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紧张性头痛患者生活质量及其与自我效能、应对方式的关系 被引量:18
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作者 满孝典 刘晓芹 孙宏伟 《中国健康心理学杂志》 2015年第5期670-673,共4页
目的:对紧张性头痛患者生活质量及其与自我效能、应对方式的关系进行分析,确定相关关系。方法:采用生活质量综合评定问卷、医学应对问卷和自我效能问卷对被确诊为紧张性头痛的68例患者进行调查,对收集到的数据用SPSS 14.0统计软件进行... 目的:对紧张性头痛患者生活质量及其与自我效能、应对方式的关系进行分析,确定相关关系。方法:采用生活质量综合评定问卷、医学应对问卷和自我效能问卷对被确诊为紧张性头痛的68例患者进行调查,对收集到的数据用SPSS 14.0统计软件进行统计分析。结果:1紧张性头痛患者生活质量和自我效能感得分显著低于常模且较多的选择回避和屈服应对方式(t=-12.909,P<0.001);2紧张性头痛患者生活质量及其各领域与自我效能感呈显著正相关(r=0.783,P<0.01)而与屈服应对方式呈显著负相关(r=-0.810,P<0.01),面对应对方式与心理领域呈显著负相关(r=-0.347,P<0.01)但与社会关系领域呈显著正相关(r=0.353,P<0.01);3紧张性头痛患者的自我效能感对患者生活质量有直接促进作用且通过抑制患者选择屈服应对方式对患者生活质量有间接促进作用。结论:提高紧张性头痛患者自我效能感,减少屈服应付方式的选择能够有效提高紧张性头痛患者的生活质量。 展开更多
关键词 紧张性头痛 生活质量 自我效能感 应对方式
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Regional homogeneity abnormalities in patients with tensiontype headache:a resting-state fMRI study 被引量:7
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作者 Pian Wang Handan Du +4 位作者 Ning Chen Jian Guo Qiyong Gong Junran Zhang Li He 《Neuroscience Bulletin》 SCIE CAS CSCD 2014年第6期949-955,共7页
Tension-type headache(TTH) is the most prevalent type of primary headache. Many studies have shown that the pathogenesis of primary headache is associated with fine structural or functional changes. However, these s... Tension-type headache(TTH) is the most prevalent type of primary headache. Many studies have shown that the pathogenesis of primary headache is associated with fine structural or functional changes. However, these studies were mainly based on migraine. The present study aimed to investigate whether TTH patients show functional disturbances compared with healthy subjects. We used restingstate functional magnetic resonance imaging(f MRI) and regional homogeneity(Re Ho) analysis to identify changes in the local synchronization of spontaneous activity in patients with TTH. Ten patients with TTH and 10 age-, gender-, and education-matched healthy controls participated in the study. After demographic and clinical characteristics were acquired, a 3.0-T MRI system was used to obtain restingstate f MRIs. Compared with healthy controls, the TTH group exhibited significantly lower Re Ho values in the bilateral caudate nucleus, the precuneus, the putamen, the left middle frontal gyrus, and the superior frontal gyrus. There was no correlation between mean Re Ho values in TTH patients and duration of TTH, number of attacks, duration of daily attacks, Visual Analogue Scale score, or Headache Impact Test-6 score. These results suggest that TTHpatients exhibit reduced synchronization of neuronal activity in multiple regions involved in the integration and processing of pain signals. 展开更多
关键词 tension-type headache resting-state fMRI ReHo basal ganglia
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Abnormalities of masseter inhibitory reflex in patients with episodic tension-type headache 被引量:5
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作者 Plamen TZVETANOV Rossen Todoroff ROUSSEFF Zdravka RADIONOVA 《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》 SCIE CAS CSCD 2009年第1期52-56,共5页
