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分娩镇痛的临床应用与管理 被引量:90
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作者 刘兴会 吴连方 《中华妇产科杂志》 CAS CSCD 北大核心 2005年第6期362-364,共3页
关键词 分娩镇痛 临床应用 simpson 管理 妇产科医生 分娩期保健 分娩疼痛 产痛
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引产方式及时机对妊娠期糖尿病患者妊娠结局的影响 被引量:17
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作者 谢玲娟 张雅丽 赵晶 《中国妇幼健康研究》 2020年第3期382-386,共5页
目的探讨不同引产方式及时机对妊娠期糖尿病患者妊娠结局的影响及安全性。方法回顾性分析2016年6月至2018年12月期间在陕西省宝鸡市妇幼保健院妇产科分娩的188例妊娠期糖尿病患者,按不同的引产时机分为A组(n=64,38~39^+6周)、B组(n=68,4... 目的探讨不同引产方式及时机对妊娠期糖尿病患者妊娠结局的影响及安全性。方法回顾性分析2016年6月至2018年12月期间在陕西省宝鸡市妇幼保健院妇产科分娩的188例妊娠期糖尿病患者,按不同的引产时机分为A组(n=64,38~39^+6周)、B组(n=68,40~40^+6周)和C组(n=56,41~41^+6周),按不同的引产方式分为人工破膜+缩宫素引产(n=125)和欣普贝生引产(n=63)。观察所有产妇的妊娠结局,并对产妇及新生儿的状况进行1个月的追踪随访。结果A组剖宫产率(31.25%)显著高于C组(7.14%),差异有统计学意义(χ^2=10.848,P<0.05),C组羊水过少显著高于A组,差异有统计学意义(χ^2=8.496,P<0.05),三组子痫前期、胎膜早破、产后出血量、产褥病、总产程比较,差异均无统计学意义(P>0.05)。C组巨大儿(28.57%)、胎儿宫内窘迫(25.00%)、新生儿窒息(12.50%)均显著高于A组,差异有统计学意义(χ^2=12.147、15.214、8.496,均P<0.05)。两种引产方式阴道分娩率、产后出血、总产程、剖宫产指征、新生儿随访期间并发症比较,差异均无统计学意义(均P>0.05)。结论对于妊娠期糖尿病孕妇,应做好孕期血糖控制,完善孕期管理,不应单纯根据孕周决定引产时机,应根据宫颈成熟程度及胎儿情况等适时选择引产时机和引产方式,有助于提高引产成功率并降低母婴并发症的发生率。 展开更多
关键词 妊娠期糖尿病 欣普贝生 缩宫素 引产 妊娠结局
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药物经济学评价中Markov模型的周期内校正方法探讨 被引量:9
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作者 沃田 陈磊 席晓宇 《中国药房》 CAS 北大核心 2020年第8期980-984,共5页
目的:为减少药物经济学研究中Markov模型的误差提供参考。方法:参考国外相关文献,解释Markov模型误差产生的原理,并介绍常用的半周期法、梯形法、Simpson’s 1/3法、Simpson’s 3/8法、生命表法及其在Excel、TreeAge软件中的实现方法。... 目的:为减少药物经济学研究中Markov模型的误差提供参考。方法:参考国外相关文献,解释Markov模型误差产生的原理,并介绍常用的半周期法、梯形法、Simpson’s 1/3法、Simpson’s 3/8法、生命表法及其在Excel、TreeAge软件中的实现方法。结果与结论:Markov模型因离散化过程而产生误差,使用周期内校正方法可校正这一误差。半周期法是最常用的校正方法,是通过增加第1周期一半的结果并减去最后1周期一半的结果进行校正;梯形法的校正是以区间首尾端点值的均值代表该区间,以直角梯形的面积作为累计的结果;Simpson’s 1/3法和Simpson’s 3/8法则在梯形法的基础上在区间中插值并以插值点所在的连续曲线代表整个曲线;寿命表法的校正中,生存人年数为该年龄组的组距与该年龄组和下一年龄组尚存人数的均值的乘积,生存人年数则为各年龄组生存总人年数的总和。在Excel中,可根据方法原理设置函数来实现校正;而在TreeAge软件中,可通过设置Init Rwd、Incr Rwd、Final Rwd的函数表达式来实现校正。在使用Markov模型进行药物经济学评价时,对于周期校正方法的选择,若从建模的易用性、适用情形的广泛性等角度出发,建议使用梯形法;从结果的精确性角度出发,则建议使用Simpson’s 1/3法,以提高Markov模型的准确度。 展开更多
关键词 药物经济学 MARKOV模型 周期内校正 半周期法 梯形法 simpson’s 1/3法 simpson’s 3/8法 寿命表法
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产科麻醉及分娩镇痛大有可为 被引量:12
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作者 姚尚龙 伍静 《中华麻醉学杂志》 CAS CSCD 北大核心 2016年第11期1293-1294,共2页
产科麻醉及分娩镇痛的历史可以追溯到现代麻醉学的开端。早在1846年WilianThomasMorton首次成功公开演示乙醚麻醉完成下颌肿瘤切除术之前,英国的妇产科医生JamesYoungSimpson于1842年至1846年期间即采用乙醚麻醉来缓解分娩疼痛。1847年... 产科麻醉及分娩镇痛的历史可以追溯到现代麻醉学的开端。早在1846年WilianThomasMorton首次成功公开演示乙醚麻醉完成下颌肿瘤切除术之前,英国的妇产科医生JamesYoungSimpson于1842年至1846年期间即采用乙醚麻醉来缓解分娩疼痛。1847年,Simpson医生又尝试采用氯仿进行分娩镇痛。最经典的病例莫过于他在1853年为当时的Victoria女皇采用氯仿麻醉实施分娩镇痛, 展开更多
