The purpose of this paper is to present the results of investigations on quasi-one-dimensional organic crystals of tetrathiotetracene-tetracyanoquinodi- methane (TTT(TCNQ)<sub>2</sub>) from the prospective...The purpose of this paper is to present the results of investigations on quasi-one-dimensional organic crystals of tetrathiotetracene-tetracyanoquinodi- methane (TTT(TCNQ)<sub>2</sub>) from the prospective of thermoelectric applications. The calculations were performed after analytical expressions, obtained in the frame of a physical model, more detailed than the model presented earlier by authors. The main Hamiltonian of the model includes the electronic and phonon part, electron-phonon interactions and the impurity scattering term. In order to estimate the electric charge transport between the molecular chains, the physical model was upgraded to the so-called three-dimen- sional (3D) physical model. Numeric computations were performed to determine the electrical conductivity, Seebeck coefficient, thermal conductivity, thermoelectric power factor and thermoelectric figure-of-merit as a function on charge carrier concentrations, temperatures and impurity concentrations. A detailed analysis of charge-lattice interaction, consisting of the exploration of the Peierls structural transition in TCNQ molecular chains of TTT(TCNQ)<sub>2</sub> was performed. As result, the critical transition temperature was determined. The dispersion of renormalized phonons was examined in detail.展开更多
A reduced model is proposed and analyzed for the simulation of vortexinduced vibrations （VIVs） for turbine blades. A rotating blade is modelled as a uniform cantilever beam, while a van der Pol oscillator is used to...A reduced model is proposed and analyzed for the simulation of vortexinduced vibrations （VIVs） for turbine blades. A rotating blade is modelled as a uniform cantilever beam, while a van der Pol oscillator is used to represent the time-varying characteristics of the vortex shedding, which interacts with the equations of motion for the blade to simulate the fluid-structure interaction. The action for the structural motion on the fluid is considered as a linear inertia coupling. The nonlinear characteristics for the dynamic responses are investigated with the multiple scale method, and the modulation equations are derived. The transition set consisting of the bifurcation set and the hystere- sis set is constructed by the singularity theory and the effects of the system parameters, such as the van der Pol damping. The coupling parameter on the equilibrium solutions is analyzed. The frequency-response curves are obtained, and the stabilities are determined by the Routh-Hurwitz criterion. The phenomena including the saddle-node and Hopf bifurcations are found to occur under certain parameter values. A direct numerical method is used to analyze the dynamic characteristics for the original system and verify the va- lidity of the multiple scale method. The results indicate that the new coupled model is useful in explaining the rich dynamic response characteristics such as possible bifurcation phenomena in the VIVs.展开更多
The SCR (Software Cost Reduction) requirements method is aneffective method for specifying software system requirements. This paper presents aformal model analyzing SCR-style requirements. The analysis model mainly ap...The SCR (Software Cost Reduction) requirements method is aneffective method for specifying software system requirements. This paper presents aformal model analyzing SCR-style requirements. The analysis model mainly appliesstate translation rules, semantic computing rules and attributes to define formal se-mantics of a tabular notation in the SCR requirements method, and may be used toanalyze requirements specifications to be specified by the SCR requirements method.Using a simple example, this paper introduces how to analyze consistency and com-pleteness of requirements specifications.展开更多