Objective: To investigate the masseter inhibitory tension-type headache (TTH). Methods: MIR was studied in 21 sex matched to the study cohort. Median age of patients was reflex (MIR) and its eventual changes in ... Objective: To investigate the masseter inhibitory tension-type headache (TTH). Methods: MIR was studied in 21 sex matched to the study cohort. Median age of patients was reflex (MIR) and its eventual changes in patients with episodic patients with episodic TTH and 30 healthy subjects, with age and 17.0 years (ranged 16-49 years), median duration of disease 12 months (1-5 years), and median frequency of headache 7.5 d per month. Results: The second period of suppression ($2) of MIR was reduced in intensity and duration in 10% of controls and 66.7% (confidence interval (CI) 45.3%-85%; P〈0.05) of patients with episodic TTH (X2=74.9; P〈0.001). In 3 (14.3%) of patients with episodic TTH, S2 was completely absent. No significant correlation between the duration of disease and headache frequency was found. Conclusion: Our results confirm the link between episodic TTH and reduction or absence of S2. Teenage patients with episodic TTH may exhibit marked pathological changes in S2 in contrast to older individuals. 展开更多
关键词 tension-type headache (TTH) Temporalis muscle exteroceptive suppression Masseter inhibitory reflex (MIR)
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Disease-Related Factors Associated with Acupuncture Response in Patients with Chronic Tension-Type Headache:A Secondary Analysis of A Randomized Controlled Trial
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作者 CAO Wei WANG Lu +10 位作者 HOU Ting-hui SHI Yun-zhou ZHENG Qian-hua ZHENG Hui ZOU Zi-hao QIN Di YANG Qian CHEN Si-jue WANG Hai-yan XIAO Xian-jun LI Ying 《Chinese Journal of Integrative Medicine》 SCIE CAS CSCD 2024年第8期684-691,共8页
Objective To explore the demographic and disease-related factors associated with acupuncture response in patients with chronic tension-type headache(CTTH).Methods Using data from a randomized clinical trial(218 cases)... Objective To explore the demographic and disease-related factors associated with acupuncture response in patients with chronic tension-type headache(CTTH).Methods Using data from a randomized clinical trial(218 cases)consisting of 4 weeks of baseline assessment,8 weeks of treatment,and 24 weeks of follow-up,participants were regrouped into responders(at least a 50%reduction in monthly headache days at week 16 compared with baseline)and non-responders.Twenty-three demographic and disease-related factors associated with acupuncture response in 183 participants were analyzed by multivariable logistic regression.Results One hundred and nineteen(65.0%)participants were classified as responders.Four factors were significantly independently associated with acupuncture response,including treatment assignment,headache intensity at baseline,and 2 domains[general health(GH)and social functioning(SF)]from the 36-Item Short Form Health Survey quality of life questionnaire.Treatment assignment was associated with non-response:participants receiving true acupuncture were 3-time more likely to achieve a CTTH response than those receiving superficial acupuncture[odds ratio(OR)0.322,95%confidence interval(CI)0.162 to 0.625,P=0.001].Compared with patients with mild-intensity headache,patients with moderate-intensity headache were twice as likely to respond to acupuncture(OR 2.001,95%CI 1.020 to 4.011,P=0.046).The likelihood of non-response increased by 4.5%with each unit increase in the GH grade(OR 0.955,95%CI 0.917 to 0.993,P=0.024)while decreased by 3.8%with each unit increase in the SF grade(OR 1.038,95%CI 1.009 to 1.069,P=0.011).Conclusions Greater headache intensity,lower GH score,and higher SF score were associated with better acupuncture responses in CTTH patients.These 3 factors require independent validation as predictors of acupuncture effectiveness in CTTH. 展开更多
关键词 ACUPUNCTURE chronic tension-type headache logistic regression quality of life Chinese medicine
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Effectiveness and safety of Xuefu Zhuyu oral liquid(血府逐瘀口服液)on Qi-stagnation and blood-stasis pattern in patients with stable angina,tension-type headache and primary dysmenorrhea:rationale and design of a master protocol
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作者 CAO Wencong LIAO Shaojun +4 位作者 ZHANG Yuanwen ZHOU Li LI Geng OUYANG Wenwei WEN Zehuai 《Journal of Traditional Chinese Medicine》 SCIE CSCD 2023年第4期815-823,共9页
We present the rationale and design of a master protocol study that clarifies the effectiveness and safety of Chinese herbal formulas on Qi-stagnation and blood-stasis pattern(QBP).Three randomized controlled trials(R... We present the rationale and design of a master protocol study that clarifies the effectiveness and safety of Chinese herbal formulas on Qi-stagnation and blood-stasis pattern(QBP).Three randomized controlled trials(RCTs)and real-world observational studies.Based on three registry cohorts of stable angina,tension-type headache and primary dysmenorrhea,patients with QBP will be enrolled in RCTs to receive either Xuefu Zhuyu(血府逐瘀,XFZY)oral liquid or a placebo,while patients with non-QBP will be enrolled in the observational studies and experience follow-up.1414 patients(RCTs:574;observational studies:840)will be recruited at seven centers in China over a 3-year period.The primary outcome is the visual analog scale of pain intensity.Adverse events will also be reported.The analysis will be undertaken separately in each sub-study,and then an overall analysis combining multiple subgroups will be performed to comprehensively investigate the effect of XFZY oral liquid.This study will provide high-quality evidence of XFZY oral liquid for QBP patients and show a paradigm of post-marketing evaluation of the effectiveness and safety for Chinese medicine following the notion of the pattern dominating different disease research models. 展开更多
关键词 ANGINA stable tension-type headache primary dysmenorrhea Chinese herbal formula Chinese medicine pattern master protocol
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Clinical Efficacy and Safety of Miniscalpel-Needle Treatment for Tension-Type Headache:A Systematic Review and Meta-Analysis 被引量:3
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作者 Chan-Young Kwon Sang-Hoon Yoon +1 位作者 Sun-Yong Chung Jong Woo Kim 《Chinese Journal of Integrative Medicine》 SCIE CAS CSCD 2020年第9期713-720,共8页
Objective:To investigate the clinical efficacy and safety of miniscalpel-needle(MSN)treatment for tension-type headache(TTH).Method:Seven medical databases were searched to identify randomized controlled trials(RCTs)e... Objective:To investigate the clinical efficacy and safety of miniscalpel-needle(MSN)treatment for tension-type headache(TTH).Method:Seven medical databases were searched to identify randomized controlled trials(RCTs)evaluating the effect and safety of MSN treatment.All articles published up to November 15,2018 were retrieved.A meta-analysis was conducted for the included studies,and the risk of bias was assessed.Primary outcomes were visual analogue scale(VAS)or numeric rating scale(NRS)score.Secondary outcomes were clinical effective rates including total effective rate(TER),markedly effective rate(MER),and totally cured rate(TCR)determined by improvement in clinical symptoms or VAS scores,the frequency of adverse events(AEs)that occurred during the study,and participant quality of life(QOL).Results:Seven RCTs involving 724 participants were included.MSN treatment showed significantly higher MER