期刊文献+
共找到11篇文章
< 1 >
每页显示 20 50 100
脊柱结核脓液中结核分枝杆菌的培养及菌种鉴定 被引量:10
1
作者 葛建忠 王自立 +2 位作者 秦世炳 李传友 张健源 《宁夏医学院学报》 2004年第4期251-252,261,F004,共4页
目的利用脊柱结核术中所取得的脓液进行结核分枝杆菌的培养及菌种鉴定,以了解脊柱结核感染菌种病源学的情况,为其病源学及耐药性方面的进一步研究做工作基础准备。方法将脊柱结核病灶中的脓液经前处理后接种于改良罗氏培养基上,4~8周... 目的利用脊柱结核术中所取得的脓液进行结核分枝杆菌的培养及菌种鉴定,以了解脊柱结核感染菌种病源学的情况,为其病源学及耐药性方面的进一步研究做工作基础准备。方法将脊柱结核病灶中的脓液经前处理后接种于改良罗氏培养基上,4~8周后观察结果和脓液涂片检查。结果143份脊柱结核脓液中,应用改良罗氏法培养出临床分离株13株,阳性率为301%;2涂片阳性者培养的阳性率较高;3化疗时间短、时间在两月以内者,其培养的阳性率较高;结论脊柱结核感染HIV阴性者的菌种以人型为主。 展开更多
关键词 脊柱结核 结核 分枝杆菌 菌种
下载PDF
Tuberculosis of the spine 被引量:2
2
作者 Wattana Leowattana Pathomthep Leowattana Tawithep Leowattana 《World Journal of Orthopedics》 2023年第5期275-293,共19页
Pott’s spine,commonly known as spinal tuberculosis(TB),is an extrapulmonary form of TB caused by Mycobacterium TB.Pott’s paraplegia occurs when the spine is involved.Spinal TB is usually caused by the hematogenous s... Pott’s spine,commonly known as spinal tuberculosis(TB),is an extrapulmonary form of TB caused by Mycobacterium TB.Pott’s paraplegia occurs when the spine is involved.Spinal TB is usually caused by the hematogenous spread of infection from a central focus,which can be in the lungs or another location.Spinal TB is distinguished by intervertebral disc involvement caused by the same segmental arterial supply,which can result in severe morbidity even after years of approved therapy.Neurological impairments and spine deformities are caused by progressive damage to the anterior vertebral body.The clinical,radiographic,microbiological,and histological data are used to make the diagnosis of spinal TB.In Pott’s spine,combination multidrug antitubercular therapy is the basis of treatment.The recent appearance of multidrug-resistant/extremely drug-resistant TB and the growth of human immunodeficiency virus infection have presented significant challenges in the battle against TB infection.Patients who come with significant kyphosis or neurological impairments are the only ones who require surgical care.Debride-ment,fusion stabilization,and correction of spinal deformity are the cornerstones of surgical treatment.Clinical results for the treatment of spinal TB are generally quite good with adequate and prompt care. 展开更多
关键词 TUBERCULOSIS pott’s disease Spinal tuberculosis KYPHOSIS Medical treatment of spinal tuberculosis Surgical treatment of spinal tuberculosis Drugs resistance
下载PDF
Extra-Pulmonary Pott’s Disease with Intracranial Manifestations: An Inmate’s Story 被引量:1
3
作者 Stephen M. Braden Ayman Yousef +2 位作者 Krishna Patel Carlos Dostal Michael Boyars 《Journal of Tuberculosis Research》 2021年第2期85-89,共5页
Tuberculosis is a chronic disease that is the leading cause of infectious disease deaths worldwide. In developed countries, incidences are minimal </span></span><span style="font-family:Verdana;&qu... Tuberculosis is a chronic disease that is the leading cause of infectious disease deaths worldwide. In developed countries, incidences are minimal </span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">and </span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">however</span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">,</span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;"> complicated manifestations of tuberculosis are becoming a trend within </span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">the prison system. This case report illustrates a patient within the United</span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;"> States correctional system who demonstrated a rare infection of tuberculosis despite absent pulmonary findings. Our Patient was a 39-year-old inmate presenting </span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">with fatigue, night sweats, weight loss, and progressive dyspnea. Pulmonary</span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;"> imaging and cultures of sputum were negative for tuberculosis. Further imaging and laboratory workups demonstrated extensive spinal infections along with intracranial lesions that were positive for tuberculosis. Neurosurgery declined operative medicine due to advancement of the disease and appropriate antibiotic therapy was immediately initiated. Tuberculosis continues to exist in de</span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Ve 展开更多