Resource reconstruction algorithms are studied in this paper to solve the problem of resource on-demand allocation and improve the efficiency of resource utilization in virtual computing resource pool. Based on the id...Resource reconstruction algorithms are studied in this paper to solve the problem of resource on-demand allocation and improve the efficiency of resource utilization in virtual computing resource pool. Based on the idea of resource virtualization and the analysis of the resource status transition, the resource allocation process and the necessity of resource reconstruction are presented, l^esource reconstruction algorithms are designed to determine the resource reconstruction types, and it is shown that they can achieve the goal of resource on-demand allocation through three methodologies： resource combination, resource split, and resource random adjustment. The effects that the resource users have on the resource reconstruction results, the deviation between resources and requirements, and the uniformity of resource distribution are studied by three experiments. The experiments show that resource reconstruction has a close relationship with resource requirements, but it is not the same with current distribution of resources. The algorithms can complete the resource adjustment with a lower cost and form the logic resources to match the demands of resource users easily.展开更多
Polarized micro-Raman spectra of a 0.65PbMgl/3Nb2/303 0.35PbTiO3 （0.65PMN-0.35PT） single crystal poled in the [001] direction are obtained in a wide frequency range （50 2000 cm^-1） at different temperatures. The b...Polarized micro-Raman spectra of a 0.65PbMgl/3Nb2/303 0.35PbTiO3 （0.65PMN-0.35PT） single crystal poled in the [001] direction are obtained in a wide frequency range （50 2000 cm^-1） at different temperatures. The best fit to the Raman spectrum at 77 K is achieved using 17 Lorenzians to convolute into it, and this is proved to be a reasonable fit. According to the group theory and selection rules of overtone and combinational modes, apart from the seven Raman modes that are from first-order Raman scattering, the remaining ones are attributed to being from second-order Raman scattering. A comparison between the experimental results and theoretical predictions shows that they are in satisfactory agreement with each other. Our results indicate that at 77 K the sample belongs to the rhombohedral symmetry with the C^53v（R3m） space group （Z = 1）. In our study, on heating, the 0.65PMN 0.35PT single crystal undergoes a rhombohedral → tetragonal → cubic phase transition sequence. The two phase transitions occur at 340 and 440 K, which correspond to the disappearance of the soft mode near 106 cm-1 recorded in VV polarization and the vanishing of the band around 780 cm^-1 in VH polarization, respectively.展开更多
Objective Despite microRNA （miR-200b） being proved to promote the proliferation of colorectal cancer （CRC） cells, the relationship between miR-200b and epithelial-mesenchymal transition （EMT） of CRC cells remain...Objective Despite microRNA （miR-200b） being proved to promote the proliferation of colorectal cancer （CRC） cells, the relationship between miR-200b and epithelial-mesenchymal transition （EMT） of CRC cells remains poorly understood. The aim of the study was to investigate the relationship between miR-200b and EMT during CRC cell migration. Methods The effect of miR-200b on EMT-associated markers E-cadherin and vimentin was evaluated by western blot in CRC cells （SW620 and HT-29） by treatment with miR-200b mimics and inhibitors. A lucifer- ase reporter assay was employed to detect downstream targets of miR-200b. Transwell migration assays were used to detect CRC cell migration. Results Westem blots revealed that treatment with miR-200b mimics led to up-regulation of E-cadherin and down-regulation of vimentin, metalloproteinase （MMP）-9, and MMP-2, whereas treatment with miR- 200b inhibitor exhibited opposite effects on expression of E-cadherin and vimentin. Luciferase reporter assays demonstrated that RhoE （RND3） was targeted by miR-200b. Two predicted target sites of miR-200b were present in the 3＇-UTR of RhoE. Predicted target site 1 was from nucleotides 1584 to 1591, and site 2 was from nucleotides 1729 to 1735. RhoE knockdown cell lines were also established to investigate the impact of RhoE and miR-200b on EMT and cell migration. RhoE knockdown enhanced the effect of miR- 200b mimics, up-regulating E-cadherin and down-regulating vimentin. RhoE knockdown also inhibited cell migration. Furthermore, miR-200b mimic treatment further promoted the inhibitory effect of RhoE knock- down on cell migration.展开更多
