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Minimally Invasive Surgery for Necrotizing Pancreatitis: A Case Report
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作者 Néstor Veriel Méndez Huerta Luis Fernando Zorrilla Núñez +6 位作者 Noelia Obregón Gaxiola César Jair Treviño Arizmendi Gerardo Iván Muñoz Morales Marco Alejandro Arizmendi Villarreal Pamela Denisse Valdez Navarro Marco Antonio Hernández Guedea Gerardo Enrique Muñoz Maldonado 《Surgical Science》 2024年第9期514-521,共8页
Introduction: Necrotizing pancreatitis management is complex and varies significantly among clinicians. Minimally invasive approaches like transgastric necrosectomy via laparoscopy are emerging as effective treatment ... Introduction: Necrotizing pancreatitis management is complex and varies significantly among clinicians. Minimally invasive approaches like transgastric necrosectomy via laparoscopy are emerging as effective treatment options. This case report underscores the technique’s efficacy, clinical outcomes, and role in reducing complications. Clinical Observation: A 59-year-old male with a history of smoking and alcoholism presented with severe abdominal pain, nausea, and vomiting. Over the following weeks, he developed symptoms including asthenia, weight loss, and melena. Diagnostic workup revealed severe anemia and Balthazar E necrotizing pancreatitis, with significant intra-abdominal fluid collections and signs of infection. After initial conservative management, the patient underwent transgastric necrosectomy via laparoscopy due to deteriorating clinical status. The procedure involved removing necrotic tissue and performing a cystogastroanastomosis and jejunostomy. Postoperative care included fasting, parenteral nutrition, broad-spectrum antibiotics, and enzymatic replacement. The patient recovered well, with reduced necrotic tissue on follow-up imaging, and was discharged twelve days post-surgery [1]. Conclusion: Transgastric necrosectomy by laparoscopy is a valuable first-line surgical option for patients with symptomatic necrotizing pancreatitis, particularly in cases without prior interventions. This minimally invasive technique helps reduce major complications and mortality, offering a less invasive alternative to traditional open necrosectomy. The multidisciplinary approach and careful postoperative management were crucial to the patient’s favorable outcome. The case highlights the potential of transgastric necrosectomy as an effective treatment strategy in managing complex pancreatitis cases, including those with associated duodenal perforation [2]. 展开更多
关键词 NECROTIZING transgastric PANCREATIC NECROSECTOMY PANCREATITIS Case Report
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Infection during transgastric and transvaginal natural orifice transluminal endoscopic surgery in a live porcine model 被引量:6
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作者 YANG Qing-yun ZHANG Guang-yong +5 位作者 WANG Lei WANG Zhi-gang LI Feng LI Yan-qing DING Xiang-jiu HU San-yuan 《Chinese Medical Journal》 SCIE CAS CSCD 2011年第4期556-561,共6页
Background The infection risk of natural orifice transluminal endoscopic surgery (NOTES) is of concern. The aim of this study was to assess the safety of NOTES by investigating the intraperitoneal bacterial load dur... Background The infection risk of natural orifice transluminal endoscopic surgery (NOTES) is of concern. The aim of this study was to assess the safety of NOTES by investigating the intraperitoneal bacterial load during transgastric and transvaginal procedures with antiseptic or controling perioperative preparation.Methods Forty-five female pigs were randomly assigned to five equal groups: the transgastric (TG) control group (group A), the TG middle volume gastric lavage group (group B), the TG high volume lavage group (group C), the transvaginal (TV) control group (group D) and the TV study group (group E). The study groups received gastric or vaginal lavage and abdominal antimicrobial irrigation, while the control groups received neither. All animals were administered intravenous antibiotics, underwent NOTES peritoneoscopy and transumbilical laparoscopic cholecystectomy under NOTES view with sterile instruments. The viscerotomy was closed by laparoscopic suture. The animals were observed until necropsy was performed 14 days postoperatively. Quantitative bacteriologic cultures were taken from the gastric or vaginal aspirate before and after lavage; peritoneal fluid was collected before and after peritoneal irrigation and at necropsy. Results The surgical procedures were completed for all the pigs and all of them survived. The mean operative time of the TG group and the TV group was (81±27) minutes and (66±12) minutes, respectively. All animals survived for 14 days.At necropsy, significantly more peritoneal infections were noted in group A than in group D (5:9 vs. 0:9; P 〈0.05). Nogross evidence of intra-peritoneal infection was found in groups B, C, D and E. Bacteriological evidence was seen in all pigs in group A, 7 pigs in group B, 6 pigs in group D, and none in groups C and E.Conclusions Without gastric or vaginal lavage and antibiotic peritoneal irrigation, the TG procedure has a higher infection rate than the TV access. After antiseptic preparation, the b 展开更多
关键词 LAPAROSCOPY natural orifice transluminal endoscopic surgery transgastric surgery transvaginal surgery INFECTION
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超声内镜下经胃、十二指肠乳头引流治疗胰腺假性囊肿的效果评价 被引量:7
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作者 王道蓉 吕龙 +1 位作者 高山 张卫国 《中国内镜杂志》 北大核心 2016年第8期83-86,共4页
目的探究超声内镜(EUS)下经胃或十二指肠乳头置管引流治疗胰腺假性囊肿(PPC)的临床疗效。方法选取2012年3月-2015年3月该院收治的100例PPC患者,按临床治疗指标对其中的80例进行EUS下经胃穿刺置管引流,20例行EUS下经十二指肠乳头穿刺置... 目的探究超声内镜(EUS)下经胃或十二指肠乳头置管引流治疗胰腺假性囊肿(PPC)的临床疗效。方法选取2012年3月-2015年3月该院收治的100例PPC患者,按临床治疗指标对其中的80例进行EUS下经胃穿刺置管引流,20例行EUS下经十二指肠乳头穿刺置管引流。记录所有患者的治疗效果以及并发症的发生情况。结果 100例患者的手术中成功率为95.00%,其中囊肿完全消失率为84.00%。100例患者中共有10例发生术中出血,3例发生支架移位堵塞,另有7例术后出现囊肿内部感染,并发症的发生率为20.00%。结论对PPC患者进行EUS下经胃、十二指肠乳头穿刺置管引流治疗可以提高临床疗效,减少并发症,值得在临床上推广应用。 展开更多
关键词 超声内镜 十二指肠 胰腺假性囊肿
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Endoscopic transgastric drainage of a gastric wall abscess after endoscopic submucosal dissection 被引量:4
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作者 Osamu Dohi Moyu Dohi +3 位作者 Ken Inoue Yasuyuki Gen Masayasu Jo Kazuhiko Tokita 《World Journal of Gastroenterology》 SCIE CAS 2014年第4期1119-1122,共4页
A 63-year-old woman was referred to our hospital for further examination because of an incidental finding of early gastric cancer.Endoscopic submucosal dissection(ESD)was successfully performed for complete resection ... A 63-year-old woman was referred to our hospital for further examination because of an incidental finding of early gastric cancer.Endoscopic submucosal dissection(ESD)was successfully performed for complete resection of the tumor.On the first post-ESD day,the patient suddenly complained of abdominal pain after an episode of vomiting.Abdominal computed tomography(CT)showed delayed perforation after ESD.The patient was conservatively treated with an intravenous proton pump inhibitor and antibiotics.On the fifth post-ESD day,CT revealed a gastric wall abscess in the gastric body.Gastroscopy revealed a gastric fistula at the edge of the post-ESD ulcer,and pus was found flowing into the stomach.An intradrainage stent and an extradrainage nasocystic catheter were successfully inserted into the abscess for endoscopic transgastric drainage.After the procedure,the clinical symptoms and laboratory test results improved quickly.Two months later,a follow-up CT scan showed no collection of pus.Consequently,the intradrainage stent was removed.Although the gastric wall abscess recurred 2 wk after stent removal,it recovered soon after endoscopic transgastric drainage.Finally,after stent removal and oral antibiotic treatment for 1 mo,no recurrence of the gastric wall abscess was found. 展开更多
