目的观察瑞芬太尼复合丙泊酚靶控输注在腹腔镜胆囊切除术中的麻醉效果.方法将腹腔镜胆囊切除术患者280例随机分为瑞芬太尼复合丙泊酚靶控输注组(TCI组)和异氟烷复合丙泊酚组(对照组)各140例.比较两组各时间节点血流动力学参数的变化、...目的观察瑞芬太尼复合丙泊酚靶控输注在腹腔镜胆囊切除术中的麻醉效果.方法将腹腔镜胆囊切除术患者280例随机分为瑞芬太尼复合丙泊酚靶控输注组(TCI组)和异氟烷复合丙泊酚组(对照组)各140例.比较两组各时间节点血流动力学参数的变化、术毕不同时间节点的苏醒情况和镇静评分.结果与对照组比较,TCI组T1时间节点的SBP、DBP、HR差异有统计学意义(P<0.05);TCI组麻醉恢复的自主呼吸恢复时间、苏醒时间、拔管时间,差异有统计学意义(P<0.01);TCI组的5 min、10 min OAAS评分差异有统计学意义(P<0.01),但30 min后,两组差异无统计学意义(P>0.05).结论瑞芬太尼复合丙泊酚靶控输注麻醉,在麻醉诱导插管时易导致血压下降、心率减慢、术中血流动力学平稳;术毕苏醒迅速、完全,麻醉安全性高、可控性强.展开更多
团队创新氛围是创新研究与团队研究的一个结合点,在国内相关研究尚显薄弱。本文追踪国外的相关成果,运用了目前最被认可的TCI问卷(The Team Climate Inventory),对我国21个研发团队的142个样本进行测量。分析发现在我国TCI同样具有良好...团队创新氛围是创新研究与团队研究的一个结合点,在国内相关研究尚显薄弱。本文追踪国外的相关成果,运用了目前最被认可的TCI问卷(The Team Climate Inventory),对我国21个研发团队的142个样本进行测量。分析发现在我国TCI同样具有良好的内部一致性,而且团队创新氛围的各维度存在区别度;但团队创新氛围结构与国外研究略有差异;并且,影响基础研究团队与技术开发团队创新绩效的团队创新氛围有所不同。本研究将有助于我国研发团队的创新研究,对研发团队的管理理论和实践有一定启示。展开更多
Objective To study the effect of gender and ages on predict blood and effect-site EC50 for propofol and remifentanil TCI and bispectral index at loss of consciousness and response to a standard noxious painful stimulu...Objective To study the effect of gender and ages on predict blood and effect-site EC50 for propofol and remifentanil TCI and bispectral index at loss of consciousness and response to a standard noxious painful stimulus. Methods 405 ASA Ⅰ-Ⅱunpremedicated Chinese patients in 5 medical centers for elective operation were involved. Patients were allocated to 4 groups according to ages (group1: 18<age<30, group2: 30≤age<40, group3: 40≤age<50, group4: 50≤age<65). The propofol was started a predict blood concentration of 1.2 mg/L delivered by Diprifusor, and increased by 0.3 mg/L every 30 s until patients lost their consciousness. After that, effect-site concentration of propofol kept constant and infused remifentanil a predict blood concentration of 2.0 μg/L and increased by 0.3 μg/L every 30 s until they lost response to a standard noxious stimulus. Bispectral index was measured. Probit regression was used to estimate population values for predicted blood and effect-site propofol and remifentanil concentrations at the two clinical end-points and BIS. Results The effect-site and the predict blood propofol concentrations EC50 of male and female were similar. The predict blood and effect-site propofol concentrations EC50 of younger were higher than that of older and BIS values were lower. The blood and effect-site remifentanil ancentrations EC50 at no response to painful stimulus of male and female were similar. The blood and effect-site remifentanil concentrations EC50 and BIS values at this point of each group were similar. 50% of male and female patients lost their consciousness at a BIS value with 54.0 and 59.0 respectively; and at loss of response to painful stimulus with 60.8 and 67.3 respectively. Conclusion Gender didn’t affect the predicted propofol and remifentanil blood and effect-site concentration but affected the BIS values. The propofol concentrations of older were lower than that of younger. And that of remifentanil were not different between younger and older.展开更多
文摘目的观察瑞芬太尼复合丙泊酚靶控输注在腹腔镜胆囊切除术中的麻醉效果.方法将腹腔镜胆囊切除术患者280例随机分为瑞芬太尼复合丙泊酚靶控输注组(TCI组)和异氟烷复合丙泊酚组(对照组)各140例.比较两组各时间节点血流动力学参数的变化、术毕不同时间节点的苏醒情况和镇静评分.结果与对照组比较,TCI组T1时间节点的SBP、DBP、HR差异有统计学意义(P<0.05);TCI组麻醉恢复的自主呼吸恢复时间、苏醒时间、拔管时间,差异有统计学意义(P<0.01);TCI组的5 min、10 min OAAS评分差异有统计学意义(P<0.01),但30 min后,两组差异无统计学意义(P>0.05).结论瑞芬太尼复合丙泊酚靶控输注麻醉,在麻醉诱导插管时易导致血压下降、心率减慢、术中血流动力学平稳;术毕苏醒迅速、完全,麻醉安全性高、可控性强.
文摘团队创新氛围是创新研究与团队研究的一个结合点,在国内相关研究尚显薄弱。本文追踪国外的相关成果,运用了目前最被认可的TCI问卷(The Team Climate Inventory),对我国21个研发团队的142个样本进行测量。分析发现在我国TCI同样具有良好的内部一致性,而且团队创新氛围的各维度存在区别度;但团队创新氛围结构与国外研究略有差异;并且,影响基础研究团队与技术开发团队创新绩效的团队创新氛围有所不同。本研究将有助于我国研发团队的创新研究,对研发团队的管理理论和实践有一定启示。
文摘Objective To study the effect of gender and ages on predict blood and effect-site EC50 for propofol and remifentanil TCI and bispectral index at loss of consciousness and response to a standard noxious painful stimulus. Methods 405 ASA Ⅰ-Ⅱunpremedicated Chinese patients in 5 medical centers for elective operation were involved. Patients were allocated to 4 groups according to ages (group1: 18<age<30, group2: 30≤age<40, group3: 40≤age<50, group4: 50≤age<65). The propofol was started a predict blood concentration of 1.2 mg/L delivered by Diprifusor, and increased by 0.3 mg/L every 30 s until patients lost their consciousness. After that, effect-site concentration of propofol kept constant and infused remifentanil a predict blood concentration of 2.0 μg/L and increased by 0.3 μg/L every 30 s until they lost response to a standard noxious stimulus. Bispectral index was measured. Probit regression was used to estimate population values for predicted blood and effect-site propofol and remifentanil concentrations at the two clinical end-points and BIS. Results The effect-site and the predict blood propofol concentrations EC50 of male and female were similar. The predict blood and effect-site propofol concentrations EC50 of younger were higher than that of older and BIS values were lower. The blood and effect-site remifentanil ancentrations EC50 at no response to painful stimulus of male and female were similar. The blood and effect-site remifentanil concentrations EC50 and BIS values at this point of each group were similar. 50% of male and female patients lost their consciousness at a BIS value with 54.0 and 59.0 respectively; and at loss of response to painful stimulus with 60.8 and 67.3 respectively. Conclusion Gender didn’t affect the predicted propofol and remifentanil blood and effect-site concentration but affected the BIS values. The propofol concentrations of older were lower than that of younger. And that of remifentanil were not different between younger and older.
