Redox state constitutes an important background of numerous liver disorders. The redox state participates in the course of inflammatory, metabolic and proliferative liver diseases. Reactive oxygen species(ROS) are pri...Redox state constitutes an important background of numerous liver disorders. The redox state participates in the course of inflammatory, metabolic and proliferative liver diseases. Reactive oxygen species(ROS) are primarily produced in the mitochondria and in the endoplasmic reticulum of hepatocytes via the cytochrome P450 enzymes. Under the proper conditions, cells are equipped with special molecular strategies that control the level of oxidative stress and maintain a balance between oxidant and antioxidant particles. Oxidative stress represents an imbalance between oxidant and antioxidant agents. Hepatocytic proteins, lipids and DNA are among the cellular structures that are primarily affected by ROS and reactive nitrogen species. The process results in structural and functional abnormalities in the liver. Thus, the phenomenon of oxidative stress should be investigated for several reasons. First, it may explain the pathogenesis of various liver disorders. Moreover, monitoring oxidative markers among hepatocytes offers the potential to diagnose the degree of liver damage and ultimately to observe the response to pharmacological therapies. The present report focuses on the role of oxidative stress in selected liver diseases.展开更多
This investigation report mainly displays a new public space of property management with the characteristics of civil society, by analyzing a typical case--Qing Shui Yuan. The new public space has already separated fr...This investigation report mainly displays a new public space of property management with the characteristics of civil society, by analyzing a typical case--Qing Shui Yuan. The new public space has already separated from the state and is managed by both the state and the society together. Position-exceeding power of the state and deficient position-stimulated rights of the society result in the tension between the state and the society. Position-exceeding power is a pivotal perspective to interpret the relation between the state and the society.Instead of paying excessive attention to the institutional construction of civil rights, we should focus on how social rights stimulated by institutions and laws are turned into reality.展开更多
The extended state observer (ESO) is a novel observer for a class of uncertain systems. Since ESO adopts the continuous non-smooth structure, the classical observer design theory is hard to use for ESO analysis. In th...The extended state observer (ESO) is a novel observer for a class of uncertain systems. Since ESO adopts the continuous non-smooth structure, the classical observer design theory is hard to use for ESO analysis. In this note, the self-stable region (SSR) approach, which is a nonlinear synthesis method for nonlinear uncertain systems, will be used for ESO design and its stability analysis. The advantages of the non-smooth structure in ESO for improving the convergence properties and the estimation precision will be shown.展开更多
Governance is a kind of holistic governance and the notion of governing holistically should be established. The holisticity of governance is reflected in the unity and coordination between value rationality and instru...Governance is a kind of holistic governance and the notion of governing holistically should be established. The holisticity of governance is reflected in the unity and coordination between value rationality and instrumental rationality, normative appeal and practical appeal as well as global governance and state governance. Global and state governances are two strategic considerations in contemporary China. Actively participating in global governance and rationally promoting state governance is the rational choice of contemporary China, which plays a unique and significant role in realizing the social transformation and national rejuvenation and modernization of contemporary China. Deepening state governance with the help of global governance and promoting global governance with the support of state governance is the basic idea and dimension of understanding and grasping the interaction, coordination and overall planning between the two. The restrictions and effects of global governance on state governance are mainly reflected in such considerations as objects, mechanisms, concepts and interests of governance, and modernization of state governance system and improvement of governance capacity can promote and deepen global governance in a more effective way.展开更多
In current Chinese rural areas there are no civil societies organized yet, but public spaces do exist. In the recent couple of decades, the public spaces in rural regions are developing with diversity, tea houses bein...In current Chinese rural areas there are no civil societies organized yet, but public spaces do exist. In the recent couple of decades, the public spaces in rural regions are developing with diversity, tea houses being the most active. In the middle and southern parts of Province Jiangxi, increased leisure time, coupled with changed views about leisure, has led to the custom of spending time at tea houses by rural residents, and a collective lifestyle of new consumer groups. Lively tea houses function not only as a “world of familiar folks” but also as a “world of freedom” for the farmers, having promoted the integration and stability at the grass-roots level. The operating rule of bottom-level society is embedded in these developing public spaces which are a convenient window for observing farmers’ social psychological drama and changes in rural societal structures. The rise and decline of public spaces such as tea houses are an outstanding manifestation and a result as well, of social changes in rural areas.展开更多
Integrated energy distribution system(IEDS)is one of the integrated energy and power system forms,which involves electricity/gas/cold/heat and other various energy forms.The energy coupling relationship is close and c...Integrated energy distribution system(IEDS)is one of the integrated energy and power system forms,which involves electricity/gas/cold/heat and other various energy forms.The energy coupling relationship is close and complex.IEDS is the focus of regional energy internet research and development at home and abroad.Compared with the traditional power distribution system,IEDS through the multi-energy coupling link comprehensive utilization,effectively improve the distribution system economy,safety,reliability,flexibility and toughness,but also to ease the regional energy system environmental pressure.IEDS is an important direction for the future development of energy systems,and its related research and practice on China’s energy system development also has important practical and strategic significance.This paper summarizes the related researches of the IEDS and explores the energy operation characteristics and coupling mechanisms.What’s more,the integrated model of IEDS is summarized.On these bases,this paper discusses and prospects some key issues such as joint planning,optimization control and security analysis,state estimation and situational awareness and generalized demand side management.展开更多
文摘Redox state constitutes an important background of numerous liver disorders. The redox state participates in the course of inflammatory, metabolic and proliferative liver diseases. Reactive oxygen species(ROS) are primarily produced in the mitochondria and in the endoplasmic reticulum of hepatocytes via the cytochrome P450 enzymes. Under the proper conditions, cells are equipped with special molecular strategies that control the level of oxidative stress and maintain a balance between oxidant and antioxidant particles. Oxidative stress represents an imbalance between oxidant and antioxidant agents. Hepatocytic proteins, lipids and DNA are among the cellular structures that are primarily affected by ROS and reactive nitrogen species. The process results in structural and functional abnormalities in the liver. Thus, the phenomenon of oxidative stress should be investigated for several reasons. First, it may explain the pathogenesis of various liver disorders. Moreover, monitoring oxidative markers among hepatocytes offers the potential to diagnose the degree of liver damage and ultimately to observe the response to pharmacological therapies. The present report focuses on the role of oxidative stress in selected liver diseases.