and TCR[relative risk(RR)1.27,95%confidence interval(Cl)1.01 to 1.61;RR 1.31,95%Cl 1.09 to 1.57,respectively],but not TER(RR 1.03,95%Cl 0.96 to 1.10)compared to acupuncture.MSN treatment plus conventional treatment showed significant lower VAS and higher TER,MER,and TCR(mean difference-3.54,95%Cl-3.80 to-3.28;RR 1.14,95%Cl 1.06 to 1.23;RR 2.31,95%Cl 1.50 to 3.58;RR 3.01,95%Cl 2.25 to 4.02,respectively)compared to conventional treatment.Conclusions:According to current evidence,MSN treatment as a monotherapy or as an adjunctive treatment to other existing treatments might have benefits on treating TTH.However,since the number and the sample size of studies included were both small and the methodological quality was poor,the findings of this review should be interpreted with great caution,and our confidence in the results is low.A high quality RCT using objective outcomes should be performed on this topic. 展开更多
关键词 ACUPUNCTURE ACUPOTOMY tension-type headache systematic review META-ANALYSIS
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Review on the Anchoring Mechanism and Application Research of Compression-Type Anchor
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作者 Jiansheng Tian Li Hu 《Engineering(科研)》 2016年第11期777-788,共12页
To apply the compression-type anchor to deep roadways, this paper analyzes and summaries the bearing mechanism, shear stress distribution of the grout body and engineering application of the compression-type anchor. T... To apply the compression-type anchor to deep roadways, this paper analyzes and summaries the bearing mechanism, shear stress distribution of the grout body and engineering application of the compression-type anchor. The analysis shows that the compression-type anchor has the advantages of reasonable grout body stress form, high loading capacity, good corrosion resistance and durability. The analysis also indicates that further study on the stress distribution of the compression-type anchor’s grout body and the design of a new compression-type anchor with high strength initial support, simple structure, and small diameter that is suitable for the surrounding rock in deep roadway engineering is necessary to apply compression-type anchor supporting technology to the deep roadway. 展开更多
关键词 tension-type Anchor Compression-type Anchor Grout Body Fixed End
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Registration of intervention trials of Traditional Chinese Medicine for four neurological diseases on Chinese Clinical Trial Registry and Clinical Trials.gov:a narrative review 被引量:1
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作者 WEI Jingjing GUO Rongjuan +12 位作者 FU Guojing LIANG Xiao XU Zhenmin JIA Min ZENG Zixiu DU Wanqing JIAO Weiwei SUN Linjuan LIU Hongmei GUO Chunli TONG Chenguang ZHANG Yunling LIAO Xing 《Journal of Traditional Chinese Medicine》 SCIE CSCD 2022年第1期148-153,共6页
OBJECTIVE:To analyze the current status of clinical trial registration of Traditional Chinese Medicine(TCM)for the treatment of neurological diseases.METHODS:Interventional clinical trials of TCM treatment for ischemi... OBJECTIVE:To analyze the current status of clinical trial registration of Traditional Chinese Medicine(TCM)for the treatment of neurological diseases.METHODS:Interventional clinical trials of TCM treatment for ischemic stroke,hemorrhagic stroke,vascular cognitive impairment,tension-type headache before September 22,2020 on the platform of Chinese Clinical Trial Registry(Chi CTR),and Clinical Trials.gov were searched.Two researchers independently selected the literature and extracted