关键词 pott’s disease TUBERCULOSIS Spinal TB Tuberculosis Meningitis
下载PDF
脊柱结核脓液中结核分枝杆菌耐利福平基因检测的实验研究 被引量:1
4
作者 葛建忠 王自立 +5 位作者 秦世炳 乔永东 张健源 刘忠泉 张宗德 李传友 《中国脊柱脊髓杂志》 CAS CSCD 2004年第12期745-747,共3页
目的:探讨脊柱结核脓液中结核分枝杆菌对利福平(RFP)的耐药机制;评价聚合酶链反应-单链构象多态性(polymerasechainreactionsingle-strandconformationpolymorphism,PCR-SSCP)在脊柱结核检测耐RFP基因中的临床应用价值。方法:将脊柱结... 目的:探讨脊柱结核脓液中结核分枝杆菌对利福平(RFP)的耐药机制;评价聚合酶链反应-单链构象多态性(polymerasechainreactionsingle-strandconformationpolymorphism,PCR-SSCP)在脊柱结核检测耐RFP基因中的临床应用价值。方法:将脊柱结核病灶中的脓液经预处理后接种于改良罗氏培养基上,对所培养出的菌株应用PCR-SSCP进行检测。检测包括核心区域(耐药决定区域)在内的rpoB基因。结果:PCR-SSCP检测耐RFP菌株的灵敏度和特异性均为100%,与常规经典药物敏感试验无差异(P<0.05),但检测时间明显缩短,仅用2d。结论:rpoB基因突变是结核分枝杆菌对RFP耐药的重要机制,应用PCR-SSCP检测具有较高的灵敏性、特异性及快速性,是一种对脊柱结核耐RFP菌株快速检测的方法。 展开更多
关键词 脊柱结核 结核分枝杆菌 药物耐受性 聚合酶链反应-单链构象多态性
下载PDF
Tuberculous Spondylitis: Clinical Features of 36 Patients
5
作者 Halil Yanardag Cuneyt Tetikkurt +3 位作者 Muammer Bilir Sabriye Demirci Bulent Canbaz Mucahit Ozyazar 《Case Reports in Clinical Medicine》 2016年第10期411-417,共7页
We report 36 cases of spinal tuberculosis who were evaluated at the Internal Medicine Department of Istanbul University between January 1990 and March 2016. Twelve cases were accompanied by active pulmonary tuberculos... We report 36 cases of spinal tuberculosis who were evaluated at the Internal Medicine Department of Istanbul University between January 1990 and March 2016. Twelve cases were accompanied by active pulmonary tuberculosis while ten patients had a previous history of tuberculosis. Eight patients had diabetes mellitus;six patients were on chronic steroid treatment with a mean dose of 24 mg/day while two patients used azathioprine and methotrexate. The dominant symptom was back pain that was present in 64% of the subjects followed by low grade fever (42%), and malaise (38%). Lytic and destructive lesions were noted in various vertebrae in all of the cases while four patients had spinal compression, and two patients had iliopsoas abscess. The preliminary diagnosis was myeloproliferative disease with vertebral metastasis in eight patients. Tuberculin test was over 15 mm in 20 patients (58.8%) while ERS and Creactive protein were highly elevated in 78%, and 84% of the patients. Diagnosis of tuberculosis was confirmed by culture of aspirated material from intervertebral disc space, collection under CT guidance, sputum or bronchial lavage, and by retrospective anti-tuberculous treatment response. MRI revealed compatible findings with spinal tuberculosis in 30 (80%) patients. In endemic countries, tuberculous spondilitis should be considered in immunosuppressed patients with back pain. Current or past tuberculosis infection is not a reliable indicator for Pott’s disease in these patients. Laboratory findings were not usually useful to support the diagnosis. The low sensitivity of the tuberculin test may lead to an erronous diagnosis. Sensitivity of vertebral radiography and CT was low. MRI was the most useful radiologic investigation for the diagnosis of spinal tuberculosis. Tuberculosis of the spine is a diagnostic impasse notably in immunodeficient patients for the clinician. 展开更多
关键词 TUBERCULOSIS SPINAL VERTEBRAE M. Tuberculosis pott’s disease
下载PDF
C1-C2 Pott’s Disease, a Rare Location of Spine Tuberculosis
6