Cuticular proteins(CPs)are critical components of the insect cuticle and play important roles in maintaining normal insect development and defense against various environmental stresses.The oriental fruit fly(Bactroce...Cuticular proteins(CPs)are critical components of the insect cuticle and play important roles in maintaining normal insect development and defense against various environmental stresses.The oriental fruit fly(Bactrocera dorsalis)is one of the most destructive pests worldwide,and its eight CPs analogous to peritrophin 3(BdCPAP3)family genes have been identified in our prev ious study.In the present study,we further explored the possible roles of CPAP3 genes in B.dorsalis development.Each sequence of BdCPAP3 genes contained three conserved ChtBD2(chitin-binding)domains.Spatial and temporal expression patterns revealed that the four BdCPAP3 genes(BdCPAP3-AI,B,E,and E2)might play important roles in larval pupariation of B.dorsalis.Moreover,treatment with a juvenile hormone analog(methoprene)significantly restricted expression of these four CPAP3 genes,whereas treatment with 20-hydroxy-ecdysone induced expression.The RNA interference(RNAi)results revealed that down-regulated CPAP3 genes led to signif-icant delay of pupariation,and injection of dsBdCPAP3-E into 5-d-old B.dorsalis larvae caused approximately 40%mortality.Interestingly,we also confirmed that BdCPAP3-D2 was involved in B.dorsalis ovarian development.This study showed that some specific CP4P3 genes had crucial roles in B.dorsalis development,and these CP genes could be used as potential targets to control this pest via RNAi.展开更多
Molecular models of pristine, functionalized and cross-linked graphene sheet/polymer composites are developed. Temperature cooling processes are conducted to examine the improve-ment of glass transition temperature of...Molecular models of pristine, functionalized and cross-linked graphene sheet/polymer composites are developed. Temperature cooling processes are conducted to examine the improve-ment of glass transition temperature of cross-linked graphene sheet/polymer composites using molecular dynamics simulations. The results show that increases of about 12.2% and 8.9% in the glass transition temperature of cross-linked graphene sheet/polymer composites are obtained, respectively, than those of the pristine and functionalized graphene sheet/polymer composites. In order to reveal the enhanced thermal properties from atomic views, the interfacial interaction energy and radius distribution function between the graphene sheets and the polymer matrix, the mean square displacement variations and the free volume of polymer composites are examined and discussed.展开更多
Shizitan in Jixian County, Shanxi Province, is a site of transitional period from Paleolithic to Neolithic. The dating and the sporopollen analysis show that the middle reaches of the Yellow River where the site is lo...Shizitan in Jixian County, Shanxi Province, is a site of transitional period from Paleolithic to Neolithic. The dating and the sporopollen analysis show that the middle reaches of the Yellow River where the site is located had been maintaining a steppe environment during 35.1-9.4 kaBP, in which, 35.1-17 kaBP belonged to the last glacial. With cold and dry climate, this period featured a desert steppe environment. In the late of this period, the area had a cold and half-humid steppe environment. The 17.0-11.9 kaBP belonged to the early- and mid-period of the last deglaciation. Mild and half-arid steppe alternates with mild and half-arid steppe, with a small amount of deciduous broadleaf species. During the period of 11.9-10.5 kaBP, cold and dry glacial climate appeared once more, featuring a desert steppe environment. During 10.5-9.4 kaBP, it is mild and half-arid, and later transited toward warm and half-humid. The early phase of this period featured a steppe environment and the later transited into a展开更多
文摘The purpose of this paper is to present the results of investigations on quasi-one-dimensional organic crystals of tetrathiotetracene-tetracyanoquinodi- methane (TTT(TCNQ)<sub>2</sub>) from the prospective of thermoelectric applications. The calculations were performed after analytical expressions, obtained in the frame of a physical model, more detailed than the model presented earlier by authors. The main Hamiltonian of the model includes the electronic and phonon part, electron-phonon interactions and the impurity scattering term. In order to estimate the electric charge transport between the molecular chains, the physical model was upgraded to the so-called three-dimen- sional (3D) physical model. Numeric computations were performed to determine the electrical conductivity, Seebeck coefficient, thermal conductivity, thermoelectric power factor and thermoelectric figure-of-merit as a function on charge carrier concentrations, temperatures and impurity concentrations. A detailed analysis of charge-lattice interaction, consisting of the exploration of the Peierls structural transition in TCNQ molecular chains of TTT(TCNQ)<sub>2</sub> was performed. As result, the critical transition temperature was determined. The dispersion of renormalized phonons was examined in detail.
