目的分析不同分娩方式对足月新生儿脐血皮质醇水平的影响及其与并发新生儿湿肺(tachypnea of newborn,TTN)的关系,进一步揭示选择性剖宫产足月儿TTN的发病机理,为选择性剖宫产足月儿TTN的早期防治提供理论依据。方法根据分娩方式的不同...目的分析不同分娩方式对足月新生儿脐血皮质醇水平的影响及其与并发新生儿湿肺(tachypnea of newborn,TTN)的关系,进一步揭示选择性剖宫产足月儿TTN的发病机理,为选择性剖宫产足月儿TTN的早期防治提供理论依据。方法根据分娩方式的不同将120例新生儿分为选择性剖宫产组60例、非选择性剖宫产组30例、自然分娩组30例,其中选择性剖宫产组分为选择性剖宫产TTN组(并发TTN)30例及选择性剖宫产对照组(未并发TTN)30例。在足月新生儿娩出5 min内留取脐静脉血备检,应用电化学发光法测定其脐血皮质醇含量并进行比较。结果 (1)选择性剖宫产组脐血皮质醇水平低于非选择性剖宫产组及自然分娩组,差异有统计学意义(P<0.01)。(2)选择性剖宫产TTN组脐血皮质醇水平低于选择性剖宫产对照组,差异有统计学意义(P<0.01)。(3)选择性剖宫产组及选择性剖宫产TTN组中男性与女性脐血皮质醇水平差异无统计学意义(P>0.05)。结论选择性剖宫产足月儿脐血皮质醇水平低于非选择性剖宫产儿及自然分娩儿,其机理可能与选择性剖宫产儿的应激状态不完善有关;选择性剖宫产足月儿脐血皮质醇水平降低可能与TTN的发生密切相关。展开更多
<strong>Introduction:</strong> <span style="font-family:Verdana;">Respiratory pathologies are top listed amongst neonatal morbidities.</span><span style="font-family:"&qu...<strong>Introduction:</strong> <span style="font-family:Verdana;">Respiratory pathologies are top listed amongst neonatal morbidities.</span><span style="font-family:""> </span><span style="font-family:""><span style="font-family:Verdana;">Our objective was to describe the clinical features, causes and treatment of respiratory distress (RD) in full and post term neonates in a tertiary health center in Yaoundé, the Essos Hospital Centre (EHC). </span><b><span style="font-family:Verdana;">Patients and Method: </span></b><span style="font-family:Verdana;">This was a retrospective study. Full/post term neonates with RD from January 2017-December 2018 were included.</span></span><span style="font-family:""> </span><span style="font-family:""><span style="font-family:Verdana;">Main parameters: incidence of RD, etiologies, risk factors for severity and mortality. </span><b><span style="font-family:Verdana;">Results: </span></b><span style="font-family:Verdana;">We included 186 neonates among 2312 newborn babies. The RD prevalence rate was 8%. Sex ratio of 2.15 was favoring male, median gestational age of 38 weeks. Clinical signs of RD were dominated by a Silverman score above 4/10 in 64%.</span></span><span style="font-family:""> </span><span style="font-family:Verdana;">Main etiologies were pneumonia (44%),</span><span style="font-family:""> </span><span style="font-family:""><span style="font-family:Verdana;">followed by transient ta</span><span style="font-family:Verdana;">chypnea</span></span><span style="font-family:""> </span><span style="font-family:Verdana;">(35.4).</span><span style="font-family:""> </span><span style="font-family:Verdana;">Perinatal asphyxia</span><span style="font-family:""> </span><span style="font-family:Verdana;">(OR</span><span style="font-family:""> </span><span style="font-family:Verdana;">=</span><span style="font-family:""> </span><span style="font-family:Verdana;">9.412, P</span><span style="font-family:""> </span><span style="font-family:Verdana;">=</span><span style="font-family:"展开更多
文摘目的分析不同分娩方式对足月新生儿脐血皮质醇水平的影响及其与并发新生儿湿肺(tachypnea of newborn,TTN)的关系,进一步揭示选择性剖宫产足月儿TTN的发病机理,为选择性剖宫产足月儿TTN的早期防治提供理论依据。方法根据分娩方式的不同将120例新生儿分为选择性剖宫产组60例、非选择性剖宫产组30例、自然分娩组30例,其中选择性剖宫产组分为选择性剖宫产TTN组(并发TTN)30例及选择性剖宫产对照组(未并发TTN)30例。在足月新生儿娩出5 min内留取脐静脉血备检,应用电化学发光法测定其脐血皮质醇含量并进行比较。结果 (1)选择性剖宫产组脐血皮质醇水平低于非选择性剖宫产组及自然分娩组,差异有统计学意义(P<0.01)。(2)选择性剖宫产TTN组脐血皮质醇水平低于选择性剖宫产对照组,差异有统计学意义(P<0.01)。(3)选择性剖宫产组及选择性剖宫产TTN组中男性与女性脐血皮质醇水平差异无统计学意义(P>0.05)。结论选择性剖宫产足月儿脐血皮质醇水平低于非选择性剖宫产儿及自然分娩儿,其机理可能与选择性剖宫产儿的应激状态不完善有关;选择性剖宫产足月儿脐血皮质醇水平降低可能与TTN的发生密切相关。
文摘<strong>Introduction:</strong> <span style="font-family:Verdana;">Respiratory pathologies are top listed amongst neonatal morbidities.</span><span style="font-family:""> </span><span style="font-family:""><span style="font-family:Verdana;">Our objective was to describe the clinical features, causes and treatment of respiratory distress (RD) in full and post term neonates in a tertiary health center in Yaoundé, the Essos Hospital Centre (EHC). </span><b><span style="font-family:Verdana;">Patients and Method: </span></b><span style="font-family:Verdana;">This was a retrospective study. Full/post term neonates with RD from January 2017-December 2018 were included.</span></span><span style="font-family:""> </span><span style="font-family:""><span style="font-family:Verdana;">Main parameters: incidence of RD, etiologies, risk factors for severity and mortality. </span><b><span style="font-family:Verdana;">Results: </span></b><span style="font-family:Verdana;">We included 186 neonates among 2312 newborn babies. The RD prevalence rate was 8%. Sex ratio of 2.15 was favoring male, median gestational age of 38 weeks. Clinical signs of RD were dominated by a Silverman score above 4/10 in 64%.</span></span><span style="font-family:""> </span><span style="font-family:Verdana;">Main etiologies were pneumonia (44%),</span><span style="font-family:""> </span><span style="font-family:""><span style="font-family:Verdana;">followed by transient ta</span><span style="font-family:Verdana;">chypnea</span></span><span style="font-family:""> </span><span style="font-family:Verdana;">(35.4).</span><span style="font-family:""> </span><span style="font-family:Verdana;">Perinatal asphyxia</span><span style="font-family:""> </span><span style="font-family:Verdana;">(OR</span><span style="font-family:""> </span><span style="font-family:Verdana;">=</span><span style="font-family:""> </span><span style="font-family:Verdana;">9.412, P</span><span style="font-family:""> </span><span style="font-family:Verdana;">=</span><span style="font-family:"