关键词 Gastric wall abscess transgastric drainage Delayed perforation Endoscopic submucosal dissection Early gastric cancer
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Endoscopic transgastric fenestration versus percutaneous drainage for management of(peri)pancreatic fluid collections adjacent to gastric wall(with video) 被引量:2
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作者 Hong-Mei Zhang Hui-Ting Ke +7 位作者 Md Robin Ahmed Ya-Juan Li Ghulam Nabi Mu-Han Li Ji-Yu Zhang Dan Liu Li-Xia Zhao Bing-Rong Liu 《World Journal of Gastroenterology》 SCIE CAS 2023年第40期5557-5565,共9页
BACKGROUND Percutaneous drainage(PCD)and endoscopic approaches have largely replaced surgical drainage as the initial approach for(peri)pancreatic fluid collections(PFC)s,while complications associated with endoscopic... BACKGROUND Percutaneous drainage(PCD)and endoscopic approaches have largely replaced surgical drainage as the initial approach for(peri)pancreatic fluid collections(PFC)s,while complications associated with endoscopic stent implantation are common.AIM To introduce a novel endoscopic therapy named endoscopic transgastric fenestration(ETGF),which involves resection of tissue by endoscopic accessory between gastric and PFCs without stent implantation,and to evaluate its efficacy and safety compared with PCD for the management of PFCs adjacent to the gastric wall.METHODS Patients diagnosed with PFCs adjacent to the gastric wall and who subsequently received ETGF or PCD were restrospectively enrolled.Indications for intervention were consistent with related guidelines.We analyzed patients baseline characteristics,technical and clinical success rate,recurrence and reintervention rate,procedure-related complications and adverse events.RESULTS Seventy-two eligible patients were retrospectively identified(ETGF=34,PCD=38)from October 2017 to May 2021.Patients in the ETGF group had a significantly higher clinical success rate than those in the PCD group(97.1 vs 76.3%,P=0.01).There were no statistically significant differences regarding recurrence,reintervention and incidence of complication between the two groups.While long-term catheter drainage was very common in the PCD group.CONCLUSION Compared with PCD,ETGF has a higher clinical success rate in the management of PFCs adjacent to the gastric wall.ETGF is an alternative effective strategy for the treatment of PFCs adjacent to the gastric wall. 展开更多
关键词 (Peri)Pancreatic fluid collections Endoscopic transgastric fenestration Percutaneous drainage
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Natural orifice transluminal endoscopy surgery:A review 被引量:5
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作者 Joo Moreira-Pinto Estevo Lima +1 位作者 Jorge Correia-Pinto Carla Rolanda 《World Journal of Gastroenterology》 SCIE CAS CSCD 2011年第33期3795-3801,共7页