文摘This investigation report mainly displays a new public space of property management with the characteristics of civil society, by analyzing a typical case--Qing Shui Yuan. The new public space has already separated from the state and is managed by both the state and the society together. Position-exceeding power of the state and deficient position-stimulated rights of the society result in the tension between the state and the society. Position-exceeding power is a pivotal perspective to interpret the relation between the state and the society.Instead of paying excessive attention to the institutional construction of civil rights, we should focus on how social rights stimulated by institutions and laws are turned into reality.
文摘The extended state observer (ESO) is a novel observer for a class of uncertain systems. Since ESO adopts the continuous non-smooth structure, the classical observer design theory is hard to use for ESO analysis. In this note, the self-stable region (SSR) approach, which is a nonlinear synthesis method for nonlinear uncertain systems, will be used for ESO design and its stability analysis. The advantages of the non-smooth structure in ESO for improving the convergence properties and the estimation precision will be shown.
文摘Governance is a kind of holistic governance and the notion of governing holistically should be established. The holisticity of governance is reflected in the unity and coordination between value rationality and instrumental rationality, normative appeal and practical appeal as well as global governance and state governance. Global and state governances are two strategic considerations in contemporary China. Actively participating in global governance and rationally promoting state governance is the rational choice of contemporary China, which plays a unique and significant role in realizing the social transformation and national rejuvenation and modernization of contemporary China. Deepening state governance with the help of global governance and promoting global governance with the support of state governance is the basic idea and dimension of understanding and grasping the interaction, coordination and overall planning between the two. The restrictions and effects of global governance on state governance are mainly reflected in such considerations as objects, mechanisms, concepts and interests of governance, and modernization of state governance system and improvement of governance capacity can promote and deepen global governance in a more effective way.
文摘In current Chinese rural areas there are no civil societies organized yet, but public spaces do exist. In the recent couple of decades, the public spaces in rural regions are developing with diversity, tea houses being the most active. In the middle and southern parts of Province Jiangxi, increased leisure time, coupled with changed views about leisure, has led to the custom of spending time at tea houses by rural residents, and a collective lifestyle of new consumer groups. Lively tea houses function not only as a “world of familiar folks” but also as a “world of freedom” for the farmers, having promoted the integration and stability at the grass-roots level. The operating rule of bottom-level society is embedded in these developing public spaces which are a convenient window for observing farmers’ social psychological drama and changes in rural societal structures. The rise and decline of public spaces such as tea houses are an outstanding manifestation and a result as well, of social changes in rural areas.
基金This work was supported by the National High Technology Research and Development Program(863 Program)of China(2015AA050403)Natural Science Foundation of Tianjin(17JCQNJC06600)+2 种基金Independent Innovation Foundation of Tianjin University(Research on Key Technology of Distributed Demand Response)Ocean Engineering Equipment and Technical Think Tank Joint Project of Qingdao(201707071003)the Distributed Energy and Microgrid Project conducted in collaboration with APPLIED ENERGY UNiLAB-DEM.
文摘Integrated energy distribution system(IEDS)is one of the integrated energy and power system forms,which involves electricity/gas/cold/heat and other various energy forms.The energy coupling relationship is close and complex.IEDS is the focus of regional energy internet research and development at home and abroad.Compared with the traditional power distribution system,IEDS through the multi-energy coupling link comprehensive utilization,effectively improve the distribution system economy,safety,reliability,flexibility and toughness,but also to ease the regional energy system environmental pressure.IEDS is an important direction for the future development of energy systems,and its related research and practice on China’s energy system development also has important practical and strategic significance.This paper summarizes the related researches of the IEDS and explores the energy operation characteristics and coupling mechanisms.What’s more,the integrated model of IEDS is summarized.On these bases,this paper discusses and prospects some key issues such as joint planning,optimization control and security analysis,state estimation and situational awareness and generalized demand side management.