INTRODUCTIONThe word omentum derives from the ancientEgyptians who,when embalming human bodies,used to assess their'omens'by looking at thevariations in what we recognise today as theomentum.Galen(128-199 AD)t...INTRODUCTIONThe word omentum derives from the ancientEgyptians who,when embalming human bodies,used to assess their'omens'by looking at thevariations in what we recognise today as theomentum.Galen(128-199 AD)thought that therole of the omentum was to warm the intestines.This was on the basis of a gladiator who had anomental resection after a stab injury and sufferedgreatly from cold for the rest of his life.A展开更多
目的探讨严重外伤性脾破裂经脾切除治疗后行大网膜自体脾片种植的临床疗效。方法选取沈阳医学院附属中心医院2014年7月至2016年8月收治的42例严重外伤性脾破裂患者,分为观察组(23例)与对照组(19例)。患者或其家属签署知情同意书,并获得...目的探讨严重外伤性脾破裂经脾切除治疗后行大网膜自体脾片种植的临床疗效。方法选取沈阳医学院附属中心医院2014年7月至2016年8月收治的42例严重外伤性脾破裂患者,分为观察组(23例)与对照组(19例)。患者或其家属签署知情同意书,并获得我院医学伦理委员会批准。对照组行常规脾切除术,观察组在脾切除后行大网膜自体脾片种植。结果观察组的手术时间显著长于对照组(P<0.05),而术中出血量、术后进食时间及住院时间2组比较差异均无统计学意义(均P>0.05);观察组术后切口感染发生率显著低于对照组(P<0.05);观察组患者种植脾片全部显影良好;术后30 d内2组患者血小板均不同程度偏高,观察组增高程度显著低于对照组,术后3,7,14,30 d组间比较差异均有统计学意义(P<0.05);观察组术后28 d Ig G、Ig M、Ig A指标显著高于对照组(P<0.01);观察组术后14,28 d CD3+与CD4+/CD8+指标均较对照组显著增高(P<0.01)。结论严重外伤性脾破裂经脾切除治疗后行大网膜自体脾片种植可取得良好的临床疗效,具有较高的可行性与必要性。展开更多
AIM： To present our trial using a combination of the human acellular dermal matrix （HADM） implant and an interpositional omentum flap to repair giant abdominal wall defects after extensive tumor resection. METHODS...AIM： To present our trial using a combination of the human acellular dermal matrix （HADM） implant and an interpositional omentum flap to repair giant abdominal wall defects after extensive tumor resection. METHODS： Between February and October of 2007, three patients with giant defects of the abdominal wall after extensive tumor resection underwent reconstruction with a combination of HADN and omentum flap. Postoperative morbidities and signs of herniation were monitored. RESULTS： The abdominal wall reconstruction was successful in these three patients, there was no severe morbidity and no signs of herniation in the follow-up period. CONCLUSION： The combination of HADM and omentum flap offers a new, safe and effective alternative to traditional forms in the repair of giant abdominal wall defects. Further analysis of the long-term outcome and more cases are needed to assess the reliability of this technique.展开更多
The author reports a very rare case of sporadic primary multiple extragastrointestinal stromal tumors (EGISTs) of the omentum associated with different mutations of the exon 11 of the c-kit gene in a 75-year-old man w...The author reports a very rare case of sporadic primary multiple extragastrointestinal stromal tumors (EGISTs) of the omentum associated with different mutations of the exon 11 of the c-kit gene in a 75-year-old man with gastric cancer. During an operation for the cancer, two solid tumors (10 mm and 8 mm) were found in the omentum. Both tumors consisted of cellular spindle cells. Mitotic figures were two and three per 50 high power fields. The tumor cells were positive for KIT, CD34 and vimentin, but negative for desmin, S100 protein, α-smooth muscle actin and p53 protein. Ki67 labeling was 2% and 3%. The larger EGIST showed a deletion of codons 552-558 of exon 11 of the c-kit gene, while the smaller EGIST had a point mutation at codon 559 (GTT←GAT) in exon 11 of the c-kit gene. Exons 9, 13, and 17 of the c-kit gene, and exons 12 and 18 of the platelet derived growth factor receptor α genes showed no mutations. The case shows that sporadic multiple EGISTs can occur in the omentum.展开更多
文摘INTRODUCTIONThe word omentum derives from the ancientEgyptians who,when embalming human bodies,used to assess their'omens'by looking at thevariations in what we recognise today as theomentum.Galen(128-199 AD)thought that therole of the omentum was to warm the intestines.This was on the basis of a gladiator who had anomental resection after a stab injury and sufferedgreatly from cold for the rest of his life.A
文摘目的探讨严重外伤性脾破裂经脾切除治疗后行大网膜自体脾片种植的临床疗效。方法选取沈阳医学院附属中心医院2014年7月至2016年8月收治的42例严重外伤性脾破裂患者,分为观察组(23例)与对照组(19例)。患者或其家属签署知情同意书,并获得我院医学伦理委员会批准。对照组行常规脾切除术,观察组在脾切除后行大网膜自体脾片种植。结果观察组的手术时间显著长于对照组(P<0.05),而术中出血量、术后进食时间及住院时间2组比较差异均无统计学意义(均P>0.05);观察组术后切口感染发生率显著低于对照组(P<0.05);观察组患者种植脾片全部显影良好;术后30 d内2组患者血小板均不同程度偏高,观察组增高程度显著低于对照组,术后3,7,14,30 d组间比较差异均有统计学意义(P<0.05);观察组术后28 d Ig G、Ig M、Ig A指标显著高于对照组(P<0.01);观察组术后14,28 d CD3+与CD4+/CD8+指标均较对照组显著增高(P<0.01)。结论严重外伤性脾破裂经脾切除治疗后行大网膜自体脾片种植可取得良好的临床疗效,具有较高的可行性与必要性。
基金The Key Project of Science and Technology Commission of Shanghai Municipality,No. 074119649
文摘AIM： To present our trial using a combination of the human acellular dermal matrix （HADM） implant and an interpositional omentum flap to repair giant abdominal wall defects after extensive tumor resection. METHODS： Between February and October of 2007, three patients with giant defects of the abdominal wall after extensive tumor resection underwent reconstruction with a combination of HADN and omentum flap. Postoperative morbidities and signs of herniation were monitored. RESULTS： The abdominal wall reconstruction was successful in these three patients, there was no severe morbidity and no signs of herniation in the follow-up period. CONCLUSION： The combination of HADM and omentum flap offers a new, safe and effective alternative to traditional forms in the repair of giant abdominal wall defects. Further analysis of the long-term outcome and more cases are needed to assess the reliability of this technique.
文摘The author reports a very rare case of sporadic primary multiple extragastrointestinal stromal tumors (EGISTs) of the omentum associated with different mutations of the exon 11 of the c-kit gene in a 75-year-old man with gastric cancer. During an operation for the cancer, two solid tumors (10 mm and 8 mm) were found in the omentum. Both tumors consisted of cellular spindle cells. Mitotic figures were two and three per 50 high power fields. The tumor cells were positive for KIT, CD34 and vimentin, but negative for desmin, S100 protein, α-smooth muscle actin and p53 protein. Ki67 labeling was 2% and 3%. The larger EGIST showed a deletion of codons 552-558 of exon 11 of the c-kit gene, while the smaller EGIST had a point mutation at codon 559 (GTT←GAT) in exon 11 of the c-kit gene. Exons 9, 13, and 17 of the c-kit gene, and exons 12 and 18 of the platelet derived growth factor receptor α genes showed no mutations. The case shows that sporadic multiple EGISTs can occur in the omentum.
