2-Isoxazolines and 2-pyrazolines have been derived from oxime and hydrazone derivatives reacted with <i><i><span style="font-family:Verdana;">N</span></i></i><span styl...2-Isoxazolines and 2-pyrazolines have been derived from oxime and hydrazone derivatives reacted with <i><i><span style="font-family:Verdana;">N</span></i></i><span style="font-family:Verdana;">-chlorosuccinimide (NCS) and trichloroisocyanuric acid (TCCA). Cyclization strategy is developed for the reaction of <i></i></span><i><i><span style="font-family:Verdana;">β</span></i></i><span><span style="font-family:Verdana;">, <i></i></span><i><i><span style="font-family:Verdana;">γ</span></i></i></span><span style="font-family:Verdana;">-unsaturated hydrazones with the TCCA to drive 2-pyrazolines and the reaction of <i></i></span><i><i><span style="font-family:Verdana;">β</span></i></i><span><span style="font-family:Verdana;">, <i></i></span><i><i><span style="font-family:Verdana;">γ</span></i></i></span><span style="font-family:Verdana;">-unsaturated oximes with NCS to derive 2-isoxalzolines. Structures of all new 2-isoxazolines and 2-pyrazolines have been elucidated by microanalyses, <sup></sup></span><sup><span style="font-family:Verdana;">1</span></sup><span style="font-family:Verdana;">H, <sup></sup></span><sup><span style="font-family:Verdana;">13</span></sup><span style="font-family:Verdana;">C NMR and Mass spectroscopies.</span>展开更多
The crystal structure of 1-（2,6-dichloro-4-nitrophenyl）-5-amino-4-cyanopyrazole （C10H10Cl2N5O2, Mr = 298.09） has been determined by single-crystal X-ray diffraction. It crystallizes in the triclinic system, space ...The crystal structure of 1-（2,6-dichloro-4-nitrophenyl）-5-amino-4-cyanopyrazole （C10H10Cl2N5O2, Mr = 298.09） has been determined by single-crystal X-ray diffraction. It crystallizes in the triclinic system, space group P1^- with a = 8.1258（10）, b = 8.6460（10）, c = 10.0214（12） A, α = 68.986（2）, β = 71.598（2）, γ = 85.181（2）°, V = 623.26（13） A3, Z = 2, Dc = 1.588 g/cm^3,μ = 0.525 mm^-1, F（000） = 300, R = 0.0613 and wR = 0.1524 for 1890 observed reflections, and the extinction coefficient = 0.010（5）. The crystal structure is stabilized by N-H...N hydrogen bonds.展开更多
文摘2-Isoxazolines and 2-pyrazolines have been derived from oxime and hydrazone derivatives reacted with <i><i><span style="font-family:Verdana;">N</span></i></i><span style="font-family:Verdana;">-chlorosuccinimide (NCS) and trichloroisocyanuric acid (TCCA). Cyclization strategy is developed for the reaction of <i></i></span><i><i><span style="font-family:Verdana;">β</span></i></i><span><span style="font-family:Verdana;">, <i></i></span><i><i><span style="font-family:Verdana;">γ</span></i></i></span><span style="font-family:Verdana;">-unsaturated hydrazones with the TCCA to drive 2-pyrazolines and the reaction of <i></i></span><i><i><span style="font-family:Verdana;">β</span></i></i><span><span style="font-family:Verdana;">, <i></i></span><i><i><span style="font-family:Verdana;">γ</span></i></i></span><span style="font-family:Verdana;">-unsaturated oximes with NCS to derive 2-isoxalzolines. Structures of all new 2-isoxazolines and 2-pyrazolines have been elucidated by microanalyses, <sup></sup></span><sup><span style="font-family:Verdana;">1</span></sup><span style="font-family:Verdana;">H, <sup></sup></span><sup><span style="font-family:Verdana;">13</span></sup><span style="font-family:Verdana;">C NMR and Mass spectroscopies.</span>
基金the Natural Science Foundation of Zhejiang Province (No. Y404039)
文摘The crystal structure of 1-（2,6-dichloro-4-nitrophenyl）-5-amino-4-cyanopyrazole （C10H10Cl2N5O2, Mr = 298.09） has been determined by single-crystal X-ray diffraction. It crystallizes in the triclinic system, space group P1^- with a = 8.1258（10）, b = 8.6460（10）, c = 10.0214（12） A, α = 68.986（2）, β = 71.598（2）, γ = 85.181（2）°, V = 623.26（13） A3, Z = 2, Dc = 1.588 g/cm^3,μ = 0.525 mm^-1, F（000） = 300, R = 0.0613 and wR = 0.1524 for 1890 observed reflections, and the extinction coefficient = 0.010（5）. The crystal structure is stabilized by N-H...N hydrogen bonds.
