A middle Paleozoic subduction-collision orogenic belt between the Siberian and North China Plates has been recognized in Xilinhot-the south of Sonid Left Banner-Erdaojing area, northern Inner Mongolia, China. It compr...A middle Paleozoic subduction-collision orogenic belt between the Siberian and North China Plates has been recognized in Xilinhot-the south of Sonid Left Banner-Erdaojing area, northern Inner Mongolia, China. It comprises five subunits: melange belt, foreland deformation belt, molasse and littoral basin, arc diorite series and syn-collision granitoid series. Evolution history of the orogenic belt can be divided into subduction stage (500-400 Ma) and collision stage (400-320 Ma). The formation of the orogenic belt caused the convergence between the Siberian and North China Plates during the late Devonian. Suture zone corresponding to the melange belt extends from Erdao-jing, Qagan Ura to Honggor.展开更多
The shallow shelf delta/strand arenaceous-pelitic deposit region in the north of the Pearl River mouth basin, sitting on the northern continental shelf of the South China Sea, has already become an important oil produ...The shallow shelf delta/strand arenaceous-pelitic deposit region in the north of the Pearl River mouth basin, sitting on the northern continental shelf of the South China Sea, has already become an important oil production base in China. Recent researched has revealed that a great deal of deep-water fans of great petroleum potentiality exist on the Baiyun deep-water slope below the big paleo Pearl River and its large delta. Based on a mass of exploration wells and 2-D seismic data of the shallow shelf region, a interpretation of sequence stratigraphy confirmed the existence of deep-water fans. The cyclic falling of sea level, abundant detrital matter from the paleo Pearl River and the persistent geothermal subsidence in the Baiyun sag are the three prerequisites for the formation and development of deep-water fans. There are many in common between the deep-water shelf depositional system of the northern South China Sea and the exploration hotspots region on the two banks of the Atlantic. For example, both are located on passive continent margins, and persistent secular thermal subsidence and large paleo rivers have supplied abundant material sources and organic matter. More recently, the discovery of the big gas pool on the northern slope of the Baiyun sag confirms that the Lower Tertiary lacustrine facies in the Baiyun sag has a great potentiality of source rocks. The fans overlying the Lower Tertiary source rocks should become the main exploration areas for oil and gas resources.展开更多
Long non-coding RNAs(lncRNAs),which represent a new frontier in molecular biology,play important roles in regulating gene expression at epigenetic,transcriptional and post-transcriptional levels.More and more lncRNAs ...Long non-coding RNAs(lncRNAs),which represent a new frontier in molecular biology,play important roles in regulating gene expression at epigenetic,transcriptional and post-transcriptional levels.More and more lncRNAs have been found to play important roles in normal cell physiological activities,and participate in the development of varieties of tumors and other diseases.Previously,we have only been able to determine the function of lncRNAs through multiple mechanisms,including genetic imprinting,chromatin remodeling,splicing regulation,mRNA decay,and translational regulation.Application of technological advances to research into the function of lncRNAs is extremely important.The major tools for exploring lncRNAs include microarrays,RNA sequencing(RNA-seq),Northern blotting,real-time quantitative reverse transcription-polymerase chain reaction(qRT-PCR),fluorescence in situ hybridization(FISH),RNA interference(RNAi),RNA-binding protein immunoprecipitation(RIP),chromatin isolation by RNA purification(ChIRP),crosslinking-immunopurification(CLIP),and bioinformatic prediction.In this review,we highlight the functions of lncRNAs,and advanced methods to research lncRNA-protein interactions.展开更多
AIM To find out the relationship between the gene transcription of different types ofprocollagen and the deposition of the relevant collagens in the liver tissue and to confirm the types of collagen producing cells in...AIM To find out the relationship between the gene transcription of different types ofprocollagen and the deposition of the relevant collagens in the liver tissue and to confirm the types of collagen producing cells in liverfibrogenesis.METHODS Dynamic changes of the expression of α1(Ⅰ ), α1 (Ⅲ ) and α1 (Ⅳ) procollagen mRNAand relevant collagens and the distribution ofcollagen producing cells during liver fibrogenesis of rat induced by CCl4 (20 weeks)were investigated with Northern blot analysis,in situ hybridization and immunohistochemicaltechniques.RESULTS The increased expression of α1 (Ⅲ)procollagen mRNA by Northern blot analysis was the most predominant one among the threemRNAs during fibrogenesis. However, theenhanced expression of al (Ⅳ) procollagenmRNA occurred very early while the expressionof α1 (Ⅰ) mRNA was not enhanced much until themiddle stage of the exPeriment. D6smin (Dm)positive hepatic stellate cells (HSCs) and fewmyofibroblasts (MFs) in and around the necrotic areas expressed α1 (Ⅰ), α1 (Ⅲ) and α1 (Ⅳ)procollagen mRNA signals detected by in situhybridization at the early stage of theexperiment. All the three procollagen mRNAsignals thereafter mainly localized in fibroblasts (Fbs) and MFs in fibrotic septa during the middle and late stages of fibrosis, which distributedparallel to the corresponding collagens detected by immunohistochemical study. ln addition, the endothelial cells of sinusoids and the small blood vessels within the septa also showed α1(Ⅳ) procollagen mRNA and type Ⅳ collagen expressionCONCLUSION It is considered that "HSC-MF-Fb" effect cell system is the major cellularsource of collagen production in liver fibrosis, in which HSCs are collagen producing precursor cells in the early liver fibrogenesis, thereafter the synthesis of type Ⅰ, Ⅲ and Ⅳ collagens (Col Ⅰ, Col Ⅲ and Col Ⅳ) mainly derives fromMFs and Fbs, which play a very important role in the progress of liver fibrosis. The endothelialcells along sinusoids, as another source of Col 展开更多
