Background: This study aimed to evaluate the diagnostic value of interferon-γ release assay (IGRA), a sensitive microbiological diagnostic method, in children and adolescents with suspected tuberculosis in a country ...Background: This study aimed to evaluate the diagnostic value of interferon-γ release assay (IGRA), a sensitive microbiological diagnostic method, in children and adolescents with suspected tuberculosis in a country with a high burden of tuberculosis. Method: This study included 581 children and adolescents aged 4 - 19 years who were suspected of having tuberculosis, were latently infected with Mycobacterium tuberculosis, and had received at least one dose of BCG vaccine between April 17, 2019, and February 24, 2021. The study evaluated the TST results of 106 patients who had a positive Quantiferon test and were suspected of having tuberculosis. Results: The study included 581 patients aged between 4 and 19 years. Of these, 106 patients tested positive for the Quantiferon test, while 19 were indeterminate and 456 were negative. The Quantiferon test positivity rate was 18.24%. Among the 106 QFT-Plus-positive cases, 23 patients also tested positive for TST. The difference in distribution was found to be statistically significant. Conclusion: The QFT-Plus test is considered an alternative to TST and other microbiological diagnostic methods for early tuberculosis diagnosis, particularly in children and adolescents.展开更多
Background: More than half (54.4 percent) of adults, one in every six children under five years old (16.7 percent), and one in every eight adolescents (12.5 percent) are overweight or obese in Mongolia. Methods: The s...Background: More than half (54.4 percent) of adults, one in every six children under five years old (16.7 percent), and one in every eight adolescents (12.5 percent) are overweight or obese in Mongolia. Methods: The study was conducted during 2015-2018 including 500 children from kindergarten №5, 350 school children aged 6 - 18 years old, 320 civil servants aged 22 - 60, 250 people in private sectors in Yesonbulag, Govi-Altai province, Mongolia. Community based Cross sectional study was undertaken. Questionnaire was used to interview the study participants and anthropometry measurements were performed. Body mass index was calculated by Kettle index (BMI = weight (kg)/height (m<sup>2</sup>)) and SPSS-17 was utilized for statistical analysis of the data. Fasting blood was tested for parameters including glucose, high density lipoprotein, triglycerides, cholesterol in the blood test of 170 people using analyzer (SPOTCHEM<sup>TM</sup> EZ model SP-4430, Japan). Result: 32% of the preschool children were at risk of becoming overweight, 10% were overweight, 8% were obese, 40% of school age children were overweight, 6% of them were obese and the obesity and overweight prevalence among adolescents were statistically significant (р < 0.0001) than the other age group children. 34.8% of the self-employed people were overweight, 56.8% were obese and 67% of men and 87% of women had central obesity. 74.4% don’t do any active physical activity or sports and 70% responded that there is a space barrier for doing sports activity. 38% of the civil servants were overweight and 30.5% were obese. The blood test for self-employed people revealed that 33.3% of them were at high risk of high cholesterol level and triglyceride, high density lipoprotein and glucose parameters were normal. 38.2% of the civil servants were at high risk of high cholesterol level. Conclusion: Preschool children are at risk of becoming overweight because of watching cartoons for long hours, use a lot of sweet cookies and drinks. 40% of school age children w展开更多
文摘Background: This study aimed to evaluate the diagnostic value of interferon-γ release assay (IGRA), a sensitive microbiological diagnostic method, in children and adolescents with suspected tuberculosis in a country with a high burden of tuberculosis. Method: This study included 581 children and adolescents aged 4 - 19 years who were suspected of having tuberculosis, were latently infected with Mycobacterium tuberculosis, and had received at least one dose of BCG vaccine between April 17, 2019, and February 24, 2021. The study evaluated the TST results of 106 patients who had a positive Quantiferon test and were suspected of having tuberculosis. Results: The study included 581 patients aged between 4 and 19 years. Of these, 106 patients tested positive for the Quantiferon test, while 19 were indeterminate and 456 were negative. The Quantiferon test positivity rate was 18.24%. Among the 106 QFT-Plus-positive cases, 23 patients also tested positive for TST. The difference in distribution was found to be statistically significant. Conclusion: The QFT-Plus test is considered an alternative to TST and other microbiological diagnostic methods for early tuberculosis diagnosis, particularly in children and adolescents.
文摘Background: More than half (54.4 percent) of adults, one in every six children under five years old (16.7 percent), and one in every eight adolescents (12.5 percent) are overweight or obese in Mongolia. Methods: The study was conducted during 2015-2018 including 500 children from kindergarten №5, 350 school children aged 6 - 18 years old, 320 civil servants aged 22 - 60, 250 people in private sectors in Yesonbulag, Govi-Altai province, Mongolia. Community based Cross sectional study was undertaken. Questionnaire was used to interview the study participants and anthropometry measurements were performed. Body mass index was calculated by Kettle index (BMI = weight (kg)/height (m<sup>2</sup>)) and SPSS-17 was utilized for statistical analysis of the data. Fasting blood was tested for parameters including glucose, high density lipoprotein, triglycerides, cholesterol in the blood test of 170 people using analyzer (SPOTCHEM<sup>TM</sup> EZ model SP-4430, Japan). Result: 32% of the preschool children were at risk of becoming overweight, 10% were overweight, 8% were obese, 40% of school age children were overweight, 6% of them were obese and the obesity and overweight prevalence among adolescents were statistically significant (р < 0.0001) than the other age group children. 34.8% of the self-employed people were overweight, 56.8% were obese and 67% of men and 87% of women had central obesity. 74.4% don’t do any active physical activity or sports and 70% responded that there is a space barrier for doing sports activity. 38% of the civil servants were overweight and 30.5% were obese. The blood test for self-employed people revealed that 33.3% of them were at high risk of high cholesterol level and triglyceride, high density lipoprotein and glucose parameters were normal. 38.2% of the civil servants were at high risk of high cholesterol level. Conclusion: Preschool children are at risk of becoming overweight because of watching cartoons for long hours, use a lot of sweet cookies and drinks. 40% of school age children w
