In order to improve the quality of sinter produced by Baiyunebo iron ore concentrate,the effects of compound silicate gangue containing kalium and natrium on formation of complex calcium ferrite were studied using min...In order to improve the quality of sinter produced by Baiyunebo iron ore concentrate,the effects of compound silicate gangue containing kalium and natrium on formation of complex calcium ferrite were studied using mini-sintering test device,optical microscope（OM） analysis and scanning electron microscope（SEM）/energy dispersive X-ray spectroscopy（EDX） analysis.The results show that with the increasing of K2O and Na2O content in sintering samples,K2O and Na2O highly enriched in the glassy phases,the contents of complex calcium ferrite and hematite in sinter decreased and the porosity increased;the mineral microstructure exhibited large cavities and thin framework and became inhomogeneous.The compound silicate gangue containing kalium and natrium significantly inhibited the generation of complex calcium ferrite（SFCA）.When the content of K2O and Na2O was higher in samples,a part of K2O and Na2O entered into complex calcium ferrite,which caused the fine grains of SFCA with acicular and columnar to agglomerate into coarse grains,and its bonding effect to iron oxides reduced.The content of K2O and Na2O in sinter had effects on quantity,composition and morphology of complex calcium ferrite.展开更多
Radio-and chemo-sensitizing effects of a new sensitizer, metronidazol amino acidum natrium (CMNa), were studied by the methods of cell surviving fraction (in viiro), tumor growth delay (in vivo) and clinical observati...Radio-and chemo-sensitizing effects of a new sensitizer, metronidazol amino acidum natrium (CMNa), were studied by the methods of cell surviving fraction (in viiro), tumor growth delay (in vivo) and clinical observation. When the hypoxic V79 cells were exposed to γ-ray and CMNa, the cell surviving fraction decreased markedly as compared with radiation alone. The sensitizer enhancement ratio (SER) value was 1. 26-2. 32. When the mice bearing Lewis . B16 melanoma or EMT6 tumors were treated with single dose or fractionated radiation (with or without CMNa) or with antitumor agents (with or without CMNa) the tumor increasing velocity slowed down and the days of tumor growth delay increased significantly when CMNa was given simultaneously.In 96 cases of lung cancer and 80 cases of esophageal cancer patients treated with routine chemotherapy or radiotherapy combined with CMNa, the percentage of CR+PR increased significantly. These results showed that CMNa may be an effective radio- and chemo-sensitizer.展开更多
Rechargeable batteries based on solid-state electrolytes are of great interest and importance for the next-generation energy storage due to their high energy output and improved safety.For building the solid-state bat...Rechargeable batteries based on solid-state electrolytes are of great interest and importance for the next-generation energy storage due to their high energy output and improved safety.For building the solid-state batteries,Na_(3)Zr_(2)Si_(2)PO_(12)(NZSP)represents a promising candidate as it features high chemical stability against air exposure and a high Na^(+)conductivity.NZSP pellets were usually calcined at a high temperature,and the high volatility of Na and P elements easily led to the formation of impurity phase.In this work,the effects of calcination temperature and stoichiometry on the phase purity and ionic conductivity of the NZSP electrolyte were studied.At an elevated sintering temperature,the NZSP electrolyte showed a high ionic conductivity owing to decreased porosity,and the highest ionic conductivity at 30℃was observed to be 2.75×10^(-5)S·cm^(-1)with an activation energy of 0.41 eV.For the stoichiometry,the introduction of 5 mol%excessive P results in formation of more Na_(3)PO_(4) and glass-like phase at the grain boundary,which caused the blurred grain boundary and reduced grain barrier,and effectively suppressed Na dendrite growth,then accounted for improved cycling performance of a Na‖Na symmetric cell.Our work provided insights on reasonable design and preparation of NZSP electrolyte towards practical realization of solid-state Na-metal batteries.展开更多
OBJECTIVE: To explore the effects of Tanshinone combined with western medicine on clinical symptoms and cardiac function in patients with acute heart failure. METHODS: The medical records of 96 patients with acute hea...OBJECTIVE: To explore the effects of Tanshinone combined with western medicine on clinical symptoms and cardiac function in patients with acute heart failure. METHODS: The medical records of 96 patients with acute heart failure were randomly divided into 2 groups(48 cases in observation group and 48 cases in control group). The control group was treated with conventional western medicine, and the observation group was treated with Tanshinone IIA sulfonic acid natrium on the basis of western medicine. The traditional Chinese medicine(TCM) syndromes scores before and after treatment(after 28 d of treatment), clinical efficacy, and cardiac echocardiographic indexes and serum biochemical indicators before and after treatment were observed in the 2 groups. RESULTS: After treatment, the scores of TCM syndromes in the 2 groups were significantly decreased(P < 0.05), and the change in observation group was significantly greater than that in control group(P < 0.05). The total clinical effective rate in observation group was significantly higher than that in control group(91.67% vs 75.00%)(P < 0.05). After treatment, the echocardiographic indexes of left ventricular end-diastolic diameter(LVEDD) and left ventricular end-systolic diameter(LVESD) values were significantly reduced in the 2 groups while the left ventricular ejection fraction(LVEF) and stroke volume(SV) value were significantly increased, and the changes in observation group were significantly larger than those in control group(P < 0.05). After treatment, the levels of serum nuclear factor-kappaB(NF-KB), interleukin-1β(IL-1β) and N-terminal pro-brain natriuretic peptide(NT-proBNP) were significantly decreased in the 2 groups(P < 0.05), while the 6-keto-prostaglandin F1α(6-ketoPGF1α) level was significantly increased. And the changes in observation group were significantly greater than those in control group(P < 0.05). CONCLUSION: Tanshinone combined with western medicine can significantly improve the clinical symptoms of patients with acute heart failure, i展开更多
基金Item Sponsored by National Natural Science Foundation of China(50944049)
文摘In order to improve the quality of sinter produced by Baiyunebo iron ore concentrate,the effects of compound silicate gangue containing kalium and natrium on formation of complex calcium ferrite were studied using mini-sintering test device,optical microscope（OM） analysis and scanning electron microscope（SEM）/energy dispersive X-ray spectroscopy（EDX） analysis.The results show that with the increasing of K2O and Na2O content in sintering samples,K2O and Na2O highly enriched in the glassy phases,the contents of complex calcium ferrite and hematite in sinter decreased and the porosity increased;the mineral microstructure exhibited large cavities and thin framework and became inhomogeneous.The compound silicate gangue containing kalium and natrium significantly inhibited the generation of complex calcium ferrite（SFCA）.When the content of K2O and Na2O was higher in samples,a part of K2O and Na2O entered into complex calcium ferrite,which caused the fine grains of SFCA with acicular and columnar to agglomerate into coarse grains,and its bonding effect to iron oxides reduced.The content of K2O and Na2O in sinter had effects on quantity,composition and morphology of complex calcium ferrite.