data.RESULTS:A total of 180 interventional clinical trials were included for analysis.Out of 180 trials,127 were from Chi CTR and 53 from Clinical Trials.gov.The countries primary sponsoring the included trials were China(176,97.8%),and the common categories of primary sponsors were hospital(131,72.8%).Among the study design,the largest proportion of allocation was randomized(172,95.6%),interventional model assignment was parallel(163,90.6%),masking was double blind 49(27.2%),and the sample size was≤400(144,80.0%).The trials were most carried out at a single center(102,56.7%).Among the included studies,112(62.2%)registered on Chi CTR attached the ethical approval documents.In terms of trial stages,50(27.7%)studies were in phaseⅣ.The mostly used intervention was Chinese herbal medicines(99,55%),acupuncture(68,37.8%)was the second.By searching the registration number on China National Knowledge Infrastructure Database and Pub Med,38(21.1%)registered trials were published,including 25 protocol studies and 14 research results with one(NCT02275949)published both the protocol and the results.CONCLUSIONS:Irregular and inadequate reporting,untimely update and publication,insufficient information on traditional medicine unique characteristics,and lack of international collaborations are the problems existing in the interventional clinical registration trials of traditional medicine treatment on neurological diseases.More efforts need to be made from the above aspects to standardize and improve the registration of traditional medicine trial 展开更多
关键词 medicine Chinese traditional ischemic stroke cognitive dysfunction tension-type headache hemorrhagic stroke Chinese Clinical Trial Registry Clinical Trials.gov critical appraisal
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Clinical study on acupuncture plus auricular point sticking for tension-type headache 被引量:2
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作者 Fei Ke Wang Feng 《Journal of Acupuncture and Tuina Science》 CSCD 2021年第1期49-55,共7页
Objective:To observe the clinical efficacy of acupuncture plus auricular point sticking for tension-type headache(TTH).Methods:A total of 90 TTH patients were divided into an acupuncture group,an auricular point stick... Objective:To observe the clinical efficacy of acupuncture plus auricular point sticking for tension-type headache(TTH).Methods:A total of 90 TTH patients were divided into an acupuncture group,an auricular point sticking group and an observation group by random number table method,with 30 cases in each group.Patients in the observation group received acupuncture plus auricular point sticking for treatment,while those in the acupuncture group only received acupuncture and those in the auricular point sticking group only received auricular point sticking for treatment.The headache attack frequency and the scores of visual analog scale(VAS),self-rating anxiety scale(SAS)and self-rating depression scale(SDS)were observed before treatment,after treatment and 3 months after treatment.The clinical efficacy was evaluated at the follow-up of 3 months after treatment.Results:At follow-up,there were significant differences in clinical efficacy among the three groups(P<0.01 or P<0.05),and the clinical efficacy ranking from high to low was the observation group,the acupuncture group and the auricular point sticking group.After treatment and at follow-up,the VAS score,headache attack frequency,SAS and SDS scores in the three groups were significantly lower than those before treatment(all P<0.01).The above four results in the observation group were