Objective:Urethral stricture disease after endo-urological treatment of benign prostatic hyperplasia(BPH)is a sparsely described complication.We describe management of five categories of these strictures in this retro...Objective:Urethral stricture disease after endo-urological treatment of benign prostatic hyperplasia(BPH)is a sparsely described complication.We describe management of five categories of these strictures in this retrospective observational case series.Methods:One hundred and twenty-one patients presenting with symptoms of bladder outflow obstruction after endo-urological intervention for BPH from February 2016 to March 2019 were evaluated.Among them,76 were eligible for this study and underwent reconstructive surgery.Preoperative and postoperative assessments were done with symptom scores,uroflowmetry,ultrasound for post-void residue,and urethrogram.Any intervention during follow-up was classed as a failure.The recurrence and 95%confidence interval for recurrence percentage were calculated.Results:The following five categories of patients were identified:Bulbo-membranous(33[43.4%]),navicular fossa(21[27.6%]),penile/peno-bulbar(8[10.5%]),bladder neck stenosis(6[7.9%]),and multiple locations(8[10.5%]).The average age was 69 years(range:60-84 years).Overall average symptom score,flow rate,and post-void residue changed from 21 to 7,6 mL/s to 19 mL/s,and 210 mL to 20 mL,respectively.The average follow-up was 34 months(range:12-58 months).Overall recurrence and complication rates were 10.5%and 9.2%,respectively.The recurrence in each category was seen in 3,1,2,1,and 1 patient,respectively.Overall 95% confidence interval for recurrence percentage was 4.66-19.69.Conclusion:Urethral stricture disease is a major long-term complication of endo-urological treatment of BPH.The bulbo-membranous strictures need continence preserving approach.Navicular fossa strictures require minimally invasive and cosmetic consideration.Peno-bulbar strictures require judicious use of grafts and flaps.Bladder neck stenosis in this cohort could be treated with endoscopic measures.Multiple locations need treatment based on their sites in single-stage as far as possible.展开更多
BACKGROUND Trans-urethral resection of prostate(TURP) is one of the most commonly performed operations in urology to treat bladder outflow obstruction(BOO) in men. TURP surgery is also a key for endo-urological traini...BACKGROUND Trans-urethral resection of prostate(TURP) is one of the most commonly performed operations in urology to treat bladder outflow obstruction(BOO) in men. TURP surgery is also a key for endo-urological training in the British National Health Service(NHS) for training junior urologists. The working hypothesis is that prostate resection speed(PRS) in the context of bipolar TURP surgery, is not a key factor in major complication rates or broad patient outcomes at 3 mo after surgery, and therefore supervising consultants should not focus primarily on resection speed when teaching TURP.AIM To investigate objective differences in consultants vs trainees PRS and whether PRS affected complication rates/outcomes after TURP.METHODS Retrospective descriptive study analyzing patient case-notes, operative and electronic records, study undertaken at Burton Queen's Hospital NHS Foundation Trust, United Kingdom, a secondary care centre in the public sector of the NHS. Participants included: all Bipolar TURPs undertaken between13/04/2016 and 27/06/2017. Exclusions: patients undergoing concomitant operations or where intra-operative equipment problems occurred. Resected prostate(g), operative time, post-operative complications and outcomes at 3-mo were obtained from electronic records. Clavien-Dindo Grade II complications or above considered significant. Binary successful yes/no outcome at 3-mo after surgery included both patients who reported moderate to significant symptom improvement, or being catheter-free for those catheterized before TURP.RESULTS157 patients were identified. After exclusion a total of 125 patients were included from analysis. The mean PRS for trainees(0.34 g/min) was found to be lower than the mean PRS for consultants(0.41 g/min). The operating urologist's PRS was not observed to be related to the number of TURPs that they performed during the period of the study. The trainee vs consultant means post-operative success rates(86.5% vs 90.5%) were comparable. The Trainees' patients did not suffer any s展开更多