Minimally invasive surgery started spreading worldwide in 1987,when the first laparoscopic cholecystectomy was performed.Meanwhile,improvement of endoscopic equipment and instruments allowed gastroenterologists to att... Minimally invasive surgery started spreading worldwide in 1987,when the first laparoscopic cholecystectomy was performed.Meanwhile,improvement of endoscopic equipment and instruments allowed gastroenterologists to attempt more aggressive endoluminal interventions,even beyond the wall barrier.The first transgastric peri-toneoscopy,in 2004,brought to light the concept of natural orifice transluminal endoscopic surgery(NOTES).The idea of incisionless surgery is attractive and has become a new goal for both surgeons and other people interested in this field of investigation.The authors present a review of all developments concerning NOTES,including animal studies and human experience. 展开更多
关键词 TRANSESOPHAGEAL transgastric Transvesical TRANSVAGINAL Transcolonic Natural orifice trans-luminal endoscopic surgery Minimally invasive tech-niques
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NOTES经胃入路诊断不明原因腹水的临床研究 被引量:5
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作者 唐静 杨丹 +6 位作者 吴涛 沈文拥 卢丹萍 魏沙 薛焱 杨美华 刘爱民 《重庆医学》 CAS 北大核心 2017年第12期1619-1620,1623,共3页
目的探讨经自然腔道内镜外科(NOTES)经胃入路对不明原因腹水的病因诊断的临床价值。方法回顾该院2015年11月至2016年7月采用经胃入路NOTES诊断12例不明原因腹水患者进行腹腔探查及腹膜活检的临床资料,通过对术后有无并发症发生及疾病诊... 目的探讨经自然腔道内镜外科(NOTES)经胃入路对不明原因腹水的病因诊断的临床价值。方法回顾该院2015年11月至2016年7月采用经胃入路NOTES诊断12例不明原因腹水患者进行腹腔探查及腹膜活检的临床资料,通过对术后有无并发症发生及疾病诊断率进行分析统计,评估该手术风险及临床应用价值。结果通过腹腔探查、腹膜活检后病理学证实,确诊率达100%,其中结核性腹膜炎8例(66.7%)、肝硬化2例(16.7%)、腹膜间皮瘤1例(8.3%)、转移性腹膜癌1例(8.3%);术后出现腹痛2例,其中1例中性粒细胞比值升高,症状及实验室指标异常持续时间均未超过24h,发生率为8.3%;无术后腹腔感染、切口出血、穿刺口瘘等并发症发生。结论 NOTES经胃入路腹腔探查及腹膜活检诊断不明原因腹水,具有创伤小、并发症少、术后恢复快等优势,具有重要的临床应用价值。 展开更多
关键词 经自然腔道内镜外科 经胃 腹膜活检 腹水
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Comparison of trans-gastric vs trans-enteric(trans-duodenal or trans-jejunal)endoscopic ultrasound guided gallbladder drainage using lumen apposing metal stents
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作者 Dheera Grover Ifrah Fatima Murali Dharan 《World Journal of Gastrointestinal Endoscopy》 2023年第9期574-583,共10页
BACKGROUND Endoscopic ultrasound guided gallbladder drainage(EUS-GBD)is being increasingly used in practice(either as a bridge to cholecystectomy in high-risk patients or as destination therapy in non-surgical patient... BACKGROUND Endoscopic ultrasound guided gallbladder drainage(EUS-GBD)is being increasingly used in practice(either as a bridge to cholecystectomy in high-risk patients or as destination therapy in non-surgical patients).Stents are used to create a conduit between the lumen of the gallbladder(GB)and the intestinal lumen through the gastric or enteric routes.Among the various types of stents used,cautery-enhanced lumen apposing metallic stents(LAMS)may be associated with fewer adverse events(AEs).AIM To compare the clinical success,technical success,and rate of AEs between transgastric(TG)and trans-enteric[transduodenal(TD)/transjejunal(TJ)]approach to GB drainage.Further,we analyzed whether using cautery enhanced stents during EUS-GBD impacts the above parameters.METHODS Study was registered in PROSPERO(CRD42022319019)and comprehensive literature review was conducted.Manuscripts were reviewed for the data collection:Rate of AEs,clinical success,and technical success.Random effects model was utilized for the analysis.RESULTS No statistically significant difference in clinical and technical success between the TD/TJ and TG approaches(P>0.05)were noted.There was no statistically significant difference in the rate of AEs when comparing two-arm studies only.However,when all studies were included in the analysis difference was almost significant favoring the TD/TJ approach.When comparing cautery-enhanced LAMS with non-cautery enhanced LAMS,a statistically significant difference in the rate of AEs was observed when all the studies were included,with the rate being higher in non-cautery enhanced stents(14.0%vs 37.8%;P<0.01).CONCLUSION As per our study results,TD/TJ approach appears to be associated with lower rate of adverse events and comparable efficacy when compared to the TG approach for the EUS-GBD.Additionally,use of cautery-enhanced LAMS for EUS-GBD is associated with a more favorable adverse event profile compared to cold LAMS.Though the approach chosen depends on several patient and physician factors,the above fi 展开更多