作者 Honoré Ntsiba Norbert Edgard Lamini N’Soundhat Daphtone Nkouala Kidédé 《Open Journal of Rheumatology and Autoimmune Diseases》 2013年第4期224-226,共3页
The authors report a new case of spine tuberculosis of C1-C2 occurred in a 58-year-old negative HIV patient that was responsible of inflammatory cervical pain with multidirectional stiffness and complicated by spastic... The authors report a new case of spine tuberculosis of C1-C2 occurred in a 58-year-old negative HIV patient that was responsible of inflammatory cervical pain with multidirectional stiffness and complicated by spastic quadriplegia. The diagnosis was made on the basis of presumptive elements, including cervical spinal CT scan, which showed atlan-to-axial subluxation (C1-C2) with destruction of the odontoid apophysis and lateral mass of the atlas and favorable evolution under specific antibiotic treatment with ethambutol, isoniazid, rifampicin, pyrazinamide and immobilization with brace cast, despite the absence of bacteriological and anatomo-pathological evidence of certainty. The evolution has been favorable, with the disappearance of cervical pain, progressive motor recovery and resumption of autonomy of walking. 展开更多
关键词 pott’s disease SPINE TUBERCULOSIS C1-C2 Atlanto-Axial
下载PDF
Multilevel Cervicothoracic and Lumbar Pott’s Disease: About Three New and Unusual Cases in the Rheumatology Department of the Teaching Hospital of Cocody in Abidjan (Côte d’Ivoire)
7
作者 Mohamed Diomandé Ehaulier Soh Christian Louis Kouakou +4 位作者 Tamo Estelle Mégné Mariam Gbané-Koné Abidou Kawele Coulibaly Edmond Eti Marcel N’zué Kouakou 《Open Journal of Rheumatology and Autoimmune Diseases》 2015年第2期23-27,共5页
Pott’s disease usually affects two contiguous vertebrae or two spinal levels. The involvement of the three cervicothoracic and lumbar levels is rarely described. Only three cases have been described in the literature... Pott’s disease usually affects two contiguous vertebrae or two spinal levels. The involvement of the three cervicothoracic and lumbar levels is rarely described. Only three cases have been described in the literature to our knowledge. The authors report three new cases of tuberculous spondylodiscitis of cervicothoracic and lumbar site. Our three cases were characterized by symptoms similar to the other topographical forms of Pott’s disease. A predisposing factor is often identified like the infection with human immunodeficiency virus. The definitive diagnosis was made in two cases by identifying acid and alcohol-fast bacilli for one case and by histology for the other case. For the third case, there was a diagnostic presumption reinforced by the satisfactory outcome on tuberculosis chemotherapy for a period of 12 months. The multilevel nature of diseases does not influence the effectiveness of treatment of this form of spinal tuberculosis. 展开更多
关键词 pott’s disease SPONDYLODISCITIS Bone and Joint Tuberculosis ABIDJAN
下载PDF
Child Spinal Cord Compression without Trauma about 113 Cases in Senegal
8
作者 Nourou Dine A. Bankole Moustapha Ndiaye +2 位作者 Thioub Mbaye Youssoupha Sakho Momar Code Ba 《Yangtze Medicine》 2018年第2期114-128,共15页
Introduction: No-trauma spinal cord compressions are serious conditions not often described in children population. This study will discuss the epidemiological, clinical, biology and radiology assessment, the etiologi... Introduction: No-trauma spinal cord compressions are serious conditions not often described in children population. This study will discuss the epidemiological, clinical, biology and radiology assessment, the etiologies, the therapeutic and evolutionary aspects of this condition in children in Senegal. Patients and Methods: 113 children aged between 15 months and 18 years were managed in a 10 years