Background:As part of an ongoing program that aims to use early detection and timely treatment to improve the control of echinococcosis,especially in younger age groups,we undertook a series of active surveys among Qi...Background:As part of an ongoing program that aims to use early detection and timely treatment to improve the control of echinococcosis,especially in younger age groups,we undertook a series of active surveys among Qinghai-Tibetan children in the Qinghai Province of Northwestern China in 2011 and 2012.The significant outcomes that resulted from this study emphasize the need to draw attention to echinococcosis,both alveolar echinococcosis(AE)and cystic echinococcosis(CE),so that policy development is promoted and suitable avenues for control are identified in the highly endemic areas on the Tibetan Plateau.Methods:A total of 19629 primary school students,aged 6-18 years,with a dominant Tibetan background underwent abdominal ultrasound examination,and 86.4%of the compliant students donated 2-5 ml of venous blood for serological tests.All the abnormal ultrasound results were recorded.If identified as echinococcosis,the disease lesion was assessed according to the WHO-Informal Working Group on Echinococcosis(WHO-IWGE)classification for AE and CE.Among the surveyed students,the prevalence by school was compared among geo-locations,sex and age groups.The clinical image presentations were analyzed according to lesion number,size,the location in the liver and the classification stage.Statistical significance was set at P-value<0.05 for comparisons among groups.Results:A total of 341 students(1.7%)were identified by ultrasound as having either CE(119,0.6%)or AE(222,1.1%).The highest prevalence rates of childhood AE cases occurred in the Tehetu(12.1%)and Moba(11.8%)townships in Dari County.There was a high seropositive rate(37.0%)and a heterogeneous distribution of cases,with a prevalence ranged from 0 to 12.1%for AE and 0-2.9%for CE.Moreover,the seropositive rate ranged from 0.7-45.1%across different schools.Conclusions:The high prevalence of echinococcosis in Qinghai-Tibetan primary school students reflects a lack of knowledge about Echinococcus spp.transmission.The combination of systematic education for children and re展开更多
<strong>Background:</strong> Henoch Schonlein Purpura (HSP) is a common immune-related allergic disease in children. It is very important to understand the clinical features of this disease for doctors. &l...<strong>Background:</strong> Henoch Schonlein Purpura (HSP) is a common immune-related allergic disease in children. It is very important to understand the clinical features of this disease for doctors. <strong>Objective:</strong> To explore the clinical efficacy of glucocorticoids in the treatment of HSP in Tibetan children at high altitude, and to analyze the possible causes of HSP in children at high altitude. The risk factors of the disease provide a reference for the treatment of HSP in children in high altitude areas. <strong>Methods:</strong> Selecting January 2015 to November 2020, 88 children diagnosed with Henoch-Schonlein Purpura in the outpatient and inpatient departments of the People’s Hospital of Bomi County, Tibet Autonomous Region were the subjects of the study. Its gender, age of onset, season of onset, predisposing factors, allergy history, first symptoms, clinical manifestations, laboratory examinations, etc., perform retrospective analysis. <strong>Results: </strong>Among 88 children with allergic purpura, 55 were boys, accounting for 62.5%, and 33 were girls, accounting for 37.5%. Men have more cases than women. All have clinical manifestations of purpura of the skin, among which 35 cases have obvious triggers, of which the above there were 26 cases of respiratory infections, 6 cases of dietary factors, and 3 cases of contact with allergic substances. Simple skin type: 18 cases, accounting for 20.45%;Abdominal type: 6 cases, accounting for 6.82%;2 male cases, accounting for 33.33%;4 female cases, accounting for 66.67%;Articular type: 8 cases, accounting for 33.33%;Renal type: 2 cases, accounting for 2.27%;54 cases of mixed type, accounting for 61.36%. After glucocorticoids, the rashes disappeared, no any adverse reactions. <strong>Conclusion:</strong> Allergic purpura in children is more common in school-age children, and upper respiratory tract infection is the main predisposing factor. Skin purpura is the main clinical manifestation, often associated with lower extremity joint swelling a展开更多
Morbidity associated with conjunctivitis is higher in developing countries,particularly among children,because of the poorer standards of living（Azari and Barney,2013;Yetman and Coody,1997）.Presently,little is known...Morbidity associated with conjunctivitis is higher in developing countries,particularly among children,because of the poorer standards of living（Azari and Barney,2013;Yetman and Coody,1997）.Presently,little is known regarding the microorganisms that cause conjunctivitis in the remote area of Chinese Tibet.In particular,it is difficult to monitor and control the occurrence of conjunctivitis in children from this area.展开更多
基金Our research was supported by the Natural Science Foundation of Qinghai,China for this project(No.2015-HZ-809).