关键词 分娩镇痛 产科麻醉 simpson 妇产科医生 乙醚麻醉 现代麻醉学 肿瘤切除术 分娩疼痛
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68例睾丸扭转患者的临床诊治分析 被引量:10
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作者 王逸民 姜海 +3 位作者 李方印 陈昭典 朱选文 蔡松良 《中华急诊医学杂志》 CAS CSCD 2007年第5期538-540,共3页
睾丸扭转又称精索扭转,是阴囊急症的常见原因之一,近年来对本病的认识虽有所提高,但仍存在较高误诊率。据Corbett和Simpson统计,急诊医师和泌尿外科专家能早期正确诊断该病的概率分别为39%和76%,因此睾丸扭转仍是年轻男性失去睾... 睾丸扭转又称精索扭转,是阴囊急症的常见原因之一,近年来对本病的认识虽有所提高,但仍存在较高误诊率。据Corbett和Simpson统计,急诊医师和泌尿外科专家能早期正确诊断该病的概率分别为39%和76%,因此睾丸扭转仍是年轻男性失去睾丸的常见原因。本院1992年1月至2005年4月问共收治68例睾丸扭转患者,现报道如下。 展开更多
关键词 睾丸扭转 诊治分析 simpson 临床 精索扭转 阴囊急症 外科专家 急诊医师
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Soil Parameter Identification for Wheel-terrain Interaction Dynamics and Traversability Prediction 被引量:8
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作者 Suksun Hutangkabodee Yahya Hashem Zweiri +1 位作者 Lakmal Dasarath Seneviratne Kaspar Althoefer 《International Journal of Automation and computing》 EI 2006年第3期244-251,共8页
This paper presents a novel technique for identifying soil parameters for a wheeled vehicle traversing unknown terrain. The identified soil parameters are required for predicting vehicle drawbar pull and wheel drive t... This paper presents a novel technique for identifying soil parameters for a wheeled vehicle traversing unknown terrain. The identified soil parameters are required for predicting vehicle drawbar pull and wheel drive torque, which in turn can be used for traversability prediction, traction control, and performance optimization of a wheeled vehicle on unknown terrain. The proposed technique is based on the Newton Raphson method. An approximated form of a wheel-soil interaction model based on Composite Simpson's Rule is employed for this purpose. The key soil parameters to be identified are internal friction angle, shear deformation modulus, and lumped pressure-sinkage coefficient. The fourth parameter, cohesion, is not too relevant to vehicle drawbar pull, and is assigned an average value during the identification process. Identified parameters are compared with known values, and shown to be in agreement. The identification method is relatively fast and robust. The identified soil parameters can effectively be used to predict drawbar pull and wheel drive torque with good accuracy. The use of identified soil parameters to design a traversability criterion for wheeled vehicles traversing unknown terrain is presented. 展开更多
