程自美国赶来的Savant国际销售总监Trevor de Maat先生,请他就Savant的市场现状、中国战略以及智能家居行业的发展等谈了自己的看法。以下是经编辑后的受访内容。自定义设置,让用户成为智能家居的主导美国是全球最大的智能家居市场,也是Savant最成熟和最重要的市场。展开更多
基金Cooper University Hospital (Camden,NJ,United States) for supporting to this work
文摘Dysplasia epiphysealis hemimelica(DEH),or Trevor’s disease,is an osteocartilaginous epiphyseal overgrowth typically occurring in children.The literature reports6 adult cases and none describe recurrence requiring additional procedures.We present a new-onset proximal tibial DEH in an adult recurring approximately 3 years after open excision.A 39-year-old female presented with a history of right knee pain,swelling,and instability.Physical examination revealed a firm proximal tibial mass.Computed tomography(CT)imaging showed an exophytic,lobulated,sclerotic mass involving the anterolateral margin of the lateral tibial plateau.Magnetic resonance imaging was suggestive of an osteochondroma.The patient underwent curettage of the lesion due to its periarticular location.Histology revealed benign and reactive bone and cartilage consistent with periosteal chondroma.Two and a half years later,the patient presented with a firm,palpable mass larger than the initial lesion.CT revealed a lateral tibial plateau sclerotic mass consistent with recurrent intraarticular DEH.A complete excision was performed and histology showed sclerotic bone with overlying cartilage consistent with exostosis.DEH is a rare epiphyseal osteocartilaginous outgrowth frequently occurring in the long bones of children less than 8 years old.DEH resembles an osteochondroma due to its pediatric presentation and similar histologic appearance.Adultonset cases comprise less than 1%of reported cases.Recurrence rate after surgical intervention is unknown.Only 1 such case,occurring in a child,has been described.Clinicians contemplating operative treatment for DEH should note the potential for recurrence and consider complete excision.A follow-up period of several years may be warranted to identify recurrent lesions.
文摘本文追忆了STS重要学者特里弗·平齐教授,并以平齐教授为基点,展现了20世纪70、80年代英国独特的开放性学术文化,正是当时不设学科边界的跨学科对话促成了以科学和技术为研究对象的各领域学者——科学社会学家、科学史家和科学哲学家的交流与合作,成就了科学与技术元勘(Science and Technology Studies,STS)的诞生和发展。而平齐教授正是这其中的核心人物,他的开放性、谦逊和广博的兴趣使他的职业生涯充满了与全球各地的学者所合作的五花八门的有趣研究,他的成就巨大,是科学和技术的社会研究领域中最伟大的人物之一。
文摘7月11日,适逢Savant在上海举办'智享生活交流会',《家庭影院技术》杂志有幸采访到专程自美国赶来的Savant国际销售总监Trevor de Maat先生,请他就Savant的市场现状、中国战略以及智能家居行业的发展等谈了自己的看法。以下是经编辑后的受访内容。自定义设置,让用户成为智能家居的主导美国是全球最大的智能家居市场,也是Savant最成熟和最重要的市场。