We here report our recent research results on the climatic features of Tibetan thermodynamic functions and their impacts on the regional climates of the Northern Hemisphere. The results show that the thermodynamic pro...We here report our recent research results on the climatic features of Tibetan thermodynamic functions and their impacts on the regional climates of the Northern Hemisphere. The results show that the thermodynamic processes over the Tibetan Plateau not only strongly influence the Asian monsoon and precipitation, but also modulate the atmospheric circulation and climate over North America and Europe through stimulating the large-scale teleconnections such as the Asian-Pacific oscillation and affect the atmospheric circulation over the southern Indian Ocean. The Tibetan climate may be affected by sea surface temperatures over the tropical Pacific. On the other hand, the Tibetan climate also affects the atmosphere-ocean interactions in the tropics and mid-latitudes of the Pacific by the atmospheric circulation over the North Pacific. In spring and summer, the thermodynamic anomalies on the plateau affect the subtropical high pressure, the Hadley circulation, and the intertropical convergence zone over the Pacific, and then modulate the development of the El Ni-o/Southern Oscillation (ENSO). It is necessary to study the forecasting methods for the development of ENSO from the Tibetan climate anomaly. This result also embodies the essence of interactions among land, atmosphere, and ocean over the Northern Hemisphere. Since the previous studies focused on impacts of the plateau on climates in the Asian monsoon regions, it is essential to pay more attention to studying the roles of the plateau in the Northern Hemispheric and even global climates.展开更多
205 surface pollen samples from different communities in Northern China were analyzed to understand the quantitative relationship between pollen and its original vegetation. Pollen analysis and vegetation investigatio...205 surface pollen samples from different communities in Northern China were analyzed to understand the quantitative relationship between pollen and its original vegetation. Pollen analysis and vegetation investigation show that the pollen assemblages differ a lot in different vegetation regions. Arboreal pollen account for more than 30% in temperate broad-deciduous forests region. In temperate steppe regions, herb pollen percentages are more than 90%, where Artemisia and Chenopodiaceae are domi- nant pollen types with Artemisia percentages more than 30%. In temperate desert, Chenopodiaceae pollen percentages are more than Artemisia, where ferns are rare. Cyperaceae pollen percentages are more than 20% in sub-alpine or cold meadows. The relations between pollen percentages and vegeta- tion cover indicate that most arboreal pollen shows a close relationship with parent plant covers, most shrubby pollen types have more or less correlations, but most herbs do not show clear correlations. For arboreal pollen types, Picea pollen shows the closest correlation with spruce trees coverage, then is Quercus and Carpinus. Betula, Larix and Juglans have also high correlation coefficients with their plants coverage, but Betula pollen is of overrepresented pollen type and more than 40% in birch forest, while Larix and Juglans pollen is underrepresented and pollen percentages are more than 10% in Larix or Juglans pure forests. Pinus is of overrepresented pollen type, and pollen percentages have some relations with plants cover. Pine forest might present when Pinus pollen percentages are more than 30%. The relations between Ulmus and Populus pollen percentages and vegetation cover are not close, where they are mixed with other arbors, they cannot be recorded easily, but if their pollen percentages are more than 1%, Ulmus or Populus trees should exist. For shrubby pollen types, the correlation be- tween Vitex pollen percentages and vegetation cover is the highest, then is Corylus, Tamariaceae and Nitraria, and their pollen percent展开更多
Three well-dated Sabina Przewalskii ring-width chronologies from Dulan, China, have been used to reconstruct annual precipitation (from prior July to current June) variations on the northeast Tibetan Plateau since 850...Three well-dated Sabina Przewalskii ring-width chronologies from Dulan, China, have been used to reconstruct annual precipitation (from prior July to current June) variations on the northeast Tibetan Plateau since 850 AD. The reconstructions account of the instrumentally recorded precipitation variance are: 54.7% for the period of 1385-2000AD; 50.5% for 1099-1384AD and 45.7% for 850-1098AD. On the millenary scale, the precipitation variation over this region displays “W” shape, which has three peaks and two valleys. The precipitation is low during 1571-1879 AD, and high during 1880-2000 AD. 1900-2000 AD is the century with the highest precipitation over the northeast Tibetan Plateau in the last 1000 years, and 1962-2000 is the period with the highest pre- cipitation, and the highest variability of precipitation as well in the last 1000 years. The reconstructed series also reveals that the variability of annual precipitation is large when the precipitation is more, and contrarily, variability is small when the precipitation is low. With the temperature increasing obvi- ously in the 20th century, the precipitation in the study region significantly increased too, the variability of precipitation became larger, and drought and flooding occurred more frequently. The yearly tree-ring width (high frequency signal) series in this region reflects the local annually precipitation variation. However, the series with 40-year moving average (low frequency signal) cor- responds to the Northern Hemisphere temperature variations on the decadal to centurial scale. It correlates significantly with seven temperature curves of the Northern Hemisphere in the different time spans. For example, the correlation coefficients with the most temperature curves are around 0.9 during the period of 1852-1982 AD. In general, the temperature and the precipitation change syn- chronously in the Dulan region. It means that low temperature corresponds to low precipitation, andvice versa. This relationship may indicate that the climatic pattern i展开更多