关键词 Soil parameter traversability Newton Raphson Composite simpson's Rule wheeled vehicle
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嗅沟脑膜瘤全切除后颅底重建 被引量:8
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作者 刘玉光 刘猛 +3 位作者 陈昱 李峰 朱树干 吴承远 《中华外科杂志》 CAS CSCD 北大核心 2007年第2期129-130,共2页
嗅沟脑膜瘤是最常见前颅底肿瘤,占颅内脑膜瘤的2%~18%。由于对侧嗅觉的代偿或肿瘤生长缓慢,早期症状不明显,以至发现肿瘤时已生长巨大并侵蚀颅底骨质,约15%~46%的嗅沟脑膜瘤侵蚀颅骨进入筛窦。Durante于1885年首次切除嗅沟脑... 嗅沟脑膜瘤是最常见前颅底肿瘤,占颅内脑膜瘤的2%~18%。由于对侧嗅觉的代偿或肿瘤生长缓慢,早期症状不明显,以至发现肿瘤时已生长巨大并侵蚀颅底骨质,约15%~46%的嗅沟脑膜瘤侵蚀颅骨进入筛窦。Durante于1885年首次切除嗅沟脑膜瘤,术后患者存活12年。现代显微技术使嗅沟脑膜瘤全切除率几乎达到100%,死亡率降至0~2%,术后并发症发生率平均7.5%。我科1996年7月至2004年12月收治嗅沟脑膜病36例(占我院同期颅内脑膜瘤3.8%)其中17例颅底骨质受到侵蚀,按Simpson Ⅰ切除肿瘤后行颅底重建,效果良好,现报告如下。 展开更多
关键词 嗅沟脑膜瘤 颅底重建 切除后 前颅底肿瘤 simpson 颅内脑膜瘤 并发症发生率 生长缓慢
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实时三维超声心动图测量心肌梗死后室壁运动异常患者左室收缩功能的研究 被引量:9
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作者 刘丽萍 殷霞 +2 位作者 陈建成 张月玲 李志华 《山西医药杂志》 CAS 2018年第7期772-773,共2页
随着我国人民生活水平的提高和社会压力的增大,冠心病的发病率日益增高,而且呈现年轻化趋势,给家庭和社会造成极大的经济损失。一直以来心肌梗死患者的左室收缩功能测定都是一个难题,尤其对于出现明显室壁运动异常的患者,M型法及二维Sim... 随着我国人民生活水平的提高和社会压力的增大,冠心病的发病率日益增高,而且呈现年轻化趋势,给家庭和社会造成极大的经济损失。一直以来心肌梗死患者的左室收缩功能测定都是一个难题,尤其对于出现明显室壁运动异常的患者,M型法及二维Simpson′s法都不能准确测量患者左室整体收缩功能。而新近发展起来的实时三维超声心动图,由于其不基于几何图形的假设,可以客观实时地显示心脏的立体结构和动态变化、并可以显示心脏异常病变与正常结构的毗邻位置及空间关系,因此能够提供更为丰富的诊断信息,而且操作简单、方便快捷。本研究就是应用这种方法测量左室心肌梗死后节段性室壁运动异常患者的左室整体收缩功能,旨在为此类患者提供更好的诊断及治疗依据。 展开更多
关键词 节段性室壁运动异常 实时三维超声心动图 心肌梗死患者 左室收缩功能 测量 死后 左室整体收缩功能 simpson
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Effects of Bacterial-Feeding Nematode Grazing and Tea Saponin Addition on the Enhanced Bioremediation of Pyrene-Contaminated Soil Using Polycyclic Aromatic Hydrocarbon-Degrading Bacterial Strain 被引量:7
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作者 SUN Mingming LIU Kuan +5 位作者 ZHAO Yuanchao TIAN Da YE Mao LIU Manqiang JIAO Jiaguo JIANG Xin 《Pedosphere》 SCIE CAS CSCD 2017年第6期1062-1072,共11页
As one of the most widely distributed bacterial predators in the soil, the role of bacterivorous nematodes on the enhanced bioremediation of polycyclic aromatic hydrocarbon-contaminated soils is crucial, but remains t... As one of the most widely distributed bacterial predators in the soil, the role of bacterivorous nematodes on the enhanced bioremediation of polycyclic aromatic hydrocarbon-contaminated soils is crucial, but remains to be investigated.A microcosm-level study was conducted to examine the effects of bacterial-feeding nematode grazing and tea saponin(TS) addition on bioremediation of a pyrene-contaminated