基金Project supported by the National Basic Research Program of China(973 Program)(No.2015CB057405)the National Natural Science Foundation of China(No.11372082)the State Scholarship Fund of China Scholarship Council(CSC)(2014)
文摘A reduced model is proposed and analyzed for the simulation of vortexinduced vibrations （VIVs） for turbine blades. A rotating blade is modelled as a uniform cantilever beam, while a van der Pol oscillator is used to represent the time-varying characteristics of the vortex shedding, which interacts with the equations of motion for the blade to simulate the fluid-structure interaction. The action for the structural motion on the fluid is considered as a linear inertia coupling. The nonlinear characteristics for the dynamic responses are investigated with the multiple scale method, and the modulation equations are derived. The transition set consisting of the bifurcation set and the hystere- sis set is constructed by the singularity theory and the effects of the system parameters, such as the van der Pol damping. The coupling parameter on the equilibrium solutions is analyzed. The frequency-response curves are obtained, and the stabilities are determined by the Routh-Hurwitz criterion. The phenomena including the saddle-node and Hopf bifurcations are found to occur under certain parameter values. A direct numerical method is used to analyze the dynamic characteristics for the original system and verify the va- lidity of the multiple scale method. The results indicate that the new coupled model is useful in explaining the rich dynamic response characteristics such as possible bifurcation phenomena in the VIVs.
文摘The SCR (Software Cost Reduction) requirements method is aneffective method for specifying software system requirements. This paper presents aformal model analyzing SCR-style requirements. The analysis model mainly appliesstate translation rules, semantic computing rules and attributes to define formal se-mantics of a tabular notation in the SCR requirements method, and may be used toanalyze requirements specifications to be specified by the SCR requirements method.Using a simple example, this paper introduces how to analyze consistency and com-pleteness of requirements specifications.
基金supported by National High Technology Research and Development Program of China (863 Program)(No. 2007AA010305)the Excellent Doctor Degree Dissertation Fund of Xi an University of Technology (No. 102-211007)
文摘Resource reconstruction algorithms are studied in this paper to solve the problem of resource on-demand allocation and improve the efficiency of resource utilization in virtual computing resource pool. Based on the idea of resource virtualization and the analysis of the resource status transition, the resource allocation process and the necessity of resource reconstruction are presented, l^esource reconstruction algorithms are designed to determine the resource reconstruction types, and it is shown that they can achieve the goal of resource on-demand allocation through three methodologies： resource combination, resource split, and resource random adjustment. The effects that the resource users have on the resource reconstruction results, the deviation between resources and requirements, and the uniformity of resource distribution are studied by three experiments. The experiments show that resource reconstruction has a close relationship with resource requirements, but it is not the same with current distribution of resources. The algorithms can complete the resource adjustment with a lower cost and form the logic resources to match the demands of resource users easily.
基金Project supported by the National Natural Science Foundation of China(Grant Nos.10674171 and 10874236)
文摘Polarized micro-Raman spectra of a 0.65PbMgl/3Nb2/303 0.35PbTiO3 （0.65PMN-0.35PT） single crystal poled in the [001] direction are obtained in a wide frequency range （50 2000 cm^-1） at different temperatures. The best fit to the Raman spectrum at 77 K is achieved using 17 Lorenzians to convolute into it, and this is proved to be a reasonable fit. According to the group theory and selection rules of overtone and combinational modes, apart from the seven Raman modes that are from first-order Raman scattering, the remaining ones are attributed to being from second-order Raman scattering. A comparison between the experimental results and theoretical predictions shows that they are in satisfactory agreement with each other. Our results indicate that at 77 K the sample belongs to the rhombohedral symmetry with the C^53v（R3m） space group （Z = 1）. In our study, on heating, the 0.65PMN 0.35PT single crystal undergoes a rhombohedral → tetragonal → cubic phase transition sequence. The two phase transitions occur at 340 and 440 K, which correspond to the disappearance of the soft mode near 106 cm-1 recorded in VV polarization and the vanishing of the band around 780 cm^-1 in VH polarization, respectively.
文摘Objective Despite microRNA （miR-200b） being proved to promote the proliferation of colorectal cancer （CRC） cells, the relationship between miR-200b and epithelial-mesenchymal transition （EMT） of CRC cells remains poorly understood. The aim of the study was to investigate the relationship between miR-200b and EMT during CRC cell migration. Methods The effect of miR-200b on EMT-associated markers E-cadherin and vimentin was evaluated by western blot in CRC cells （SW620 and HT-29） by treatment with miR-200b mimics and inhibitors. A lucifer- ase reporter assay was employed to detect downstream targets of miR-200b. Transwell migration assays were used to detect CRC cell migration. Results Westem blots revealed that treatment with miR-200b mimics led to up-regulation of E-cadherin and down-regulation of vimentin, metalloproteinase （MMP）-9, and MMP-2, whereas treatment with miR- 200b inhibitor exhibited opposite effects on expression of E-cadherin and vimentin. Luciferase reporter assays demonstrated that RhoE （RND3） was targeted by miR-200b. Two predicted target sites of miR-200b were present in the 3＇-UTR of RhoE. Predicted target site 1 was from nucleotides 1584 to 1591, and site 2 was from nucleotides 1729 to 1735. RhoE knockdown cell lines were also established to investigate the impact of RhoE and miR-200b on EMT and cell migration. RhoE knockdown enhanced the effect of miR- 200b mimics, up-regulating E-cadherin and down-regulating vimentin. RhoE knockdown also inhibited cell migration. Furthermore, miR-200b mimic treatment further promoted the inhibitory effect of RhoE knock- down on cell migration.