period (from January 2005 to July 2015) for a non-traumatic spinal cord compression (average 8.3 years). Results: There was 66 males (58%) and 47 females (42%) with sex ratio of 1.40. The main reasons for consultation were spinal deformity (90 %). The syndrome was complete in 52 patients (46%) and incomplete in 61 patients (54%). Plain radiography performed in 63 patients. The CT scan was performed in 21 patients and myelography performed in 4 patients. MRI was performed in 22 patients. There was intradural extramedullary process (33.33%), the extradural lesions (14.28%) and intramedullary process (28.57%). Dorsal lesions were predominant (46%) followed by the lumbar spine (27%). The majority of the etiology was Pott’s disease (80%) followed by tumors (17%). Spondylitis to banal germs (2%) and parasitic spinal cord compression (1%) were rare. The histology of 6 patients was revealed 5% neurofibroma Type II, 5% extramedullary intradermal arachnoid cyst, 5% intramedullary arachnoid cyst with cytochemistry of the CSF—like content, 5% Anaplastic pilocytic astrocytoma, 5% ganglioneuroma I terminal cone and 5% meningothelial meningioma. Pott’s disease has been cured by TB chemotherapy associated with a corset in 88.89% of cases. 2 patients of this group had benefited fixation after laminectomy. 68% of the patients had a favorable recovery, and 20% had completely recovered after an average of 7 months of treatment and three (3) patients had died. The compression by bilharzias is be cured by myelotomy and praziquantel with a favorable outcome. We have 94.74% decompressive laminectomy or laminotomy with tumor resection an 展开更多
关键词 SPINALCORD Compression CHILD pott’s disease TUMORS SPONDYLITIS Bilharzia
下载PDF
Atypical Presentation of Cervical Pott’s Disease: A Case Report
9
作者 Emecheta G. Okwudire Ugonna M. Ezenwugo +2 位作者 Johnpatrick U. Ugwoegbu Chika A. Okoro Ifeanyichukwu Isiozor 《Journal of Tuberculosis Research》 2021年第3期211-218,共8页
<span style="font-family:Verdana;">Tuberculous spondylitis, also known as Pott’s disease, </span><span><span><span style="font-family:;" "=""><span ... <span style="font-family:Verdana;">Tuberculous spondylitis, also known as Pott’s disease, </span><span><span><span style="font-family:;" "=""><span style="font-family:Verdana;">is due to infection of </span><span style="font-family:Verdana;">the spine </span></span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;" "="">by mycobacterium tuberculosis (MTB)</span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;" "=""> leading to </span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;" "="">vertebral body a</span></span></span><span><span><span style="font-family:;" "=""><span style="font-family:Verdana;">nd i</span><span style="font-family:Verdana;">nter-vertebral disc destruction</span></span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;" "="">. It is the most common form of musculo</span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;" "="">skeletal tuberculosis most frequently affecting the thoracolumbar spine and </span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;" "="">is commoner </span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;" "="">in young people. Onset of this condition is insidious and its clinical presentation is non specific. However, </span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;" "="">Pott’s</span></span></span><span><span><span style="font-family:;" "=""><span style="font-family:Verdana;"> disease may be complicated by </span><span style="font-family:Verdana;">neurologic deficits including paraplegia or even quadriplegia, with huge 展开更多
关键词 TUBERCULOSIS pott’s disease SPINE MRI HEMIPLEGIA
下载PDF
First Use of Bedaquiline in Democratic Republic of Congo: Two Case Series of Pre Extensively Drug Resistant Tuberculosis