soil enhanced by the polycyclic aromatic hydrocarbon(PAH)-degrading bacterial strain Sphingobium sp.PHE9.After 180 d of incubation, the highest pyrene dissipation(71.3%) was achieved through a combination of Sphingobium sp.PHE9 inoculation with nematode and TS addition.Meanwhile, high counts of culturable PAH-degrading bacteria, soil enzyme activity, and biodiversity indices were observed under the combined treatment, implying that the microbiological function of the contaminated soil was significantly restored.Additionally, the results of Tenax~ extraction with the first-order three-compartment model indicated that rate-limiting factors varied among treatments.The lack of degrading microorganisms was the main rate-limiting factor for the treatments involving TS/nematode addition, and inadequate bioaccessible pyrene was the vital rate-limiting factor in the treatments involving Sphingobium sp.PHE9 inoculation.The proposed combined clean-up strategy proved to be a promising bioremediation technology for aged pyrene-contaminated soils. 展开更多
关键词 desorbing fraction desorption rate constant physiological profile of soil microbial community Shannon-Weaver index simpson index soil microbial activity Sphingobium sp.PHE9
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Glypican-3 as a specific biomarker for hepatocellular carcinoma 被引量:6
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作者 Min Yao Liu-Hong Pan Deng-Fu Yao 《Hepatobiliary & Pancreatic Diseases International》 SCIE CAS CSCD 2015年第2期122-123,共2页
Glypican(GPC)is a family of heparan sulfate proteoglycans bounded to the cell surface through a lipid glycosyl-phosphatidylinositol anchor.GPC-3 that its gene located at Xq26.1 area on chromosome,is one of the six m... Glypican(GPC)is a family of heparan sulfate proteoglycans bounded to the cell surface through a lipid glycosyl-phosphatidylinositol anchor.GPC-3 that its gene located at Xq26.1 area on chromosome,is one of the six mammalian glypicans(GPC-1 to GPC-6),causes the Simpson-Golabi-Behmel overgrowth syndrome,and displays developmental overgrowth in null mice.[1]GPC-3 promotes cell proliferation by stimulating canonical Wnt signaling,and acts as an inhibitor 展开更多
关键词 heparan simpson chromosome biomarker anchor developmental stimulating canonical hepatoma extrahepatic
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经典SIMPSON求积公式的新证明 被引量:6
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作者 石艳霞 刘证 《数学的实践与认识》 CSCD 北大核心 2005年第6期245-247,共3页
对于定积分近似计算中常使用的经典SIMPSON求积公式介绍一种新的简洁的证明方法并给出误差的最佳估计.