基金the National Key Research and.Development Program(2017YFD0202002)the National Natural Sciences Foundation(31872031,31672030)+3 种基金the Fundamental Research Funds for the Central Universities,China(2362015xk04,XDJK2018B041)the Fundamental and Advanced Research Projects of Chongqing(cstc2015jcyjA80009)the earmarked fund for the Modern Agroindustry(Cit-rus)Technology Research System of China(CARS-26)the l11 Project(B 18044)。
文摘Cuticular proteins(CPs)are critical components of the insect cuticle and play important roles in maintaining normal insect development and defense against various environmental stresses.The oriental fruit fly(Bactrocera dorsalis)is one of the most destructive pests worldwide,and its eight CPs analogous to peritrophin 3(BdCPAP3)family genes have been identified in our prev ious study.In the present study,we further explored the possible roles of CPAP3 genes in B.dorsalis development.Each sequence of BdCPAP3 genes contained three conserved ChtBD2(chitin-binding)domains.Spatial and temporal expression patterns revealed that the four BdCPAP3 genes(BdCPAP3-AI,B,E,and E2)might play important roles in larval pupariation of B.dorsalis.Moreover,treatment with a juvenile hormone analog(methoprene)significantly restricted expression of these four CPAP3 genes,whereas treatment with 20-hydroxy-ecdysone induced expression.The RNA interference(RNAi)results revealed that down-regulated CPAP3 genes led to signif-icant delay of pupariation,and injection of dsBdCPAP3-E into 5-d-old B.dorsalis larvae caused approximately 40%mortality.Interestingly,we also confirmed that BdCPAP3-D2 was involved in B.dorsalis ovarian development.This study showed that some specific CP4P3 genes had crucial roles in B.dorsalis development,and these CP genes could be used as potential targets to control this pest via RNAi.
文摘Molecular models of pristine, functionalized and cross-linked graphene sheet/polymer composites are developed. Temperature cooling processes are conducted to examine the improve-ment of glass transition temperature of cross-linked graphene sheet/polymer composites using molecular dynamics simulations. The results show that increases of about 12.2% and 8.9% in the glass transition temperature of cross-linked graphene sheet/polymer composites are obtained, respectively, than those of the pristine and functionalized graphene sheet/polymer composites. In order to reveal the enhanced thermal properties from atomic views, the interfacial interaction energy and radius distribution function between the graphene sheets and the polymer matrix, the mean square displacement variations and the free volume of polymer composites are examined and discussed.
基金This work was supported by the National Natural Science Foundation of China (Grant Nos. 49771074 and 49831080).
文摘Shizitan in Jixian County, Shanxi Province, is a site of transitional period from Paleolithic to Neolithic. The dating and the sporopollen analysis show that the middle reaches of the Yellow River where the site is located had been maintaining a steppe environment during 35.1-9.4 kaBP, in which, 35.1-17 kaBP belonged to the last glacial. With cold and dry climate, this period featured a desert steppe environment. In the late of this period, the area had a cold and half-humid steppe environment. The 17.0-11.9 kaBP belonged to the early- and mid-period of the last deglaciation. Mild and half-arid steppe alternates with mild and half-arid steppe, with a small amount of deciduous broadleaf species. During the period of 11.9-10.5 kaBP, cold and dry glacial climate appeared once more, featuring a desert steppe environment. During 10.5-9.4 kaBP, it is mild and half-arid, and later transited toward warm and half-humid. The early phase of this period featured a steppe environment and the later transited into a