目的:探讨腰硬联合麻醉(combined spinal and epidural anesthesia,CSEA)用于老年患者经尿道前列腺电切术(TURP)的可行性。方法:选择拟行TURP术的老年男性患者共68例,随机分为腰硬联合麻醉组(CSEA组)和硬膜外麻醉组(CEA组),每组34例;CES...目的:探讨腰硬联合麻醉(combined spinal and epidural anesthesia,CSEA)用于老年患者经尿道前列腺电切术(TURP)的可行性。方法:选择拟行TURP术的老年男性患者共68例,随机分为腰硬联合麻醉组(CSEA组)和硬膜外麻醉组(CEA组),每组34例;CESA组用针内针法于L2~3行刺,蛛网膜下腔注入0.75%布比卡因2mL与10%葡萄糖1mL混合液(1~2)mL(5~10)mg,并硬膜外腔置管;CEA组L2~3间隙行硬膜外腔穿刺并置管。两组硬膜外腔均选用1.33%利多卡因与0.25%布比卡因混合液。常规监测BP、ECG、SpO2并记录,记录麻醉起效和镇痛效果,记录术中并发症如低血压、心动过缓、呼吸抑制等发生情况。结果:麻醉起效时间,CSEA组为(6.5±0.8)min,CEA组为(12.9±2.6)min,(P<0.01);麻醉效果优级者CSEA组有34例(占100%),CEA组有28例(占82%),(P<0.05);CEA组麻醉后30minSBP较麻醉前下降明显(P<0.05),而CSEA组则麻醉后10minSBP较麻醉前下降明显(P<0.05);SBP及HR最低值组...展开更多
目的:探讨经尿道钬激光前列腺剜除术(trans-urethral holmium laser enucleation of prostate,HoLEP)对老年良性前列腺增生(benign prostatic hyperplasia,BPH)患者的影响。方法:选取2021年6月—2022年6月大方县人民医院收治的92例老年...目的:探讨经尿道钬激光前列腺剜除术(trans-urethral holmium laser enucleation of prostate,HoLEP)对老年良性前列腺增生(benign prostatic hyperplasia,BPH)患者的影响。方法:选取2021年6月—2022年6月大方县人民医院收治的92例老年BPH患者作为研究对象。根据随机数表法将其分为A组和B组,各46例。A组给予经尿道前列腺切除术(transurethral resection of prostate,TURP),B组给予HoLEP。比较两组术前、术后1个月相关指标、前列腺症状、生命质量及并发症分级。结果:术后1个月,两组最大尿流率(maximum urinary flow rate,Qmax)水平均提高,前列腺体积及前列腺特异性抗原(prostate specific antigen,PSA)水平均下降,B组Qmax水平高于A组,前列腺体积及PSA水平均低于A组,差异有统计学意义(P<0.05)。术后1个月,两组国际前列腺症状评分(international prostate symptom score,IPSS)评分降低,生命质量测定量表(quality of life instruments for chronic diseases-benign prostatic hyperplasia,QLICD-BPH)评分升高,B组IPSS评分低于A组,QLICD-BPH评分高于A组,差异有统计学意义(P<0.05)。B组Ⅱ级及Ⅳ级并发症发生率均低于A组,差异有统计学意义(P<0.05)。结论:HoLEP能够增加老年BPH患者Qmax,缩小其前列腺体积,缓解患者前列腺症状,提高其生命质量,同时有助于减少术后并发症。展开更多
文摘Objective:Urethral stricture disease after endo-urological treatment of benign prostatic hyperplasia(BPH)is a sparsely described complication.We describe management of five categories of these strictures in this retrospective observational case series.Methods:One hundred and twenty-one patients presenting with symptoms of bladder outflow obstruction after endo-urological intervention for BPH from February 2016 to March 2019 were evaluated.Among them,76 were eligible for this study and underwent reconstructive surgery.Preoperative and postoperative assessments were done with symptom scores,uroflowmetry,ultrasound for post-void residue,and urethrogram.Any intervention during follow-up was classed as a failure.The recurrence and 95%confidence interval for recurrence percentage were calculated.Results:The following five categories of patients were identified:Bulbo-membranous(33[43.4%]),navicular fossa(21[27.6%]),penile/peno-bulbar(8[10.5%]),bladder neck stenosis(6[7.9%]),and multiple locations(8[10.5%]).The average age was 69 years(range:60-84 years).Overall average symptom score,flow rate,and post-void residue changed from 21 to 7,6 mL/s to 19 mL/s,and 210 mL to 20 mL,respectively.The average follow-up was 34 months(range:12-58 months).Overall recurrence and complication rates were 10.5%and 9.2%,respectively.The recurrence in each category was seen in 3,1,2,1,and 1 patient,respectively.Overall 95% confidence interval for recurrence percentage was 4.66-19.69.Conclusion:Urethral stricture disease is a major long-term complication of endo-urological treatment of BPH.The bulbo-membranous strictures need continence preserving approach.Navicular fossa strictures require minimally invasive and cosmetic consideration.Peno-bulbar strictures require judicious use of grafts and flaps.Bladder neck stenosis in this cohort could be treated with endoscopic measures.Multiple locations need treatment based on their sites in single-stage as far as possible.