lower than those in the acupuncture group and the auricular point sticking group at the same time point(all P<0.01);VAS score in the acupuncture group was lower than that in the auricular point sticking group(both P<0.05).At follow-up,the headache frequency in the acupuncture group was lower than that in the auricular point sticking group(P<0.05).Conclusion:Either using acupuncture and auricular point sticking together or separately can reduce the headache degree of TTH patients,reduce the number of headache attacks,and relieve anxiety and depression.The efficacy of acupuncture plus auricular point sticking is most significant. 展开更多
关键词 Acupuncture Therapy Auricular Point Sticking Visual Analog Scale Pain Measurement ANXIETY DEPRESSION tension-type Headache
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紧张型头痛患者的生活事件、心身症状及其相关关系 被引量:2
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作者 黄秀琴 张倩 +3 位作者 杨小柳 何晓冰 骆利 苑宏 《中国健康心理学杂志》 2005年第3期168-169,共2页
目的探讨紧张型头痛(TTH)住院患者的生活事件、心身症状及其相关关系。方法将35例诊断为TTH的住院军人作为患者组,以35名正常军人作为对照组,分别用生活事件量表及症状自评量表(SCL—90)对他们的生活事件及心身症状进行评定,并对二者进... 目的探讨紧张型头痛(TTH)住院患者的生活事件、心身症状及其相关关系。方法将35例诊断为TTH的住院军人作为患者组,以35名正常军人作为对照组,分别用生活事件量表及症状自评量表(SCL—90)对他们的生活事件及心身症状进行评定,并对二者进行相关分析。结果TTH患者所经历的正性生活事件分值低于对照组(P<0.01)、而负性生活事件分值高于对照组(P<0.01),两组间生活事件总值无差异(P>0.05)。TTH患者SCL—90的躯体化、人际敏感、抑郁、焦虑、恐怖、偏执及精神病性因子分均高于对照组(P<0.05),强迫、敌对因子分与对照组无差别(P>0.05)。SCL-90总分及阳性项目数与正性生活事件之间呈负相关关系(P<0.01),与负性生活事件之间呈正相关关系(P<0.01),与生活事件总值之间无明显相关关系(P>0.05)。结论TTH住院军人经历了较多的不良生活事件,也出现较多的心身症状。 展开更多
关键词 相关关系 心身症状 紧张型头痛 症状自评量表(SCL-90) 负性生活事件 生活事件量表 不良生活事件 住院军人 对照组 阳性项目数 TTH 住院患者 相关分析 人际敏感 精神病性 因子分 躯体化 分值 正性
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Efficacy and Effect of SI17 Therapy on Pancreatic Polypeptide in Vascular and Tension-Type Headache
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作者 张小澍 李永昌 +4 位作者 任淑梅 匡培根 吴卫平 张凤英 刘洁晓 《Journal of Traditional Chinese Medicine》 SCIE CAS CSCD 2000年第3期206-209,共4页
  Background and purpose: Vascular and tension-type headache is most commonly encountered, and SI17 therapy has been tested to treat headache with good results. The efficacy of SI17 therapy for vascular and tension-...   Background and purpose: Vascular and tension-type headache is most commonly encountered, and SI17 therapy has been tested to treat headache with good results. The efficacy of SI17 therapy for vascular and tension-type headache was compared and the effect of SI17 therapy on pancreatic polypeptide (PP) was studied. Materials and methods: 29 cases of vascular headache (20 cases in acute attack during the trial) and 27 cases of tension-type headache (19 cases in acute attack) were enrolled in the study. Plasma PP level before and 4th day after treatment was measured by radioimmunoassay. Results: SI17 therapy is better for the treatment of vascular headache. Vascular headache with higher PP level and tension-type headache with normal PP level had good therapeutic results. Conclusion: The clinical efficacy is better for vascular headache with the increase of vagus tension and for tension-type headache with normal vagus tension.   展开更多
关键词 Acupuncture Points ADOLESCENT ADULT Aged CHILD DEXAMETHASONE Female Humans INJECTIONS Male Middle Aged Pancreatic Polypeptide tension-type Headache Vascular Headaches
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101例偏头痛和95例紧张型头痛患者伴发焦虑和/或抑郁临床分析 被引量:41
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作者 郭那那 吴川杰 +2 位作者 连亚军 顾盼 陈洁 《中国疼痛医学杂志》 CAS CSCD 北大核心 2012年第9期529-532,共4页