关键词 定积分 simpson 求积公式 误差估计 分部积分法
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Supersonic Two-Dimensional Minimum Length Nozzle Design at High Temperature. Application for Air 被引量:5
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作者 Toufik Zebbiche ZineEddine Youbi 《Chinese Journal of Aeronautics》 SCIE EI CAS CSCD 2007年第1期29-39,共11页
When the stagnation temperature of a perfect gas increases, the specific heat ratio does not remain constant any more, and start to vary with this temperature. The gas remains perfect, its state equation remains alway... When the stagnation temperature of a perfect gas increases, the specific heat ratio does not remain constant any more, and start to vary with this temperature. The gas remains perfect, its state equation remains always valid, except it will name in more calorically imperfect gas or gas at High Temperature. The goal of this work is to trace the profiles of the supersonic Minimum Length Nozzle with centered expansion when the stagnation temperature is taken into account, lower than the threshold of dissociation of the molecules and to have for each exit Mach number several nozzles shapes by changing the value of the temperature. The method of characteristics is used with a new form of the Prandtl Meyer function at high temperature. The resolution of the obtained equations is done by the second order of fmite differences method by using the predictor corrector algorithm. A study on the error given by the perfect gas model compared to our model is presented. The comparison is made with a calorically perfect gas for goal to give a limit of application of this model. The application is for the air. 展开更多
关键词 supersonic flow minimum length nozzle calorically imperfect gas interpolation Prandtl Meyer function stretching function simpson quadrature supersonic parameters conception method of characteristics
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紫金山城市森林鸟类群落结构特征研究
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作者 孙洁梅 张哲海 +5 位作者 闻欣 赵广华 皮亚洲 章翔 王芬 郑建 《环境生态学》 2024年第8期46-48,137,共4页
通过研究城市森林鸟类生物多样性,可以很好地了解鸟类与环境之间的相互关系,为城市绿地建设和修复所借鉴。2022年8月—2023年4月,采用样线法对紫金山城市森林公园的鸟类多样性进行观测。共记录到鸟类78种(11目28科),雀形目的鸟类占据着... 通过研究城市森林鸟类生物多样性,可以很好地了解鸟类与环境之间的相互关系,为城市绿地建设和修复所借鉴。2022年8月—2023年4月,采用样线法对紫金山城市森林公园的鸟类多样性进行观测。共记录到鸟类78种(11目28科),雀形目的鸟类占据着主导地位(80.72%),留鸟为主(70.5%)。从季节变化看,鸟类香农-维纳指数变化范围2.95~3.27,优势度指数变化范围0.879~0.949,均匀度指数变化范围0.744~0.865。冬季与春季的相似性系数最高,共有种有35种。紫金山城市森林公园鸟种数季节变化总体不大。 展开更多
关键词 城市森林 鸟类多样性 雀形目 居留型 香农-维纳指数 优势度指数 均匀度指数
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Ostrowski’s Type Inequalities for Generalized(h,m)−Preinvex Functions with Its Applications
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作者 LI Ran LIAN Tie-yan 《Chinese Quarterly Journal of Mathematics》 2024年第3期270-287,共18页
A new concept generalized(h,m)−preinvex function on Yang’s fractal sets is proposed.Some Ostrowski’s type inequalities with two parameters for generalized(h,m)−preinvex function are established,where three local fra... A new concept generalized(h,m)−preinvex function on Yang’s fractal sets is proposed.Some Ostrowski’s type inequalities with two parameters for generalized(h,m)−preinvex function are established,where three local fractional inequalities involving generalized midpoint type,trapezoid type and Simpson type are derived as consequences.Furthermore,as some applications,special means inequalities and numerical quadratures for local fractional integrals are discussed. 展开更多
关键词 Generalized(h m)−preinvex function Hermite−Hadamard inequality Ostrowski inequality simpson inequality
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Occurrence of dark septate endophytes in Phragmites australis in the Baiyang Lake and their resistance to Cd stress
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作者 Minghui XU Xia LI +2 位作者 Qiannan YE Feng GONG Xueli HE 《Pedosphere》 SCIE CAS CSCD 2024年第2期484-496,共13页