关键词 Transduodenal transgastric CAUTERY Endoscopic ultrasound guided gallbladder drainage AXIOS
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Endoscopic ultrasound-guided biliary drainage:Are we there yet? 被引量:2
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作者 Rishi Pawa Troy Pleasant +1 位作者 Chloe Tom Swati Pawa 《World Journal of Gastrointestinal Endoscopy》 2021年第8期302-318,共17页
Endoscopic retrograde cholangiopancreatography(ERCP)is the mainstay procedure of choice for management of obstructive biliary disease.While ERCP is widely performed with high success rates,the procedure is not feasibl... Endoscopic retrograde cholangiopancreatography(ERCP)is the mainstay procedure of choice for management of obstructive biliary disease.While ERCP is widely performed with high success rates,the procedure is not feasible in every patient such as cases of non-accessible papilla.In the setting of unsuccessful ERCP,endoscopic ultrasound-guided biliary drainage(EUS-BD)has become a promising alternative to surgical bypass and percutaneous biliary drainage(PTBD).A variety of different forms of EUS-BD have been described,allowing for both intrahepatic and extrahepatic approaches.Recent studies have reported high success rates utilizing EUS-BD for both transpapillary and transluminal drainage,with fewer adverse events when compared to PTBD.Advancements in novel technologies designed specifically for EUS-BD have led to increased success rates as well as improved safety profile for the procedure.The techniques of EUS-BD are yet to be fully standardized and are currently performed by highly trained advanced endoscopists.The aim of our review is to highlight the different EUSguided interventions for achieving biliary drainage and to both assess the progress that has been made in the field as well as consider what the future may hold. 展开更多
关键词 Endoscopic ultrasound-guided biliary drainage Endoscopic ultrasound-guided rendezvous Endoscopic ultrasound-guided choledochoduodenostomy Endoscopic ultrasound-guided hepaticogastrostomy Endoscopic ultrasound-guided gallbladder drainage Endoscopic ultrasound-directed transgastric endoscopic retrograde cholangiopancreatography
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腹腔镜下胃肿瘤外翻切除术在特殊部位胃间质瘤患者中的应用 被引量:2
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作者 陶克龙 徐关根 +3 位作者 陶锋 叶民峰 李尧清 季科炜 《浙江临床医学》 2020年第10期1489-1491,共3页
目的探讨腹腔镜下胃肿瘤外翻切除术治疗特殊部位(肿瘤距离贲门或幽门≤5cm)胃间质瘤的安全性和可行性。方法回顾性分析2014年9月至2019年12月接受腹腔镜下胃肿瘤外翻切除术治疗的30例特殊部位胃间质瘤(肿瘤距离贯门或幽门≤5cm)患者的... 目的探讨腹腔镜下胃肿瘤外翻切除术治疗特殊部位(肿瘤距离贲门或幽门≤5cm)胃间质瘤的安全性和可行性。方法回顾性分析2014年9月至2019年12月接受腹腔镜下胃肿瘤外翻切除术治疗的30例特殊部位胃间质瘤(肿瘤距离贯门或幽门≤5cm)患者的临床资料。结果30例特殊部位胃间质瘤患者中男13例,女17例,平均年龄64.3岁,肿瘤邻近贵门17例,邻近幽门13例,肿瘤直径(3.86±0.18)cm。所有患者均成功实行腹腔镜下胃肿瘤外翻切除术,手术过程中未出现患者需要中转开腹手术,手术时间(54.93±2.15)min,术中出血量(25.83±2.50)ml,术后首次排气时间(2.70±0.14)d,首次进食流质时间(2.07±0.12)d,术后住院天数(5.9±0.16)d。所有患者均无明显并发症发生,经过3~66个月的随访,无一例复发。结论腹腔镜下胃肿瘤外翻切除术治疗特殊部位胃间质瘤是安全、可行的。 展开更多
关键词 胃间质瘤 腹腔镜 胃肿瘤外翻切除术
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Snare-assisted flexible endoscope in trans-gastric endoscopic gallbladder-preserving surgery:A pilot animal study
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作者 Xian-Wen Guo Yun-Xiao Liang +3 位作者 Peng-Yu Huang Lie-Xin Liang Yi-Qing Zeng Zhen Ding 《World Journal of Gastroenterology》 SCIE CAS 2022年第19期2112-2122,共11页