文摘Background:As part of an ongoing program that aims to use early detection and timely treatment to improve the control of echinococcosis,especially in younger age groups,we undertook a series of active surveys among Qinghai-Tibetan children in the Qinghai Province of Northwestern China in 2011 and 2012.The significant outcomes that resulted from this study emphasize the need to draw attention to echinococcosis,both alveolar echinococcosis(AE)and cystic echinococcosis(CE),so that policy development is promoted and suitable avenues for control are identified in the highly endemic areas on the Tibetan Plateau.Methods:A total of 19629 primary school students,aged 6-18 years,with a dominant Tibetan background underwent abdominal ultrasound examination,and 86.4%of the compliant students donated 2-5 ml of venous blood for serological tests.All the abnormal ultrasound results were recorded.If identified as echinococcosis,the disease lesion was assessed according to the WHO-Informal Working Group on Echinococcosis(WHO-IWGE)classification for AE and CE.Among the surveyed students,the prevalence by school was compared among geo-locations,sex and age groups.The clinical image presentations were analyzed according to lesion number,size,the location in the liver and the classification stage.Statistical significance was set at P-value<0.05 for comparisons among groups.Results:A total of 341 students(1.7%)were identified by ultrasound as having either CE(119,0.6%)or AE(222,1.1%).The highest prevalence rates of childhood AE cases occurred in the Tehetu(12.1%)and Moba(11.8%)townships in Dari County.There was a high seropositive rate(37.0%)and a heterogeneous distribution of cases,with a prevalence ranged from 0 to 12.1%for AE and 0-2.9%for CE.Moreover,the seropositive rate ranged from 0.7-45.1%across different schools.Conclusions:The high prevalence of echinococcosis in Qinghai-Tibetan primary school students reflects a lack of knowledge about Echinococcus spp.transmission.The combination of systematic education for children and re
文摘<strong>Background:</strong> Henoch Schonlein Purpura (HSP) is a common immune-related allergic disease in children. It is very important to understand the clinical features of this disease for doctors. <strong>Objective:</strong> To explore the clinical efficacy of glucocorticoids in the treatment of HSP in Tibetan children at high altitude, and to analyze the possible causes of HSP in children at high altitude. The risk factors of the disease provide a reference for the treatment of HSP in children in high altitude areas. <strong>Methods:</strong> Selecting January 2015 to November 2020, 88 children diagnosed with Henoch-Schonlein Purpura in the outpatient and inpatient departments of the People’s Hospital of Bomi County, Tibet Autonomous Region were the subjects of the study. Its gender, age of onset, season of onset, predisposing factors, allergy history, first symptoms, clinical manifestations, laboratory examinations, etc., perform retrospective analysis. <strong>Results: </strong>Among 88 children with allergic purpura, 55 were boys, accounting for 62.5%, and 33 were girls, accounting for 37.5%. Men have more cases than women. All have clinical manifestations of purpura of the skin, among which 35 cases have obvious triggers, of which the above there were 26 cases of respiratory infections, 6 cases of dietary factors, and 3 cases of contact with allergic substances. Simple skin type: 18 cases, accounting for 20.45%;Abdominal type: 6 cases, accounting for 6.82%;2 male cases, accounting for 33.33%;4 female cases, accounting for 66.67%;Articular type: 8 cases, accounting for 33.33%;Renal type: 2 cases, accounting for 2.27%;54 cases of mixed type, accounting for 61.36%. After glucocorticoids, the rashes disappeared, no any adverse reactions. <strong>Conclusion:</strong> Allergic purpura in children is more common in school-age children, and upper respiratory tract infection is the main predisposing factor. Skin purpura is the main clinical manifestation, often associated with lower extremity joint swelling a
文摘Morbidity associated with conjunctivitis is higher in developing countries,particularly among children,because of the poorer standards of living（Azari and Barney,2013;Yetman and Coody,1997）.Presently,little is known regarding the microorganisms that cause conjunctivitis in the remote area of Chinese Tibet.In particular,it is difficult to monitor and control the occurrence of conjunctivitis in children from this area.