In this paper we present a review of mineral systems in northern Xinjiang, NW China, focussing on the Tianshan, West and East Junggar and Altay orogenic belts, all of which are part of the greater Central Asian Orogen...In this paper we present a review of mineral systems in northern Xinjiang, NW China, focussing on the Tianshan, West and East Junggar and Altay orogenic belts, all of which are part of the greater Central Asian Orogenic Belt （CAOB）. The CAOB is a complex collage of ancient microcontinents, island arcs, oceanic plateaux and oceanic plates, which were amalgamated and accreted in Early Palaeozoic to Early Permian times. The establishment of the CAOB collage was followed by strike-slip movements and affected by intraplate magmatism, linked to mantle plume activity, best exemplified by the 250 Ma Siberian Traps and the 280 Ma Tarim event. In northern Xinjiang, there ale numerous and economically important mineral systems. In this contribution we describe a selection of representative mineral deposits, including subduction-related porphyry and epithermal deposits, volcanogenic massive sulphides and skarn systems. Shear zone-hosted Au lodes may have first formed as intrusion-related and subsequently re-worked during strike-slip deformation. Intraplate magmatism led to the emplacement of concentrically zoned （Alaskan-style） mafic-ultramafic intrusions, many of which host orthomagmatic sulphide deposits. A huge belt of pegmatites in the Altay orogen, locally hosts world-class rare metal deposits. Roll-front,展开更多
On the basis of a newly-constructed record of magnetic susceptibility (SUS) and the depositional rate change of eolian loess-red clay sequences in the last 7.2 Ma BP from the hea Plateau, together with a cornperison o...On the basis of a newly-constructed record of magnetic susceptibility (SUS) and the depositional rate change of eolian loess-red clay sequences in the last 7.2 Ma BP from the hea Plateau, together with a cornperison of a record of °18O values from the equatorial East Pacific Ocean and eolian Quartz flux variations fmm the North Pacific Ocean, the evolutiomuy process of the Late Cenozoic Great Glaciation in the Northern Hemisphere can be divided into three stages: the arrival stage around 7.2–3.4 Ma BP, the initial stage at about 3.4—2.6 Ma BP, and the Great Ice Age since 2.6 Ma BP. The evolution of the East Asian monsoon is characterized by paid winter and summer monsoons, and it is basically composed of the initial stage of weak winter and summer monsoons, the transitional stage of simultaneous increase in intensity of winter and summer monsoons, and the prevailing stage of strong winter and week summer monsoons, or weak winter and strong summer monsoons. The Late Cenowic global tectonic uplift, paaicdarly the Qinghai-Xizang Plateau uplift and the associated CO2 concentration variation, controls the dng processes of the onset of Great Glaciation and the long-term changes of East Asian monsoom climate in the Northern Hemisphere to a large extent. The accelerating uplift of the Qinghai-Xizang Plateau between 3.4 and 2.6 Ma BP provided an important driving force to global climiatic change.展开更多
Eclogite from the Northern Dabie Mountain is a new finding by the authors. These eclogites in foliated perdotite are enveloped by banded gneiss and occur in the mafic-ultramafic rock belt. They are mainly composed of ...Eclogite from the Northern Dabie Mountain is a new finding by the authors. These eclogites in foliated perdotite are enveloped by banded gneiss and occur in the mafic-ultramafic rock belt. They are mainly composed of omphacite, garnet, diopside, orthopyroxene, amphibole, plagioclase and magnetite, and a small amount of rutile, spinel, olivin and 鏾rundum. The mineral association of peak metamorphism of the eclogite is omphacite+garnet+rutile. The existence of eclogite in the Northern Dabie Mountain implies that there was an eclogitic metamorphism prior to the granulitic facies one in the mafic-ultramafic rock belt.展开更多
Distribution of vegetation is closely coupled with climate; the climate controls distribution of vegetation and the vegetation type reflects regional climates. To reveal vegetation_climate relationships is the foundat...Distribution of vegetation is closely coupled with climate; the climate controls distribution of vegetation and the vegetation type reflects regional climates. To reveal vegetation_climate relationships is the foundation for understanding the vegetation distribution and theoretically serving vegetation regionalization. Vegetation regionalization is a theoretical integration of vegetation studies and provides a base for physiogeographical regionalization as well as agriculture and forestry regionalization. Based on a brief historical overview on studies of vegetation_climate relationships and vegetation regionalization conducted in China, we review the principles, bases and major schemes of previous vegetation regionalization and discuss on several contentious boundaries of vegetation zones in the present paper. We proposed that, under the circumstances that the primary vegetation has been destroyed in most parts of China, the division of vegetation zones/regions should be based on the distribution of primary and its secondary vegetation types and climatic indices that delimit distribution of the vegetation types. This not only reveals the closed relationship between vegetation and climate, but also is feasible practically. Although there still are divergence of views on the name and their boundaries of the several vegetation zones, it is commonly accepted that there are eight major vegetation regions in China, i.e. cold temperate needleleaf forest region, temperate needleleaf and broadleaf mixed forest region, warm temperate deciduous broadleaf forest region, subtropical evergreen broadleaf forest region, tropical monsoon forest and rain forest region, temperate steppe region, temperate desert region, and Qinghai_Xizang (Tibetan) Plateau high_cold vegetation region. Analyzing characteristics of vegetation and climate of major vegetation boundaries, we suggested that: 1) Qinling Mountain_Huaihe River line is an important arid/humid climatic, but not a thermal climatic boundary, and thus can not also be regarde展开更多
Based on water quality surveys over 2 years （July to December, in 2014 and 2015） in a typical arid fiver in northern China the Xingtai segment of the Yuyang River basin - the variation of nitrogen （N） and phosphor...Based on water quality surveys over 2 years （July to December, in 2014 and 2015） in a typical arid fiver in northern China the Xingtai segment of the Yuyang River basin - the variation of nitrogen （N） and phosphorus （P） was analyzed. The extent of water eutrophication of this segment was also assessed using a universal index formula for eutrophic evaluation and a logarithmic power function. The results showed that the average concentration of total N （TN） was 27.2 mg/L （NH3-N, 63.5% ）, total P （TP） was 2.0 mg/L （solution reactive phosphorus, 68.8%）. Temporal and spatial variations of N and P in this segment were observed. Concentrations of N and P in the arid season were higher than those in the rainy season. Spatially, the N and P concentrations followed the same trend; i.e., higher in the city segment than in the suburbs, and decreasing along the river. The water eutrophication in the studied segment reached extremely high levels at all times （eutrophication index ≥76.3）. Spatially, its trend was clearly linked with N and P. Water shortage, pollution accumulation and a weak self-purification function are the main reasons for the prominent eutrophication in this segment.展开更多