BACKGROUND Natural orifice transluminal endoscopic surgery(NOTES)gallbladder-preserving surgery by flexible endoscopy is an emerging technology.However,the gallbladder fails to obtain traction and positioning function... BACKGROUND Natural orifice transluminal endoscopic surgery(NOTES)gallbladder-preserving surgery by flexible endoscopy is an emerging technology.However,the gallbladder fails to obtain traction and positioning functions during the operation.AIM To evaluate the feasibility and safety of a new surgical method,“snare-assisted pure NOTES gallbladder-preserving surgery”.METHODS Eight miniature pigs were randomly divided into the experimental group[NOTES gallbladder-preserving surgery using the snare device,snare assisted(SA)]and the control group(NOTES gallbladder-preserving surgery without using the snare device,NC),with four cases in each group.The differences between the two groups of animals in operating time,operating workload,complications,adverse events,white blood cells,and liver function were determined.RESULTS No differences were found in the surgical success rate,gallbladder incision closure,white blood cell count,or liver function between the two groups.The total operating time,gallbladder incision blood loss,gallbladder disorientation time,gallbladder incision closure time,and workload scores on the National Aeronautics and Space Administration-Task Load Index were significantly reduced in the SA group(P<0.05).CONCLUSION These results indicated that snare-assisted pure NOTES gallbladder-preservation surgery using standard endoscopic instruments reduced the difficulty of operation,shortened operation time,and did not increase complications in pigs.A new method for pure NOTES gallbladder-preservation surgery was provided. 展开更多
关键词 SNARE Flexible endoscope Endoscopic gallbladder-preserving surgery Natural orifice transluminal endoscopic surgery transgastric Minimally invasive
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Endoscopic approach to gastric remnant outlet obstruction after gastric bypass:A case report
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作者 Arash Zarrin Sufian Sorathia +2 位作者 Vivek Choksi Steven Robert Kaplan Franklin Kasmin 《World Journal of Gastrointestinal Endoscopy》 CAS 2020年第9期297-303,共7页
BACKGROUND Acute gastric remnant bleeding is a rare complication of bariatric surgery.Furthermore,acute bleeding from the gastric remnant resulting in gastric remnant outlet obstruction has not been described previous... BACKGROUND Acute gastric remnant bleeding is a rare complication of bariatric surgery.Furthermore,acute bleeding from the gastric remnant resulting in gastric remnant outlet obstruction has not been described previously.Endoscopic management of gastric remnant bleed has been challenging due to difficulty accessing the excluded stomach.Traditionally,this necessitates surgical intervention.Recently,however,the adoption of endoscopic ultrasound-directed transgastric intervention provides an alternative approach to management.CASE SUMMARY A 65-year-old male with a prior gastric bypass presented with the sudden onset of progressive abdominal distension,nausea,and melena of two days duration.His imaging illustrated a massively distended stomach.A nasogastric tube did not result in drainage of fluid or decompression of his abdomen.His endoscopy revealed a normal-appearing gastro-jejunal anastomosis and confirmed the distended"fluid"-filled gastric remnant.An endoscopic ultrasound-directed gastrogastrostomy was created to decompress the gastric remnant.Two liters of blood was suctioned before a large adherent clot was visualized