Background： Arterial grafts had better mid-term and long-term patency than saphenous vein grafts in coronary artery bypass grafting （CABG）. We summarized our experience with total arterial off-pump coronary artery ...Background： Arterial grafts had better mid-term and long-term patency than saphenous vein grafts in coronary artery bypass grafting （CABG）. We summarized our experience with total arterial off-pump coronary artery bypass grafting （OPCAB） and assessed the early clinical results, surgical complications, and follow-up. Methods： From January 2007 to May 2017,508 coronary artery disease patients undergoing total arterial OPCAB were enrolled. Clinical features, approaches, outcomes of surgical treatments, and follow-up data of these patients were studied retrospectively. A total of 122 patients underwent single left internal mammary artery （IMA）-left anterior descending artery grafts, whereas the other 386 patients underwent multiple vessel grafts. Results： The average distal anastomosis was 2.34 ± 0.97 （range： 1-4）. All the patients were discharged from hospital except one died. A total of 457 （90.32%） patients were followed up. In the 4-, 7-, and 10-year follow-up groups, the rate of death from any cause was 1.19%, 6.47%, and 10.67%; rate of cardiac death was 0.60%, 2.88%, and 3.33%; rate of repeat revascularization was 0.00%, 3.60%. and 8.67%; rate ofischemic symptoms was 1.79%, 7.91%, and 11.33%; and incidence of stroke was 2.38%, 4.32%, and 6.67%, respectively. Poor medication adherence was observed in 9.38% of the follow-up population. Conclusions： Total arterial OPCAB with bilateral IMA, radial artery, and right gastroepiploic artery grafting yielded satisfactory early and midterm outcomes in this patient group, without a significant increase in early mortality or morbidity. Moreover, the long-term outcomes are also positive.展开更多
目的总结骨骼化游离乳内动脉应用于冠状动脉旁路移植术的近中期结果及初步体会。方法回顾性分析2014年1月-2015年10月在解放军总医院心血管外科采用骨骼化游离技术获取乳内动脉行冠状动脉旁路移植术的56例患者的临床资料,其中男46例,女1...目的总结骨骼化游离乳内动脉应用于冠状动脉旁路移植术的近中期结果及初步体会。方法回顾性分析2014年1月-2015年10月在解放军总医院心血管外科采用骨骼化游离技术获取乳内动脉行冠状动脉旁路移植术的56例患者的临床资料,其中男46例,女10例,年龄61.8±7.7岁。收集患者人口学资料、主要合并症、围术期相关指标以及术后早期结果。全组患者术后常规随访,记录主要不良事件发生情况。结果 56例患者共获取乳内动脉59支,其中左乳内动脉55支,右乳内动脉4支,3例患者取双侧乳内动脉,取动脉时间为55.5±13.0min。根据获取顺序将全组患者分为组1（前29例）和组2（后27例）,两组均成功获取乳内动脉,两组桥血流量（30.4±14.4ml/min vs 30.3±16.0ml/min）比较差异无统计学意义（P=0.986）,但组1取动脉时间（60.7±14.4min）明显长于组2（50.0±8.4min）,差异有统计学意义（P=0.001）。56例患者远端吻合口数为2.96±0.89个,无30d死亡、围术期心肌梗死、再次开胸止血及切口感染或愈合不良等严重并发症。所有患者术后随访1～23个月,无心肌梗死及再次再血管化,1例患者于术后3个月死于急性肺动脉栓塞。结论骨骼化游离乳内动脉应用于冠状动脉旁路移植术安全可行,近中期结果满意。展开更多
Summary： Phrenic nerve injury after cardiac surgery increases postoperative pulmonary complications. The purpose of this study was to analyze the causes and effects of phrenic nerve injury after cardiac surgery. Pros...Summary： Phrenic nerve injury after cardiac surgery increases postoperative pulmonary complications. The purpose of this study was to analyze the causes and effects of phrenic nerve injury after cardiac surgery. Prospectively collected data on 2084 consecutive patients who underwent cardiac surgery from Jan. 1995 to Feb. 2002 were analyzed. Twenty-eight preoperative and operation related variables were subjected to logistic analysis with the end point being phrenic nerve injury. Then phrenic nerve injury and 6 perioperative morbidities were included in the analysis as variables to determine their independent predictive value for perioperative pulmonary morbidity. An identical approach was used to identify the independent risk factors for perioperative mortality. There were 53 phrenic nerve injuries （2.5 %）. There was no phrenic nerve injury in non-coronary surgery or coronary surgery using conduits other than the internal mammary artery. The independent risk factors for phrenic nerve injury were the use of internal mammary artery （Odds ratio （OR）=14.5） and the presence of chronic obstructive pulmonary disease （OR=2.9）. Phrenic nerve injury was an independent risk factor （OR=8.1） for perioperative pulmonary morbidities but not for perioperative mortality. Use of semi-skeletonized internal mammary artery harvesting technique and drawing attention to possible vascular or mechanical causes of phrenic nerve injury may reduce its occurrence. Unilateral phrenic nerve injury, although rarely life-threatening, is an independent risk factor for postoperative respiratory complications. When harvesting internal mammary arteries, it should be kept in mind avoiding stretching, compromising, or inadvertently dissecting phrenic nerve is as important as avoiding damage of internal mammary artery itself.展开更多
基金This study was funded by a grant from the National Natural Science Foundation of China （No. 81370237）.
