目的:探讨巴布剂穴位贴敷对气滞血瘀型胸痹患者的临床疗效。方法:将60例气滞血瘀型胸痹患者随机分为研究组和对照组各30例,对照组进行西医基础治疗,研究组在西医基础治疗基础上,予以中药制成巴布剂进行穴位贴敷。并在患者出院后继续随访...目的:探讨巴布剂穴位贴敷对气滞血瘀型胸痹患者的临床疗效。方法:将60例气滞血瘀型胸痹患者随机分为研究组和对照组各30例,对照组进行西医基础治疗,研究组在西医基础治疗基础上,予以中药制成巴布剂进行穴位贴敷。并在患者出院后继续随访,进行跟踪观察与指导。结果:研究组总有效率优于对照组(P<0.05);治疗后两组间西雅图心绞痛量表评分比较,研究组躯体活动受限程度、治疗满意程度、疾病认知程度优于对照组(P<0.05),研究组心绞痛稳定情况、心绞痛发作情况优于对照组(P<0.01);研究组中医证候疗效优于对照组(P<0.05);治疗后两组间血脂变化情况比较,研究组甘油三酯(Triglycerides,TG)、总胆固醇(Total Cholesterol,CHOL)、高密度脂蛋白(High Density Lipoprotein,HDL)、低密度脂蛋白(Low Density Lipoprotein,LDL)优于对照组(P<0.05)。结论:巴布剂穴位贴敷能缓解气滞血瘀型胸痹患者的心绞痛症状,改善中医证候,降低TG、CHOL、LDL,升高HDL,减少心血管不良事件,提高患者的生活质量。展开更多
[Objectives] To establish the process flow of preparation of Wufang Babu Poultice and the identification method of thin layer chromatography (TLC). [Methods] For the forming process of Wufang Babu Poultice, the prepar...[Objectives] To establish the process flow of preparation of Wufang Babu Poultice and the identification method of thin layer chromatography (TLC). [Methods] For the forming process of Wufang Babu Poultice, the preparation method of mixed pharmaceutical powder with suitable pharmaceutical excipients was adopted. Qualitative identification of medicinal materials in Wufang Babu Poultice (Strychni Semen, Rhei Radix Et Rhizoma, Dipsaci Radix, and Angelicae Sinensis Radix) was carried out by TLC. [Results] Mixed pharmaceutical powder mixed with glycerol, gelatin and other pharmaceutical excipients can be prepared for forming. The test solution chromatography of each medicinal material (Strychni Semen, Rhei Radix et Rhizoma, Dipsaci Radix, Angelicae Sinensis Radix) showed pigment spots of the same color at the same position as its corresponding control medicinal materials and reference chromatography, and the display was clear. [Conclusions] The preparation process is simple and feasible, and can be used as the forming process of Wufang Babu Poultice. The TLC determination method is simple to operate, has good specificity, and has no effect on negative results, and can be used for identification of Wufang Babu Poultice.展开更多
文摘目的:探讨巴布剂穴位贴敷对气滞血瘀型胸痹患者的临床疗效。方法:将60例气滞血瘀型胸痹患者随机分为研究组和对照组各30例,对照组进行西医基础治疗,研究组在西医基础治疗基础上,予以中药制成巴布剂进行穴位贴敷。并在患者出院后继续随访,进行跟踪观察与指导。结果:研究组总有效率优于对照组(P<0.05);治疗后两组间西雅图心绞痛量表评分比较,研究组躯体活动受限程度、治疗满意程度、疾病认知程度优于对照组(P<0.05),研究组心绞痛稳定情况、心绞痛发作情况优于对照组(P<0.01);研究组中医证候疗效优于对照组(P<0.05);治疗后两组间血脂变化情况比较,研究组甘油三酯(Triglycerides,TG)、总胆固醇(Total Cholesterol,CHOL)、高密度脂蛋白(High Density Lipoprotein,HDL)、低密度脂蛋白(Low Density Lipoprotein,LDL)优于对照组(P<0.05)。结论:巴布剂穴位贴敷能缓解气滞血瘀型胸痹患者的心绞痛症状,改善中医证候,降低TG、CHOL、LDL,升高HDL,减少心血管不良事件,提高患者的生活质量。
基金Supported by Key R&D Plan of Guangxi Zhuang Autonomous Region(Guike AB20297010).
文摘[Objectives] To establish the process flow of preparation of Wufang Babu Poultice and the identification method of thin layer chromatography (TLC). [Methods] For the forming process of Wufang Babu Poultice, the preparation method of mixed pharmaceutical powder with suitable pharmaceutical excipients was adopted. Qualitative identification of medicinal materials in Wufang Babu Poultice (Strychni Semen, Rhei Radix Et Rhizoma, Dipsaci Radix, and Angelicae Sinensis Radix) was carried out by TLC. [Results] Mixed pharmaceutical powder mixed with glycerol, gelatin and other pharmaceutical excipients can be prepared for forming. The test solution chromatography of each medicinal material (Strychni Semen, Rhei Radix et Rhizoma, Dipsaci Radix, Angelicae Sinensis Radix) showed pigment spots of the same color at the same position as its corresponding control medicinal materials and reference chromatography, and the display was clear. [Conclusions] The preparation process is simple and feasible, and can be used as the forming process of Wufang Babu Poultice. The TLC determination method is simple to operate, has good specificity, and has no effect on negative results, and can be used for identification of Wufang Babu Poultice.