in the gastric antrum.The patient underwent emergent angiography with embolization of the gastroduodenal artery.He was discharged with a stable hemoglobin level and resolution of symptoms.Healing superficial gastric ulcers were visualized on a follow-up endoscopy.Gastric biopsies were consistent with Helicobacter pylori infection for which the patient was treated,and successful eradication was achieved.CONCLUSION This patient benefited from a timely diagnosis and effective therapy of an acute gastric remnant obstruction from a bleeding ulcer with endoscopic ultrasound directed transgastric intervention. 展开更多
关键词 Gastrointestinal bleeding Gastric outlet obstruction Gastric remnant Endoscopic ultrasound directed transgastric intervention Gastrogastrostomy Case report
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经胃、结肠联合路径腹腔内镜探查术的实验研究 被引量:36
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作者 李闻 孙刚 +3 位作者 王向东中国人民解放军总医院消化科 王敬 孙国辉 杨云生 《中华消化内镜杂志》 2007年第6期401-405,共5页
目的初步探讨经胃(口)和经结肠(肛)双路径经自然孔道内镜外科学(NOTES)技术的可行性和利弊。方法采用雌性猪模型。先经口路径用针刀在胃前壁穿透切开,用扩张球囊扩大通道,将胃镜送入腹腔,在经胃路径的内镜监视下,再经肛路径用针刀穿透... 目的初步探讨经胃(口)和经结肠(肛)双路径经自然孔道内镜外科学(NOTES)技术的可行性和利弊。方法采用雌性猪模型。先经口路径用针刀在胃前壁穿透切开,用扩张球囊扩大通道,将胃镜送入腹腔,在经胃路径的内镜监视下,再经肛路径用针刀穿透结肠壁,用弓刀扩大肠壁切口,将内镜送入腹腔。两条内镜先分别单独寻找胆囊和输卵管,然后相互配合共同寻找和观察胆囊和输卯管。胃肠切口分别用止血夹闭合。术后立即剖腹探查,观察腹腔内脏器损伤及胃肠壁切口闭合情况。结果胃肠壁通过球囊和弓刀扩大切口均无出血。经胃壁穿透切开时损伤肝脏表面。在经胃路径的内镜监视下完成结肠壁切开,避免了临近脏器的损伤。单内镜寻找胆囊和输卵管困难,时间较长。而双内镜配合寻找胆囊和输卵管相对容易,时间缩短,视野暴露好。用止血夹封闭胃壁切口比结肠切口困难。结论经胃与经结肠联合路径腹腔内镜探查术是可行的,可能比单路径更容易完成NOTES 操作。 展开更多
关键词 内窥镜外科手术 经胃路径 经结肠路径
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经胃内镜肝囊肿开窗术(附1例报告) 被引量:32
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作者 王东 陈丹磊 +5 位作者 于恩达 吴仁培 杨丽 郑永志 郑成竹 李兆申 《中国实用外科杂志》 CSCD 北大核心 2009年第5期440-443,共4页
外科手术是治疗疾病的重要手段,但又同时给病人带来创伤和痛苦。医生、病人及其家属的愿望是在安全治疗疾病的前提下,减轻疼痛,减少瘢痕或无瘢痕。目前,以腹腔镜技术为代表的微创外科技术日臻成熟。同时,内镜医师也在尝试在诊断性... 外科手术是治疗疾病的重要手段,但又同时给病人带来创伤和痛苦。医生、病人及其家属的愿望是在安全治疗疾病的前提下,减轻疼痛,减少瘢痕或无瘢痕。目前,以腹腔镜技术为代表的微创外科技术日臻成熟。同时,内镜医师也在尝试在诊断性内镜基础上开展治疗性内镜技术。在此基础上一些学者提出经自然孔道内镜外科(natural orifice transluminal endoscopic surgery。NOTES)的概念,即:通过人体的自然孔道如口腔、肛门、尿道及阴道等置入软性内镜,分别穿刺空腔脏器如胃、直肠、膀胱及阴道后壁等到达腹膜腔, 展开更多
关键词 内镜外科手术 经自然孔道内镜外科 经胃路径 肝囊肿开窗术
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腹腔镜下完全腹膜外疝修补术与经腹腔腹膜前疝修补术治疗成人单侧初发腹股沟疝的效果比较 被引量:23
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作者 张敏剑 吴永友 +2 位作者 钟丰云 吴伟兵 李嘉 《中国医药导报》 CAS 2023年第10期84-87,99,共5页
目的比较腹腔镜下完全腹膜外疝修补术(TEP)与经腹腔腹膜前疝修补术(TAPP)治疗成人单侧初发腹股沟疝的临床效果。方法选取2019年5月至2021年6月江苏省太仓市中医医院收治的82例单侧初发腹股沟疝患者为研究对象,采用随机数字表法将其分为... 目的比较腹腔镜下完全腹膜外疝修补术(TEP)与经腹腔腹膜前疝修补术(TAPP)治疗成人单侧初发腹股沟疝的临床效果。方法选取2019年5月至2021年6月江苏省太仓市中医医院收治的82例单侧初发腹股沟疝患者为研究对象,采用随机数字表法将其分为TEP组(给予TEP治疗)和TAPP组(给予TAPP治疗),每组41例。比较两组手术相关指标、住院费用、血气变化指标[手术前后动脉血二氧化碳分压差值(ΔPaCO_(2))、术中经皮二氧化碳分压监测(TcCO_(2))最大值与术前TcCO_(2)的差值(ΔTcCO_(2))、达到TcCO_(2)最大值的时间(T_(max))]、术后疼痛情况、术后并发症及术后6个月复发情况。结果TEP组手术时间、Tmax短于TAPP组,住院费用低于TAPP组,ΔPaCO_(2)、ΔTcCO_(2)均高于TAPP组,差异有统计学意义(P<0.05)。两组术中失血量、住院时间、疼痛持续时间、术后24 h视觉模拟评分法评分、术后并发症总发生率、术后6个月复发率比较,差异无统计学意义(P>0.05)。结论成人单侧初发腹股沟疝采用TEP在手术时间、住院费用方面优于TAPP,在减少手术中体内二氧化碳方面TAPP具有优势,两种手术方式治疗成人单侧初发腹股沟疝术后疼痛情况相近,且均安全、有效。 展开更多
关键词 单侧初发腹股沟疝 完全腹膜外疝修补术 经腹腔腹膜前疝修补术 临床效果
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经自然腔道内镜手术的实验研究 被引量:19
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作者 王东 郑永志 +2 位作者 吴仁培 于恩达 李兆申 《中华消化内镜杂志》 北大核心 2009年第1期6-10,共5页
目的初步探讨利用现有内镜器械经自然腔道内镜手术(NOTES)技术的可行性和安全性。方法采用6头雌性猪模型。经胃时首先用针刀在管壁穿透切开,ERCP拉式切开刀扩大切口,再用扩张气囊扩大通道,将胃镜送入腹腔。内镜在腹腔内寻找腹腔内... 目的初步探讨利用现有内镜器械经自然腔道内镜手术(NOTES)技术的可行性和安全性。方法采用6头雌性猪模型。经胃时首先用针刀在管壁穿透切开,ERCP拉式切开刀扩大切口,再用扩张气囊扩大通道,将胃镜送入腹腔。内镜在腹腔内寻找腹腔内器官,管壁切口用止血夹闭合,或自然旷置。NOTES术后1周经阴道切口进入腹腔观察;术后2周经胃壁其他部位切口重新进入腹腔观察,2例进行肝脏部分切除术;术后4周处死、解剖动物,观察腹腔内粘连、脏器损伤及管壁切口闭合情况。结果经胃壁进入腹腔12次,经阴道进入腹腔6次。经胃进入腹腔的平均时间为(33.4±10.9)min,经阴道平均时间为(10.1±2.5)min。用止血夹封闭胃壁切口或切口旷置,管壁切口均愈合良好,无明显并发症出现。再次腹腔探查时发现腹腔内有不同程度腹腔粘连,无腹腔脏器损伤。2例部分肝脏切除,1例出现膈肌损伤及死亡,1例成功。进入腹腔时出现切口出血2次,均为经胃切口时发生。出现腹腔脓肿1例。结论经胃、经阴道腹腔内镜探查及肝脏部分切除术是可行的,安全性较高,但NOTES专用器械的研发是NOTES顺利进行和成功的关键。 展开更多