This paper reviews recent progress made by Chinese scientists on the pathways of influence of the Northern Hemisphere mid-high latitudes on East Asian climate within the framework of a“coupled oceanic-atmospheric(lan...This paper reviews recent progress made by Chinese scientists on the pathways of influence of the Northern Hemisphere mid-high latitudes on East Asian climate within the framework of a“coupled oceanic-atmospheric(land-atmospheric or seaice-atmospheric)bridge”and“chain coupled bridge”.Four major categories of pathways are concentrated upon,as follows:Pathway A—from North Atlantic to East Asia;Pathway B—from the North Pacific to East Asia;Pathway C—from the Arctic to East Asia;and Pathway D—the synergistic effects of the mid-high latitudes and tropics.In addition,definitions of the terms“combined effect”,“synergistic effect”and“antagonistic effect”of two or more factors of influence or processes and their criteria are introduced,so as to objectively investigate those effects in future research.展开更多
A two-year field experiment(2012–2013) was conducted to investigate the effects of two tillage methods and five maize straw mulching patterns on the yield, water consumption,and water use efficiency(WUE) of spring ma...A two-year field experiment(2012–2013) was conducted to investigate the effects of two tillage methods and five maize straw mulching patterns on the yield, water consumption,and water use efficiency(WUE) of spring maize(Zea mays L.) in the northern Huang–Huai–Hai valley of China. Compared to rotary tillage, subsoil tillage resulted in decreases in water consumption by 6.3–7.8% and increases in maize yield by 644.5–673.9 kg ha-1, soil water content by 2.9–3.0%, and WUE by 12.7–15.2%. Chopped straw mulching led to higher yield,soil water content, and WUE as well as lower water consumption than prostrate whole straw mulching. Mulching with 50% chopped straw had the largest positive effects on maize yield, soil water content, and WUE among the five mulching treatments. Tillage had greater influence on maize yield than straw mulching, whereas straw mulching had greater influence on soil water content, water consumption, and WUE than tillage. These results suggest that 50% chopped straw mulching with subsoil tillage is beneficial in spring maize production aiming at high yield and high WUE in the Huang–Huai–Hai valley.展开更多
Recent mapping and seismic survey reveal that intensive compression during the Early Cenozoic in the Qiangtang block of the central Tibetan Plateau formed an extensive complex of thrust sheets that moved relatively so...Recent mapping and seismic survey reveal that intensive compression during the Early Cenozoic in the Qiangtang block of the central Tibetan Plateau formed an extensive complex of thrust sheets that moved relatively southward along several generally north-dipping great thrust systems. Those at the borders of the ~450 km wide block show it overrides the Lhasa block to the south and is overridden by the Hohxil-Bayanhar block to the north. The systems are mostly thin-skinned imbricate thrusts with associated folding. The thrust sheets are chiefly floored by Jurassic limestone that apparently slid over Triassic sandstone and shale, which is locally included, and ramped upward and over Paleocene-Eocene red-beds. Some central thrusts scooped deeper and carried up Paleozoic metamorphic rock, Permian carbonate and granite to form a central uplift that divides the Qiangtang block into two parts. These systems and their associated structures are unconformably overlain by little deformed Late Eocene-Oligocene volcanic rock or capped by Miocene lake beds. A thrust system in the northern part of the block, as well as one in the northern part of the adjacent Lhasa block, dip to the south and appear to be due to secondary adjustments within the thrust sheets. The relative southward displacement across this Early Cenozoic mega thrust system is in excess of 150 km in the Qiangtang block, and the average southward slip-rate of the southern Qiangtang thrusts ranged from 5.6 mm to 7.4 mm/a during the Late Eocene-Oligocene. This Early Cenozoic thrusting ended before the Early Miocene and was followed by Late Cenozoic crustal extension and strike-slip faulting within the Qiangtang block. The revelation and understanding of these thrust systems are very important for the evaluation of the petroleum resources of the region.展开更多
The Pengjiakuang, Dazhuangzi and Fayunkuang gold deposits, located on the northern margin of the Mesozoic Jiaolai Basin, east of Shandong Province, are controlled by a low-angle normal fault. Gold ores are typically b...The Pengjiakuang, Dazhuangzi and Fayunkuang gold deposits, located on the northern margin of the Mesozoic Jiaolai Basin, east of Shandong Province, are controlled by a low-angle normal fault. Gold ores are typically brecciated, veinlet and disseminated. The Ar-Ar and Rb-Sr isochron dating methods were adopted to date ores and lamprophyre dike. The results indicate that the age of the Pengjiakuang gold deposit is 117.33—118.42 Ma, that of the Dazhuangzi gold deposit is 117.39 Ma, and that of the Fayunkuang gold deposit is (128.49±7.2) Ma. The consistency in metallogenic age between the gold deposits on the margin of the Jiaolai Basin and the gold deposits (115—126 Ma) of the northern uplift area suggests that both were formed in the same metallogenic period. That is to say, the large-scale metallogeny of the Jiaodong region took place in late-Yanshannian ((120±10) Ma).展开更多
基金Project supported by Fok Ying Tung Education Foundation in Hong Kong
文摘A middle Paleozoic subduction-collision orogenic belt between the Siberian and North China Plates has been recognized in Xilinhot-the south of Sonid Left Banner-Erdaojing area, northern Inner Mongolia, China. It comprises five subunits: melange belt, foreland deformation belt, molasse and littoral basin, arc diorite series and syn-collision granitoid series. Evolution history of the orogenic belt can be divided into subduction stage (500-400 Ma) and collision stage (400-320 Ma). The formation of the orogenic belt caused the convergence between the Siberian and North China Plates during the late Devonian. Suture zone corresponding to the melange belt extends from Erdao-jing, Qagan Ura to Honggor.
基金This study was supported by the project“the deep-water fan systems and petroleum resources in the South China Sea”(grant 40238060)sponsored by the Natural Science Foundation of China and the China National Offshore Oil Corporation.
文摘The shallow shelf delta/strand arenaceous-pelitic deposit region in the north of the Pearl River mouth basin, sitting on the northern continental shelf of the South China Sea, has already become an important oil production base in China. Recent researched has revealed that a great deal of deep-water fans of great petroleum potentiality exist on the Baiyun deep-water slope below the big paleo Pearl River and its large delta. Based on a mass of exploration wells and 2-D seismic data of the shallow shelf region, a interpretation of sequence stratigraphy confirmed the existence of deep-water fans. The cyclic falling of sea level, abundant detrital matter from the paleo Pearl River and the persistent geothermal subsidence in the Baiyun sag are the three prerequisites for the formation and development of deep-water fans. There are many in common between the deep-water shelf depositional system of the northern South China Sea and the exploration hotspots region on the two banks of the Atlantic. For example, both are located on passive continent margins, and persistent secular thermal subsidence and large paleo rivers have supplied abundant material sources and organic matter. More recently, the discovery of the big gas pool on the northern slope of the Baiyun sag confirms that the Lower Tertiary lacustrine facies in the Baiyun sag has a great potentiality of source rocks. The fans overlying the Lower Tertiary source rocks should become the main exploration areas for oil and gas resources.
基金supported by the National Basic Research Program of China(2010CB912801,2013CB910801)National High Technology Research and Development Program of China(2012AA022501)National Natural Science Foundation of China(31070702,31270836)
文摘Long non-coding RNAs(lncRNAs),which represent a new frontier in molecular biology,play important roles in regulating gene expression at epigenetic,transcriptional and post-transcriptional levels.More and more lncRNAs have been found to play important roles in normal cell physiological activities,and participate in the development of varieties of tumors and other diseases.Previously,we have only been able to determine the function of lncRNAs through multiple mechanisms,including genetic imprinting,chromatin remodeling,splicing regulation,mRNA decay,and translational regulation.Application of technological advances to research into the function of lncRNAs is extremely important.The major tools for exploring lncRNAs include microarrays,RNA sequencing(RNA-seq),Northern blotting,real-time quantitative reverse transcription-polymerase chain reaction(qRT-PCR),fluorescence in situ hybridization(FISH),RNA interference(RNAi),RNA-binding protein immunoprecipitation(RIP),chromatin isolation by RNA purification(ChIRP),crosslinking-immunopurification(CLIP),and bioinformatic prediction.In this review,we highlight the functions of lncRNAs,and advanced methods to research lncRNA-protein interactions.
基金supported by National Natural Science Foundation of China(No.3933140)Shanghai Municipal Education Commission(No.980802).
文摘AIM To find out the relationship between the gene transcription of different types ofprocollagen and the deposition of the relevant collagens in the liver tissue and to confirm the types of collagen producing cells in liverfibrogenesis.METHODS Dynamic changes of the expression of α1(Ⅰ ), α1 (Ⅲ ) and α1 (Ⅳ) procollagen mRNAand relevant collagens and the distribution ofcollagen producing cells during liver fibrogenesis of rat induced by CCl4 (20 weeks)were investigated with Northern blot analysis,in situ hybridization and immunohistochemicaltechniques.RESULTS The increased expression of α1 (Ⅲ)procollagen mRNA by Northern blot analysis was the most predominant one among the threemRNAs during fibrogenesis. However, theenhanced expression of al (Ⅳ) procollagenmRNA occurred very early while the expressionof α1 (Ⅰ) mRNA was not enhanced much until themiddle stage of the exPeriment. D6smin (Dm)positive hepatic stellate cells (HSCs) and fewmyofibroblasts (MFs) in and around the necrotic areas expressed α1 (Ⅰ), α1 (Ⅲ) and α1 (Ⅳ)procollagen mRNA signals detected by in situhybridization at the early stage of theexperiment. All the three procollagen mRNAsignals thereafter mainly localized in fibroblasts (Fbs) and MFs in fibrotic septa during the middle and late stages of fibrosis, which distributedparallel to the corresponding collagens detected by immunohistochemical study. ln addition, the endothelial cells of sinusoids and the small blood vessels within the septa also showed α1(Ⅳ) procollagen mRNA and type Ⅳ collagen expressionCONCLUSION It is considered that "HSC-MF-Fb" effect cell system is the major cellularsource of collagen production in liver fibrosis, in which HSCs are collagen producing precursor cells in the early liver fibrogenesis, thereafter the synthesis of type Ⅰ, Ⅲ and Ⅳ collagens (Col Ⅰ, Col Ⅲ and Col Ⅳ) mainly derives fromMFs and Fbs, which play a very important role in the progress of liver fibrosis. The endothelialcells along sinusoids, as another source of Col
基金Supported by National Natural Science Foundation of China (Grant Nos. 40890052, 40921003)the Chinese COPES Project (Grant No. GYHY200706005)
文摘We here report our recent research results on the climatic features of Tibetan thermodynamic functions and their impacts on the regional climates of the Northern Hemisphere. The results show that the thermodynamic processes over the Tibetan Plateau not only strongly influence the Asian monsoon and precipitation, but also modulate the atmospheric circulation and climate over North America and Europe through stimulating the large-scale teleconnections such as the Asian-Pacific oscillation and affect the atmospheric circulation over the southern Indian Ocean. The Tibetan climate may be affected by sea surface temperatures over the tropical Pacific. On the other hand, the Tibetan climate also affects the atmosphere-ocean interactions in the tropics and mid-latitudes of the Pacific by the atmospheric circulation over the North Pacific. In spring and summer, the thermodynamic anomalies on the plateau affect the subtropical high pressure, the Hadley circulation, and the intertropical convergence zone over the Pacific, and then modulate the development of the El Ni-o/Southern Oscillation (ENSO). It is necessary to study the forecasting methods for the development of ENSO from the Tibetan climate anomaly. This result also embodies the essence of interactions among land, atmosphere, and ocean over the Northern Hemisphere. Since the previous studies focused on impacts of the plateau on climates in the Asian monsoon regions, it is essential to pay more attention to studying the roles of the plateau in the Northern Hemispheric and even global climates.
