M92Si reinforced Mg-Al based composite with high amount o/silicon was prepared by permanent mould casting, and then extruded by reciprocating extrusion （RE） after the composite was processed by homogenization heat t...M92Si reinforced Mg-Al based composite with high amount o/silicon was prepared by permanent mould casting, and then extruded by reciprocating extrusion （RE） after the composite was processed by homogenization heat treatment. The effect of RE processing on the morphology and size of M92Si and the mechanical properties of the com- posite were investigated, to develop new ways to refine the M928i phase and improve its shape. The result showed that RE was very useful in refining the M92Si phase. The more the RE processing passes, the better the refining effect would be. Moreover, the uniform distribution of M928i phases would be more in the composite. After the composite was processed by RE for 12 passes, most M92Si phases were equiaxed, with granular diameter below 20 μm, and distributed uniformly in the matrix of the composite. The mechanical properties of the composite could be increased prominently by RE processing, and were much higher than that in the as-cast state. As the temperature rises, the tensile strength is reduced. For the composite RE processed for 12 passes, the tensile strength, yield strength, and elongation are 325.9 MPa, 211.4 MPa, and 3.3% at room temperature, whereas, 288.2 MPa, ,207.7 MPa, and 7.8%, respectively, at 150℃. In comparison with the properties at room temperature, the tensile strength and yield strength are high and only decrease by 11.6% and 1.8% at 150℃. The M928i reinforced Mg-Al based composite possesses good heat resistance at 150℃. The excellent resistance to effect of heat is attributed to the high melting tempera- ture and good thermal stability of fine Mg2Si phases, which are distributed uniformly in the composite, and effectively hinder the grain boundary gliding and dislocation movement.展开更多
Recent studies have shown that 3D printed scaffolds integrated with growth factors can guide the growth of neurites and promote axon regeneration at the injury site.However,heat,organic solvents or cross-linking agent...Recent studies have shown that 3D printed scaffolds integrated with growth factors can guide the growth of neurites and promote axon regeneration at the injury site.However,heat,organic solvents or cross-linking agents used in conventional 3D printing reduce the biological activity of growth factors.Low temperature 3D printing can incorporate growth factors into the scaffold and maintain their biological activity.In this study,we developed a collagen/chitosan scaffold integrated with brain-derived neurotrophic factor(3D-CC-BDNF)by low temperature extrusion 3D printing as a new type of artificial controlled release system,which could prolong the release of BDNF for the treatment of spinal cord injury(SCI).Eight weeks after the implantation of scaffolds in the transected lesion of T10 of the spinal cord,3D-CC-BDNF significantly ameliorate locomotor function of the rats.Consistent with the recovery of locomotor function,3D-CC-BDNF treatment could fill the gap,facilitate nerve fiber regeneration,accelerate the establishment of synaptic connections and enhance remyelination at the injury site.展开更多
Hydrostatic cyclic expansion extrusion(HCEE) process at elevated temperatures is proposed as a method for processing less deformable materials such as magnesium and for producing long ultrafine-grained rods. In the HC...Hydrostatic cyclic expansion extrusion(HCEE) process at elevated temperatures is proposed as a method for processing less deformable materials such as magnesium and for producing long ultrafine-grained rods. In the HCEE process at elevated temperatures, high-pressure molten linear low-density polyethylene(LLDPE) was used as a fluid to eliminate frictional forces. To study the capability of the process,AM60 magnesium rods were processed and the properties were investigated. The mechanical properties were found to improve significantly after the HCEE process. The yield and ultimate strengths increased from initial values of 138 and 221 MPa to 212 and 317 MPa, respectively.Moreover, the elongation was enhanced due to the refined grains and the existence of high hydrostatic pressure. Furthermore, the microhardness was increased from HV 55.0 to HV 72.5. The microstructural analysis revealed that ultrafine-grained structure could be produced by the HCEE process. Moreover, the size of the particles decreased, and these particles thoroughly scattered between the grains. Finite element analysis showed that the HCEE was independent of the length of the sample, which makes the process suitable for industrial applications.展开更多
Microstructure,texture,and mechanical properties of the extruded Mg-2.49Nd-1.82Gd-0.2Zn-0.2Zr alloy were investigated at different extrusion temperatures(260 and 320℃),extrusion ratios(10:1,15:1,and 30:1),and extrusi...Microstructure,texture,and mechanical properties of the extruded Mg-2.49Nd-1.82Gd-0.2Zn-0.2Zr alloy were investigated at different extrusion temperatures(260 and 320℃),extrusion ratios(10:1,15:1,and 30:1),and extrusion speeds(3 and 6 mm/s).The experimental results exhibited that the grain sizes after extrusion were much finer than that of the homogenized alloy,and the second phase showed streamline distribution along the extrusion direction(ED).With extrusion temperature increased from 260 to 320℃,the microstructure,texture,and mechanical properties of alloys changed slightly.The dynamic recrystallization(DRX)degree and grain sizes enhanced as the extrusion ratio increased from 10:1 to 30:1,and the strength gradually decreased but elongation(EL)increased.With the extrusion speed increased from 3 to 6 mm/s,the grain sizes and DRX degree increased significantly,and the samples presented the typical<2111>-<1123>rare-earth(RE)textures.The alloy extruded at 260℃ with extrusion ratio of 10:1 and extrusion speed of 3 mm/s showed the tensile yield strength(TYS)of 213 MPa and EL of 30.6%.After quantitatively analyzing the contribution of strengthening mechanisms,it was found that the grain boundary strengthening and dislocation strengthening played major roles among strengthening contributions.These results provide some guidelines for enlarging the industrial application of extruded Mg-RE alloy.展开更多
基金This study was financially supported by the Scientific Research Project of Education Department of Shaanxi Province （No. 07JK358）；the National Natural Science Foundation of China （No.50271054）； the Shaanxi Provincial Natural Scientific Research Project （No.2003E111）； SRF for ROCS, SEM （101-220325）.