目的:分析就诊于神经内科门诊的偏头痛和紧张型头痛患者中焦虑抑郁的发生率及特点,旨在提高偏头痛和紧张型头痛患者的诊疗水平。方法:对2009年6月~2010年2月来我院神经内科就诊101例偏头痛和95例紧张型头痛患者,采用汉密顿焦虑和抑郁... 目的:分析就诊于神经内科门诊的偏头痛和紧张型头痛患者中焦虑抑郁的发生率及特点,旨在提高偏头痛和紧张型头痛患者的诊疗水平。方法:对2009年6月~2010年2月来我院神经内科就诊101例偏头痛和95例紧张型头痛患者,采用汉密顿焦虑和抑郁量表进行焦虑抑郁测定,并同时对性别、年龄、职业、收入状况、病程、头痛程度、发作频率进行分析。结果:44.6%偏头痛患者和55.8%紧张型头痛患者伴发情绪障碍,两者比较无统计学差异(P〉0.05)。慢性紧张性头痛患者有情绪障碍的概率较发作性紧张性头痛患者、无先兆偏头痛患者、有先兆偏头痛患者无统计学差异(P〉0.05)。有焦虑症状的头痛患者出现抑郁症状显著高于无焦虑症状的患者,反之亦然。女性头痛患者伴发焦虑抑郁显著高于男性(P〈0.05)。年龄〈40岁患者伴发焦虑抑郁明显高于年龄〉40岁患者(P〈0.05)。收入〈1500(元/月)的头痛患者伴发焦虑抑郁显著高于收入≥1500(元/月)。中、重度头痛患者伴发焦虑抑郁显著高于轻度头痛(P〈0.05)。头痛病程〉1年患者伴发焦虑抑郁显著高于病程〈1年(P〈0.05)。结论:偏头痛和紧张型头痛患者经常伴有焦虑抑郁。在头痛患者的诊治中,应加强对偏头痛及紧张型头痛共患焦虑抑郁的认识,提高诊治水平。 展开更多
关键词 偏头痛 紧张型头痛 焦虑 抑郁
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氟哌噻吨美利曲辛联合右佐匹克隆治疗伴抑郁和(或)焦虑状态及失眠症状的慢性紧张型头痛的临床疗效研究 被引量:34
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作者 李英杰 李亚楠 +3 位作者 郭英俊 徐谦 王冰洁 孔桂良 《中国全科医学》 CAS CSCD 北大核心 2013年第8期864-866,共3页
目的探讨氟哌噻吨美利曲辛联合右佐匹克隆治疗伴有抑郁和(或)焦虑状态及失眠症状的慢性紧张型头痛(CTH)的有效性及安全性。方法选取2011年2—11月于我院神经内科门诊就诊的100例伴有抑郁和(或)焦虑状态及失眠症状的CTH患者,随机分为氟... 目的探讨氟哌噻吨美利曲辛联合右佐匹克隆治疗伴有抑郁和(或)焦虑状态及失眠症状的慢性紧张型头痛(CTH)的有效性及安全性。方法选取2011年2—11月于我院神经内科门诊就诊的100例伴有抑郁和(或)焦虑状态及失眠症状的CTH患者,随机分为氟哌噻吨美利曲辛联合右佐匹克隆治疗组(联合组)及氟哌噻吨美利曲辛单药治疗组(单药组)各50例,疗程8周。用疼痛视觉模拟评分(VAS)卡尺、汉密尔顿抑郁量表(HAMD)、汉密尔顿焦虑量表(HAMA)、匹茨堡睡眠质量指数量表(PSQI)评定疗效,采用不良反应症状量表(TESS)及8周末实验室检查结果评定治疗的安全性。结果单药组及联合组患者VAS、HAMD、HAMA、PSQI评分同组内治疗前后比较,差异均有统计学意义(P<0.05)。其中单药组治疗2周末VAS、HAMD、HAMA评分与治疗前比较,差异均有统计学意义(P<0.05),治疗8周末VAS、HAMD、HAMA、PSQI评分与治疗前比较,差异均有统计学意义(P<0.05);联合组治疗2周末及8周末VAS、HAMD、HAMA、PSQI评分与治疗前比较,差异均有统计学意义(P<0.05);两组治疗8周末VAS、HAMD、HAMA、PSQI评分分别与2周末比较,差异均有统计学意义(P<0.05)。联合组治疗前VAS、HAMD、HAMA、PSQI评分与单药组比较,差异均无统计学意义(P>0.05);联合组在治疗2周末HAMA、PSQI评分与单药组比较,差异均有统计学意义(P<0.05);治疗8周末PSQI评分与单药组比较,差异有统计学意义(P<0.05)。两组治疗后2周TESS评分〔(3.23±1.36)分vs.(3.11±1.42)分〕及8周TESS评分〔(3.96±1.31)分vs.(3.94±1.44)分〕比较,差异均无统计学意义(t=0.43,P=0.68;t=0.07,P=0.94)。两组患者血尿常规、肝肾功能、血压及心电图治疗前后均无异常变化。结论氟哌噻吨美利曲辛联合右佐匹克隆治疗抑郁和(或)焦虑状态及失眠症状的CTH疗效更好,在改善睡眠质量和焦虑情绪方面起效快,耐受性好,无明显不良反应。 展开更多
关键词 紧张性头痛 抑郁 焦虑 入睡和睡眠障碍 氟哌噻吨美利曲辛 右佐匹克隆
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针刺阿是穴及安神六穴治疗紧张型头痛伴情绪障碍的疗效观察 被引量:21
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作者 姚旭 谭克平 《中华中医药杂志》 CAS CSCD 北大核心 2019年第1期398-400,共3页
目的:观察阿是穴配合安神六穴[心(耳穴)、肺(耳穴)、神门(耳穴)、迎香、神门、足三里]针刺治疗紧张型头痛伴情绪障碍(焦虑、抑郁)患者的临床疗效。方法:采用随机对照试验设计,将65例患者随机分为治疗组和对照组,治疗组33例,对照组32例;... 目的:观察阿是穴配合安神六穴[心(耳穴)、肺(耳穴)、神门(耳穴)、迎香、神门、足三里]针刺治疗紧张型头痛伴情绪障碍(焦虑、抑郁)患者的临床疗效。方法:采用随机对照试验设计,将65例患者随机分为治疗组和对照组,治疗组33例,对照组32例;治疗组采用头项部阿是穴配合安神六穴针刺治疗;对照组采用常规穴位针刺治疗;两组均隔日治疗1次,每周3次,共6周,观察患者治疗前后头痛、抑郁和焦虑症状程度,并于治疗后3个月随访,评定两组临床疗效。结果:两组治疗后头痛评分、抑郁评分和焦虑评分均较本组治疗前明显降低(P<0.05),且治疗组比对照组降低更明显(P<0.05);治疗结束时治疗组总有效率为93.94%,对照组为84.38%,治疗组疗效更佳(P<0.05);3个月后随访,两组总有效率分别为87.88%,75.00%。结论:阿是穴配合安神六穴针刺治疗可显著降低紧张型头痛伴情绪障碍患者的头痛程度,改善抑郁、焦虑症状,近远期疗效优于常规穴位针刺治疗。 展开更多
关键词 紧张型头痛 抑郁 焦虑 阿是穴 耳穴 神门穴
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头痛专病门诊患者抑郁焦虑患病特点分析 被引量:21
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作者 王璐 谢敬耽 +2 位作者 邸海 董钊 于生元 《中国疼痛医学杂志》 CAS CSCD 2015年第8期587-590,共4页
目的:评估头痛门诊原发性头痛患者的抑郁焦虑共病情况。方法:使用9条目患者健康问卷(patient health questionnaire-9,PHQ-9)和7条目广泛性焦虑量表(generalized anxiety disorder-7,GAD-7)对2012年10月8日至2012年12月29日就诊于解放... 目的:评估头痛门诊原发性头痛患者的抑郁焦虑共病情况。方法:使用9条目患者健康问卷(patient health questionnaire-9,PHQ-9)和7条目广泛性焦虑量表(generalized anxiety disorder-7,GAD-7)对2012年10月8日至2012年12月29日就诊于解放军总医院头痛门诊的原发性头痛患者进行评估。结果:在225例头痛患者中,偏头痛为58例(25.8%),紧张型头痛为97例(43.1%),丛集性头痛为14例(6.2%),慢性每日头痛为56例(24.9%);头痛患者的抑郁和广泛性焦虑的检出率分别为37.8%和34.2%。慢性每日头痛出现抑郁和广泛性焦虑共病的比例明显高于其他类型头痛(P<0.01,P=0.03)。结论:头痛专病门诊中原发性头痛的抑郁和广泛性焦虑患病比例高,和其他类型头痛相比,慢性每日头痛更容易出现抑郁焦虑共病。 展开更多
关键词 头痛 偏头痛 紧张型头痛 慢性每日头痛 抑郁 焦虑
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基于R语言数据挖掘的中药治疗紧张型头痛的用药规律探析 被引量:21
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作者 樊雪鸣 王柳丁 +1 位作者 申伟 张允岭 《中草药》 CAS CSCD 北大核心 2021年第15期4614-4625,共12页