文摘Background： Arterial grafts had better mid-term and long-term patency than saphenous vein grafts in coronary artery bypass grafting （CABG）. We summarized our experience with total arterial off-pump coronary artery bypass grafting （OPCAB） and assessed the early clinical results, surgical complications, and follow-up. Methods： From January 2007 to May 2017,508 coronary artery disease patients undergoing total arterial OPCAB were enrolled. Clinical features, approaches, outcomes of surgical treatments, and follow-up data of these patients were studied retrospectively. A total of 122 patients underwent single left internal mammary artery （IMA）-left anterior descending artery grafts, whereas the other 386 patients underwent multiple vessel grafts. Results： The average distal anastomosis was 2.34 ± 0.97 （range： 1-4）. All the patients were discharged from hospital except one died. A total of 457 （90.32%） patients were followed up. In the 4-, 7-, and 10-year follow-up groups, the rate of death from any cause was 1.19%, 6.47%, and 10.67%; rate of cardiac death was 0.60%, 2.88%, and 3.33%; rate of repeat revascularization was 0.00%, 3.60%. and 8.67%; rate ofischemic symptoms was 1.79%, 7.91%, and 11.33%; and incidence of stroke was 2.38%, 4.32%, and 6.67%, respectively. Poor medication adherence was observed in 9.38% of the follow-up population. Conclusions： Total arterial OPCAB with bilateral IMA, radial artery, and right gastroepiploic artery grafting yielded satisfactory early and midterm outcomes in this patient group, without a significant increase in early mortality or morbidity. Moreover, the long-term outcomes are also positive.
文摘目的总结骨骼化游离乳内动脉应用于冠状动脉旁路移植术的近中期结果及初步体会。方法回顾性分析2014年1月-2015年10月在解放军总医院心血管外科采用骨骼化游离技术获取乳内动脉行冠状动脉旁路移植术的56例患者的临床资料,其中男46例,女10例,年龄61.8±7.7岁。收集患者人口学资料、主要合并症、围术期相关指标以及术后早期结果。全组患者术后常规随访,记录主要不良事件发生情况。结果 56例患者共获取乳内动脉59支,其中左乳内动脉55支,右乳内动脉4支,3例患者取双侧乳内动脉,取动脉时间为55.5±13.0min。根据获取顺序将全组患者分为组1（前29例）和组2（后27例）,两组均成功获取乳内动脉,两组桥血流量（30.4±14.4ml/min vs 30.3±16.0ml/min）比较差异无统计学意义（P=0.986）,但组1取动脉时间（60.7±14.4min）明显长于组2（50.0±8.4min）,差异有统计学意义（P=0.001）。56例患者远端吻合口数为2.96±0.89个,无30d死亡、围术期心肌梗死、再次开胸止血及切口感染或愈合不良等严重并发症。所有患者术后随访1～23个月,无心肌梗死及再次再血管化,1例患者于术后3个月死于急性肺动脉栓塞。结论骨骼化游离乳内动脉应用于冠状动脉旁路移植术安全可行,近中期结果满意。
基金This project was supported by a grant from the Shanxi Pro-vincial Foundation (No.74-2003)
文摘Summary： Phrenic nerve injury after cardiac surgery increases postoperative pulmonary complications. The purpose of this study was to analyze the causes and effects of phrenic nerve injury after cardiac surgery. Prospectively collected data on 2084 consecutive patients who underwent cardiac surgery from Jan. 1995 to Feb. 2002 were analyzed. Twenty-eight preoperative and operation related variables were subjected to logistic analysis with the end point being phrenic nerve injury. Then phrenic nerve injury and 6 perioperative morbidities were included in the analysis as variables to determine their independent predictive value for perioperative pulmonary morbidity. An identical approach was used to identify the independent risk factors for perioperative mortality. There were 53 phrenic nerve injuries （2.5 %）. There was no phrenic nerve injury in non-coronary surgery or coronary surgery using conduits other than the internal mammary artery. The independent risk factors for phrenic nerve injury were the use of internal mammary artery （Odds ratio （OR）=14.5） and the presence of chronic obstructive pulmonary disease （OR=2.9）. Phrenic nerve injury was an independent risk factor （OR=8.1） for perioperative pulmonary morbidities but not for perioperative mortality. Use of semi-skeletonized internal mammary artery harvesting technique and drawing attention to possible vascular or mechanical causes of phrenic nerve injury may reduce its occurrence. Unilateral phrenic nerve injury, although rarely life-threatening, is an independent risk factor for postoperative respiratory complications. When harvesting internal mammary arteries, it should be kept in mind avoiding stretching, compromising, or inadvertently dissecting phrenic nerve is as important as avoiding damage of internal mammary artery itself.