文摘M92Si reinforced Mg-Al based composite with high amount o/silicon was prepared by permanent mould casting, and then extruded by reciprocating extrusion （RE） after the composite was processed by homogenization heat treatment. The effect of RE processing on the morphology and size of M92Si and the mechanical properties of the com- posite were investigated, to develop new ways to refine the M928i phase and improve its shape. The result showed that RE was very useful in refining the M92Si phase. The more the RE processing passes, the better the refining effect would be. Moreover, the uniform distribution of M928i phases would be more in the composite. After the composite was processed by RE for 12 passes, most M92Si phases were equiaxed, with granular diameter below 20 μm, and distributed uniformly in the matrix of the composite. The mechanical properties of the composite could be increased prominently by RE processing, and were much higher than that in the as-cast state. As the temperature rises, the tensile strength is reduced. For the composite RE processed for 12 passes, the tensile strength, yield strength, and elongation are 325.9 MPa, 211.4 MPa, and 3.3% at room temperature, whereas, 288.2 MPa, ,207.7 MPa, and 7.8%, respectively, at 150℃. In comparison with the properties at room temperature, the tensile strength and yield strength are high and only decrease by 11.6% and 1.8% at 150℃. The M928i reinforced Mg-Al based composite possesses good heat resistance at 150℃. The excellent resistance to effect of heat is attributed to the high melting tempera- ture and good thermal stability of fine Mg2Si phases, which are distributed uniformly in the composite, and effectively hinder the grain boundary gliding and dislocation movement.
基金supported by the National Nature Scientific Fund of China(81771352,81971782,81771350)the Nature Scientific Fund of Tianjin(18JCJQJC48500,19JCYBJC27900).
文摘Recent studies have shown that 3D printed scaffolds integrated with growth factors can guide the growth of neurites and promote axon regeneration at the injury site.However,heat,organic solvents or cross-linking agents used in conventional 3D printing reduce the biological activity of growth factors.Low temperature 3D printing can incorporate growth factors into the scaffold and maintain their biological activity.In this study,we developed a collagen/chitosan scaffold integrated with brain-derived neurotrophic factor(3D-CC-BDNF)by low temperature extrusion 3D printing as a new type of artificial controlled release system,which could prolong the release of BDNF for the treatment of spinal cord injury(SCI).Eight weeks after the implantation of scaffolds in the transected lesion of T10 of the spinal cord,3D-CC-BDNF significantly ameliorate locomotor function of the rats.Consistent with the recovery of locomotor function,3D-CC-BDNF treatment could fill the gap,facilitate nerve fiber regeneration,accelerate the establishment of synaptic connections and enhance remyelination at the injury site.
基金This work was financially supported by the Iran National Science Foundation(No.96000854).
文摘Hydrostatic cyclic expansion extrusion(HCEE) process at elevated temperatures is proposed as a method for processing less deformable materials such as magnesium and for producing long ultrafine-grained rods. In the HCEE process at elevated temperatures, high-pressure molten linear low-density polyethylene(LLDPE) was used as a fluid to eliminate frictional forces. To study the capability of the process,AM60 magnesium rods were processed and the properties were investigated. The mechanical properties were found to improve significantly after the HCEE process. The yield and ultimate strengths increased from initial values of 138 and 221 MPa to 212 and 317 MPa, respectively.Moreover, the elongation was enhanced due to the refined grains and the existence of high hydrostatic pressure. Furthermore, the microhardness was increased from HV 55.0 to HV 72.5. The microstructural analysis revealed that ultrafine-grained structure could be produced by the HCEE process. Moreover, the size of the particles decreased, and these particles thoroughly scattered between the grains. Finite element analysis showed that the HCEE was independent of the length of the sample, which makes the process suitable for industrial applications.
基金supported by the National Science and Technology Major Project,China(No.2019-VI-0004-0118)the National Natural Science Foundation of China(No.51771152)the National Key R&D Program of China(No.2018YFB1106800)。
文摘Microstructure,texture,and mechanical properties of the extruded Mg-2.49Nd-1.82Gd-0.2Zn-0.2Zr alloy were investigated at different extrusion temperatures(260 and 320℃),extrusion ratios(10:1,15:1,and 30:1),and extrusion speeds(3 and 6 mm/s).The experimental results exhibited that the grain sizes after extrusion were much finer than that of the homogenized alloy,and the second phase showed streamline distribution along the extrusion direction(ED).With extrusion temperature increased from 260 to 320℃,the microstructure,texture,and mechanical properties of alloys changed slightly.The dynamic recrystallization(DRX)degree and grain sizes enhanced as the extrusion ratio increased from 10:1 to 30:1,and the strength gradually decreased but elongation(EL)increased.With the extrusion speed increased from 3 to 6 mm/s,the grain sizes and DRX degree increased significantly,and the samples presented the typical<2111>-<1123>rare-earth(RE)textures.The alloy extruded at 260℃ with extrusion ratio of 10:1 and extrusion speed of 3 mm/s showed the tensile yield strength(TYS)of 213 MPa and EL of 30.6%.After quantitatively analyzing the contribution of strengthening mechanisms,it was found that the grain boundary strengthening and dislocation strengthening played major roles among strengthening contributions.These results provide some guidelines for enlarging the industrial application of extruded Mg-RE alloy.