文摘Radio-and chemo-sensitizing effects of a new sensitizer, metronidazol amino acidum natrium (CMNa), were studied by the methods of cell surviving fraction (in viiro), tumor growth delay (in vivo) and clinical observation. When the hypoxic V79 cells were exposed to γ-ray and CMNa, the cell surviving fraction decreased markedly as compared with radiation alone. The sensitizer enhancement ratio (SER) value was 1. 26-2. 32. When the mice bearing Lewis . B16 melanoma or EMT6 tumors were treated with single dose or fractionated radiation (with or without CMNa) or with antitumor agents (with or without CMNa) the tumor increasing velocity slowed down and the days of tumor growth delay increased significantly when CMNa was given simultaneously.In 96 cases of lung cancer and 80 cases of esophageal cancer patients treated with routine chemotherapy or radiotherapy combined with CMNa, the percentage of CR+PR increased significantly. These results showed that CMNa may be an effective radio- and chemo-sensitizer.
基金financially supported by the National Natural Science Foundation of China(Nos.51902238 and 52172234)the Fundamental Research Funds for the Central Universities(Nos.2020IVA069,2020IVB043 and 2021IVA020B)
文摘Rechargeable batteries based on solid-state electrolytes are of great interest and importance for the next-generation energy storage due to their high energy output and improved safety.For building the solid-state batteries,Na_(3)Zr_(2)Si_(2)PO_(12)(NZSP)represents a promising candidate as it features high chemical stability against air exposure and a high Na^(+)conductivity.NZSP pellets were usually calcined at a high temperature,and the high volatility of Na and P elements easily led to the formation of impurity phase.In this work,the effects of calcination temperature and stoichiometry on the phase purity and ionic conductivity of the NZSP electrolyte were studied.At an elevated sintering temperature,the NZSP electrolyte showed a high ionic conductivity owing to decreased porosity,and the highest ionic conductivity at 30℃was observed to be 2.75×10^(-5)S·cm^(-1)with an activation energy of 0.41 eV.For the stoichiometry,the introduction of 5 mol%excessive P results in formation of more Na_(3)PO_(4) and glass-like phase at the grain boundary,which caused the blurred grain boundary and reduced grain barrier,and effectively suppressed Na dendrite growth,then accounted for improved cycling performance of a Na‖Na symmetric cell.Our work provided insights on reasonable design and preparation of NZSP electrolyte towards practical realization of solid-state Na-metal batteries.
文摘OBJECTIVE: To explore the effects of Tanshinone combined with western medicine on clinical symptoms and cardiac function in patients with acute heart failure. METHODS: The medical records of 96 patients with acute heart failure were randomly divided into 2 groups(48 cases in observation group and 48 cases in control group). The control group was treated with conventional western medicine, and the observation group was treated with Tanshinone IIA sulfonic acid natrium on the basis of western medicine. The traditional Chinese medicine(TCM) syndromes scores before and after treatment(after 28 d of treatment), clinical efficacy, and cardiac echocardiographic indexes and serum biochemical indicators before and after treatment were observed in the 2 groups. RESULTS: After treatment, the scores of TCM syndromes in the 2 groups were significantly decreased(P < 0.05), and the change in observation group was significantly greater than that in control group(P < 0.05). The total clinical effective rate in observation group was significantly higher than that in control group(91.67% vs 75.00%)(P < 0.05). After treatment, the echocardiographic indexes of left ventricular end-diastolic diameter(LVEDD) and left ventricular end-systolic diameter(LVESD) values were significantly reduced in the 2 groups while the left ventricular ejection fraction(LVEF) and stroke volume(SV) value were significantly increased, and the changes in observation group were significantly larger than those in control group(P < 0.05). After treatment, the levels of serum nuclear factor-kappaB(NF-KB), interleukin-1β(IL-1β) and N-terminal pro-brain natriuretic peptide(NT-proBNP) were significantly decreased in the 2 groups(P < 0.05), while the 6-keto-prostaglandin F1α(6-ketoPGF1α) level was significantly increased. And the changes in observation group were significantly greater than those in control group(P < 0.05). CONCLUSION: Tanshinone combined with western medicine can significantly improve the clinical symptoms of patients with acute heart failure, i
