目的：研究特异性免疫治疗前后变应性鼻炎患者血清白细胞介素IL-6、IL-8、IL-12的变化及意义。方法：用酶联免疫吸附试验ELISA检测健康体检者（对照组）19名，变应性鼻炎（鼻炎组）70例特异性免疫治疗前后的血清IL-6、IL-8、IL...目的：研究特异性免疫治疗前后变应性鼻炎患者血清白细胞介素IL-6、IL-8、IL-12的变化及意义。方法：用酶联免疫吸附试验ELISA检测健康体检者（对照组）19名，变应性鼻炎（鼻炎组）70例特异性免疫治疗前后的血清IL-6、IL-8、IL-12及总免疫球蛋白ETIgE水平。结果：鼻炎组特异性免疫治疗前与对照组相比，IL-6、IL-8、IL-12均明显升高，P ＜0．01；特异性免疫治疗后与治疗前相比，IL-8显著降低 P ＜0．01，IL-6明显降低 P ＜0．05，IL-12虽有降低，但无显著性差异，P ＞0．05。特异性免疫治疗前IL-6、IL-8与TIgE呈正相关，IL-12与TIgE呈负相关。结论：特异性免疫治疗使变应性鼻炎患者IL-6、IL-8、IL-12的分泌趋于正常，提示特异性免疫治疗有可能通过改善机体的免疫功能而发挥作用。展开更多
Objective: The comparison of the remote and recent therapeutic effects on perennial allergic rhinitis was carried on among single application of acupoint-thread embedding, western medicine (certirizine+flixonase) and ...Objective: The comparison of the remote and recent therapeutic effects on perennial allergic rhinitis was carried on among single application of acupoint-thread embedding, western medicine (certirizine+flixonase) and allied therapy. Method: Ninety cases were randomized into thread-embedding group, western medicine group and embedding+western medicine group (allied-therapy group), 30 cases in each one. In thread embedding group, Yingxiang (迎香 LI 20) and Feishu (肺俞 BL 13) were selected for thread embedding, once a week, totally 4 treatments were required. In western medicine group, certirizine tablet 10 mg in combination with flixonase sprayer was applied once per day, continuously for 30 days in treatment. In allied-therapy group, both of the above methods were adopted continuously for 30 days in treatment. The therapeutic effects were in statistics at the end of treatment and 1 year later. Results: At the end of treatment, in thread-embedding group, 21 cases were remarkably effective, 3 cases effective and 6 cases no effect. In western medicine group, 20 cases were remarkably effective, 3 cases effective and 7 cases no effect. In allied-therapy group, 23 cases were remarkably effective, 2 cases effective and 5 cases no effect. It was shown in statistics that there was no significant difference in therapeutic effects among three groups ( P>0.05 ). But one year after the end of treatment, it was indicated that in thread-embedding group, 3 cases were remarkably effective, 10 cases effective and 17 cases no effect; in western medicine group, 2 cases were remarkably effective, 9 cases effective and 19 cases no effect; in allied-therapy group, 7 cases were remarkably effective, 11 cases effective and 12 cases no effect. The significant difference in the therapeutic effects had not been presented in the comparison between thread-embedding group and western medicine group (P>0.05), but that had been presented between allied-therapy group with either of the groups with single therapy applied (P<0.05). Conclusion: 展开更多
文摘目的：研究特异性免疫治疗前后变应性鼻炎患者血清白细胞介素IL-6、IL-8、IL-12的变化及意义。方法：用酶联免疫吸附试验ELISA检测健康体检者（对照组）19名，变应性鼻炎（鼻炎组）70例特异性免疫治疗前后的血清IL-6、IL-8、IL-12及总免疫球蛋白ETIgE水平。结果：鼻炎组特异性免疫治疗前与对照组相比，IL-6、IL-8、IL-12均明显升高，P ＜0．01；特异性免疫治疗后与治疗前相比，IL-8显著降低 P ＜0．01，IL-6明显降低 P ＜0．05，IL-12虽有降低，但无显著性差异，P ＞0．05。特异性免疫治疗前IL-6、IL-8与TIgE呈正相关，IL-12与TIgE呈负相关。结论：特异性免疫治疗使变应性鼻炎患者IL-6、IL-8、IL-12的分泌趋于正常，提示特异性免疫治疗有可能通过改善机体的免疫功能而发挥作用。
文摘Objective: The comparison of the remote and recent therapeutic effects on perennial allergic rhinitis was carried on among single application of acupoint-thread embedding, western medicine (certirizine+flixonase) and allied therapy. Method: Ninety cases were randomized into thread-embedding group, western medicine group and embedding+western medicine group (allied-therapy group), 30 cases in each one. In thread embedding group, Yingxiang (迎香 LI 20) and Feishu (肺俞 BL 13) were selected for thread embedding, once a week, totally 4 treatments were required. In western medicine group, certirizine tablet 10 mg in combination with flixonase sprayer was applied once per day, continuously for 30 days in treatment. In allied-therapy group, both of the above methods were adopted continuously for 30 days in treatment. The therapeutic effects were in statistics at the end of treatment and 1 year later. Results: At the end of treatment, in thread-embedding group, 21 cases were remarkably effective, 3 cases effective and 6 cases no effect. In western medicine group, 20 cases were remarkably effective, 3 cases effective and 7 cases no effect. In allied-therapy group, 23 cases were remarkably effective, 2 cases effective and 5 cases no effect. It was shown in statistics that there was no significant difference in therapeutic effects among three groups ( P>0.05 ). But one year after the end of treatment, it was indicated that in thread-embedding group, 3 cases were remarkably effective, 10 cases effective and 17 cases no effect; in western medicine group, 2 cases were remarkably effective, 9 cases effective and 19 cases no effect; in allied-therapy group, 7 cases were remarkably effective, 11 cases effective and 12 cases no effect. The significant difference in the therapeutic effects had not been presented in the comparison between thread-embedding group and western medicine group (P>0.05), but that had been presented between allied-therapy group with either of the groups with single therapy applied (P<0.05). Conclusion:
