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Rapid screening of SARS-CoV-2 inhibitors via ratiometric fluorescence of RBD–ACE2 complexes in living cells by competitive binding 被引量:1
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作者 Lu Miao Wei Zhou +14 位作者 Chunyu Yan Yuebin Zhang Qinglong Qiao Xuelian Zhou Yingzhu Chen Guangying Wang Zhendong Guo Jun Liu Hailong Piao Xia Pan Mengxue Yan Weijie Zhao Guohui Li Yueqing Li Zhaochao Xu 《Acta Pharmaceutica Sinica B》 SCIE CAS CSCD 2022年第9期3739-3742,共4页
To the Editor:The current coronavirus disease-19(COVID-19)pandemic spurs the development of antiviral drugs for SARS-CoV-2,as the number of patients with viral infections continues to rise globally in the context of w... To the Editor:The current coronavirus disease-19(COVID-19)pandemic spurs the development of antiviral drugs for SARS-CoV-2,as the number of patients with viral infections continues to rise globally in the context of widespread vaccination.Targeting the interaction between the receptor binding domain(RBD)of SARS-CoV-2 spike protein and the host cell ACE2 is a promising therapeutic strategy to effectively inhibit viral entry. 展开更多
关键词 SARS-CoV-2 rbdace2 interaction Inhibitors screening Live-cell imaging
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