基金Supported by the Special Foundation for Preliminary Research of Key Research Project Science and Technology Ministry of China (Grant No.2003CCA01800)the National Natural Science Foundation of China (Grant No. 40571166)+1 种基金the Key Na-tional Natural Science Foundation (Grant No. 40331011) the Special Foundation for Doctorate Authorized Units of Ministry of Education (Grant No. 49920205)
文摘205 surface pollen samples from different communities in Northern China were analyzed to understand the quantitative relationship between pollen and its original vegetation. Pollen analysis and vegetation investigation show that the pollen assemblages differ a lot in different vegetation regions. Arboreal pollen account for more than 30% in temperate broad-deciduous forests region. In temperate steppe regions, herb pollen percentages are more than 90%, where Artemisia and Chenopodiaceae are domi- nant pollen types with Artemisia percentages more than 30%. In temperate desert, Chenopodiaceae pollen percentages are more than Artemisia, where ferns are rare. Cyperaceae pollen percentages are more than 20% in sub-alpine or cold meadows. The relations between pollen percentages and vegeta- tion cover indicate that most arboreal pollen shows a close relationship with parent plant covers, most shrubby pollen types have more or less correlations, but most herbs do not show clear correlations. For arboreal pollen types, Picea pollen shows the closest correlation with spruce trees coverage, then is Quercus and Carpinus. Betula, Larix and Juglans have also high correlation coefficients with their plants coverage, but Betula pollen is of overrepresented pollen type and more than 40% in birch forest, while Larix and Juglans pollen is underrepresented and pollen percentages are more than 10% in Larix or Juglans pure forests. Pinus is of overrepresented pollen type, and pollen percentages have some relations with plants cover. Pine forest might present when Pinus pollen percentages are more than 30%. The relations between Ulmus and Populus pollen percentages and vegetation cover are not close, where they are mixed with other arbors, they cannot be recorded easily, but if their pollen percentages are more than 1%, Ulmus or Populus trees should exist. For shrubby pollen types, the correlation be- tween Vitex pollen percentages and vegetation cover is the highest, then is Corylus, Tamariaceae and Nitraria, and their pollen percent
基金supported by the National Natural Science Foundation of China(Grant Nos.40525004,90211018,50279010,40531003 and 40121303)the Ministry of Science and Technology of China(Grant No.2004CB720206).
