The Coronaviridae family is characterized by a nucleocapsid that is composed of the genome RNA molecule in combination with the nucleoprotein (N protein) within a virion. The most striking physiochemical feature of th...The Coronaviridae family is characterized by a nucleocapsid that is composed of the genome RNA molecule in combination with the nucleoprotein (N protein) within a virion. The most striking physiochemical feature of the N protein of SARS-CoV is that it is a typical basic protein with a high predicted pI and high hydrophilicity, which is consistent with its function of binding to the ribophosphate backbone of the RNA molecule. The predicted high extent of phosphorylation of the N protein on multiple candidate phosphorylation sites demonstrates that it would be related to important functions, such as RNA-binding and localization to the nucleolus of host cells. Subsequent study shows that there is an SR-rich region in the N protein and this region might be involved in the protein-protein interaction. The abundant antigenic sites predicted in the N protein, as well as experimental evidence with synthesized polypeptides, indicate that the N protein is one of the major antigens of the SARS-CoV. Compared with other viral structural proteins, the low variation rate of the N protein with regards to its size suggests its importance to the survival of the virus.展开更多
The mountain rocks in the Dushan Complex are Sr-rich granite with a much higher Sr level than those in other crustal lithospheres in eastern China. That presents a high potential for developing Sr-rich mineral water. ...The mountain rocks in the Dushan Complex are Sr-rich granite with a much higher Sr level than those in other crustal lithospheres in eastern China. That presents a high potential for developing Sr-rich mineral water. In this study, 6 groups of rock samples, together with 30 groups of water samples, were collected. Combining with the existing data, the Sr contents in three different types of underground water were obtained, which are the Quaternary pore water, the meshed bedrock fissure water in weathered zones and the tectonic bedrock fissure water. On the basis of preliminary understanding for the distribution characteristics of Sr-rich mineral water in the Dushan Mountain region, the causes for the Sr-rich mineral water were investigated. Our results showed that the Sr content of the rocks in the studied area ranges from 988 to 1 950 μg/g. In the horizontal direction, those in both the pore water and the meshed bedrock fissure water in weathered zones show high values in the west but low ones in the east, and high ones in the south but low ones in the north. Furthermore, both types of water meet the standard for Sr-rich mineral water in the western areas. In the vertical direction, the Sr content shows the lowest value in pore water(the average value is 0.707 mg/L), middle value in the meshed bedrock fissure water in weathered zones(the average value is 1.415 mg/L) and the highest value in the tectonic bedrock fissure water(the average value is 8.331 mg/L). It was thought that the widely-developed Sr-rich granite in this region provides physical sources for the formation of Sr-rich mineral water. The continuous dissolution of Sr during underground water runoff is the internal mechanism. In addition, the hydraulic interrelations may exist between the three vertical aquifers, leading a continuous accumulation of the Sr level during infiltration.展开更多
Abundant apatite grains with elevated SrO content were found in leucitite-ijolite xenoliths in the Dangzi Mountain,Heilongjiang Province.Morphological and mineralogical associations,and compositional analysis of the S...Abundant apatite grains with elevated SrO content were found in leucitite-ijolite xenoliths in the Dangzi Mountain,Heilongjiang Province.Morphological and mineralogical associations,and compositional analysis of the Sr-rich apatite,were carried out using an electron microprobe.Two principal types of apatite were distinguished.One type occurs as short-prismatic crystals with Sr-rich rims,while another type with acicular or finely columnar shapes constitutes Sr-rich apatite element maps and systematic quantitative analysis of apatite revealed great variations in SrO content (0.42%-26.79%).The calculated structural formula of the measured Sr-rich apatite is:(Ca3.15-4.963Sr0.019-1.510Ba0.00-0.030Na0.006-0.108REE0.106-0.153) (P2.84-3.028Si0.009-0.094)O12(F0.675-1.079,Cl0.000-0.256,OH0.084-0.297).Mineralogical textures of apatite implied a replacement mechanism for the Sr-rich apatite.Sr-rich rims of apatite are suggested to have formed after metasomatism (isomorphic replacement) of early fluorapatite in a Sr-,light rare-earth elements (LREE),lithophile light elements (LILE)-and volatile-rich residual melt during late magmatism.However,the acicular apatite probably directly crystallized from a Sr-rich residual melt.The Sr-Nd isotopic composition of the apatite was distinctive from that of leucitite-ijolite and its host rock.These differences,combined with mineralogical features of apatite,imply that Sr-LREE-LILE-volatile-rich components in the residual melt were derived from deep in the asthenosphere,and subsequently were enriched at a late stage in magma evolution.展开更多
Strontium has four naturally occurring stable isotopes,84Sr,86Sr,87Sr,and 88Sr,with abundances of 0.56,9.87,approximately 7.04,and 82.53 atomic %,respectively.The 87Sr/86Sr isotope ratio is variable due to the additio...Strontium has four naturally occurring stable isotopes,84Sr,86Sr,87Sr,and 88Sr,with abundances of 0.56,9.87,approximately 7.04,and 82.53 atomic %,respectively.The 87Sr/86Sr isotope ratio is variable due to the addition of radiogenic 87Sr produced by the beta decay of 87Rb with a half-life of 4.88 ± 0.05 Ga.Thus,展开更多
Objective The Jiaodong area in Shandong Province of eastern China hosts abundant high-quality groundwater. Most of the mineral water sources in this area, including those in the Laoshan and Kunyu Mountains, occur in ...Objective The Jiaodong area in Shandong Province of eastern China hosts abundant high-quality groundwater. Most of the mineral water sources in this area, including those in the Laoshan and Kunyu Mountains, occur in Mesozoic granites. The groundwater and mineral waters contain metasilicic acid and strontium but the latter is potable. Mineral water is also found in the Jiaolai Basin, hosting in the basalts of the Wangshi group in Anjiagou Village, Jiaozhou City. The rapeutic groundwater, however, is rarely found in this area, except for the recent discovery of CO：-Li-Sr rich therapeutic and potable groundwater, which is reported in this study.展开更多
文摘The Coronaviridae family is characterized by a nucleocapsid that is composed of the genome RNA molecule in combination with the nucleoprotein (N protein) within a virion. The most striking physiochemical feature of the N protein of SARS-CoV is that it is a typical basic protein with a high predicted pI and high hydrophilicity, which is consistent with its function of binding to the ribophosphate backbone of the RNA molecule. The predicted high extent of phosphorylation of the N protein on multiple candidate phosphorylation sites demonstrates that it would be related to important functions, such as RNA-binding and localization to the nucleolus of host cells. Subsequent study shows that there is an SR-rich region in the N protein and this region might be involved in the protein-protein interaction. The abundant antigenic sites predicted in the N protein, as well as experimental evidence with synthesized polypeptides, indicate that the N protein is one of the major antigens of the SARS-CoV. Compared with other viral structural proteins, the low variation rate of the N protein with regards to its size suggests its importance to the survival of the virus.