关键词 内窥镜外科手术 经自然腔道内窥镜手术 经胃路径 经阴道路径
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经自然腔道内镜胆囊切除术的实验研究 被引量:13
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作者 王东 郑永志 +2 位作者 吴仁培 于恩达 李兆申 《中华消化内镜杂志》 北大核心 2009年第9期480-484,共5页
目的初步评价经自然腔道内镜胆囊切除术不同方法的可行性和优缺点。方法采用8只雌性猪模型平均分为4组。单镜手术均为经阴道途径的双管道内镜,双镜联合时再经胃插入一条普通内镜协助。分为单条内镜法、经阴道和经胃双镜联合法、腹腔镜... 目的初步评价经自然腔道内镜胆囊切除术不同方法的可行性和优缺点。方法采用8只雌性猪模型平均分为4组。单镜手术均为经阴道途径的双管道内镜,双镜联合时再经胃插入一条普通内镜协助。分为单条内镜法、经阴道和经胃双镜联合法、腹腔镜抓钳辅助单条内镜法、单条带透明帽的内镜法4种不同方法进行胆囊切除术。先用针刀在管壁穿透切开,ERCP拉式切开刀扩大切口,再用扩张球囊扩大通道,将胃镜送入腹腔,内镜在腹腔内寻找胆囊并进行胆囊切除术。术后管壁切口用止血夹闭合。于术后1周处死解剖动物,观察腹腔内粘连,胆囊床,邻近脏器损伤及管壁切口闭合情况。结果使用单条内镜无法完成胆囊切除术;双镜联合及腹腔镜抓钳辅助有利于胆囊管及血管的分离,均只有1例成功,1例未能最终完成胆囊切除术;2例带透明帽的单条内镜法都成功完成了胆囊切除术。腹腔镜抓钳辅助出现1例出血,双镜联合出现1例胆囊破裂。结论经自然腔道内镜胆囊切除术是可行的,带透明帽的双管道内镜法是较理想的操作方法,专用新器械的开发是手术操作顺利进行和成功的关键。 展开更多
关键词 内窥镜外科手术 经自然腔道内窥镜手术 经胃路径 经阴道路径 胆囊切除术
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经膀胱和胃联合路径切除猪肾脏的初步尝试 被引量:9
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作者 杨波 王辉清 +4 位作者 王林辉 徐斌 肖亮 周铁 孙颖浩 《第二军医大学学报》 CAS CSCD 北大核心 2010年第6期642-645,共4页
目的探讨联合经膀胱和胃路径进行猪肾脏切除术的可行性,总结操作经验。方法选取3只雌香猪,在输尿管硬镜下剪开膀胱前壁,并置入自制经膀胱Trocar,建立经膀胱路径;在输尿管镜引导下,利用高频针状电刀穿刺胃壁,用球囊扩张后导入胃镜。在胃... 目的探讨联合经膀胱和胃路径进行猪肾脏切除术的可行性,总结操作经验。方法选取3只雌香猪,在输尿管硬镜下剪开膀胱前壁,并置入自制经膀胱Trocar,建立经膀胱路径;在输尿管镜引导下,利用高频针状电刀穿刺胃壁,用球囊扩张后导入胃镜。在胃镜的引导下,经膀胱Trocar放入腹腔镜超声刀、剪刀、钛夹,完成肾切除术。结果成功进行3只雌香猪6个肾脏的切除术,手术时间(132±10.5)min,无明显出血,无明显并发症发生。第1例雌香猪的右肾静脉在用超声刀离断时出现出血,以钛夹处理,后5例肾脏血管处理前均以钛夹阻断后剪刀离断。结论联合经膀胱和胃联合路径可顺利切除猪肾脏,但术后未取出肾脏和关闭膀胱及胃壁穿刺口,仍需进一步研究改进。 展开更多
关键词 经自然腔道内镜手术 经膀胱 经胃 肾切除术
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经胃自然腔道内镜手术中聚维酮碘溶液灌洗胃腔预防感染的临床研究 被引量:7
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作者 郑永志 王东 +5 位作者 李兆申 孔祥毓 龚燕芳 陈丹磊 杨丽 吴仁培 《中华消化内镜杂志》 2013年第10期564-568,共5页
目的评估聚维酮碘溶液灌洗胃腔在经胃自然腔道内镜手术(NOTES)感染预防中临床应用的安全性和有效性。方法以2009年3月至2010年6月行经胃NOTES的9位患者为研究对象,手术在腹腔镜手术室进行。随灭菌胃镜置入灭菌外套管,留取胃腔内液5m... 目的评估聚维酮碘溶液灌洗胃腔在经胃自然腔道内镜手术(NOTES)感染预防中临床应用的安全性和有效性。方法以2009年3月至2010年6月行经胃NOTES的9位患者为研究对象,手术在腹腔镜手术室进行。随灭菌胃镜置入灭菌外套管,留取胃腔内液5ml(标本A);吸净胃液,聚维酮碘溶液(聚维酮碘50g/L)200—300ml喷洒灌洗,维持5min后,留取灌洗液5ml(标本B);经胃NOTES进行腹腔内手术操作后,留取腹腔抽取物5ml(标本C)。标本分别送检细菌培养及鉴定。术后置人胃管胃肠减压,抗炎、抑酸及补液支持处理,观察患者术后反应。结果所有患者均完成经胃内镜腹腔内手术,5例有不同程度的腹腔镜辅助。标本A2例培养阴性,7例阳性,细菌以肠道细菌为主;菌落计数平均为35.6×10^3CFU/ml。标本B和标本C细菌培养9例均为阴性。大部分患者术后无畏寒发热、恶心呕吐、明显腹胀腹痛等不适;术后血生化检查未见异常。术后1周复查胃镜,胃肠壁均无炎症、溃疡、出血等并发症,胃肠道切口止血夹闭合可,未见明显的渗漏等。所有患者术后随访6个月,均未出现感染等手术并发症。结论临床使用聚维酮碘溶液灌洗胃腔预防经胃NOTES感染是安全可行和有效的,当然,进一步临床研究评估其安全性有效性仍是必需的。 展开更多
关键词 感染 经自然腔道内镜手术 聚维酮碘 经胃路径 临床方案
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聚维酮碘溶液灌洗胃肠道预防经自然腔道内镜手术感染的实验研究 被引量:7
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作者 郑永志 王东 +3 位作者 顾俊骏 龚燕芳 吴仁培 李兆申 《中华消化内镜杂志》 北大核心 2011年第5期256-259,共4页
目的评价聚维酮碘溶液灌洗胃肠道在经自然腔道内镜手术(NOTES)的感染预防中的可行性和有效性。方法采用12只雌性家猪模型。对照组4只仅用生理盐水500ml灌洗胃肠道;实验组8只先用生理盐水500ml灌洗胃肠道,再用聚维酮碘溶液200ml灌洗... 目的评价聚维酮碘溶液灌洗胃肠道在经自然腔道内镜手术(NOTES)的感染预防中的可行性和有效性。方法采用12只雌性家猪模型。对照组4只仅用生理盐水500ml灌洗胃肠道;实验组8只先用生理盐水500ml灌洗胃肠道,再用聚维酮碘溶液200ml灌洗胃肠道。对照组及实验组均在经胃或结肠途径时先留取胃肠道液5ml,在生理盐水或聚维酮碘溶液灌洗后再留取灌洗液5ml,最后在NOTES完成后留取腹腔抽取物5ml,标本分别送检进行细菌培养及鉴定。术后24h复查内镜观察胃肠道有无炎症、溃疡、出血等。术后3周处死并解剖动物,观察腹腔内有无粘连、脓肿等感染情况。结果除实验组1例出现膈肌损伤死亡外,11例成功存活至3周后处死解剖。经胃途径的灌洗前细菌负荷平均为17.5×10^3CFU/ml,对照组生理盐水灌洗后平均为2.5×10^3CFU/ml,术后平均为5.5×10^3CFU/ml;实验组聚维酮碘灌洗后细菌负荷平均为0CFU/ml,术后平均为7.5CFU/ml。经结肠途径的灌洗前细菌负荷平均为76.2×10^3CFU/ml,对照组生理盐水灌洗后平均为19.5×10^3CFU/ml,术后平均为21×10^3CFU/ml;实验组聚维酮碘灌洗后细菌负荷平均为2.25×10^3CFU/ml,术后平均为1×10^3CFU/ml。术后24h复查内镜胃肠道均未见炎症、溃疡、出血等。3周后处死动物解剖发现对照组粘连、脓肿等多于实验组;实验组中仅有经结肠途径1例出现粘连。结论使用聚维酮碘溶液灌洗胃肠道预防NOTES感染是可行和有效的,但还需进一步临床研究评估其安全性有效性。 展开更多
关键词 经自然腔道内镜手术 家猪 经胃路径 经结肠路径 聚维酮碘 实验研究
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