文摘Three well-dated Sabina Przewalskii ring-width chronologies from Dulan, China, have been used to reconstruct annual precipitation (from prior July to current June) variations on the northeast Tibetan Plateau since 850 AD. The reconstructions account of the instrumentally recorded precipitation variance are: 54.7% for the period of 1385-2000AD; 50.5% for 1099-1384AD and 45.7% for 850-1098AD. On the millenary scale, the precipitation variation over this region displays “W” shape, which has three peaks and two valleys. The precipitation is low during 1571-1879 AD, and high during 1880-2000 AD. 1900-2000 AD is the century with the highest precipitation over the northeast Tibetan Plateau in the last 1000 years, and 1962-2000 is the period with the highest pre- cipitation, and the highest variability of precipitation as well in the last 1000 years. The reconstructed series also reveals that the variability of annual precipitation is large when the precipitation is more, and contrarily, variability is small when the precipitation is low. With the temperature increasing obvi- ously in the 20th century, the precipitation in the study region significantly increased too, the variability of precipitation became larger, and drought and flooding occurred more frequently. The yearly tree-ring width (high frequency signal) series in this region reflects the local annually precipitation variation. However, the series with 40-year moving average (low frequency signal) cor- responds to the Northern Hemisphere temperature variations on the decadal to centurial scale. It correlates significantly with seven temperature curves of the Northern Hemisphere in the different time spans. For example, the correlation coefficients with the most temperature curves are around 0.9 during the period of 1852-1982 AD. In general, the temperature and the precipitation change syn- chronously in the Dulan region. It means that low temperature corresponds to low precipitation, andvice versa. This relationship may indicate that the climatic pattern i
基金funded by"State Key Laboratory of Geological Processes and Mineral Resources(GPMR200624),China University of Geosciences"
文摘In this paper we present a review of mineral systems in northern Xinjiang, NW China, focussing on the Tianshan, West and East Junggar and Altay orogenic belts, all of which are part of the greater Central Asian Orogenic Belt （CAOB）. The CAOB is a complex collage of ancient microcontinents, island arcs, oceanic plateaux and oceanic plates, which were amalgamated and accreted in Early Palaeozoic to Early Permian times. The establishment of the CAOB collage was followed by strike-slip movements and affected by intraplate magmatism, linked to mantle plume activity, best exemplified by the 250 Ma Siberian Traps and the 280 Ma Tarim event. In northern Xinjiang, there ale numerous and economically important mineral systems. In this contribution we describe a selection of representative mineral deposits, including subduction-related porphyry and epithermal deposits, volcanogenic massive sulphides and skarn systems. Shear zone-hosted Au lodes may have first formed as intrusion-related and subsequently re-worked during strike-slip deformation. Intraplate magmatism led to the emplacement of concentrically zoned （Alaskan-style） mafic-ultramafic intrusions, many of which host orthomagmatic sulphide deposits. A huge belt of pegmatites in the Altay orogen, locally hosts world-class rare metal deposits. Roll-front,
基金Project supported by the foundation of Chinese Academy of Sciences (Grant No. KZ951-A1-402)the State Science and Technology Committee (Grant No. 95-pre-40)the Chinese Nature Science Foundation (Grant No. 49672140)
文摘On the basis of a newly-constructed record of magnetic susceptibility (SUS) and the depositional rate change of eolian loess-red clay sequences in the last 7.2 Ma BP from the hea Plateau, together with a cornperison of a record of °18O values from the equatorial East Pacific Ocean and eolian Quartz flux variations fmm the North Pacific Ocean, the evolutiomuy process of the Late Cenozoic Great Glaciation in the Northern Hemisphere can be divided into three stages: the arrival stage around 7.2–3.4 Ma BP, the initial stage at about 3.4—2.6 Ma BP, and the Great Ice Age since 2.6 Ma BP. The evolution of the East Asian monsoon is characterized by paid winter and summer monsoons, and it is basically composed of the initial stage of weak winter and summer monsoons, the transitional stage of simultaneous increase in intensity of winter and summer monsoons, and the prevailing stage of strong winter and week summer monsoons, or weak winter and strong summer monsoons. The Late Cenowic global tectonic uplift, paaicdarly the Qinghai-Xizang Plateau uplift and the associated CO2 concentration variation, controls the dng processes of the onset of Great Glaciation and the long-term changes of East Asian monsoom climate in the Northern Hemisphere to a large extent. The accelerating uplift of the Qinghai-Xizang Plateau between 3.4 and 2.6 Ma BP provided an important driving force to global climiatic change.
文摘Eclogite from the Northern Dabie Mountain is a new finding by the authors. These eclogites in foliated perdotite are enveloped by banded gneiss and occur in the mafic-ultramafic rock belt. They are mainly composed of omphacite, garnet, diopside, orthopyroxene, amphibole, plagioclase and magnetite, and a small amount of rutile, spinel, olivin and 鏾rundum. The mineral association of peak metamorphism of the eclogite is omphacite+garnet+rutile. The existence of eclogite in the Northern Dabie Mountain implies that there was an eclogitic metamorphism prior to the granulitic facies one in the mafic-ultramafic rock belt.
文摘Distribution of vegetation is closely coupled with climate; the climate controls distribution of vegetation and the vegetation type reflects regional climates. To reveal vegetation_climate relationships is the foundation for understanding the vegetation distribution and theoretically serving vegetation regionalization. Vegetation regionalization is a theoretical integration of vegetation studies and provides a base for physiogeographical regionalization as well as agriculture and forestry regionalization. Based on a brief historical overview on studies of vegetation_climate relationships and vegetation regionalization conducted in China, we review the principles, bases and major schemes of previous vegetation regionalization and discuss on several contentious boundaries of vegetation zones in the present paper. We proposed that, under the circumstances that the primary vegetation has been destroyed in most parts of China, the division of vegetation zones/regions should be based on the distribution of primary and its secondary vegetation types and climatic indices that delimit distribution of the vegetation types. This not only reveals the closed relationship between vegetation and climate, but also is feasible practically. Although there still are divergence of views on the name and their boundaries of the several vegetation zones, it is commonly accepted that there are eight major vegetation regions in China, i.e. cold temperate needleleaf forest region, temperate needleleaf and broadleaf mixed forest region, warm temperate deciduous broadleaf forest region, subtropical evergreen broadleaf forest region, tropical monsoon forest and rain forest region, temperate steppe region, temperate desert region, and Qinghai_Xizang (Tibetan) Plateau high_cold vegetation region. Analyzing characteristics of vegetation and climate of major vegetation boundaries, we suggested that: 1) Qinling Mountain_Huaihe River line is an important arid/humid climatic, but not a thermal climatic boundary, and thus can not also be regarde
基金supported by the National Natural Science Foundation of China (No. 21507146)the National Water Pollution Control and Management Technology Major Projects of China (Nos. 2012ZX07203-006 and 2012ZX07203-003)
文摘Based on water quality surveys over 2 years （July to December, in 2014 and 2015） in a typical arid fiver in northern China the Xingtai segment of the Yuyang River basin - the variation of nitrogen （N） and phosphorus （P） was analyzed. The extent of water eutrophication of this segment was also assessed using a universal index formula for eutrophic evaluation and a logarithmic power function. The results showed that the average concentration of total N （TN） was 27.2 mg/L （NH3-N, 63.5% ）, total P （TP） was 2.0 mg/L （solution reactive phosphorus, 68.8%）. Temporal and spatial variations of N and P in this segment were observed. Concentrations of N and P in the arid season were higher than those in the rainy season. Spatially, the N and P concentrations followed the same trend; i.e., higher in the city segment than in the suburbs, and decreasing along the river. The water eutrophication in the studied segment reached extremely high levels at all times （eutrophication index ≥76.3）. Spatially, its trend was clearly linked with N and P. Water shortage, pollution accumulation and a weak self-purification function are the main reasons for the prominent eutrophication in this segment.