文摘BACKGROUND Trans-urethral resection of prostate(TURP) is one of the most commonly performed operations in urology to treat bladder outflow obstruction(BOO) in men. TURP surgery is also a key for endo-urological training in the British National Health Service(NHS) for training junior urologists. The working hypothesis is that prostate resection speed(PRS) in the context of bipolar TURP surgery, is not a key factor in major complication rates or broad patient outcomes at 3 mo after surgery, and therefore supervising consultants should not focus primarily on resection speed when teaching TURP.AIM To investigate objective differences in consultants vs trainees PRS and whether PRS affected complication rates/outcomes after TURP.METHODS Retrospective descriptive study analyzing patient case-notes, operative and electronic records, study undertaken at Burton Queen's Hospital NHS Foundation Trust, United Kingdom, a secondary care centre in the public sector of the NHS. Participants included: all Bipolar TURPs undertaken between13/04/2016 and 27/06/2017. Exclusions: patients undergoing concomitant operations or where intra-operative equipment problems occurred. Resected prostate(g), operative time, post-operative complications and outcomes at 3-mo were obtained from electronic records. Clavien-Dindo Grade II complications or above considered significant. Binary successful yes/no outcome at 3-mo after surgery included both patients who reported moderate to significant symptom improvement, or being catheter-free for those catheterized before TURP.RESULTS157 patients were identified. After exclusion a total of 125 patients were included from analysis. The mean PRS for trainees(0.34 g/min) was found to be lower than the mean PRS for consultants(0.41 g/min). The operating urologist's PRS was not observed to be related to the number of TURPs that they performed during the period of the study. The trainee vs consultant means post-operative success rates(86.5% vs 90.5%) were comparable. The Trainees' patients did not suffer any s
文摘目的:探讨腰硬联合麻醉(combined spinal and epidural anesthesia,CSEA)用于老年患者经尿道前列腺电切术(TURP)的可行性。方法:选择拟行TURP术的老年男性患者共68例,随机分为腰硬联合麻醉组(CSEA组)和硬膜外麻醉组(CEA组),每组34例;CESA组用针内针法于L2~3行刺,蛛网膜下腔注入0.75%布比卡因2mL与10%葡萄糖1mL混合液(1~2)mL(5~10)mg,并硬膜外腔置管;CEA组L2~3间隙行硬膜外腔穿刺并置管。两组硬膜外腔均选用1.33%利多卡因与0.25%布比卡因混合液。常规监测BP、ECG、SpO2并记录,记录麻醉起效和镇痛效果,记录术中并发症如低血压、心动过缓、呼吸抑制等发生情况。结果:麻醉起效时间,CSEA组为(6.5±0.8)min,CEA组为(12.9±2.6)min,(P<0.01);麻醉效果优级者CSEA组有34例(占100%),CEA组有28例(占82%),(P<0.05);CEA组麻醉后30minSBP较麻醉前下降明显(P<0.05),而CSEA组则麻醉后10minSBP较麻醉前下降明显(P<0.05);SBP及HR最低值组...
文摘目的:探讨经尿道钬激光前列腺剜除术(trans-urethral holmium laser enucleation of prostate,HoLEP)对老年良性前列腺增生(benign prostatic hyperplasia,BPH)患者的影响。方法:选取2021年6月—2022年6月大方县人民医院收治的92例老年BPH患者作为研究对象。根据随机数表法将其分为A组和B组,各46例。A组给予经尿道前列腺切除术(transurethral resection of prostate,TURP),B组给予HoLEP。比较两组术前、术后1个月相关指标、前列腺症状、生命质量及并发症分级。结果:术后1个月,两组最大尿流率(maximum urinary flow rate,Qmax)水平均提高,前列腺体积及前列腺特异性抗原(prostate specific antigen,PSA)水平均下降,B组Qmax水平高于A组,前列腺体积及PSA水平均低于A组,差异有统计学意义(P<0.05)。术后1个月,两组国际前列腺症状评分(international prostate symptom score,IPSS)评分降低,生命质量测定量表(quality of life instruments for chronic diseases-benign prostatic hyperplasia,QLICD-BPH)评分升高,B组IPSS评分低于A组,QLICD-BPH评分高于A组,差异有统计学意义(P<0.05)。B组Ⅱ级及Ⅳ级并发症发生率均低于A组,差异有统计学意义(P<0.05)。结论:HoLEP能够增加老年BPH患者Qmax,缩小其前列腺体积,缓解患者前列腺症状,提高其生命质量,同时有助于减少术后并发症。