目的基于R语言数据挖掘平台对现代文献中紧张型头痛(tension-type headache,TTH)的方药信息进行数据挖掘,为TTH的中药治疗提供新思路。方法计算机检索中国知网、万方、维普、中国生物医学、PubMed、Embase和Cochrane Library共7个国内... 目的基于R语言数据挖掘平台对现代文献中紧张型头痛(tension-type headache,TTH)的方药信息进行数据挖掘,为TTH的中药治疗提供新思路。方法计算机检索中国知网、万方、维普、中国生物医学、PubMed、Embase和Cochrane Library共7个国内外数据库,筛选中药治疗TTH的相关文献。采用Excel软件对方药信息进行提取,采用R语言对中药使用频次、相关性、关联度和聚类等方面进行挖掘分析。结果共提取出中药治疗TTH的306首经验方药,中药共238味,频次共3187次,其中使用频次>100次的药物依次为川芎、白芍、柴胡、甘草、当归和白芷,使用频次>30次的药物以解表药、活血化瘀药、清热药、补虚药、平肝熄风药为主,相关系数较高的前20味药对组合多为补虚药和活血化瘀药,关联分析和聚类分析形成以川芎、白芍、柴胡和当归为基础的核心药物组方。结论中药治疗TTH以川芎、白芍、柴胡和当归为核心药物组方,在此基础上加入针对风、火、痰、虚、瘀等致病因素的相应中药,临床可取得较好疗效。建议后续研究应更多关注TTH的核心药物组方,开展高质量的随机对照试验,为TTH的临床治疗提供新思路。 展开更多
关键词 紧张型头痛 数据挖掘 R语言 中药 用药规律 川芎 白芍 柴胡 当归
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针刺帽状腱膜筋结点治疗慢性紧张型头痛疗效观察 被引量:19
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作者 陈日含 陈日立 陈日锋 《中国针灸》 CAS CSCD 北大核心 2013年第3期219-222,共4页
目的:探寻治疗慢性紧张型头痛的较佳疗法。方法:将288例患者随机分为滞针术组(150例)和针刺组(138例)。滞针术组采用人工滞针术针刺头部帽状腱膜筋结点,针刺组采用常规针刺方法,穴取百会、四神聪、风池、太阳、头维、合谷等,均每天1次,3... 目的:探寻治疗慢性紧张型头痛的较佳疗法。方法:将288例患者随机分为滞针术组(150例)和针刺组(138例)。滞针术组采用人工滞针术针刺头部帽状腱膜筋结点,针刺组采用常规针刺方法,穴取百会、四神聪、风池、太阳、头维、合谷等,均每天1次,30天为一疗程,治疗2个疗程并随访3个月,观察和比较两组治疗前后慢性紧张型头痛(CTTH)评分(包括头痛发作次数评分与头痛程度评分),并评定两组疗效。结果:治疗后两组CTTH评分均降低(均P<0.01),且滞针术组评分低于针刺组(2.38±1.22vs 4.16±2.54,P<0.01);滞针术组有效率为97.3%(146/150),优于针刺组的88.4%(122/138,P<0.05)。结论:人工滞针术针刺帽状腱膜筋结点治疗慢性紧张型头痛可减少疼痛的发作次数,减轻疼痛程度,其疗效优于常规取穴针刺方法。 展开更多
关键词 慢性紧张型头痛 滞针术 帽状腱膜 筋结点 针刺疗法
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310例紧张型头痛患者临床特点分析 被引量:18
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作者 朱玉飞 王璐 +7 位作者 董钊 梁景耀 代维 张明洁 潘美妍 周志彬 李征 于生元 《中国疼痛医学杂志》 CAS CSCD 北大核心 2014年第8期565-568,共4页
目的:探讨紧张型头痛患者的临床特点.方法:回顾性分析解放军总医院国际头痛中心2011年10月到2012年1月就诊的紧张型头痛患者的临床资料.调查内容包括头痛患者的人口学特点、临床特点、伴随症状、触发因素、合并症等.结果:310例紧张... 目的:探讨紧张型头痛患者的临床特点.方法:回顾性分析解放军总医院国际头痛中心2011年10月到2012年1月就诊的紧张型头痛患者的临床资料.调查内容包括头痛患者的人口学特点、临床特点、伴随症状、触发因素、合并症等.结果:310例紧张型头痛患者中,频发性紧张型头痛139例,偶发性紧张型头痛73例,慢性紧张型头痛86例,可能的紧张型头痛12例,男女比例为1:1.38;平均年龄为41.7±13.8岁.患者来源于城市多于农村,高学历者多于低学历者.疼痛部位为单侧105例(33.87%)、双侧157例(50.65%)、全头34例(10.97%)、部位不定14例(4.51%);好发部位依次为枕部(50.65%),其次为颞部(48.39%),顶部(35.48%),额部(31.61%);疼痛性质为胀痛145例(46.77%)、钝痛79例(25.48%)、紧箍感39例(12.59%)、搏动感47例(15.16%);无伴随症状195例,有伴随症状115例,包括恶心、畏声、畏光等;疼痛程度大多为中度(VAS 4~6分)176人(56.77%);诱发因素依次睡眠缺乏115例(37.10%),劳累89例(28.71%),紧张或情绪变化66例(21.29%),天气变化21例(6.77%),饮酒8例(2.58%).慢性紧张型头痛有33例(38.4%)合并药物过量性头痛.结论:紧张型头痛临床表现多种多样,应提高对该疾病的认识,以期早期正确诊断和合理治疗. 展开更多
关键词 紧张型头痛 临床特点 诊断
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紧张型头痛患者椎-基底动脉经颅多普勒超声检查的临床意义 被引量:13
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作者 王振金 李英杰 陈恒年 《中国疼痛医学杂志》 CAS CSCD 2003年第2期67-69,共3页
目的:观察紧张型头痛(TTH)患者椎-基底动脉血流动力学改变,并探讨其临床意义。方法:TTH患者106例,其中伴有颅周肌障碍TTH(TTH-PM)42例和不伴有颅周肌障碍TTH(TTH-NOPM)64例;对照组48例,为无头痛症状的健康体检者。采用经颅多普勒(TCD)... 目的:观察紧张型头痛(TTH)患者椎-基底动脉血流动力学改变,并探讨其临床意义。方法:TTH患者106例,其中伴有颅周肌障碍TTH(TTH-PM)42例和不伴有颅周肌障碍TTH(TTH-NOPM)64例;对照组48例,为无头痛症状的健康体检者。采用经颅多普勒(TCD)脑血流分析技术测定两侧椎动脉(VA)及基底动脉(BA)平均血流速度(Vm)。结果:TTH患者,尤其是TTH-PM患者椎-基底动脉Vm显著增快,且以右侧椎动脉更为明显。结论:TTH患者有椎-基底动脉血流动力学异常,以TTH-PM者更显著。 展开更多
关键词 紧张型头痛 椎-基底动脉 脑血流动力学
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排针平刺法治疗头痛 被引量:17
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作者 林祺 周文珠 +7 位作者 王悦 杨春滟 罗妮莎 范香瀛 寇任重 王琳 侯腾 范刚启 《中国针灸》 CAS CSCD 北大核心 2020年第11期1193-1197,共5页
介绍排针平刺法治疗头痛的手法及操作要点。排针平刺法治疗头痛以局部取穴为主,包括枕穴组、颞穴组、额穴组、顶穴组;针法为排针浅刺、平刺,针刺朝向病灶或头痛部位;留针时间长(6h)。临床常用于治疗偏头痛、颈源性头痛、紧张型头痛,操... 介绍排针平刺法治疗头痛的手法及操作要点。排针平刺法治疗头痛以局部取穴为主,包括枕穴组、颞穴组、额穴组、顶穴组;针法为排针浅刺、平刺,针刺朝向病灶或头痛部位;留针时间长(6h)。临床常用于治疗偏头痛、颈源性头痛、紧张型头痛,操作规范,具有较强的可重复性。 展开更多
关键词 头痛 针刺 排针平刺 偏头痛 颈源性头痛 紧张型头痛
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