基金supported by the National Natural Science Foundation of China(41790474)the State Oceanic Administration International Cooperation Program on Global Change and Air–Sea Interactions(GASI-IPOVAI-03)
文摘This paper reviews recent progress made by Chinese scientists on the pathways of influence of the Northern Hemisphere mid-high latitudes on East Asian climate within the framework of a“coupled oceanic-atmospheric(land-atmospheric or seaice-atmospheric)bridge”and“chain coupled bridge”.Four major categories of pathways are concentrated upon,as follows:Pathway A—from North Atlantic to East Asia;Pathway B—from the North Pacific to East Asia;Pathway C—from the Arctic to East Asia;and Pathway D—the synergistic effects of the mid-high latitudes and tropics.In addition,definitions of the terms“combined effect”,“synergistic effect”and“antagonistic effect”of two or more factors of influence or processes and their criteria are introduced,so as to objectively investigate those effects in future research.
基金supported by the National Maize Industry Technology R&D Center,Ministry of Agriculture(CRRS-02)the National Key Technology R&D Program of China(2011BAD16B14and 2013BAD07B04)+1 种基金the National Natural Science Foundation of China(31401342)the National Basic Research Program of China(2015CB150401)
文摘A two-year field experiment(2012–2013) was conducted to investigate the effects of two tillage methods and five maize straw mulching patterns on the yield, water consumption,and water use efficiency(WUE) of spring maize(Zea mays L.) in the northern Huang–Huai–Hai valley of China. Compared to rotary tillage, subsoil tillage resulted in decreases in water consumption by 6.3–7.8% and increases in maize yield by 644.5–673.9 kg ha-1, soil water content by 2.9–3.0%, and WUE by 12.7–15.2%. Chopped straw mulching led to higher yield,soil water content, and WUE as well as lower water consumption than prostrate whole straw mulching. Mulching with 50% chopped straw had the largest positive effects on maize yield, soil water content, and WUE among the five mulching treatments. Tillage had greater influence on maize yield than straw mulching, whereas straw mulching had greater influence on soil water content, water consumption, and WUE than tillage. These results suggest that 50% chopped straw mulching with subsoil tillage is beneficial in spring maize production aiming at high yield and high WUE in the Huang–Huai–Hai valley.
基金financially supporting the research under grants No.1212011221111,Sinoprobe-02-01 and 2006DFB21330 respectively
文摘Recent mapping and seismic survey reveal that intensive compression during the Early Cenozoic in the Qiangtang block of the central Tibetan Plateau formed an extensive complex of thrust sheets that moved relatively southward along several generally north-dipping great thrust systems. Those at the borders of the ~450 km wide block show it overrides the Lhasa block to the south and is overridden by the Hohxil-Bayanhar block to the north. The systems are mostly thin-skinned imbricate thrusts with associated folding. The thrust sheets are chiefly floored by Jurassic limestone that apparently slid over Triassic sandstone and shale, which is locally included, and ramped upward and over Paleocene-Eocene red-beds. Some central thrusts scooped deeper and carried up Paleozoic metamorphic rock, Permian carbonate and granite to form a central uplift that divides the Qiangtang block into two parts. These systems and their associated structures are unconformably overlain by little deformed Late Eocene-Oligocene volcanic rock or capped by Miocene lake beds. A thrust system in the northern part of the block, as well as one in the northern part of the adjacent Lhasa block, dip to the south and appear to be due to secondary adjustments within the thrust sheets. The relative southward displacement across this Early Cenozoic mega thrust system is in excess of 150 km in the Qiangtang block, and the average southward slip-rate of the southern Qiangtang thrusts ranged from 5.6 mm to 7.4 mm/a during the Late Eocene-Oligocene. This Early Cenozoic thrusting ended before the Early Miocene and was followed by Late Cenozoic crustal extension and strike-slip faulting within the Qiangtang block. The revelation and understanding of these thrust systems are very important for the evaluation of the petroleum resources of the region.
基金This work was supported by the Chinese Academy of Sciences(Grant Nos.KZCX1-Y-03 and KZ951-A1-404).
文摘The Pengjiakuang, Dazhuangzi and Fayunkuang gold deposits, located on the northern margin of the Mesozoic Jiaolai Basin, east of Shandong Province, are controlled by a low-angle normal fault. Gold ores are typically brecciated, veinlet and disseminated. The Ar-Ar and Rb-Sr isochron dating methods were adopted to date ores and lamprophyre dike. The results indicate that the age of the Pengjiakuang gold deposit is 117.33—118.42 Ma, that of the Dazhuangzi gold deposit is 117.39 Ma, and that of the Fayunkuang gold deposit is (128.49±7.2) Ma. The consistency in metallogenic age between the gold deposits on the margin of the Jiaolai Basin and the gold deposits (115—126 Ma) of the northern uplift area suggests that both were formed in the same metallogenic period. That is to say, the large-scale metallogeny of the Jiaodong region took place in late-Yanshannian ((120±10) Ma).