基金financially supported by scientific research project of Hebei Geological and Mineral Resource Bureau(454-0601-YBN-VKK1)
文摘The mountain rocks in the Dushan Complex are Sr-rich granite with a much higher Sr level than those in other crustal lithospheres in eastern China. That presents a high potential for developing Sr-rich mineral water. In this study, 6 groups of rock samples, together with 30 groups of water samples, were collected. Combining with the existing data, the Sr contents in three different types of underground water were obtained, which are the Quaternary pore water, the meshed bedrock fissure water in weathered zones and the tectonic bedrock fissure water. On the basis of preliminary understanding for the distribution characteristics of Sr-rich mineral water in the Dushan Mountain region, the causes for the Sr-rich mineral water were investigated. Our results showed that the Sr content of the rocks in the studied area ranges from 988 to 1 950 μg/g. In the horizontal direction, those in both the pore water and the meshed bedrock fissure water in weathered zones show high values in the west but low ones in the east, and high ones in the south but low ones in the north. Furthermore, both types of water meet the standard for Sr-rich mineral water in the western areas. In the vertical direction, the Sr content shows the lowest value in pore water(the average value is 0.707 mg/L), middle value in the meshed bedrock fissure water in weathered zones(the average value is 1.415 mg/L) and the highest value in the tectonic bedrock fissure water(the average value is 8.331 mg/L). It was thought that the widely-developed Sr-rich granite in this region provides physical sources for the formation of Sr-rich mineral water. The continuous dissolution of Sr during underground water runoff is the internal mechanism. In addition, the hydraulic interrelations may exist between the three vertical aquifers, leading a continuous accumulation of the Sr level during infiltration.
基金supported by the National Natural Science Foundation of China (40672039,41372103 and 40221301)
文摘Abundant apatite grains with elevated SrO content were found in leucitite-ijolite xenoliths in the Dangzi Mountain,Heilongjiang Province.Morphological and mineralogical associations,and compositional analysis of the Sr-rich apatite,were carried out using an electron microprobe.Two principal types of apatite were distinguished.One type occurs as short-prismatic crystals with Sr-rich rims,while another type with acicular or finely columnar shapes constitutes Sr-rich apatite element maps and systematic quantitative analysis of apatite revealed great variations in SrO content (0.42%-26.79%).The calculated structural formula of the measured Sr-rich apatite is:(Ca3.15-4.963Sr0.019-1.510Ba0.00-0.030Na0.006-0.108REE0.106-0.153) (P2.84-3.028Si0.009-0.094)O12(F0.675-1.079,Cl0.000-0.256,OH0.084-0.297).Mineralogical textures of apatite implied a replacement mechanism for the Sr-rich apatite.Sr-rich rims of apatite are suggested to have formed after metasomatism (isomorphic replacement) of early fluorapatite in a Sr-,light rare-earth elements (LREE),lithophile light elements (LILE)-and volatile-rich residual melt during late magmatism.However,the acicular apatite probably directly crystallized from a Sr-rich residual melt.The Sr-Nd isotopic composition of the apatite was distinctive from that of leucitite-ijolite and its host rock.These differences,combined with mineralogical features of apatite,imply that Sr-LREE-LILE-volatile-rich components in the residual melt were derived from deep in the asthenosphere,and subsequently were enriched at a late stage in magma evolution.
文摘Strontium has four naturally occurring stable isotopes,84Sr,86Sr,87Sr,and 88Sr,with abundances of 0.56,9.87,approximately 7.04,and 82.53 atomic %,respectively.The 87Sr/86Sr isotope ratio is variable due to the addition of radiogenic 87Sr produced by the beta decay of 87Rb with a half-life of 4.88 ± 0.05 Ga.Thus,
基金funded by the key R&D program of Shandong Province“Deep Gold Resources Evaluation Theories,Methodologies and Prognoses”(grant No.2017CXGC1604)the“Special Project Fund of Taishan Scholars of Shandong Province”(grant No.ts201511076)
文摘Objective The Jiaodong area in Shandong Province of eastern China hosts abundant high-quality groundwater. Most of the mineral water sources in this area, including those in the Laoshan and Kunyu Mountains, occur in Mesozoic granites. The groundwater and mineral waters contain metasilicic acid and strontium but the latter is potable. Mineral water is also found in the Jiaolai Basin, hosting in the basalts of the Wangshi group in Anjiagou Village, Jiaozhou City. The rapeutic groundwater, however, is rarely found in this area, except for the recent discovery of CO：-Li-Sr rich therapeutic and potable groundwater, which is reported in this study.
