Recently, the importance of magnesium in anesthetic practice has been highlighted, its anesthetic effect is also shown. The administration of magnesium led to a significant reduction in the requirements of anaesthetic...Recently, the importance of magnesium in anesthetic practice has been highlighted, its anesthetic effect is also shown. The administration of magnesium led to a significant reduction in the requirements of anaesthetic drugs (such as non-depolarizing neuromuscular blockers, opioids and propofol) during general anesthesia, but increased anesthetic drugs’ efficiency. The mechanism of magnesium on clinical anesthesia included: magnesium works as a physiological antagonist of calcium, also as an antagonist of N-methyl-D-aspartate (NMDA) receptors in nerve system and muscular system, and magnesium also inhibits neural transmitters’ release from synapsesl.展开更多
文摘Recently, the importance of magnesium in anesthetic practice has been highlighted, its anesthetic effect is also shown. The administration of magnesium led to a significant reduction in the requirements of anaesthetic drugs (such as non-depolarizing neuromuscular blockers, opioids and propofol) during general anesthesia, but increased anesthetic drugs’ efficiency. The mechanism of magnesium on clinical anesthesia included: magnesium works as a physiological antagonist of calcium, also as an antagonist of N-methyl-D-aspartate (NMDA) receptors in nerve system and muscular system, and magnesium also inhibits neural transmitters’ release from synapsesl.