Heavy metal pollution poses a serious hazard to human health,and microbial remediation of heavy metals in soil has been widely studied.A group of ascomycetes classified as dark septate endophytes(DSEs)colonize plant r... Heavy metal pollution poses a serious hazard to human health,and microbial remediation of heavy metals in soil has been widely studied.A group of ascomycetes classified as dark septate endophytes(DSEs)colonize plant roots and benefit host plants under abiotic stress conditions.In this study,Phragmites australis,a common remediation plant in the Baiyang Lake in North China,was investigated.Soils and roots of P.australis were collected in typical heavy metal-contaminated sites,and the species diversity and community structure of DSEs in P.australis roots were studied.In addition,DSE strains were isolated,cultured,and tested for their tolerance to Cd stress.The results showed that DSEs occurred extensively in P.australis roots,forming typical dark septate hyphae,with a total colonization rate of 19.7%–83.1%.Morphological and internal transcribed spacer sequencing analyses were used to identify 10 species within 9 genera of DSE fungi.Among these fungi,6 strains with considerable resistance to Cd stress were identified.The biomasses of Poaceascoma helicoides,Alternaria doliconidium,and Acrocalymma vagum strains increased as the Cd levels increased.These results can not only help to understand plant-DSE interactions in wetland environments,but also provide a theoretical basis for making full use of DSE fungi to alleviate heavy metal contamination in soil. 展开更多
关键词 ASCOMYCETE colonization rate contaminated site evenness index heavy metal Shannon-Wiener index simpson index WETLAND
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New indices to balanceα-diversity against tree size inequality
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作者 Li Zhang Brady K.Quinn +4 位作者 Cang Hui Meng Lian Johan Gielis Jie Gao Peijian Shi 《Journal of Forestry Research》 SCIE EI CAS CSCD 2024年第1期229-237,共9页
The number and composition of species in a community can be quantified withα-diversity indices,including species richness(R),Simpson’s index(D),and the Shannon-Wiener index(H΄).In forest communities,there are large ... The number and composition of species in a community can be quantified withα-diversity indices,including species richness(R),Simpson’s index(D),and the Shannon-Wiener index(H΄).In forest communities,there are large variations in tree size among species and individu-als of the same species,which result in differences in eco-logical processes and ecosystem functions.However,tree size inequality(TSI)has been largely neglected in studies using the available diversity indices.The TSI in the diameter at breast height(DBH)data for each of 99920 m×20 m forest census quadrats was quantified using the Gini index(GI),a measure of the inequality of size distribution.The generalized performance equation was used to describe the rotated and right-shifted Lorenz curve of the cumulative proportion of DBH and the cumulative proportion of number of trees per quadrat.We also examined the relationships ofα-diversity indices with the GI using correlation tests.The generalized performance equation effectively described the rotated and right-shifted Lorenz curve of DBH distributions,with most root-mean-square errors(990 out of 999 quadrats)being<0.0030.There were significant positive correlations between each of threeα-diversity indices(i.e.,R,D,and H’)and the GI.Nevertheless,the total abundance of trees in each quadrat did not significantly influence the GI.This means that the TSI increased with increasing spe-cies diversity.Thus,two new indices are proposed that can balanceα-diversity against the extent of TSI in the com-munity:(1−GI)×D,and(1−GI)×H’.These new indices were significantly correlated with the original D and H΄,and did not increase the extent of variation within each group of indices.This study presents a useful tool for quantifying both species diversity and the variation in tree sizes in forest communities,especially in the face of cumulative species loss under global climate change. 展开更多
关键词 Diameter at breast height(DBH) Gini index Shannon-Wiener index simpson’s index QUADRAT Tree size
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McCarthy法治疗新生儿先天性巨大左心室室壁瘤1例
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作者 高强 马良龙 +1 位作者 张泽伟 俞建根 《中华小儿外科杂志》 CSCD 北大核心 2024年第1期69-71,共3页
男,系其母首次怀孕剖宫产下的足月儿,出生体重3.04 kg。胎儿27周时发现左心室室壁瘤,且瘤体随胎龄逐渐增大。出生后不久出现心率一过性降至46~54次/min,经刺激后回升至100~130次/min。心脏超声检查提示射血分数(ejection fraction,EF)(M... 男,系其母首次怀孕剖宫产下的足月儿,出生体重3.04 kg。胎儿27周时发现左心室室壁瘤,且瘤体随胎龄逐渐增大。出生后不久出现心率一过性降至46~54次/min,经刺激后回升至100~130次/min。心脏超声检查提示射血分数(ejection fraction,EF)(M/2D法)39.4%,EF(Simpsons法)26.3%,予多巴胺5μg·kg^(-1)·min^(-1)维持下,在出生后15 h转至浙江大学医学院附属儿童医院。 展开更多
关键词 附属儿童医院 超声检查提示 左心室室壁瘤 射血分数 浙江大学医学院 出生体重 simpson 新生儿
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脑膜瘤瘤周硬膜组织蛋白酶D表达与肿瘤复发的关系 被引量:3
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作者 陈坚 刘汉东 陈刚 《中华神经外科疾病研究杂志》 CAS 2005年第5期419-422,共4页
目的对组织蛋白酶D(cathepsin D)在脑膜瘤及瘤周硬膜中的表达进行研究,并探讨其在Simpson I级切除脑膜瘤术后复发中的可能临床意义。方法临床上行Simpson I级切除的脑膜瘤51例,术中分别取标本肿瘤组织51例,瘤周肿瘤侵犯的硬膜组织(A组)4... 目的对组织蛋白酶D(cathepsin D)在脑膜瘤及瘤周硬膜中的表达进行研究,并探讨其在Simpson I级切除脑膜瘤术后复发中的可能临床意义。方法临床上行Simpson I级切除的脑膜瘤51例,术中分别取标本肿瘤组织51例,瘤周肿瘤侵犯的硬膜组织(A组)44例,瘤周术中肉眼/镜下认为正常的硬膜组织(B组)51例,距瘤缘至少大于6cm的正常硬膜组织(C组)15例。利用免疫组织化学方法检测各组标本的cathepsin D、增殖细胞核抗原(PCNA)表达。结果Cathepsin D在脑膜瘤组织中的表达与肿瘤的分级相关,在A组、B组、C组硬膜中的表达值分别为0.1366±0.0431、0.1149±0.0239、0.0789±0.0211,各组之间比较有显著性差异。Cathepsin D和PCNA的表达呈正相关。结论Cathepsin D可作为脑膜瘤复发的预测指标之一。脑膜瘤Simpson I级切除后瘤周肉眼/镜下认为正常的硬膜组织在分子蛋白水平已有肿瘤细胞的残存或浸润,是术后复发的原因之一,Simpson0级切除值得临床推荐。 展开更多
关键词 脑膜瘤 组织蛋白酶D simpson Ⅰ级 免疫组织化学
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Developing Skills in Intra-Workplace Rehabilitation Education: II
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作者 Fukumi Hiragami 《Open Journal of Gastroenterology》 2023年第3期98-121,共24页
This study aimed to develop an educational model that integrates three elements: knowledge, skills, and attitudes—developing the educational model proposed in the previous Paper I—and to widely investigate and chara... This study aimed to develop an educational model that integrates three elements: knowledge, skills, and attitudes—developing the educational model proposed in the previous Paper I—and to widely investigate and characterize previous learning-related models. The basic educational model proposed here is my seven-step process model of rehabilitation practice. Knowledge consists of four aspects: 1) clinical, 2) psychological, 3) environmental, and 4) disability;skills consist of two steps: 5) identifying intervention points and 6) setting feasible goals;and attitudes 7) of communicating and sharing policies and paths with patients, families, and other professionals. This constitutes the process of rehabilitation practice, and a framework that integrates the three elements is developed here. This study focuses on integrating knowledge, skills, and attitudes into what Bloom described as “the integration of instruction and assessment” so that learners and instructors can reconcile them. Therefore, a typology that explains each other for advancing and deepening individual skills is adopted. In Bloom’s original taxonomy of educational goals, the cognitive domain has five layers in the pyramid of knowledge;the psychomotor domain of Simpson’s has seven layers, and Bloom’s affective domain is represented by five in another pyramid. In addition, the above seven layers of the process model and the seven layers of the skill level of the Dreyfus model were brought together. The integration of the above five typologies becomes a useful educational evaluation model when the relationships are clarified. 展开更多
关键词 Japanese Rehabilitation Education Dreyfus Bloom and simpson’s Taxonomies Cruess’s Rehabilitation Skills The DOES EPA and DOPS
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Fuzzy Henstock-Kurzweil Triple Integral
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作者 Kumwimba Seya Didier Kasongo Ntambwe Dany +1 位作者 Mayuke Katshongo Jean-Paul Lunda Ngoie Jean-Pierre 《Journal of Applied Mathematics and Physics》 2023年第7期1860-1870,共11页
In this article, we use the Hausdorf distance to treat triple Simpson’s rule of the Henstock triple integral of a fuzzy valued function as well as the error bound of the method. We also introduce δ-fine subdivisions... In this article, we use the Hausdorf distance to treat triple Simpson’s rule of the Henstock triple integral of a fuzzy valued function as well as the error bound of the method. We also introduce δ-fine subdivisions for a Henstock triple integral and numerical example is presented in order to show the application and the consequence of the method. 展开更多
关键词 Fuzzy-Valued Function Hausdorff Distance Triple Fuzzy Integral Triple simpson’s Rule δ-Fine Henstock Integral
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