Objective: We investigated the correlations between background parenchymal enhancement (BPE) and MRI interpretations with respect to short-interval follow-ups and biopsy rates. Methods: All accessible MRI examinations...Objective: We investigated the correlations between background parenchymal enhancement (BPE) and MRI interpretations with respect to short-interval follow-ups and biopsy rates. Methods: All accessible MRI examinations from 128 women during a limited time period in 2016 were evaluated. A blinded radiologist visually categorized BPE as minimal, mild, moderate, or marked. A BI-RADS category was also assigned. We used descriptive statistics to report the findings and chi-square and Fisher’s exact tests to compare categories. Results: Prevalence of minimal, mild, moderate, and marked BPE was 14.1%, 43.0%, 32.0%, and 10.9%, respectively. The short-interval follow-up rates were 22.2%, 27.3%, 26.8%, and 7.1% in women with minimal, mild, moderate, and marked BPE, respectively. BPE was not associated with the short-interval follow-up rate (p-value = 0.477). Biopsy rates were 22.2%, 27.3%, 22.0%, and 57.1% in women with minimal, mild, moderate, and marked BPE, respectively. Although there was no significant relationship between biopsy rates and BPE levels (p-value = 0.095) in the total population, these two factors were significantly associated in premenopausal women (p-value = 0.023) and in women of 30 - 39 years (p-value = 0.001). Conclusion: Higher BPE does not correlate with short-interval follow-up rates, but appears to be related to biopsy rate, thus causing false-positives and unnecessary biopsy recommendations, particularly in younger, premenopausal women.展开更多
文摘Objective: We investigated the correlations between background parenchymal enhancement (BPE) and MRI interpretations with respect to short-interval follow-ups and biopsy rates. Methods: All accessible MRI examinations from 128 women during a limited time period in 2016 were evaluated. A blinded radiologist visually categorized BPE as minimal, mild, moderate, or marked. A BI-RADS category was also assigned. We used descriptive statistics to report the findings and chi-square and Fisher’s exact tests to compare categories. Results: Prevalence of minimal, mild, moderate, and marked BPE was 14.1%, 43.0%, 32.0%, and 10.9%, respectively. The short-interval follow-up rates were 22.2%, 27.3%, 26.8%, and 7.1% in women with minimal, mild, moderate, and marked BPE, respectively. BPE was not associated with the short-interval follow-up rate (p-value = 0.477). Biopsy rates were 22.2%, 27.3%, 22.0%, and 57.1% in women with minimal, mild, moderate, and marked BPE, respectively. Although there was no significant relationship between biopsy rates and BPE levels (p-value = 0.095) in the total population, these two factors were significantly associated in premenopausal women (p-value = 0.023) and in women of 30 - 39 years (p-value = 0.001). Conclusion: Higher BPE does not correlate with short-interval follow-up rates, but appears to be related to biopsy rate, thus causing false-positives and unnecessary biopsy recommendations, particularly in younger, premenopausal women.
文摘目的探讨女性孕期短PR间期的发生率、机制及与甲状腺激素水平的关系。方法采用今科心电信息网络系统工作站对40 301例健康体检者（其中女性未孕）及8 257例健康孕妇分别进行常规心电图检查,采用化学发光免疫测定法测定孕期游离三碘甲腺原氨酸（free three iodine thyroid original ammonia acid,FT3）,游离四碘甲腺原氨酸（free iodine thyroid original ammonia acid,FT4）,促甲状腺素（thyrotropin,TSH）。孕妇按孕周不同分孕早期（12周内）、孕中期（13～28周）和孕晚期（29周后）三组,分别进行PR间期及FT3、FT4、TSH的测定。结果健康体检者发生短PR间期120例（0.3%）,其中男41例（0.102%）,女79例（0.196%）;孕妇短PR间期111例（1.344%）,孕妇发生率明显增高,孕早中晚期的发生率两两比较,差异有统计学意义（P〈0.01）。FT3、FT4随孕周增加而降低,FT4在三组中两两比较,差异有统计学意义（P〈0.05）,TSH与孕周呈正相关,孕早中期比较差异无统计学意义（P〉0.05）,孕早中期与晚期比较差异有统计学意义（P〈0.05）。结论孕妇短PR间期发生率明显高于健康体检者,并与甲状腺激素水平有一定相关性。
