Due to the chemoselective dehalogenation by SmI2, the addition of α-halomethylsulfones to carbonyl compounds afforded β-hy-droxysulfones. Those reactions with α-bromomethylsulfones gave the products in moderate to ...Due to the chemoselective dehalogenation by SmI2, the addition of α-halomethylsulfones to carbonyl compounds afforded β-hy-droxysulfones. Those reactions with α-bromomethylsulfones gave the products in moderate to good yields. The SmI2-mediat-ed addition of gem-dihalomethylsulfones to ketones also afforded α-halo-β-hydroxysulfones in moderate yields.展开更多
基金Project supported by the National Natural Science Foundation of China(No.20272050).
文摘Due to the chemoselective dehalogenation by SmI2, the addition of α-halomethylsulfones to carbonyl compounds afforded β-hy-droxysulfones. Those reactions with α-bromomethylsulfones gave the products in moderate to good yields. The SmI2-mediat-ed addition of gem-dihalomethylsulfones to ketones also afforded α-halo-β-hydroxysulfones in moderate yields.
