目的了解急性白血病患者的红细胞输注情况,探讨影响急性白血病患者红细胞输注效果的因素。方法回顾性收集2017年12月—2018年12月在本院血液科治疗的87例急性白血病患者的资料,详细记录其初诊至1年内每次住院的红细胞输注情况,探讨年龄...目的了解急性白血病患者的红细胞输注情况,探讨影响急性白血病患者红细胞输注效果的因素。方法回顾性收集2017年12月—2018年12月在本院血液科治疗的87例急性白血病患者的资料,详细记录其初诊至1年内每次住院的红细胞输注情况,探讨年龄、性别、既往输血量等临床因素与红细胞输注有效率的关系。结果87例急性白血病患者1年内共计输注红细胞554次,输血有效次数为396次,输血有效率71.5%。单因素分析显示:男性患者的输血有效率明显低于女性(67.8%vs 75.9%,P<0.05);年龄不同输血有效率不同(≤15岁、16—40岁、41—60岁、>60岁的输血有效率分别为:80.5%、60.5%、72.8%、77.9%,P<0.05);既往输血量不同输血有效率亦不同(≤10 U vs 10—20 U vs>20 U:69.9%vs 67.4%vs 83.7%,P<0.05);输血间隔时间(≤10 d vs 10—30 d vs>30 d:66.8%vs 70.1%vs 83.2%,P<0.05)、骨髓抑制程度不同(77.5%vs 68.8%,P<0.05)输血有效率亦有明显差别。多因素Logistic回归分析显示:年龄、输血间隔时间和骨髓抑制程度是红细胞无效输注的独立影响因素。结论影响急性白血病患者红细胞输注效果的可能因素有:年龄、输血间隔时间、骨髓抑制程度、既往输血量及疾病的治疗控制情况。展开更多
Objective:To study the effect of the direct anti-human globulin test on the clinical efficacy of blood transfusion patients.Methods:52 transfused patients were selected for this study,of which 26 cases with positive d...Objective:To study the effect of the direct anti-human globulin test on the clinical efficacy of blood transfusion patients.Methods:52 transfused patients were selected for this study,of which 26 cases with positive direct anti-human globulin tests were included in the positive group,and another 26 cases with negative direct anti-human globulin tests were included in the negative group.The apparent efficacy of the patients in the two groups after blood transfusion was compared.Results:After blood transfusion,the apparent efficacy of the negative group was significantly higher,P<0.05;in the positive group,the proportion of the predominantly multi-antibody group was the highest;after blood transfusion,the post-transfusion apparent efficacy of the simple IgG group was higher than that of the multi-antibody group,P<0.05;comparing the intensity of the different antibodies resulted in the 1+group,and the 3+to 4+groups were significantly lower after blood transfusion,P<0.05.Conclusion:The use of the direct antiglobulin test in transfused patients showed that patients with positive results would have better clinical efficacy.Direct anti-human globulin tests will have an impact on the clinical efficacy of blood transfusion in patients with positive results,so it is very important to carry out a direct anti-human globulin test on blood transfusion patients.展开更多
文摘目的了解急性白血病患者的红细胞输注情况,探讨影响急性白血病患者红细胞输注效果的因素。方法回顾性收集2017年12月—2018年12月在本院血液科治疗的87例急性白血病患者的资料,详细记录其初诊至1年内每次住院的红细胞输注情况,探讨年龄、性别、既往输血量等临床因素与红细胞输注有效率的关系。结果87例急性白血病患者1年内共计输注红细胞554次,输血有效次数为396次,输血有效率71.5%。单因素分析显示:男性患者的输血有效率明显低于女性(67.8%vs 75.9%,P<0.05);年龄不同输血有效率不同(≤15岁、16—40岁、41—60岁、>60岁的输血有效率分别为:80.5%、60.5%、72.8%、77.9%,P<0.05);既往输血量不同输血有效率亦不同(≤10 U vs 10—20 U vs>20 U:69.9%vs 67.4%vs 83.7%,P<0.05);输血间隔时间(≤10 d vs 10—30 d vs>30 d:66.8%vs 70.1%vs 83.2%,P<0.05)、骨髓抑制程度不同(77.5%vs 68.8%,P<0.05)输血有效率亦有明显差别。多因素Logistic回归分析显示:年龄、输血间隔时间和骨髓抑制程度是红细胞无效输注的独立影响因素。结论影响急性白血病患者红细胞输注效果的可能因素有:年龄、输血间隔时间、骨髓抑制程度、既往输血量及疾病的治疗控制情况。
文摘Objective:To study the effect of the direct anti-human globulin test on the clinical efficacy of blood transfusion patients.Methods:52 transfused patients were selected for this study,of which 26 cases with positive direct anti-human globulin tests were included in the positive group,and another 26 cases with negative direct anti-human globulin tests were included in the negative group.The apparent efficacy of the patients in the two groups after blood transfusion was compared.Results:After blood transfusion,the apparent efficacy of the negative group was significantly higher,P<0.05;in the positive group,the proportion of the predominantly multi-antibody group was the highest;after blood transfusion,the post-transfusion apparent efficacy of the simple IgG group was higher than that of the multi-antibody group,P<0.05;comparing the intensity of the different antibodies resulted in the 1+group,and the 3+to 4+groups were significantly lower after blood transfusion,P<0.05.Conclusion:The use of the direct antiglobulin test in transfused patients showed that patients with positive results would have better clinical efficacy.Direct anti-human globulin tests will have an impact on the clinical efficacy of blood transfusion in patients with positive results,so it is very important to carry out a direct anti-human globulin test on blood transfusion patients.