10
作者 Murhula Innocent Kashongwe Leopoldine Mbulula +8 位作者 Brian Bakoko Pamphile Lubamba Murielle Aloni Simon Kutoluka Pierre Umba Luc Lukaso Michel Kaswa Jean Marie Ntumba Kayembe Zacharie Munogolo Kashongwe 《Journal of Tuberculosis Research》 2018年第2期125-134,共10页
In this manuscript the authors have studied the first two patients who were successfully treated with the treatment regimen containing Bedaquiline as second-line drug. The patients were diagnosed with pre-extensively ... In this manuscript the authors have studied the first two patients who were successfully treated with the treatment regimen containing Bedaquiline as second-line drug. The patients were diagnosed with pre-extensively drug-resistant tuberculosis (preXDR TB) whose prognosis was fatal in Democratic Republic of Congo (DRC). Bedaquiline is arguably one of the molecules of the future in the management of ultra-resistant tuberculosis. However, a larger cohort study may help to establish its effectiveness. Case report: Patients 1, 29 years old, with a history of multidrug-resistant TB (MDR-TB) one year previously. He showed signs of TB impregnation again 6 months after the last treatment. Bascilloscopy was positive again. The pre-extensively tuberculosis (pre-XDR TB) diagnosis was made by the Hain test (GenoType&reg;MTBDRsl, Hain Lifescience). Patient 2, brother of the first patient, with a history of MDR TB a year before. He had low back pain with right parietal dorso swelling four months after the last treatment. The x-ray of the column showed L4-L5 disc disease. Parietal ultrasound showed a parietal abscess to the right of thoracic vertebrae with fistulization. Surgical biopsy and pus culture confirmed the diagnosis of Pre-XDR Extrapulmonary TB. The treatment regimen was the same for both patients: 6 months with Amikacin (Am) Bedaquiline (Bdq) Prothionamide (Pto) Paraamino Salicylic acid (PAS) Linezolid (Lzd) Cycloserine (Cs) Pyrazinamide (Z) and 14 months with PAS Lzd Cs Z. The side effects were minor. Bacteriological controls (smears and cultures) after 20 months of treatment are negative to date. 展开更多
关键词 Pre-XDR TB pott’s disease Bedaquiline Molecular Technique Loweinstein CULTURE
下载PDF
Case of Unusual Abscess Localization in Lumbar Pott’s Disease
11
作者 Atchi Walla Anthony K. Beketi +3 位作者 Ibrahim Tine Faré Gnandi-Piou Komi Amakoutou Assang Dossim 《Open Journal of Orthopedics》 2018年第11期418-422,共5页
In Pott’s disease, cold abscesses usually sit and spread along the psoas muscle. This case concerned a 60 years old man who came to us with bilateral lomboradicular pain and a swelling of inguinal area and the anteri... In Pott’s disease, cold abscesses usually sit and spread along the psoas muscle. This case concerned a 60 years old man who came to us with bilateral lomboradicular pain and a swelling of inguinal area and the anterior part of the left thigh. We found a 2 years long lasting story of low back pain complaint. Physical examination showed good general health status, stiffness of lumber spine, a left psoitis and no neurological deficit. CT scan going downward from the lumbar spine to the pelvic region and femoral limb with coronal reconstruction demonstrated a huge disco-vertebral destruction of L2-L3 with translation, and bilateral paramedian psoas abscess migrating subfascially toward Scarpa triangle and cleaving anteriorly mainly muscles of the left thigh. After 12 months medical treatment, the evolution has been favorable with clinical cure. The localization of the cold abscess in the left thigh anterior muscles compatment is uncommon. It is why we report this case. 展开更多
关键词 LUMBAR pott’s disease THIGH ABSCESS Developing COUNTRY
下载PDF
上一页 1 下一页 到第
使用帮助 返回顶部